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The map label for this gene is blaSE [H]

Identifier: 13475731

GI number: 13475731

Start: 5659535

End: 5660350

Strand: Reverse

Name: blaSE [H]

Synonym: mll6878

Alternate gene names: 13475731

Gene position: 5660350-5659535 (Counterclockwise)

Preceding gene: 13475732

Following gene: 13475730

Centisome position: 80.45

GC content: 67.28

Gene sequence:

>816_bases
ATGATGCTGTTCTCGCCCGCGCCCTTCGAACTCGACCGGCTGGCGGACGAAGCCGACTATGCGGTGGTTGGGCCGACGGA
CGGGCGCGCCAGGGTCACCCACACCAACCGCTTTCCGCACAGTGCGGTCTGCCACATCGAGCGCGATTTCGGCGACGGCA
GGATGACCGGCTGTACCGCCTTCCTGATTTCGCCGACGCGACTGTTGACCGCGGCGCACTGCATCACCAGCCCGATCCGG
CAGCGGCTTGGCCTGCCCAATCTCGCCGTGCGCATTCGTGTCACGCCGGGTCGGGCCTCGCGTGACGCGCGGCCCTTTGG
CTGGCAGTGGGCCAAGCAATGGCACGTCAACCCGCCTTACCGCCGCCGTCCGTCAGGCCTGCACGATGTCGGGTTGATCG
AGCTCGAGCGGCCGTTTTCGCCATCGCCCGGGCACTTCCAGCTCTGGTCGCCGAACCGTCAGGACCTCGAGCGGCTTCGC
AACACGCGTCTGCTGCACATTTCGGGTTATCCGGCCGACAAGCCGGACGGGACGCAATGGGAGCATTCCGAGCGCCTGGA
CCGGATCACCGAACGGCAGCTTTTCTATAGCGTCGATACCTGTCCGGGACACAGCGGCGCTCCAGTCTGGATCCATCGCC
AACAGGCTGGCCCACCCGTGGTGATCGCGGTTCACACCGCCGGTCCACGTCCACATTCGGGTGGGGCCTGGGGATGCCGG
CCCGGCGTGCCGCTGGCCCCAGCGGGCCTGTTCAACCGAGGCGTCAGGCTGACCCCCGATCTCTTGCGTTCGATTCGCGC
CGGATTCAGGCGCTGA

Upstream 100 bases:

>100_bases
TGCAAGAGCCCGCGCATGAAGGTGGGATCGATGATGTACCGCAACAGGGTGTCATGCCCGCGGATGCCGCCTCACCGGGG
GCCGAACACGAGCAAGAGAC

Downstream 100 bases:

>100_bases
ACGGTGAAAAATTGACGACCCAACGATGATTTTTGCAATGCTAATATTTCGAAAAGTGCTATAGTCGAAGCTATCTATGC
AGCATTCATACTGGCCACCC

Product: glutamic acid specific endopeptidase

Products: NA

Alternate protein names: Glutamate-specific endopeptidase; GSE [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MMLFSPAPFELDRLADEADYAVVGPTDGRARVTHTNRFPHSAVCHIERDFGDGRMTGCTAFLISPTRLLTAAHCITSPIR
QRLGLPNLAVRIRVTPGRASRDARPFGWQWAKQWHVNPPYRRRPSGLHDVGLIELERPFSPSPGHFQLWSPNRQDLERLR
NTRLLHISGYPADKPDGTQWEHSERLDRITERQLFYSVDTCPGHSGAPVWIHRQQAGPPVVIAVHTAGPRPHSGGAWGCR
PGVPLAPAGLFNRGVRLTPDLLRSIRAGFRR

Sequences:

>Translated_271_residues
MMLFSPAPFELDRLADEADYAVVGPTDGRARVTHTNRFPHSAVCHIERDFGDGRMTGCTAFLISPTRLLTAAHCITSPIR
QRLGLPNLAVRIRVTPGRASRDARPFGWQWAKQWHVNPPYRRRPSGLHDVGLIELERPFSPSPGHFQLWSPNRQDLERLR
NTRLLHISGYPADKPDGTQWEHSERLDRITERQLFYSVDTCPGHSGAPVWIHRQQAGPPVVIAVHTAGPRPHSGGAWGCR
PGVPLAPAGLFNRGVRLTPDLLRSIRAGFRR
>Mature_271_residues
MMLFSPAPFELDRLADEADYAVVGPTDGRARVTHTNRFPHSAVCHIERDFGDGRMTGCTAFLISPTRLLTAAHCITSPIR
QRLGLPNLAVRIRVTPGRASRDARPFGWQWAKQWHVNPPYRRRPSGLHDVGLIELERPFSPSPGHFQLWSPNRQDLERLR
NTRLLHISGYPADKPDGTQWEHSERLDRITERQLFYSVDTCPGHSGAPVWIHRQQAGPPVVIAVHTAGPRPHSGGAWGCR
PGVPLAPAGLFNRGVRLTPDLLRSIRAGFRR

Specific function: Specific for hydrolysis of peptide bonds on the carboxyl side of acidic amino acid residues, with a strong preference for Glu [H]

COG id: COG3591

COG function: function code E; V8-like Glu-specific endopeptidase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009003
- InterPro:   IPR000126
- InterPro:   IPR001254
- InterPro:   IPR008256 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: =3.4.21.19 [H]

Molecular weight: Translated: 30386; Mature: 30386

Theoretical pI: Translated: 11.25; Mature: 11.25

Prosite motif: PS00134 TRYPSIN_HIS ; PS50240 TRYPSIN_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLFSPAPFELDRLADEADYAVVGPTDGRARVTHTNRFPHSAVCHIERDFGDGRMTGCTA
CCCCCCCCCHHHHHCCCCCEEEECCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCEEE
FLISPTRLLTAAHCITSPIRQRLGLPNLAVRIRVTPGRASRDARPFGWQWAKQWHVNPPY
EEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHCCCCCCCC
RRRPSGLHDVGLIELERPFSPSPGHFQLWSPNRQDLERLRNTRLLHISGYPADKPDGTQW
CCCCCCCCCCEEEEEECCCCCCCCCEEEECCCHHHHHHHHCCEEEEEECCCCCCCCCCCC
EHSERLDRITERQLFYSVDTCPGHSGAPVWIHRQQAGPPVVIAVHTAGPRPHSGGAWGCR
HHHHHHHHHHHHHHEEEEECCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCC
PGVPLAPAGLFNRGVRLTPDLLRSIRAGFRR
CCCCCCCCHHHHCCCEECHHHHHHHHHHHCC
>Mature Secondary Structure
MMLFSPAPFELDRLADEADYAVVGPTDGRARVTHTNRFPHSAVCHIERDFGDGRMTGCTA
CCCCCCCCCHHHHHCCCCCEEEECCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCEEE
FLISPTRLLTAAHCITSPIRQRLGLPNLAVRIRVTPGRASRDARPFGWQWAKQWHVNPPY
EEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHCCCCCCCC
RRRPSGLHDVGLIELERPFSPSPGHFQLWSPNRQDLERLRNTRLLHISGYPADKPDGTQW
CCCCCCCCCCEEEEEECCCCCCCCCEEEECCCHHHHHHHHCCEEEEEECCCCCCCCCCCC
EHSERLDRITERQLFYSVDTCPGHSGAPVWIHRQQAGPPVVIAVHTAGPRPHSGGAWGCR
HHHHHHHHHHHHHHEEEEECCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCC
PGVPLAPAGLFNRGVRLTPDLLRSIRAGFRR
CCCCCCCCHHHHCCCEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1429718; 1346764 [H]