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The map label for this gene is yfcX [C]

Identifier: 13475724

GI number: 13475724

Start: 5651436

End: 5652023

Strand: Reverse

Name: yfcX [C]

Synonym: mll6870

Alternate gene names: 13475724

Gene position: 5652023-5651436 (Counterclockwise)

Preceding gene: 13475725

Following gene: 13475723

Centisome position: 80.33

GC content: 62.07

Gene sequence:

>588_bases
ATGGTCGAGCATCATCAGGCTGACCGCAGCCCGGCCGAGTTCATGCATCTTTGCATGCGTTGGCATGAGGCATTCAACAA
GATGGAGTACGGCGGCGTCCCCGTCATCGCCGCACTGAAGGGCGCCGTCGTCGGCGGCGGTCTGGAGCTTGCAAGTGCTG
CCCATATCCGGGTGATGGACCAGACGACGTATTTTGCGCTGCCCGAGGGTCAACGCGGACTATTCACGGGCGGCGGTGCG
ACGATCCGCGTCGCCGACCTCGTCGGCAAGTCGCGCGTGATCGACATGATGCTGACAGGCCGTGTCTATCAGGGGCAGGA
GGCAGTCAATCTGGGACTTGCGCAATACATCACCGAAAGCTCCAGCCTTGAAAGGGCGATGGAACTGGCTCGCAAGGCGG
CTCAGAACTTGCCCCTTTCGAACTTTGCCATCTGCTCAGCCGTCAGCCATATGCAGAACATGTCGGCGCTGGATGCAGCC
TATGCCGAGGCGGTGGTGGCGGGCGTGGTGAACACCCAGCCTGACGCCCGCGCCCGTCTTGCGGCCTTTGCCGACAAATC
GGCGGCCAGGGTACGACCTAACAGTTGA

Upstream 100 bases:

>100_bases
CCAGAAGGCTGCGGAGGCAATTGAGACGCGCATGAAAGCCATGGGATTCAGATCGCGCCAAGTCACTATCTCCCATAGTC
TGTGGCGTAGGCAACTTCCA

Downstream 100 bases:

>100_bases
TGAGGCTGCGCCGATGTTATCGCCAAAAGAACAGGACTGGCGCTGAACCGGCAGCGTCCAGACTGTGAAGTGGACTGTGT
CCCTCTGGCTTCACCTCGGT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MVEHHQADRSPAEFMHLCMRWHEAFNKMEYGGVPVIAALKGAVVGGGLELASAAHIRVMDQTTYFALPEGQRGLFTGGGA
TIRVADLVGKSRVIDMMLTGRVYQGQEAVNLGLAQYITESSSLERAMELARKAAQNLPLSNFAICSAVSHMQNMSALDAA
YAEAVVAGVVNTQPDARARLAAFADKSAARVRPNS

Sequences:

>Translated_195_residues
MVEHHQADRSPAEFMHLCMRWHEAFNKMEYGGVPVIAALKGAVVGGGLELASAAHIRVMDQTTYFALPEGQRGLFTGGGA
TIRVADLVGKSRVIDMMLTGRVYQGQEAVNLGLAQYITESSSLERAMELARKAAQNLPLSNFAICSAVSHMQNMSALDAA
YAEAVVAGVVNTQPDARARLAAFADKSAARVRPNS
>Mature_195_residues
MVEHHQADRSPAEFMHLCMRWHEAFNKMEYGGVPVIAALKGAVVGGGLELASAAHIRVMDQTTYFALPEGQRGLFTGGGA
TIRVADLVGKSRVIDMMLTGRVYQGQEAVNLGLAQYITESSSLERAMELARKAAQNLPLSNFAICSAVSHMQNMSALDAA
YAEAVVAGVVNTQPDARARLAAFADKSAARVRPNS

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI68989263, Length=133, Percent_Identity=30.8270676691729, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI20127408, Length=115, Percent_Identity=33.0434782608696, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788682, Length=113, Percent_Identity=44.2477876106195, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI221142681, Length=191, Percent_Identity=30.8900523560209, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1787659, Length=142, Percent_Identity=36.6197183098592, Blast_Score=67, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=119, Percent_Identity=34.453781512605, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17558304, Length=120, Percent_Identity=30, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=133, Percent_Identity=34.5864661654135, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=133, Percent_Identity=34.5864661654135, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=128, Percent_Identity=34.375, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560910, Length=99, Percent_Identity=37.3737373737374, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24653139, Length=183, Percent_Identity=30.0546448087432, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI20129971, Length=90, Percent_Identity=40, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24653477, Length=90, Percent_Identity=40, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 20862; Mature: 20862

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEHHQADRSPAEFMHLCMRWHEAFNKMEYGGVPVIAALKGAVVGGGLELASAAHIRVMD
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHCCEEEEEEE
QTTYFALPEGQRGLFTGGGATIRVADLVGKSRVIDMMLTGRVYQGQEAVNLGLAQYITES
CCEEEECCCCCCCEEECCCCEEEHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCH
SSLERAMELARKAAQNLPLSNFAICSAVSHMQNMSALDAAYAEAVVAGVVNTQPDARARL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AAFADKSAARVRPNS
HHHHCCCCCCCCCCC
>Mature Secondary Structure
MVEHHQADRSPAEFMHLCMRWHEAFNKMEYGGVPVIAALKGAVVGGGLELASAAHIRVMD
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHCCEEEEEEE
QTTYFALPEGQRGLFTGGGATIRVADLVGKSRVIDMMLTGRVYQGQEAVNLGLAQYITES
CCEEEECCCCCCCEEECCCCEEEHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCH
SSLERAMELARKAAQNLPLSNFAICSAVSHMQNMSALDAAYAEAVVAGVVNTQPDARARL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AAFADKSAARVRPNS
HHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA