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The map label for this gene is glmS [H]

Identifier: 13475654

GI number: 13475654

Start: 5576813

End: 5578636

Strand: Direct

Name: glmS [H]

Synonym: mlr6774

Alternate gene names: 13475654

Gene position: 5576813-5578636 (Clockwise)

Preceding gene: 13475652

Following gene: 13475657

Centisome position: 79.26

GC content: 63.71

Gene sequence:

>1824_bases
ATGTGCGGCATCGTCGGAATCGTCGGCCACTCGCAGGTTACGTCGCTCATCCTCACCACGCTGAAGCGGCTCGAATATCG
CGGTTATGACTCGGCCGGCGTCGCCACCATCGAGCATGGCGAGCTCGCCCGCCGTCGCGCCGAAGGCAAGCTGATCAACC
TCGAGCGCCGGCTCAAGGAGGAGCCGCTCGACGGCACGATCGGCATCGGCCACACACGCTGGGCCACCCATGGCGTGCCC
AACGAGACCAACGCGCATCCGCATTTTTCCGACGGCGTCGCCATCGTCCACAACGGCATCATCGAGAACTTTGCCGAGCT
GCGCGACGAGCTGGTCCGCGACGGCTATGCCTTCTCCTCGCAGACCGATACAGAGGTCGTGGCGCATCTGGTGGCGCGCG
AGTTGGCCAAGGGGCTGAAGCCGGTCGAGGCCGCGCATCAGGCGCTGAAGCGGCTGGAAGGCGCCTTTGCGCTGGCCATC
ATGTTCAAGGGCGACGAGGACCTGATCGTCGGCGCCCGCAACGGCCCGCCACTGGCCGTCGGCCATGGCGATGGCGAGAT
GTTCTTGGGCTCGGACGCCATCGCGCTGGCGCCATTCACCAATTCGATCACCTATCTCGAGGACGGCGACTGGGCGGTGG
TGCGCCGCGACAGCGTCGCCATCTTCGACATCGACGGCAAAAAGGTCGAGCGCAAGCGCCAGCAGTCGCTGTCGACCTCC
TTCATGGTCGACAAGGGCAACCGCCGCCATTTCATGGAGAAGGAAATCCATGAACAGCCCGAGGTGATCTCGCACACGCT
GGCGCATTATGTCGATTTCGTCTCCGGCGTTTCGAAGCCGCTCGACCTGCCGTTCGACTTCGCCAAGATCGGCCGGCTGG
CGATTTCGGCTTGCGGCACCGCCTATCTCGCCGGCCTGATCGGCAAATACTGGTTCGAGCGCTATGCGCGGCTGCCGGTC
GACATCGATGTCGCCTCGGAGTTCCGCTACCGCGAAATGCCGCTGTCGGCCAATGATGCCGCCTTCTTCATCTCGCAGTC
GGGCGAGACCGCCGACACGCTGGCCTCGCTGCGTTATTGCCGCAAGGCCGGCATGAAGATCGGCGCCGTCGTCAATGTTC
GGGAATCGACCATGGCGCGCGAATCCGACGTCGTGCTGCCGACGCTCGCCGGCCCCGAGATCGGCGTTGCCTCGACCAAG
GCTTTCACTTGCCAGCTGTCGGTGCTGGCCTCGCTTGCGGTGCGCGCCGGCGTGGCGCGCGGGGTGATTTCGCAGGAGCA
GGAAAAGACCCTGGTGCGCGCGCTTTCGGAAGCGCCGCGCTATGCCAACCAGGTGCTCAAGCTCGAAGAGCAGATCGAGC
GGATCGCGCGCGAACTGTCGCGCTACAAGGACGTGCTCTATCTCGGCCGCGACACCAATTTCCCGCTGGCCATGGAAGGC
GCGCTGAAACTCAAGGAAATCTCCTATATCCACGCCGAGGGCTATGCGGCGGGCGAATTGAAGCATGGGCCGATCGCACT
GATCGACGAGAACATGCCGGTCATCGTCATTGCGCCGCATGACCGCATTTTCGAGAAGACCGTGTCGAACATGCAGGAAG
TGGCGGCGCGTGGCGGCAAGATCATCCTGATCACCGACAGCAAAGGGGCGGCGCAGGTGAGCGTCAAGACGATGGAGACG
ATCATCCTGCCGGACGTGCCGGAAATCATCTCGCCGATCATCTATGCGCTGCCGATCCAGATGTTGGCCTATTTCGCCGC
CGTGTTCATGGGCACCGATGTCGACCAGCCGCGCAATCTGGCGAAATCCGTGACGGTGGAGTGA

Upstream 100 bases:

>100_bases
CCCAGGCTCCTTCAAATGAACGATCAGCCCGTTATCAAGGAGGGATATCGTGGCCTCTACGGTGACAAGGCCGGTATTCT
GCAGGTCAGGGGGCAAAGCC

Downstream 100 bases:

>100_bases
CGGTAAGGTCGACGGCCCTTCATCTCGTCGGAGAGACGATCGACAAGACCCGCGGTCACTATCAATGCCTGCGGGATCGC
TCGCGGCATCCCATCGGTTT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MCGIVGIVGHSQVTSLILTTLKRLEYRGYDSAGVATIEHGELARRRAEGKLINLERRLKEEPLDGTIGIGHTRWATHGVP
NETNAHPHFSDGVAIVHNGIIENFAELRDELVRDGYAFSSQTDTEVVAHLVARELAKGLKPVEAAHQALKRLEGAFALAI
MFKGDEDLIVGARNGPPLAVGHGDGEMFLGSDAIALAPFTNSITYLEDGDWAVVRRDSVAIFDIDGKKVERKRQQSLSTS
FMVDKGNRRHFMEKEIHEQPEVISHTLAHYVDFVSGVSKPLDLPFDFAKIGRLAISACGTAYLAGLIGKYWFERYARLPV
DIDVASEFRYREMPLSANDAAFFISQSGETADTLASLRYCRKAGMKIGAVVNVRESTMARESDVVLPTLAGPEIGVASTK
AFTCQLSVLASLAVRAGVARGVISQEQEKTLVRALSEAPRYANQVLKLEEQIERIARELSRYKDVLYLGRDTNFPLAMEG
ALKLKEISYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRIFEKTVSNMQEVAARGGKIILITDSKGAAQVSVKTMET
IILPDVPEIISPIIYALPIQMLAYFAAVFMGTDVDQPRNLAKSVTVE

Sequences:

>Translated_607_residues
MCGIVGIVGHSQVTSLILTTLKRLEYRGYDSAGVATIEHGELARRRAEGKLINLERRLKEEPLDGTIGIGHTRWATHGVP
NETNAHPHFSDGVAIVHNGIIENFAELRDELVRDGYAFSSQTDTEVVAHLVARELAKGLKPVEAAHQALKRLEGAFALAI
MFKGDEDLIVGARNGPPLAVGHGDGEMFLGSDAIALAPFTNSITYLEDGDWAVVRRDSVAIFDIDGKKVERKRQQSLSTS
FMVDKGNRRHFMEKEIHEQPEVISHTLAHYVDFVSGVSKPLDLPFDFAKIGRLAISACGTAYLAGLIGKYWFERYARLPV
DIDVASEFRYREMPLSANDAAFFISQSGETADTLASLRYCRKAGMKIGAVVNVRESTMARESDVVLPTLAGPEIGVASTK
AFTCQLSVLASLAVRAGVARGVISQEQEKTLVRALSEAPRYANQVLKLEEQIERIARELSRYKDVLYLGRDTNFPLAMEG
ALKLKEISYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRIFEKTVSNMQEVAARGGKIILITDSKGAAQVSVKTMET
IILPDVPEIISPIIYALPIQMLAYFAAVFMGTDVDQPRNLAKSVTVE
>Mature_607_residues
MCGIVGIVGHSQVTSLILTTLKRLEYRGYDSAGVATIEHGELARRRAEGKLINLERRLKEEPLDGTIGIGHTRWATHGVP
NETNAHPHFSDGVAIVHNGIIENFAELRDELVRDGYAFSSQTDTEVVAHLVARELAKGLKPVEAAHQALKRLEGAFALAI
MFKGDEDLIVGARNGPPLAVGHGDGEMFLGSDAIALAPFTNSITYLEDGDWAVVRRDSVAIFDIDGKKVERKRQQSLSTS
FMVDKGNRRHFMEKEIHEQPEVISHTLAHYVDFVSGVSKPLDLPFDFAKIGRLAISACGTAYLAGLIGKYWFERYARLPV
DIDVASEFRYREMPLSANDAAFFISQSGETADTLASLRYCRKAGMKIGAVVNVRESTMARESDVVLPTLAGPEIGVASTK
AFTCQLSVLASLAVRAGVARGVISQEQEKTLVRALSEAPRYANQVLKLEEQIERIARELSRYKDVLYLGRDTNFPLAMEG
ALKLKEISYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRIFEKTVSNMQEVAARGGKIILITDSKGAAQVSVKTMET
IILPDVPEIISPIIYALPIQMLAYFAAVFMGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=695, Percent_Identity=36.4028776978417, Blast_Score=391, Evalue=1e-109,
Organism=Homo sapiens, GI205277386, Length=687, Percent_Identity=35.8078602620087, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI29570798, Length=201, Percent_Identity=27.363184079602, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1790167, Length=611, Percent_Identity=48.772504091653, Blast_Score=556, Evalue=1e-159,
Organism=Escherichia coli, GI1788651, Length=214, Percent_Identity=32.7102803738318, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17539970, Length=713, Percent_Identity=34.6423562412342, Blast_Score=366, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17532899, Length=716, Percent_Identity=34.0782122905028, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17532897, Length=431, Percent_Identity=38.5150812064965, Blast_Score=284, Evalue=9e-77,
Organism=Saccharomyces cerevisiae, GI6322745, Length=450, Percent_Identity=38, Blast_Score=273, Evalue=5e-74,
Organism=Saccharomyces cerevisiae, GI6323731, Length=433, Percent_Identity=30.4849884526559, Blast_Score=191, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6323730, Length=207, Percent_Identity=34.2995169082126, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323958, Length=167, Percent_Identity=28.7425149700599, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357745, Length=690, Percent_Identity=37.6811594202899, Blast_Score=412, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 66490; Mature: 66490

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGIVGHSQVTSLILTTLKRLEYRGYDSAGVATIEHGELARRRAEGKLINLERRLKE
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHCCCEEEHHHHHHC
EPLDGTIGIGHTRWATHGVPNETNAHPHFSDGVAIVHNGIIENFAELRDELVRDGYAFSS
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QTDTEVVAHLVARELAKGLKPVEAAHQALKRLEGAFALAIMFKGDEDLIVGARNGPPLAV
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCCEEE
GHGDGEMFLGSDAIALAPFTNSITYLEDGDWAVVRRDSVAIFDIDGKKVERKRQQSLSTS
ECCCCCEEECCCCEEEECCCCCEEEEECCCEEEEEECCEEEEECCCHHHHHHHHHHCCCE
FMVDKGNRRHFMEKEIHEQPEVISHTLAHYVDFVSGVSKPLDLPFDFAKIGRLAISACGT
EEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AYLAGLIGKYWFERYARLPVDIDVASEFRYREMPLSANDAAFFISQSGETADTLASLRYC
HHHHHHHHHHHHHHHHCCCCEEEHHCCCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHH
RKAGMKIGAVVNVRESTMARESDVVLPTLAGPEIGVASTKAFTCQLSVLASLAVRAGVAR
HHCCCEEEEEEEEHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GVISQEQEKTLVRALSEAPRYANQVLKLEEQIERIARELSRYKDVLYLGRDTNFPLAMEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEECC
ALKLKEISYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRIFEKTVSNMQEVAARGGK
CEEEHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCE
IILITDSKGAAQVSVKTMETIILPDVPEIISPIIYALPIQMLAYFAAVFMGTDVDQPRNL
EEEEECCCCCCEEEHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AKSVTVE
HHHCCCC
>Mature Secondary Structure
MCGIVGIVGHSQVTSLILTTLKRLEYRGYDSAGVATIEHGELARRRAEGKLINLERRLKE
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHCCCEEEHHHHHHC
EPLDGTIGIGHTRWATHGVPNETNAHPHFSDGVAIVHNGIIENFAELRDELVRDGYAFSS
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QTDTEVVAHLVARELAKGLKPVEAAHQALKRLEGAFALAIMFKGDEDLIVGARNGPPLAV
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCCEEE
GHGDGEMFLGSDAIALAPFTNSITYLEDGDWAVVRRDSVAIFDIDGKKVERKRQQSLSTS
ECCCCCEEECCCCEEEECCCCCEEEEECCCEEEEEECCEEEEECCCHHHHHHHHHHCCCE
FMVDKGNRRHFMEKEIHEQPEVISHTLAHYVDFVSGVSKPLDLPFDFAKIGRLAISACGT
EEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AYLAGLIGKYWFERYARLPVDIDVASEFRYREMPLSANDAAFFISQSGETADTLASLRYC
HHHHHHHHHHHHHHHHCCCCEEEHHCCCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHH
RKAGMKIGAVVNVRESTMARESDVVLPTLAGPEIGVASTKAFTCQLSVLASLAVRAGVAR
HHCCCEEEEEEEEHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GVISQEQEKTLVRALSEAPRYANQVLKLEEQIERIARELSRYKDVLYLGRDTNFPLAMEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEECC
ALKLKEISYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRIFEKTVSNMQEVAARGGK
CEEEHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCE
IILITDSKGAAQVSVKTMETIILPDVPEIISPIIYALPIQMLAYFAAVFMGTDVDQPRNL
EEEEECCCCCCEEEHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AKSVTVE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]