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The map label for this gene is aidB [H]

Identifier: 13475804

GI number: 13475804

Start: 5735093

End: 5736844

Strand: Direct

Name: aidB [H]

Synonym: mlr6975

Alternate gene names: 13475804

Gene position: 5735093-5736844 (Clockwise)

Preceding gene: 13475803

Following gene: 13475805

Centisome position: 81.51

GC content: 60.96

Gene sequence:

>1752_bases
ATGACTTTTGAAGCACCATTAAAGGACTTGATGTTCAATATCACCCACATCGCGCCATGGTCCGGCGATGCGATGGGTGA
TCTCGAGACGGCCGCAGCTGTCCTGGACGAGTTCGGCCGCTTTTGTGCCGAGGAAATCGCGCCGCTGAATGCCGCGGGCG
ACCGCATCGGCTCGCACTGGGACGGAGGTCTCGTCCAAACGCCGCCCGGATTCCGTGAGGCCTATGCCAAGTTCATGGAC
ATGGGCTGGCAGGGGTTGCGTCATCCTTCGGAATTTGGCGGGCATGATATGCCCCGCGCTGTCGCCGCTGCGGCGACCGA
AATCATCAACGCGGCCAATATGAGTTTTGCGCTATGTCCTCTTTTGACCGATGGCGCGATCGAGGCGCTTCTGCGTTTCG
GGTCGCCTGAAATCCAACAGACCTATCTGCACAAGCTGGTTTCCGGCAAATGGACCGGCACGATGAATCTGACCGAGTCG
CAGGCGGGCAGCGATCTGGCCCTGATACGGACAAGAGCCGAACGCCAGGCGAATGGCACCTATCAGATCTCCGGAACAAA
GATCTTCATCACCTATGGCGAGCATGATCTGGCCGAGAATATCATTCACCTCGTCCTTGCTCGAACGCCTGGCGCGCCCG
ACGGCGTCAAGGGCATCAGCCTCTTTCTCGTGCCGAAACTTCTGGTGGGCGAAAGTGGCGAACCCGGCGCGCAAAATTCG
CTCCGCTGCCAAAGCATCGAACACAAGCTTGGCGTCAGGGCGAGCCCGACCTGCATGCTGGAATTCGAAGGCGCCACCGG
CTTTCTGATTGGCCGCGAAAACGCCGGGCTGGAGATCATGTTCACGATGATGAACGCGGCACGCTTCGCCGTGGGCGTTC
AAGGGGTTGCGATAGCAGAGCGTGCCTATCAGATGGCTCTATCCTACGCAAAGACCCGTATGCAGGGCCGTCCAGTCGAT
GGCAGCGCTTTCGAGGCAGTTCCCATTATCCGTCACCCGGATGTCCGCCGCATGCTGGCGCACATGCGCGCCACGACCGA
AGGGGGCCGTGCCCTTGCCGCCGCTGCCGCGGGATGGCAGGACCGTGCGCAGTTTGCCGCCACGCCGGAACTGAGAGCGG
AGGCCCTGGCGATAGGTGAATTTCTTGTGCCGTTGGTCAAGGGCTTCTGCACCGAGATGAGCCTTCAGACAGCTTCAACT
GGGGTCCAGATTTTTGGTGGCATGGGGTTTATCGAAGAAACCGGCGTTGCCCAGTACTACCGTGACGCCCGAATCTTGCC
GATCTACGAGGGCACGACGGCCATCCAGGCCAATGATCTGCTGGGGCGCAAGACGCTTCGAGACGGTGGATCAACGGCGA
GACGCCTCGCTGCAATGATAACTCAGACAGAAACTGCGCTACGGCAAGGCTCGCCCTTGGCGCAGGAGATCGCGGCGCAG
CTGTCCTGCGCGCGGCAAGCATTCGAGACGGTCGTTGCCCATCTGGTTGCGGTCAAGCCAGCGGATTTGAACGCCGCTTA
TGCAGGCGCCGTGCCCTACCTGATGCTGGCTGGCAACCTTGTCGCGGGCTGGCAGCTGGCACGCTCGGTCCTTATCGCCG
AAGCGGGGCTGGAGGACGGCCAAGATCCCGATTTCATGACCGCCAAGATCGCCACGGCACGGTTCTACGCCCAACACATT
CTCGGGGAGACCGACCTTCAGCGAGCCCGGGTCATGGACGGCGCCGCAAGCCTGTTGGACATCGAATTCTGA

Upstream 100 bases:

>100_bases
CGCCGAAAACGGTGGTGTTCGGCCCTTTGCCAAAAACCGCGACAGGCAAGATTCAGAAGTTCATTCTGCGGGCGGCAGCC
CGTGACCTGGGGCCTCAGGC

Downstream 100 bases:

>100_bases
ATAGAACAATCAACCCTCTTCAACTCGGGAACAGGACCGTACCATGGCCATCCAAATCGACATCACCCGATACGAGAACC
TTGCCGTCGAGGCTCATGAC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 582

Protein sequence:

>583_residues
MTFEAPLKDLMFNITHIAPWSGDAMGDLETAAAVLDEFGRFCAEEIAPLNAAGDRIGSHWDGGLVQTPPGFREAYAKFMD
MGWQGLRHPSEFGGHDMPRAVAAAATEIINAANMSFALCPLLTDGAIEALLRFGSPEIQQTYLHKLVSGKWTGTMNLTES
QAGSDLALIRTRAERQANGTYQISGTKIFITYGEHDLAENIIHLVLARTPGAPDGVKGISLFLVPKLLVGESGEPGAQNS
LRCQSIEHKLGVRASPTCMLEFEGATGFLIGRENAGLEIMFTMMNAARFAVGVQGVAIAERAYQMALSYAKTRMQGRPVD
GSAFEAVPIIRHPDVRRMLAHMRATTEGGRALAAAAAGWQDRAQFAATPELRAEALAIGEFLVPLVKGFCTEMSLQTAST
GVQIFGGMGFIEETGVAQYYRDARILPIYEGTTAIQANDLLGRKTLRDGGSTARRLAAMITQTETALRQGSPLAQEIAAQ
LSCARQAFETVVAHLVAVKPADLNAAYAGAVPYLMLAGNLVAGWQLARSVLIAEAGLEDGQDPDFMTAKIATARFYAQHI
LGETDLQRARVMDGAASLLDIEF

Sequences:

>Translated_583_residues
MTFEAPLKDLMFNITHIAPWSGDAMGDLETAAAVLDEFGRFCAEEIAPLNAAGDRIGSHWDGGLVQTPPGFREAYAKFMD
MGWQGLRHPSEFGGHDMPRAVAAAATEIINAANMSFALCPLLTDGAIEALLRFGSPEIQQTYLHKLVSGKWTGTMNLTES
QAGSDLALIRTRAERQANGTYQISGTKIFITYGEHDLAENIIHLVLARTPGAPDGVKGISLFLVPKLLVGESGEPGAQNS
LRCQSIEHKLGVRASPTCMLEFEGATGFLIGRENAGLEIMFTMMNAARFAVGVQGVAIAERAYQMALSYAKTRMQGRPVD
GSAFEAVPIIRHPDVRRMLAHMRATTEGGRALAAAAAGWQDRAQFAATPELRAEALAIGEFLVPLVKGFCTEMSLQTAST
GVQIFGGMGFIEETGVAQYYRDARILPIYEGTTAIQANDLLGRKTLRDGGSTARRLAAMITQTETALRQGSPLAQEIAAQ
LSCARQAFETVVAHLVAVKPADLNAAYAGAVPYLMLAGNLVAGWQLARSVLIAEAGLEDGQDPDFMTAKIATARFYAQHI
LGETDLQRARVMDGAASLLDIEF
>Mature_582_residues
TFEAPLKDLMFNITHIAPWSGDAMGDLETAAAVLDEFGRFCAEEIAPLNAAGDRIGSHWDGGLVQTPPGFREAYAKFMDM
GWQGLRHPSEFGGHDMPRAVAAAATEIINAANMSFALCPLLTDGAIEALLRFGSPEIQQTYLHKLVSGKWTGTMNLTESQ
AGSDLALIRTRAERQANGTYQISGTKIFITYGEHDLAENIIHLVLARTPGAPDGVKGISLFLVPKLLVGESGEPGAQNSL
RCQSIEHKLGVRASPTCMLEFEGATGFLIGRENAGLEIMFTMMNAARFAVGVQGVAIAERAYQMALSYAKTRMQGRPVDG
SAFEAVPIIRHPDVRRMLAHMRATTEGGRALAAAAAGWQDRAQFAATPELRAEALAIGEFLVPLVKGFCTEMSLQTASTG
VQIFGGMGFIEETGVAQYYRDARILPIYEGTTAIQANDLLGRKTLRDGGSTARRLAAMITQTETALRQGSPLAQEIAAQL
SCARQAFETVVAHLVAVKPADLNAAYAGAVPYLMLAGNLVAGWQLARSVLIAEAGLEDGQDPDFMTAKIATARFYAQHIL
GETDLQRARVMDGAASLLDIEF

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=440, Percent_Identity=27.2727272727273, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI4557233, Length=336, Percent_Identity=31.547619047619, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI21361497, Length=372, Percent_Identity=29.0322580645161, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI226958412, Length=414, Percent_Identity=23.9130434782609, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI226958414, Length=382, Percent_Identity=24.0837696335079, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4557235, Length=394, Percent_Identity=27.4111675126904, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI76496475, Length=394, Percent_Identity=27.4111675126904, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI4501857, Length=412, Percent_Identity=24.2718446601942, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI187960098, Length=411, Percent_Identity=27.2506082725061, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4557231, Length=411, Percent_Identity=27.2506082725061, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI7656849, Length=424, Percent_Identity=26.4150943396226, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI87082384, Length=333, Percent_Identity=30.03003003003, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI87081958, Length=391, Percent_Identity=29.6675191815857, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17508101, Length=368, Percent_Identity=27.1739130434783, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17506239, Length=368, Percent_Identity=27.1739130434783, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI86563381, Length=332, Percent_Identity=28.0120481927711, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI86563383, Length=332, Percent_Identity=28.0120481927711, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17538396, Length=435, Percent_Identity=26.2068965517241, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71985184, Length=378, Percent_Identity=27.2486772486773, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17570075, Length=387, Percent_Identity=25.3229974160207, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=415, Percent_Identity=26.7469879518072, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17533517, Length=421, Percent_Identity=24.9406175771971, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=321, Percent_Identity=28.3489096573209, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=413, Percent_Identity=24.9394673123487, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551932, Length=413, Percent_Identity=23.0024213075061, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=303, Percent_Identity=25.7425742574257, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI32563615, Length=235, Percent_Identity=26.3829787234043, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=252, Percent_Identity=26.5873015873016, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24660351, Length=439, Percent_Identity=29.1571753986333, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=28.3783783783784, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281363737, Length=422, Percent_Identity=24.6445497630332, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355753, Length=440, Percent_Identity=27.0454545454545, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646207, Length=367, Percent_Identity=25.6130790190736, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24666513, Length=359, Percent_Identity=27.0194986072423, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19920834, Length=326, Percent_Identity=29.1411042944785, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 62524; Mature: 62393

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFEAPLKDLMFNITHIAPWSGDAMGDLETAAAVLDEFGRFCAEEIAPLNAAGDRIGSHW
CCCCCCHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCC
DGGLVQTPPGFREAYAKFMDMGWQGLRHPSEFGGHDMPRAVAAAATEIINAANMSFALCP
CCCCCCCCCCHHHHHHHHHHCCHHHCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCEEEHH
LLTDGAIEALLRFGSPEIQQTYLHKLVSGKWTGTMNLTESQAGSDLALIRTRAERQANGT
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCE
YQISGTKIFITYGEHDLAENIIHLVLARTPGAPDGVKGISLFLVPKLLVGESGEPGAQNS
EEEECEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
LRCQSIEHKLGVRASPTCMLEFEGATGFLIGRENAGLEIMFTMMNAARFAVGVQGVAIAE
CHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCEEEHHHHHHHHHHHCCCHHHHHH
RAYQMALSYAKTRMQGRPVDGSAFEAVPIIRHPDVRRMLAHMRATTEGGRALAAAAAGWQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCH
DRAQFAATPELRAEALAIGEFLVPLVKGFCTEMSLQTASTGVQIFGGMGFIEETGVAQYY
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHCCHHHHH
RDARILPIYEGTTAIQANDLLGRKTLRDGGSTARRLAAMITQTETALRQGSPLAQEIAAQ
HCCEEEEEECCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LSCARQAFETVVAHLVAVKPADLNAAYAGAVPYLMLAGNLVAGWQLARSVLIAEAGLEDG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
QDPDFMTAKIATARFYAQHILGETDLQRARVMDGAASLLDIEF
CCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCHHHHEEECC
>Mature Secondary Structure 
TFEAPLKDLMFNITHIAPWSGDAMGDLETAAAVLDEFGRFCAEEIAPLNAAGDRIGSHW
CCCCCHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCC
DGGLVQTPPGFREAYAKFMDMGWQGLRHPSEFGGHDMPRAVAAAATEIINAANMSFALCP
CCCCCCCCCCHHHHHHHHHHCCHHHCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCEEEHH
LLTDGAIEALLRFGSPEIQQTYLHKLVSGKWTGTMNLTESQAGSDLALIRTRAERQANGT
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCE
YQISGTKIFITYGEHDLAENIIHLVLARTPGAPDGVKGISLFLVPKLLVGESGEPGAQNS
EEEECEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
LRCQSIEHKLGVRASPTCMLEFEGATGFLIGRENAGLEIMFTMMNAARFAVGVQGVAIAE
CHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCEEEHHHHHHHHHHHCCCHHHHHH
RAYQMALSYAKTRMQGRPVDGSAFEAVPIIRHPDVRRMLAHMRATTEGGRALAAAAAGWQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCH
DRAQFAATPELRAEALAIGEFLVPLVKGFCTEMSLQTASTGVQIFGGMGFIEETGVAQYY
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHCCHHHHH
RDARILPIYEGTTAIQANDLLGRKTLRDGGSTARRLAAMITQTETALRQGSPLAQEIAAQ
HCCEEEEEECCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LSCARQAFETVVAHLVAVKPADLNAAYAGAVPYLMLAGNLVAGWQLARSVLIAEAGLEDG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
QDPDFMTAKIATARFYAQHILGETDLQRARVMDGAASLLDIEF
CCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]