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The map label for this gene is xseA

Identifier: 13475744

GI number: 13475744

Start: 5673842

End: 5675407

Strand: Reverse

Name: xseA

Synonym: mll6896

Alternate gene names: 13475744

Gene position: 5675407-5673842 (Counterclockwise)

Preceding gene: 13475745

Following gene: 13475743

Centisome position: 80.66

GC content: 68.9

Gene sequence:

>1566_bases
ATGAGCGAAGCAGCATCCGAATCACGCACCAACGCCACCGAATACACGGTGAGCGAGATTTCCGGCGCGCTGAAGCGCAC
GGTCGAGGACGTCTTCGGCAATGTGCGGGTGCGCGGCGAAATCTCGGGCTATCGCGGCCCGCATTCCTCCGGCCATGCCT
ATTTCGCACTGAAGGACGACCGCGCACGGCTCGATGCCGTGGTGTGGAAGGGCACGATGAGCCGGCTGAAATTCCGCCCC
GAGGAAGGGATGGAGGTGATCGCCACCGGCAAGCTCACCACCTACCCCGGCAAGTCCAACTACCAGATCGTCATCGACAA
TCTGGAGCCTGCCGGCGCAGGCGCGCTGATGGCGCTGCTGGAAGAGCGCAAGCGCCGGCTGCAGGCGGAGGGGCTTTTCG
ATGCCGGCCGCAAACGCCGGTTGCCGTTCATGCCGCGCACAATCGGCGTCGTCACCTCGCCGACCGGGTCGGTCATCCGC
GACATCATCCACCGCATCAAGGACCGCTTTCCGCTGCATGTGCTGGTCTGGCCGGTGCGCGTGCAGGGCGATACTGCGAG
TGCGGAAGTGACCAATGCCGTCACCGGCTTCAACGCGCTGGCCTGGGATGGCTCCATCCAGCGCCCCGATCTCCTGATCG
TGGCGCGCGGCGGCGGCAGCCTGGAGGATCTGTGGGGCTTCAACGACGAGGCGCTGGCCCGCGCCGTTGCGGCCTCCGGC
ATTCCGGTGATTTCCGCTGTCGGCCACGAGACCGACTGGACGCTGATCGACCTCGTCGCGGATGTGCGGGCGCCGACCCC
GACGGGCGCCGCCGAAATCGCGGTGCCGGTGAAGGCTGACCTCGAAGCGACGCTGGCCAGCCTTGGCGCGCGGCTCAAGG
CGGCGGTGTTGCGCAATTTCGAACGCAAGCGGCAGGCCGCCCGCGCGGCGGCGCGCGCCCTGCCCTCACCCGATCAATTG
CTGGCGCTGCCGCGCCGACGCCTCGACGAGGCGACATCCAGGCTCGGTCGTGGCCTGTCCGTCAGCGTCGATCGCAAGCG
GGCGCGTCTCCAGGGCCAGAGGCTGACGCCGGCTACGCTGTCGCGACGCATCAACGAGGCGCGCACGCTGACCGGGCGTG
ACCTCGCCCGCGCGCAGGCGGCGTTCTTTGCCATTGTGCGCGAACGGCGCGCACGCTTCGCGCGTACCGCGACGCGGCTG
TCGCCGGCGCCGATCGCACGCCGGCAGAAACTGCAGGCCGACACGCTGGCGGCGCTCGCCAGGCGGCAAGATCGGGTCAT
CTCGCTGCGGCTCGAACGCCTGCGCGGCCAGTTGAGCCAGGCCGAGCGCCTGCTGACCACGCTGTCGCACAAGGCCGTGC
TCGCGCGCGGCTTCGCGCTGGTGAAGAATGCCGACGGCGCCGTCATCAAGCAGGCGGCCGACGTGGTATCGGGGATGGCG
CTTACGCTGGAGTTCGCCGACGGCACGGCGGATGCGGTGGCGACCAGCGGTGCGGCGCGGCCAAAGCCGGCAGCCAAGCC
ATCAACAAAGGCCAAAGAACCCGGCAATCAGGGATCGCTGTTCTGA

Upstream 100 bases:

>100_bases
CGCCAAGATCAGGCGGACCAAGGCGAACCAGATCCTGCCGGGCTGGTAGGAAGGATCGTGGCGCCTTGACGCGGGGCGCC
AACCAGCCCCCAATCGGCCG

Downstream 100 bases:

>100_bases
CCATGACCGACAATCCGCACCATCTGGCGACGCCCAGCGGCAAACCGCGCGCGCGAAGCTTCGGCATCGGCTTCGACGGA
ACGCCCGGGCCGTTCAACGC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MSEAASESRTNATEYTVSEISGALKRTVEDVFGNVRVRGEISGYRGPHSSGHAYFALKDDRARLDAVVWKGTMSRLKFRP
EEGMEVIATGKLTTYPGKSNYQIVIDNLEPAGAGALMALLEERKRRLQAEGLFDAGRKRRLPFMPRTIGVVTSPTGSVIR
DIIHRIKDRFPLHVLVWPVRVQGDTASAEVTNAVTGFNALAWDGSIQRPDLLIVARGGGSLEDLWGFNDEALARAVAASG
IPVISAVGHETDWTLIDLVADVRAPTPTGAAEIAVPVKADLEATLASLGARLKAAVLRNFERKRQAARAAARALPSPDQL
LALPRRRLDEATSRLGRGLSVSVDRKRARLQGQRLTPATLSRRINEARTLTGRDLARAQAAFFAIVRERRARFARTATRL
SPAPIARRQKLQADTLAALARRQDRVISLRLERLRGQLSQAERLLTTLSHKAVLARGFALVKNADGAVIKQAADVVSGMA
LTLEFADGTADAVATSGAARPKPAAKPSTKAKEPGNQGSLF

Sequences:

>Translated_521_residues
MSEAASESRTNATEYTVSEISGALKRTVEDVFGNVRVRGEISGYRGPHSSGHAYFALKDDRARLDAVVWKGTMSRLKFRP
EEGMEVIATGKLTTYPGKSNYQIVIDNLEPAGAGALMALLEERKRRLQAEGLFDAGRKRRLPFMPRTIGVVTSPTGSVIR
DIIHRIKDRFPLHVLVWPVRVQGDTASAEVTNAVTGFNALAWDGSIQRPDLLIVARGGGSLEDLWGFNDEALARAVAASG
IPVISAVGHETDWTLIDLVADVRAPTPTGAAEIAVPVKADLEATLASLGARLKAAVLRNFERKRQAARAAARALPSPDQL
LALPRRRLDEATSRLGRGLSVSVDRKRARLQGQRLTPATLSRRINEARTLTGRDLARAQAAFFAIVRERRARFARTATRL
SPAPIARRQKLQADTLAALARRQDRVISLRLERLRGQLSQAERLLTTLSHKAVLARGFALVKNADGAVIKQAADVVSGMA
LTLEFADGTADAVATSGAARPKPAAKPSTKAKEPGNQGSLF
>Mature_520_residues
SEAASESRTNATEYTVSEISGALKRTVEDVFGNVRVRGEISGYRGPHSSGHAYFALKDDRARLDAVVWKGTMSRLKFRPE
EGMEVIATGKLTTYPGKSNYQIVIDNLEPAGAGALMALLEERKRRLQAEGLFDAGRKRRLPFMPRTIGVVTSPTGSVIRD
IIHRIKDRFPLHVLVWPVRVQGDTASAEVTNAVTGFNALAWDGSIQRPDLLIVARGGGSLEDLWGFNDEALARAVAASGI
PVISAVGHETDWTLIDLVADVRAPTPTGAAEIAVPVKADLEATLASLGARLKAAVLRNFERKRQAARAAARALPSPDQLL
ALPRRRLDEATSRLGRGLSVSVDRKRARLQGQRLTPATLSRRINEARTLTGRDLARAQAAFFAIVRERRARFARTATRLS
PAPIARRQKLQADTLAALARRQDRVISLRLERLRGQLSQAERLLTTLSHKAVLARGFALVKNADGAVIKQAADVVSGMAL
TLEFADGTADAVATSGAARPKPAAKPSTKAKEPGNQGSLF

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=485, Percent_Identity=34.8453608247423, Blast_Score=250, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_RHILO (Q987V3)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_107311.1
- GeneID:   1229966
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll6896
- NMPDR:   fig|266835.1.peg.5412
- HOGENOM:   HBG634411
- OMA:   LVWPVKV
- ProtClustDB:   PRK00286
- BRENDA:   3.1.11.6
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 56318; Mature: 56187

Theoretical pI: Translated: 11.45; Mature: 11.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAASESRTNATEYTVSEISGALKRTVEDVFGNVRVRGEISGYRGPHSSGHAYFALKDD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEEEECC
RARLDAVVWKGTMSRLKFRPEEGMEVIATGKLTTYPGKSNYQIVIDNLEPAGAGALMALL
CHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEECCCCCCCEEEEECCCCCCHHHHHHHH
EERKRRLQAEGLFDAGRKRRLPFMPRTIGVVTSPTGSVIRDIIHRIKDRFPLHVLVWPVR
HHHHHHHHHCCCHHCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCEEEEEEEEE
VQGDTASAEVTNAVTGFNALAWDGSIQRPDLLIVARGGGSLEDLWGFNDEALARAVAASG
ECCCCCCHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHCC
IPVISAVGHETDWTLIDLVADVRAPTPTGAAEIAVPVKADLEATLASLGARLKAAVLRNF
CCEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHH
ERKRQAARAAARALPSPDQLLALPRRRLDEATSRLGRGLSVSVDRKRARLQGQRLTPATL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCCCHHHH
SRRINEARTLTGRDLARAQAAFFAIVRERRARFARTATRLSPAPIARRQKLQADTLAALA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RRQDRVISLRLERLRGQLSQAERLLTTLSHKAVLARGFALVKNADGAVIKQAADVVSGMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCEE
LTLEFADGTADAVATSGAARPKPAAKPSTKAKEPGNQGSLF
EEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEAASESRTNATEYTVSEISGALKRTVEDVFGNVRVRGEISGYRGPHSSGHAYFALKDD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEEEECC
RARLDAVVWKGTMSRLKFRPEEGMEVIATGKLTTYPGKSNYQIVIDNLEPAGAGALMALL
CHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEECCCCCCCEEEEECCCCCCHHHHHHHH
EERKRRLQAEGLFDAGRKRRLPFMPRTIGVVTSPTGSVIRDIIHRIKDRFPLHVLVWPVR
HHHHHHHHHCCCHHCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCEEEEEEEEE
VQGDTASAEVTNAVTGFNALAWDGSIQRPDLLIVARGGGSLEDLWGFNDEALARAVAASG
ECCCCCCHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHCC
IPVISAVGHETDWTLIDLVADVRAPTPTGAAEIAVPVKADLEATLASLGARLKAAVLRNF
CCEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHH
ERKRQAARAAARALPSPDQLLALPRRRLDEATSRLGRGLSVSVDRKRARLQGQRLTPATL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCCCHHHH
SRRINEARTLTGRDLARAQAAFFAIVRERRARFARTATRLSPAPIARRQKLQADTLAALA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RRQDRVISLRLERLRGQLSQAERLLTTLSHKAVLARGFALVKNADGAVIKQAADVVSGMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCEE
LTLEFADGTADAVATSGAARPKPAAKPSTKAKEPGNQGSLF
EEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968