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The map label for this gene is puuP [H]

Identifier: 13475604

GI number: 13475604

Start: 5509171

End: 5510697

Strand: Reverse

Name: puuP [H]

Synonym: mll6718

Alternate gene names: 13475604

Gene position: 5510697-5509171 (Counterclockwise)

Preceding gene: 13475605

Following gene: 13475603

Centisome position: 78.32

GC content: 61.3

Gene sequence:

>1527_bases
ATGGCCATAGAAACTGCACGCGGGACGATCGACGTCTCGAAAAGTAACAGCATCAATCTTTTGCACTCCAAGGCCGTGGG
GCTCGCCGGAGTGCTCTTCCTGGCCGTCACCGGCGCGGCGCCAATGTCGGCGATGCTGGGCAATGTCCCGTTCGCGGCAG
GCTACGGCATCGGCAAATACACGCCGGCAGCCTTCCTGATGGCGACGATTGTGCTGACCATCTTCTCGATCGGCTATGCC
GCGATGGCATCGCGCGTATCGTCGGTCGGCGGCTTCTACTCCTTCATCAGCCAGGGGCTCGGCCGCGAGGTCGGCATGTC
GGCGGGCATCGGCTCGCTCGCCTGCTATTCGCTGTTCGAAGCTTCCCTCACCGGACTGTTCGCCTTTTTCGGCAATCTGT
GGCTTTCCCAGCATTTCGGCATCAACGTGCCGTGGATCGTGCTGGCGCTCGCCATGATCGTGGTCATCGCAGCGCTTGCC
TACCGCGACGTGAAAGTGTCGGCACGGCTGCTCGGCATAGCCCTCATTCTTGAAGTGATCATGCTGGTGATCTTTTCGCT
GGGCGTGATTTTTGCCCATGGCGGGACGAATTTTTCCGGCGATTCGCTCAATGTGTTCAAGGTGTTCACGCCTGTAGCCG
AGCAGAAGGTCGGCGATGTCGCCATACCGGCGGGCGAAGCGGCCGTCGGCATCTTCATGGCGTTCTGGTCGTGGGTCGGC
TTCGAGATGGCGCCGAACTATGCCGAGGAATCCCGCGATCCGAAGCGCATCATTCCGCAATCGCTGCTGATTTCGGTCAT
TGGCCTTGGCCTGTTCTACACCTTCGTCAGCTGGTGCGCGGTGGCGGCCTATCCGACCGAGGCCGATATGGTAGCCAAGG
CCTTCTCCGACGGCGTGAACTTCTTCCTGACACCGGTGCAGAGTTTTGTCGGCGGCTGGGGCTACCAGCTGATGTCGCTG
CTCATCCTGACCAGTTCCTTCGCCTGCGGCATGGCCTTCCACAACACCGCTTCCCGCTATTTGTATTCGCTGGCGCGCGA
AGGCGTCCTGCCGCAGGCGATCGCCGAGACGCATGACCACCACAAGAGCCCACACAAGGCCTCGGCGCTGCAGTCGGTGC
TGGCGGCGGTATGGGTGCTGCTCTACGGTCTGGCCTACGGCTTCGACGATCCGTCGGGACAGGCCTGGCTGGGCGTCTAT
ACGCTGTTTGCCGTGCTTGGCACCGGACTGCTTTTGGTGCTGCAGGCCGTTGTCTCGCTGGCCATCTACATGTGGTTCAA
GAAGAACGGCGGCGGCAGCATGCTGACGACTGTCATCGCGCCGTTGATCTCGCTGGTTGTGCAGTTGGTCCTCGTCTACA
CGCTGGTCGCCAATCTGGCGACCCTGGGCGGCACCAATGGTTTCGCCAGGAGCATCCCCTATGTCGGGCTTGCGATCCTT
ATCGTCGGCCTGATCTGGGGCTTCGTGCTGAAGTCGGCCAACCCCAAGGCGTATGAGAACATCGGTCACATGGTGAACGA
GGGCTAG

Upstream 100 bases:

>100_bases
ACGCTGCGTCCGTAGTGTCGTGGCTGCACGAGCAGGCTGGGACACATCGGCCGCCCTGTGCGGGGAACTGCAGACAGCTG
TCACGAATGGAGAGGGCTTC

Downstream 100 bases:

>100_bases
GGCATTCCTCGCCCTGGATTTTCTTGCCTCACGGGGACGGAGCATCACTCTGTCCCCGTCTCATTTTGGAGCTTCAAGTC
ATGACCCAGTCTTTGAAGGG

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MAIETARGTIDVSKSNSINLLHSKAVGLAGVLFLAVTGAAPMSAMLGNVPFAAGYGIGKYTPAAFLMATIVLTIFSIGYA
AMASRVSSVGGFYSFISQGLGREVGMSAGIGSLACYSLFEASLTGLFAFFGNLWLSQHFGINVPWIVLALAMIVVIAALA
YRDVKVSARLLGIALILEVIMLVIFSLGVIFAHGGTNFSGDSLNVFKVFTPVAEQKVGDVAIPAGEAAVGIFMAFWSWVG
FEMAPNYAEESRDPKRIIPQSLLISVIGLGLFYTFVSWCAVAAYPTEADMVAKAFSDGVNFFLTPVQSFVGGWGYQLMSL
LILTSSFACGMAFHNTASRYLYSLAREGVLPQAIAETHDHHKSPHKASALQSVLAAVWVLLYGLAYGFDDPSGQAWLGVY
TLFAVLGTGLLLVLQAVVSLAIYMWFKKNGGGSMLTTVIAPLISLVVQLVLVYTLVANLATLGGTNGFARSIPYVGLAIL
IVGLIWGFVLKSANPKAYENIGHMVNEG

Sequences:

>Translated_508_residues
MAIETARGTIDVSKSNSINLLHSKAVGLAGVLFLAVTGAAPMSAMLGNVPFAAGYGIGKYTPAAFLMATIVLTIFSIGYA
AMASRVSSVGGFYSFISQGLGREVGMSAGIGSLACYSLFEASLTGLFAFFGNLWLSQHFGINVPWIVLALAMIVVIAALA
YRDVKVSARLLGIALILEVIMLVIFSLGVIFAHGGTNFSGDSLNVFKVFTPVAEQKVGDVAIPAGEAAVGIFMAFWSWVG
FEMAPNYAEESRDPKRIIPQSLLISVIGLGLFYTFVSWCAVAAYPTEADMVAKAFSDGVNFFLTPVQSFVGGWGYQLMSL
LILTSSFACGMAFHNTASRYLYSLAREGVLPQAIAETHDHHKSPHKASALQSVLAAVWVLLYGLAYGFDDPSGQAWLGVY
TLFAVLGTGLLLVLQAVVSLAIYMWFKKNGGGSMLTTVIAPLISLVVQLVLVYTLVANLATLGGTNGFARSIPYVGLAIL
IVGLIWGFVLKSANPKAYENIGHMVNEG
>Mature_507_residues
AIETARGTIDVSKSNSINLLHSKAVGLAGVLFLAVTGAAPMSAMLGNVPFAAGYGIGKYTPAAFLMATIVLTIFSIGYAA
MASRVSSVGGFYSFISQGLGREVGMSAGIGSLACYSLFEASLTGLFAFFGNLWLSQHFGINVPWIVLALAMIVVIAALAY
RDVKVSARLLGIALILEVIMLVIFSLGVIFAHGGTNFSGDSLNVFKVFTPVAEQKVGDVAIPAGEAAVGIFMAFWSWVGF
EMAPNYAEESRDPKRIIPQSLLISVIGLGLFYTFVSWCAVAAYPTEADMVAKAFSDGVNFFLTPVQSFVGGWGYQLMSLL
ILTSSFACGMAFHNTASRYLYSLAREGVLPQAIAETHDHHKSPHKASALQSVLAAVWVLLYGLAYGFDDPSGQAWLGVYT
LFAVLGTGLLLVLQAVVSLAIYMWFKKNGGGSMLTTVIAPLISLVVQLVLVYTLVANLATLGGTNGFARSIPYVGLAILI
VGLIWGFVLKSANPKAYENIGHMVNEG

Specific function: Imports putrescine [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081869, Length=307, Percent_Identity=22.4755700325733, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87082023, Length=356, Percent_Identity=23.314606741573, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24668806, Length=400, Percent_Identity=24.25, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356285, Length=400, Percent_Identity=24.25, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24668802, Length=400, Percent_Identity=24.25, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53821; Mature: 53690

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AIETARGTIDVSKSNSINLLHSKAVGLAGVLFLAVTGAAPMSAMLGNVPFAAGYGIGKY
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCC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HHHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]