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The map label for this gene is nanR [H]

Identifier: 13475837

GI number: 13475837

Start: 5772217

End: 5772930

Strand: Direct

Name: nanR [H]

Synonym: mlr7008

Alternate gene names: 13475837

Gene position: 5772217-5772930 (Clockwise)

Preceding gene: 13475834

Following gene: 13475849

Centisome position: 82.04

GC content: 60.5

Gene sequence:

>714_bases
ATGAACCGTTCGGAACCAATTGTCCGGCGCAAGCTTTCCGACGAGGTCTTCTTGCGGCTGAAGCGCCTGATCACCAGCGG
CGAGTTGCAGCCGGGCGACGACATGCCGTCAGAGCGCGAATTGATGGAGCGCTTCGAGGTTGGCCGGCCGGCCATCCGCG
AGGCGATGCAGGCGCTGAGCAATATGGGCCTCGTCGCCATCTCGCATGGCGAGCGGGCCAAGGTGCTGCAGCTCACCGCC
AAGTCGATCATCAAACAGGTCGATGGCGCGGCCAAGATCATCCTGTCGTCGTCGAAGGACACGCTCGAGCACCTCAAGAC
CGCGCGCATCTTCTTCGAGCGTGGCATGGTCAGGGAAGCCGCCGAGAAGGCCACCGTCGAGGATGTGCAGCGGCTCAAGG
CAACCGTCGCCGAGCAGCGTGCCGCGCGAGGTGATTCCGAAGCTTTCATTTCCGCCGACATGAAATTCCACACCCAGATC
GCGGCGATATCGGGCAACCCGATCTATGTCGCCGTCAGCGAGGCGATGCTGGGCTGGCTGAAGGAGTATCATACTGAAAT
GCTGATCTGGACCGGCAAGGAACAGTTCACGCTGACCGAGCACGAAGAGATCATCGGCCGCATCGAGAAGAAAGATGCCG
ATGGCGCCGAGAAGGCGATGATCAAGCATCTGGAGCGCTCGCGCGCCCTCTATGTGATGAATTCTGAAAAGTAA

Upstream 100 bases:

>100_bases
GACATATCCCGCTGGAAGTTTTGCGAGGTCGAAGCCCGCATTTCCGCGAATTGTGGCGGCGGTGTTAGATAGGGCCGGGT
CAAGGGAGTGATTCGCGACG

Downstream 100 bases:

>100_bases
TCTGATTCAGCCGATCCGCGCGATCGCGTAGGGTGCCATAACAAGATGGCCTCGGCCAAACTCCGAAAGGTCGACCGCCA
CGTCGCTTGCCGTCAGGTTC

Product: transcriptional regulator NanR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MNRSEPIVRRKLSDEVFLRLKRLITSGELQPGDDMPSERELMERFEVGRPAIREAMQALSNMGLVAISHGERAKVLQLTA
KSIIKQVDGAAKIILSSSKDTLEHLKTARIFFERGMVREAAEKATVEDVQRLKATVAEQRAARGDSEAFISADMKFHTQI
AAISGNPIYVAVSEAMLGWLKEYHTEMLIWTGKEQFTLTEHEEIIGRIEKKDADGAEKAMIKHLERSRALYVMNSEK

Sequences:

>Translated_237_residues
MNRSEPIVRRKLSDEVFLRLKRLITSGELQPGDDMPSERELMERFEVGRPAIREAMQALSNMGLVAISHGERAKVLQLTA
KSIIKQVDGAAKIILSSSKDTLEHLKTARIFFERGMVREAAEKATVEDVQRLKATVAEQRAARGDSEAFISADMKFHTQI
AAISGNPIYVAVSEAMLGWLKEYHTEMLIWTGKEQFTLTEHEEIIGRIEKKDADGAEKAMIKHLERSRALYVMNSEK
>Mature_237_residues
MNRSEPIVRRKLSDEVFLRLKRLITSGELQPGDDMPSERELMERFEVGRPAIREAMQALSNMGLVAISHGERAKVLQLTA
KSIIKQVDGAAKIILSSSKDTLEHLKTARIFFERGMVREAAEKATVEDVQRLKATVAEQRAARGDSEAFISADMKFHTQI
AAISGNPIYVAVSEAMLGWLKEYHTEMLIWTGKEQFTLTEHEEIIGRIEKKDADGAEKAMIKHLERSRALYVMNSEK

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=231, Percent_Identity=38.0952380952381, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI48994955, Length=220, Percent_Identity=26.3636363636364, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI48994961, Length=213, Percent_Identity=27.6995305164319, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790032, Length=230, Percent_Identity=28.695652173913, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790780, Length=222, Percent_Identity=29.7297297297297, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787436, Length=159, Percent_Identity=29.559748427673, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI87082208, Length=240, Percent_Identity=26.25, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26739; Mature: 26739

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSEPIVRRKLSDEVFLRLKRLITSGELQPGDDMPSERELMERFEVGRPAIREAMQALS
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
NMGLVAISHGERAKVLQLTAKSIIKQVDGAAKIILSSSKDTLEHLKTARIFFERGMVREA
HCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHEEEECCHHHHHHHHHHHHHHHHHHHHHH
AEKATVEDVQRLKATVAEQRAARGDSEAFISADMKFHTQIAAISGNPIYVAVSEAMLGWL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEEECCCEEEEEHHHHHHHHH
KEYHTEMLIWTGKEQFTLTEHEEIIGRIEKKDADGAEKAMIKHLERSRALYVMNSEK
HHHCCCEEEEECCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCC
>Mature Secondary Structure
MNRSEPIVRRKLSDEVFLRLKRLITSGELQPGDDMPSERELMERFEVGRPAIREAMQALS
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
NMGLVAISHGERAKVLQLTAKSIIKQVDGAAKIILSSSKDTLEHLKTARIFFERGMVREA
HCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHEEEECCHHHHHHHHHHHHHHHHHHHHHH
AEKATVEDVQRLKATVAEQRAARGDSEAFISADMKFHTQIAAISGNPIYVAVSEAMLGWL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEEECCCEEEEEHHHHHHHHH
KEYHTEMLIWTGKEQFTLTEHEEIIGRIEKKDADGAEKAMIKHLERSRALYVMNSEK
HHHCCCEEEEECCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA