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The map label for this gene is dapA [H]

Identifier: 13475681

GI number: 13475681

Start: 5604505

End: 5605467

Strand: Reverse

Name: dapA [H]

Synonym: mll6811

Alternate gene names: 13475681

Gene position: 5605467-5604505 (Counterclockwise)

Preceding gene: 13475692

Following gene: 13475673

Centisome position: 79.67

GC content: 65.11

Gene sequence:

>963_bases
ATGACTGCTAATGTTTTTTCCGGCTGCATGCCGGCGTTGATGACCCCATGCACGCAGGACCGTCAGCCCGACTTCGACGC
GCTGGTACGCAAGGGACGAGAGCTGATAGCCGCCGGCATGTCGGCCGTCGTCTATTGCGGCTCGATGGGCGACTGGCCGC
TCCTGACCGACGAGCAACGCATGGAAGGCGTCGAGCGCCTGGTGAAGGCCGGCGTGCCGGTGATCGTCGGCACCGGCGCG
GTCAACACCGCCAAGGCCGTGGCGCACGCGGCGCATGCCCAGAAGGTCGGCGCGCGAGGCCTGATGGTGATCCCGCGTGT
TTTGTCGCGCGGGCCTTCGGTGACGGCGCAGCGCCATCATTTCAAGGCAATTCTTGCCGCCGCGCCCGGCCTGCCGGCGG
TCATCTACAACAGCCCCTATTACGGCTTTGCCACGCGTGCGGACCTGTTCTTCGCGCTACGCGCCGAACATCCGAACCTG
GTCGGCTTCAAGGAGTTCGGCGGCCCGTCGGACCTGCGCTACGCGGCGGAAAACATCACCAGCCGCGACGATGAGGTCGC
GCTGATGATCGGCGTCGACACCGCCGTCTTCCACGGTTTCGTCAATTGCGGCGCGTCCGGCGCCATCACCGGCATCGGCA
ACGTGCTGCCAAAGGAGGTGCTGCACCTTGTGGGCTTGAGCCAGGCGGCGGCCAAGGGCGACGTCGAAGCCCGCCAGCGC
GCGCTGGAGCTCGACGCTGCGCTCGCCGTGCTGTCCTCCTTCGACGAAGGCCCAGACCTGGTGCTCTATTTCAAGCACAT
GATGGTGCTGAAGGGTAATCCCGAGTACAAGCTGCACTTCAACGAGACCGATGCCTTGACCGACAGCCAGCGCGGCTACG
CCGAGGCGCAGCTCAAATTGTTCGACAGCTGGTATGCCCAATGGTCGAGGCAACCCGGCGTGATTGCAAGGTCTGCAGCC
TGA

Upstream 100 bases:

>100_bases
CTGCGTTGGTCCCTCGCGGCCACGACTATTTTGCTTGGCAAGCCGTGCCGCTTCGGGACAAACTGATCAATCCGCGTGCA
AGCCTCAAGGAGAATCCGAA

Downstream 100 bases:

>100_bases
GCCCGGCAAGTGCGACGGGCGGCCATAGTACGGCCGCCGGTTGCATTGCGAGGCTGAGCAGCCACTATCCGACTTAGTGC
CTGACCATCCCGGCGTCGAC

Product: dihydroxydipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTANVFSGCMPALMTPCTQDRQPDFDALVRKGRELIAAGMSAVVYCGSMGDWPLLTDEQRMEGVERLVKAGVPVIVGTGA
VNTAKAVAHAAHAQKVGARGLMVIPRVLSRGPSVTAQRHHFKAILAAAPGLPAVIYNSPYYGFATRADLFFALRAEHPNL
VGFKEFGGPSDLRYAAENITSRDDEVALMIGVDTAVFHGFVNCGASGAITGIGNVLPKEVLHLVGLSQAAAKGDVEARQR
ALELDAALAVLSSFDEGPDLVLYFKHMMVLKGNPEYKLHFNETDALTDSQRGYAEAQLKLFDSWYAQWSRQPGVIARSAA

Sequences:

>Translated_320_residues
MTANVFSGCMPALMTPCTQDRQPDFDALVRKGRELIAAGMSAVVYCGSMGDWPLLTDEQRMEGVERLVKAGVPVIVGTGA
VNTAKAVAHAAHAQKVGARGLMVIPRVLSRGPSVTAQRHHFKAILAAAPGLPAVIYNSPYYGFATRADLFFALRAEHPNL
VGFKEFGGPSDLRYAAENITSRDDEVALMIGVDTAVFHGFVNCGASGAITGIGNVLPKEVLHLVGLSQAAAKGDVEARQR
ALELDAALAVLSSFDEGPDLVLYFKHMMVLKGNPEYKLHFNETDALTDSQRGYAEAQLKLFDSWYAQWSRQPGVIARSAA
>Mature_319_residues
TANVFSGCMPALMTPCTQDRQPDFDALVRKGRELIAAGMSAVVYCGSMGDWPLLTDEQRMEGVERLVKAGVPVIVGTGAV
NTAKAVAHAAHAQKVGARGLMVIPRVLSRGPSVTAQRHHFKAILAAAPGLPAVIYNSPYYGFATRADLFFALRAEHPNLV
GFKEFGGPSDLRYAAENITSRDDEVALMIGVDTAVFHGFVNCGASGAITGIGNVLPKEVLHLVGLSQAAAKGDVEARQRA
LELDAALAVLSSFDEGPDLVLYFKHMMVLKGNPEYKLHFNETDALTDSQRGYAEAQLKLFDSWYAQWSRQPGVIARSAA

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=250, Percent_Identity=28, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1786463, Length=237, Percent_Identity=27.8481012658228, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082415, Length=259, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788823, Length=256, Percent_Identity=28.90625, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789620, Length=243, Percent_Identity=28.3950617283951, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 34331; Mature: 34200

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTANVFSGCMPALMTPCTQDRQPDFDALVRKGRELIAAGMSAVVYCGSMGDWPLLTDEQR
CCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHH
MEGVERLVKAGVPVIVGTGAVNTAKAVAHAAHAQKVGARGLMVIPRVLSRGPSVTAQRHH
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHH
FKAILAAAPGLPAVIYNSPYYGFATRADLFFALRAEHPNLVGFKEFGGPSDLRYAAENIT
HHHHHHHCCCCCEEEECCCCCCCCHHHHEEEEEECCCCCEEEEHHCCCCHHHHHHHHHCC
SRDDEVALMIGVDTAVFHGFVNCGASGAITGIGNVLPKEVLHLVGLSQAAAKGDVEARQR
CCCCCEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHH
ALELDAALAVLSSFDEGPDLVLYFKHMMVLKGNPEYKLHFNETDALTDSQRGYAEAQLKL
HHHHHHHHHHHHHCCCCCCEEEEEEEHHEEECCCCEEEEECCCCCCCCCCCCHHHHHHHH
FDSWYAQWSRQPGVIARSAA
HHHHHHHHCCCCCCEECCCC
>Mature Secondary Structure 
TANVFSGCMPALMTPCTQDRQPDFDALVRKGRELIAAGMSAVVYCGSMGDWPLLTDEQR
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHH
MEGVERLVKAGVPVIVGTGAVNTAKAVAHAAHAQKVGARGLMVIPRVLSRGPSVTAQRHH
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHH
FKAILAAAPGLPAVIYNSPYYGFATRADLFFALRAEHPNLVGFKEFGGPSDLRYAAENIT
HHHHHHHCCCCCEEEECCCCCCCCHHHHEEEEEECCCCCEEEEHHCCCCHHHHHHHHHCC
SRDDEVALMIGVDTAVFHGFVNCGASGAITGIGNVLPKEVLHLVGLSQAAAKGDVEARQR
CCCCCEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHH
ALELDAALAVLSSFDEGPDLVLYFKHMMVLKGNPEYKLHFNETDALTDSQRGYAEAQLKL
HHHHHHHHHHHHHCCCCCCEEEEEEEHHEEECCCCEEEEECCCCCCCCCCCCHHHHHHHH
FDSWYAQWSRQPGVIARSAA
HHHHHHHHCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA