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The map label for this gene is ygjG [C]

Identifier: 13475601

GI number: 13475601

Start: 5505911

End: 5507194

Strand: Direct

Name: ygjG [C]

Synonym: mlr6714

Alternate gene names: 13475601

Gene position: 5505911-5507194 (Clockwise)

Preceding gene: 13475599

Following gene: 13475602

Centisome position: 78.25

GC content: 62.07

Gene sequence:

>1284_bases
ATGTATGACTTCGGCCCCTTCGAGTTCGAGTCGAAGCAGGATTTTTTCGACAAGGCAATGCGTTTCTGGAATCCCGACAA
GACCAGGTTCTGGCAGAAGGCCGGGATCGATCTGGTGATCGGCAAGCGGGAGGGTTATTTCCTCTACGACATGTCGGGGC
GCCGCCTGATCGACCTGCACCTCAATGGCGGCACCTACAATCTCGGTCACCGCAATCCGGAGCTGGTCGAGACGCTGAAG
AGCGCGCTCGACTATTTCGACATAGGCAACCACTGGTTCCCTTCCGTGGCGCGAACGGCGCTGGCCGAATCCCTCGTCAA
TGTCTCGCCAGGAATGAAATACGCGATCTTCGCGCCGGGCGGCGCGGAGGCGGTGGACATCGCCATCAAGAGCGCCCGCT
ATGCCACCAAGCGGCGCAAGATCGTGTCGATCATCAAGGGCTATCACGGACATTCGGGGCTCGCCGTGGCGACCGGCGAC
GATCGCTTCACCAAGATCTTTCTTTCCGACCAGCCGGAGACGTTCATCCAGGTTCCCTTCAACGATATCGACGCCATGGA
ACGGGCGCTCGAGGGCGAAGACGTCGCGGCGCTGATCATGGAGACAATCCCCGCCACTTACGGCTTCCCGATGCCGAAGG
ATGGCTATCTCAGCGCCTGCAAGGCGCTGTGCGAAAAGCATGGCGCGATGTACATCGCCGACGAGGTCCAGACCGGCCTG
ATGCGCACCGGCAGCATGTGGGGCTGGCAGGCCTATGGCGTCCAGCCGGACATCATGGTGACGGCAAAGGGCCTGTCCGG
CGGCCTCTATCCGATCAGCGCGGCGTTGGTGAACGAGAGAGCCGGCGGCTGGCTCAACGAGGATGGGGCGGCCCACATTT
CGACCACCGGCGGGGCCGAACTCGGCTGTGTCGTCGGCCACAAGGTCATCGAGATGCTGCAGCGGCCCGAACTGGTGGCC
AATGTCGGGACCGTGACCGAGTTCATGGCGCAGGCCATGCGCGAGATGCTGGTTCGTCACGGCGATATCTTCACCGGGGT
GCGCCAGAAGGGCGTGATCCTCGGGCTGGAATTCAGCAATCACCTCGAAGGCGCCGTCTTCGTGTCGCGTGCACTCTACG
AGCAGGGCGTCTGGGCGATCTTCTCGTCGCTCGACAAGCGGGTGCTGCAATGGAAGCCCGGTGTTCTTCTGGATCACGAA
ACCTGTCGGGACATCATGGATCGCTTCGATGCGGCAATGCCGCGCGCTCGGGAGTTGCTGCATCAGGCAGGCAAGGCGAG
TTGA

Upstream 100 bases:

>100_bases
CTCTCCACCCTTTCTCGCCGGCTTGTAATCCTGCATCATCCGGCGGACGAGCCTCGCCCGCTCCGCTGCGCGCCGATCAA
CCTTTGAGGACCAGACAGGC

Downstream 100 bases:

>100_bases
CATGGTCCAGCCCTCGTTGAAATTGTTGGGCGTCCAGTTCGAGCTGGCGGCTGGGCCTGCCGGGATCGCGCGGGTTCCGG
TAGGGGATAGGTCTGCAAGG

Product: ornithine-oxo-acid transaminase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MYDFGPFEFESKQDFFDKAMRFWNPDKTRFWQKAGIDLVIGKREGYFLYDMSGRRLIDLHLNGGTYNLGHRNPELVETLK
SALDYFDIGNHWFPSVARTALAESLVNVSPGMKYAIFAPGGAEAVDIAIKSARYATKRRKIVSIIKGYHGHSGLAVATGD
DRFTKIFLSDQPETFIQVPFNDIDAMERALEGEDVAALIMETIPATYGFPMPKDGYLSACKALCEKHGAMYIADEVQTGL
MRTGSMWGWQAYGVQPDIMVTAKGLSGGLYPISAALVNERAGGWLNEDGAAHISTTGGAELGCVVGHKVIEMLQRPELVA
NVGTVTEFMAQAMREMLVRHGDIFTGVRQKGVILGLEFSNHLEGAVFVSRALYEQGVWAIFSSLDKRVLQWKPGVLLDHE
TCRDIMDRFDAAMPRARELLHQAGKAS

Sequences:

>Translated_427_residues
MYDFGPFEFESKQDFFDKAMRFWNPDKTRFWQKAGIDLVIGKREGYFLYDMSGRRLIDLHLNGGTYNLGHRNPELVETLK
SALDYFDIGNHWFPSVARTALAESLVNVSPGMKYAIFAPGGAEAVDIAIKSARYATKRRKIVSIIKGYHGHSGLAVATGD
DRFTKIFLSDQPETFIQVPFNDIDAMERALEGEDVAALIMETIPATYGFPMPKDGYLSACKALCEKHGAMYIADEVQTGL
MRTGSMWGWQAYGVQPDIMVTAKGLSGGLYPISAALVNERAGGWLNEDGAAHISTTGGAELGCVVGHKVIEMLQRPELVA
NVGTVTEFMAQAMREMLVRHGDIFTGVRQKGVILGLEFSNHLEGAVFVSRALYEQGVWAIFSSLDKRVLQWKPGVLLDHE
TCRDIMDRFDAAMPRARELLHQAGKAS
>Mature_427_residues
MYDFGPFEFESKQDFFDKAMRFWNPDKTRFWQKAGIDLVIGKREGYFLYDMSGRRLIDLHLNGGTYNLGHRNPELVETLK
SALDYFDIGNHWFPSVARTALAESLVNVSPGMKYAIFAPGGAEAVDIAIKSARYATKRRKIVSIIKGYHGHSGLAVATGD
DRFTKIFLSDQPETFIQVPFNDIDAMERALEGEDVAALIMETIPATYGFPMPKDGYLSACKALCEKHGAMYIADEVQTGL
MRTGSMWGWQAYGVQPDIMVTAKGLSGGLYPISAALVNERAGGWLNEDGAAHISTTGGAELGCVVGHKVIEMLQRPELVA
NVGTVTEFMAQAMREMLVRHGDIFTGVRQKGVILGLEFSNHLEGAVFVSRALYEQGVWAIFSSLDKRVLQWKPGVLLDHE
TCRDIMDRFDAAMPRARELLHQAGKAS

Specific function: Unknown

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=328, Percent_Identity=31.7073170731707, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI284507298, Length=241, Percent_Identity=34.8547717842324, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI37574042, Length=435, Percent_Identity=22.5287356321839, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI24119277, Length=411, Percent_Identity=22.6277372262774, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI226442705, Length=437, Percent_Identity=22.4256292906178, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI226442709, Length=375, Percent_Identity=22.6666666666667, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI13994255, Length=401, Percent_Identity=25.1870324189526, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI145693181, Length=386, Percent_Identity=32.3834196891192, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1788044, Length=376, Percent_Identity=28.7234042553192, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1789759, Length=388, Percent_Identity=28.3505154639175, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787560, Length=253, Percent_Identity=32.8063241106719, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1789016, Length=342, Percent_Identity=25.7309941520468, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786349, Length=345, Percent_Identity=25.7971014492754, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786991, Length=403, Percent_Identity=25.8064516129032, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25144271, Length=411, Percent_Identity=27.7372262773723, Blast_Score=148, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI25144274, Length=233, Percent_Identity=32.1888412017167, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI32564660, Length=404, Percent_Identity=24.7524752475248, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324432, Length=395, Percent_Identity=24.8101265822785, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323470, Length=342, Percent_Identity=26.0233918128655, Blast_Score=100, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6324386, Length=342, Percent_Identity=26.0233918128655, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21357415, Length=380, Percent_Identity=28.4210526315789, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI161085790, Length=425, Percent_Identity=26.3529411764706, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28574759, Length=410, Percent_Identity=26.8292682926829, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI21356575, Length=357, Percent_Identity=24.9299719887955, Blast_Score=108, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 47321; Mature: 47321

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDFGPFEFESKQDFFDKAMRFWNPDKTRFWQKAGIDLVIGKREGYFLYDMSGRRLIDLH
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCEEEEECCCCEEEEECCCCEEEEEE
LNGGTYNLGHRNPELVETLKSALDYFDIGNHWFPSVARTALAESLVNVSPGMKYAIFAPG
ECCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCC
GAEAVDIAIKSARYATKRRKIVSIIKGYHGHSGLAVATGDDRFTKIFLSDQPETFIQVPF
CCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCEEEECCC
NDIDAMERALEGEDVAALIMETIPATYGFPMPKDGYLSACKALCEKHGAMYIADEVQTGL
CHHHHHHHHHCCCHHHHHHHHHHCHHCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHH
MRTGSMWGWQAYGVQPDIMVTAKGLSGGLYPISAALVNERAGGWLNEDGAAHISTTGGAE
HHCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCC
LGCVVGHKVIEMLQRPELVANVGTVTEFMAQAMREMLVRHGDIFTGVRQKGVILGLEFSN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEECCC
HLEGAVFVSRALYEQGVWAIFSSLDKRVLQWKPGVLLDHETCRDIMDRFDAAMPRARELL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCHHHHHHH
HQAGKAS
HHCCCCC
>Mature Secondary Structure
MYDFGPFEFESKQDFFDKAMRFWNPDKTRFWQKAGIDLVIGKREGYFLYDMSGRRLIDLH
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCEEEEECCCCEEEEECCCCEEEEEE
LNGGTYNLGHRNPELVETLKSALDYFDIGNHWFPSVARTALAESLVNVSPGMKYAIFAPG
ECCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCC
GAEAVDIAIKSARYATKRRKIVSIIKGYHGHSGLAVATGDDRFTKIFLSDQPETFIQVPF
CCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCEEEECCC
NDIDAMERALEGEDVAALIMETIPATYGFPMPKDGYLSACKALCEKHGAMYIADEVQTGL
CHHHHHHHHHCCCHHHHHHHHHHCHHCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHH
MRTGSMWGWQAYGVQPDIMVTAKGLSGGLYPISAALVNERAGGWLNEDGAAHISTTGGAE
HHCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCC
LGCVVGHKVIEMLQRPELVANVGTVTEFMAQAMREMLVRHGDIFTGVRQKGVILGLEFSN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEECCC
HLEGAVFVSRALYEQGVWAIFSSLDKRVLQWKPGVLLDHETCRDIMDRFDAAMPRARELL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCHHHHHHH
HQAGKAS
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]