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The map label for this gene is dgdR [H]

Identifier: 13475745

GI number: 13475745

Start: 5675459

End: 5676421

Strand: Reverse

Name: dgdR [H]

Synonym: mll6897

Alternate gene names: 13475745

Gene position: 5676421-5675459 (Counterclockwise)

Preceding gene: 13475746

Following gene: 13475744

Centisome position: 80.68

GC content: 65.63

Gene sequence:

>963_bases
ATGCCGATGAAAGCGCCGCTCGATCTCGATCAGTTGCAAACCTTCATTTCGATTGCCGATACCGGCAGCTTCACGCGGGC
AGCCGAAGAGGTGCACCGGACCCAGTCGGCGGTGTCGATGCAGATGCGTCGGCTGGAGGAGCGGATAGGCAAGCCGTTGT
TCGAGAAGGAGGGGCGCAGCAACAGGCTGACGGAGGAAGGCGACAAGCTGCTCTCCTACGCAAGACGGCTGCTCTACCTC
AACCGCGAAACACTCGCCGCCTTCGACGACCAGCGGCTTGAAGGCACGATCCGCATCGGCACACCCGACGACTATGCCGA
CCGCTTCCTGCCCGAGATCATGGCGCGCTTCACCCGCTCCAATCCGCGCGTCGAGCTGACCGTCATCTGCGAGCCGACAC
CGGGGCTGGTCGAGCACATCAAGCGCGGCAATCTCGACCTGGCGCTGGTGACGCACAATGATGTGCGCGGCCAGTCGGAA
GTGGTGCGGCGCGAGCCGCTGCTGTGGGTCACCTCGGCCAATCATGCGACGCATGAAGAGGAGACGCTGCCGATGGCCTT
TGGCCGGCCGAACTGCATCTGGCGGCGCGCCGCGGTCGATGTGCTGGACCAGCAGAACCGCGACTATCGCATCCTGTTCA
CCAGCTTCTCGGCGACCGTCATCACCGCCGCGGTTCTGTCAGGCCTGGCGATCTCGGTGCTGCCGGAATGCGCGCTCAGG
CCCGGCATGCGGGTGCTGGGCGAAGCCGACGGCTTCGGCGCCCTGCCCGACTGCCGCATCGGCATCATGCGCGGCCAGAC
CTCGCGGCCGGAGATCGTCGATGCGCTCGCCCGCCACATCTCGGAGAGCCTGGACAACATCTCGGTGCCGCTCGTCGAAG
AGGCCGGGACGTTCGATTTCGCGGCACTTGCCTACGCCAAGATCAGGCGGACCAAGGCGAACCAGATCCTGCCGGGCTGG
TAG

Upstream 100 bases:

>100_bases
GATTCACATGCCTTCATGTGGATGTCAGCAATTTGCCATCGGACGATTGATTAATCCAACGAATGTTTTTAATCTTTACC
ATCAACACCAGTGATGGATC

Downstream 100 bases:

>100_bases
GAAGGATCGTGGCGCCTTGACGCGGGGCGCCAACCAGCCCCCAATCGGCCGATGAGCGAAGCAGCATCCGAATCACGCAC
CAACGCCACCGAATACACGG

Product: transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MPMKAPLDLDQLQTFISIADTGSFTRAAEEVHRTQSAVSMQMRRLEERIGKPLFEKEGRSNRLTEEGDKLLSYARRLLYL
NRETLAAFDDQRLEGTIRIGTPDDYADRFLPEIMARFTRSNPRVELTVICEPTPGLVEHIKRGNLDLALVTHNDVRGQSE
VVRREPLLWVTSANHATHEEETLPMAFGRPNCIWRRAAVDVLDQQNRDYRILFTSFSATVITAAVLSGLAISVLPECALR
PGMRVLGEADGFGALPDCRIGIMRGQTSRPEIVDALARHISESLDNISVPLVEEAGTFDFAALAYAKIRRTKANQILPGW

Sequences:

>Translated_320_residues
MPMKAPLDLDQLQTFISIADTGSFTRAAEEVHRTQSAVSMQMRRLEERIGKPLFEKEGRSNRLTEEGDKLLSYARRLLYL
NRETLAAFDDQRLEGTIRIGTPDDYADRFLPEIMARFTRSNPRVELTVICEPTPGLVEHIKRGNLDLALVTHNDVRGQSE
VVRREPLLWVTSANHATHEEETLPMAFGRPNCIWRRAAVDVLDQQNRDYRILFTSFSATVITAAVLSGLAISVLPECALR
PGMRVLGEADGFGALPDCRIGIMRGQTSRPEIVDALARHISESLDNISVPLVEEAGTFDFAALAYAKIRRTKANQILPGW
>Mature_319_residues
PMKAPLDLDQLQTFISIADTGSFTRAAEEVHRTQSAVSMQMRRLEERIGKPLFEKEGRSNRLTEEGDKLLSYARRLLYLN
RETLAAFDDQRLEGTIRIGTPDDYADRFLPEIMARFTRSNPRVELTVICEPTPGLVEHIKRGNLDLALVTHNDVRGQSEV
VRREPLLWVTSANHATHEEETLPMAFGRPNCIWRRAAVDVLDQQNRDYRILFTSFSATVITAAVLSGLAISVLPECALRP
GMRVLGEADGFGALPDCRIGIMRGQTSRPEIVDALARHISESLDNISVPLVEEAGTFDFAALAYAKIRRTKANQILPGW

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=284, Percent_Identity=32.0422535211268, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1787806, Length=242, Percent_Identity=26.8595041322314, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI157672245, Length=120, Percent_Identity=37.5, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=33.1034482758621, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788748, Length=180, Percent_Identity=28.3333333333333, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790399, Length=249, Percent_Identity=24.8995983935743, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788887, Length=179, Percent_Identity=29.0502793296089, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787589, Length=126, Percent_Identity=34.9206349206349, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87081904, Length=180, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790262, Length=149, Percent_Identity=28.8590604026846, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788297, Length=275, Percent_Identity=25.0909090909091, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI87082132, Length=124, Percent_Identity=32.258064516129, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788706, Length=142, Percent_Identity=33.8028169014084, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786401, Length=146, Percent_Identity=30.8219178082192, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787601, Length=155, Percent_Identity=25.1612903225806, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994962, Length=72, Percent_Identity=44.4444444444444, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI145693105, Length=148, Percent_Identity=25.6756756756757, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35868; Mature: 35737

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMKAPLDLDQLQTFISIADTGSFTRAAEEVHRTQSAVSMQMRRLEERIGKPLFEKEGRS
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCC
NRLTEEGDKLLSYARRLLYLNRETLAAFDDQRLEGTIRIGTPDDYADRFLPEIMARFTRS
CCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCC
NPRVELTVICEPTPGLVEHIKRGNLDLALVTHNDVRGQSEVVRREPLLWVTSANHATHEE
CCCEEEEEEECCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCEEEEECCCCCCCCC
ETLPMAFGRPNCIWRRAAVDVLDQQNRDYRILFTSFSATVITAAVLSGLAISVLPECALR
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHC
PGMRVLGEADGFGALPDCRIGIMRGQTSRPEIVDALARHISESLDNISVPLVEEAGTFDF
CCHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCHH
AALAYAKIRRTKANQILPGW
HHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PMKAPLDLDQLQTFISIADTGSFTRAAEEVHRTQSAVSMQMRRLEERIGKPLFEKEGRS
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCC
NRLTEEGDKLLSYARRLLYLNRETLAAFDDQRLEGTIRIGTPDDYADRFLPEIMARFTRS
CCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCC
NPRVELTVICEPTPGLVEHIKRGNLDLALVTHNDVRGQSEVVRREPLLWVTSANHATHEE
CCCEEEEEEECCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCEEEEECCCCCCCCC
ETLPMAFGRPNCIWRRAAVDVLDQQNRDYRILFTSFSATVITAAVLSGLAISVLPECALR
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHC
PGMRVLGEADGFGALPDCRIGIMRGQTSRPEIVDALARHISESLDNISVPLVEEAGTFDF
CCHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCHH
AALAYAKIRRTKANQILPGW
HHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]