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The map label for this gene is chaA [C]

Identifier: 13475771

GI number: 13475771

Start: 5700785

End: 5701933

Strand: Direct

Name: chaA [C]

Synonym: mlr6933

Alternate gene names: 13475771

Gene position: 5700785-5701933 (Clockwise)

Preceding gene: 13475770

Following gene: 13475772

Centisome position: 81.02

GC content: 59.97

Gene sequence:

>1149_bases
GTGCGCGAATGCAGCCAAGGTTCGCAGAAGCGCACGGGGGCTTGGATGAGCGGTTTCGGACGATCGGTGACTTCCTATGC
GATGCCGCTGGCCGCCCTGGTGATGGCTGTTGCGGTCAGATCCAGCGGGCTGTCGGTGGACCAGGGTTCGCTGAACGCCA
GGATCCTTGTCGGTGCGCTGTCGAGTGCGATCATGTTCGTCACCATTTTCGTGGTGCTCGACCACGCCGAGGCGGTGGCT
CGGCGGGTAGGGGAGCCGTACGGCACGCTGGTGCTGACCTTTGCCGTGACGGCAATCGAAGTGTCGATCATCGTTTCCAT
GATGCTGCATGGAGAGAACAACCCGACGCTGGCACGGGAGTCCGTCTTCTCGACGGTGATGATCACATCCACCGGCGTTG
TCGGCATGTGTCTCGCGCTTGGCGGCTGGCGTCATCGCAAGCAGGCCATCGTACGGCAAGGGACCAGTGCCTATCTGGCG
GTTCTGATCGCGCTGACCGTCATGACGCTTATTCTGCCGACCTATACCCAGGCCACGGATCCCGGCACGTTTTCGGCAGC
CCAACTTGGTTTCGTCAGCGTCCTTTCAGTGCTGCTCTATGCAAGCTTCGTGTTCGCGCAGACCGTCCGGCACCGGGAAG
ACTTTATCCAGGGACAACCACACGACGTTTCGGTGCGCGCTGCCCCTCACGGGAACATCTCTGCCAGTGCTCTGCTGCTG
ATGGCCGGGCTGATCGGAATTGTCATGCTCGCCGAGCAGGTCGCGGCAAGCGTCGAAGATACGCTCGTTGCCTATCGGGT
GACCCAGACTGACAGCATTGTGGGGGCAATGATCGCGGGGCTGGTGTTGATGCCGGAGGCCATTTCGGCGGTGCGCGCTT
CACTCAACAACGAGCTGCAGCGCGGCTTGAATGTCGCGATGGGTTCGGCTTGCGCCACGATCGGCCTGACCATACCGGGA
GTCGCAGCCGCCAGCCTGCTGACGGGGAGAGGACTGACCCTGGGGCTGCCGGCTGCCGATGCGGTCCTCTTGGTCTTGGC
GCTTTTCATATGCAATGTAAGCTTCAGCACTGAAAGAACGACGTTCTTGACCGGAATGGTCCATCTTGTAGTGTTTTTTA
CTTATATATTTCTGATATTTATACCATGA

Upstream 100 bases:

>100_bases
CGGCAAGCCGCAAAAATTCCTGATGCGTCAGGCGATGGTCGAGGAATTGGGGCTTGTGGCGCAGAAGACGGCGTGAACGG
GTGAACGCTTCGATCTGTCG

Downstream 100 bases:

>100_bases
AATCCCTTAGATAAGCGTGCGATCAGATGCGGGCATCCGTTGATCAGGAAGCCGTTATCGACCGGGTAATCGAGAGAGCA
ATCATTCCCTTCCGCACCGA

Product: ionic transporter

Products: Na (I) [Periplasm]; Ca (II) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MRECSQGSQKRTGAWMSGFGRSVTSYAMPLAALVMAVAVRSSGLSVDQGSLNARILVGALSSAIMFVTIFVVLDHAEAVA
RRVGEPYGTLVLTFAVTAIEVSIIVSMMLHGENNPTLARESVFSTVMITSTGVVGMCLALGGWRHRKQAIVRQGTSAYLA
VLIALTVMTLILPTYTQATDPGTFSAAQLGFVSVLSVLLYASFVFAQTVRHREDFIQGQPHDVSVRAAPHGNISASALLL
MAGLIGIVMLAEQVAASVEDTLVAYRVTQTDSIVGAMIAGLVLMPEAISAVRASLNNELQRGLNVAMGSACATIGLTIPG
VAAASLLTGRGLTLGLPAADAVLLVLALFICNVSFSTERTTFLTGMVHLVVFFTYIFLIFIP

Sequences:

>Translated_382_residues
MRECSQGSQKRTGAWMSGFGRSVTSYAMPLAALVMAVAVRSSGLSVDQGSLNARILVGALSSAIMFVTIFVVLDHAEAVA
RRVGEPYGTLVLTFAVTAIEVSIIVSMMLHGENNPTLARESVFSTVMITSTGVVGMCLALGGWRHRKQAIVRQGTSAYLA
VLIALTVMTLILPTYTQATDPGTFSAAQLGFVSVLSVLLYASFVFAQTVRHREDFIQGQPHDVSVRAAPHGNISASALLL
MAGLIGIVMLAEQVAASVEDTLVAYRVTQTDSIVGAMIAGLVLMPEAISAVRASLNNELQRGLNVAMGSACATIGLTIPG
VAAASLLTGRGLTLGLPAADAVLLVLALFICNVSFSTERTTFLTGMVHLVVFFTYIFLIFIP
>Mature_382_residues
MRECSQGSQKRTGAWMSGFGRSVTSYAMPLAALVMAVAVRSSGLSVDQGSLNARILVGALSSAIMFVTIFVVLDHAEAVA
RRVGEPYGTLVLTFAVTAIEVSIIVSMMLHGENNPTLARESVFSTVMITSTGVVGMCLALGGWRHRKQAIVRQGTSAYLA
VLIALTVMTLILPTYTQATDPGTFSAAQLGFVSVLSVLLYASFVFAQTVRHREDFIQGQPHDVSVRAAPHGNISASALLL
MAGLIGIVMLAEQVAASVEDTLVAYRVTQTDSIVGAMIAGLVLMPEAISAVRASLNNELQRGLNVAMGSACATIGLTIPG
VAAASLLTGRGLTLGLPAADAVLLVLALFICNVSFSTERTTFLTGMVHLVVFFTYIFLIFIP

Specific function: Possible cation transporter [H]

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1787468, Length=362, Percent_Identity=35.3591160220994, Blast_Score=192, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 40188; Mature: 40188

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRECSQGSQKRTGAWMSGFGRSVTSYAMPLAALVMAVAVRSSGLSVDQGSLNARILVGAL
CCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SSAIMFVTIFVVLDHAEAVARRVGEPYGTLVLTFAVTAIEVSIIVSMMLHGENNPTLARE
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
SVFSTVMITSTGVVGMCLALGGWRHRKQAIVRQGTSAYLAVLIALTVMTLILPTYTQATD
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PGTFSAAQLGFVSVLSVLLYASFVFAQTVRHREDFIQGQPHDVSVRAAPHGNISASALLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHH
MAGLIGIVMLAEQVAASVEDTLVAYRVTQTDSIVGAMIAGLVLMPEAISAVRASLNNELQ
HHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLNVAMGSACATIGLTIPGVAAASLLTGRGLTLGLPAADAVLLVLALFICNVSFSTERT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHCCCCCCCHH
TFLTGMVHLVVFFTYIFLIFIP
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRECSQGSQKRTGAWMSGFGRSVTSYAMPLAALVMAVAVRSSGLSVDQGSLNARILVGAL
CCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SSAIMFVTIFVVLDHAEAVARRVGEPYGTLVLTFAVTAIEVSIIVSMMLHGENNPTLARE
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
SVFSTVMITSTGVVGMCLALGGWRHRKQAIVRQGTSAYLAVLIALTVMTLILPTYTQATD
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PGTFSAAQLGFVSVLSVLLYASFVFAQTVRHREDFIQGQPHDVSVRAAPHGNISASALLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHH
MAGLIGIVMLAEQVAASVEDTLVAYRVTQTDSIVGAMIAGLVLMPEAISAVRASLNNELQ
HHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLNVAMGSACATIGLTIPGVAAASLLTGRGLTLGLPAADAVLLVLALFICNVSFSTERT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHCCCCCCCHH
TFLTGMVHLVVFFTYIFLIFIP
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm]; Ca (II) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + Proton [Periplasm] = Proton [Cytoplasm] + Na (I) [Periplasm] Ca (II) [Cytoplasm] + Proton [Periplasm] = Ca (II) [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]