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The map label for this gene is rsbU [H]

Identifier: 13475593

GI number: 13475593

Start: 5494804

End: 5497170

Strand: Reverse

Name: rsbU [H]

Synonym: mll6700

Alternate gene names: 13475593

Gene position: 5497170-5494804 (Counterclockwise)

Preceding gene: 13475594

Following gene: 13475592

Centisome position: 78.13

GC content: 59.06

Gene sequence:

>2367_bases
ATGAAAGCCGACAATGAGCCTACACCACGCTTCGGCCTGCATTCCTTTCGAGCGAAATTCGTATTGGTCGTCGGCGGCGC
CGTACTGTTCGACCTCCTGTTGAGCGGCGGCCTGGCGCTTTGGAACGTTCAAAAGCTGTCGCGCGACGCCACATCGGAAG
TCGGTGAGGGCCTGACGACCGCAAACCAGGAATACATTCGTTCCTATGCCGAGTCGACGGCGTTGAGCGTCGACCTGTTG
CTCGATCGGGTTCATGGGGACGTCAAGGCGCTGGCCGGCGTGCTGCAGGCCCAGATCGACGATCCGAGTAGGCAGCAGCA
GATCGGAGCGACGCTTTCGCATCAGGCGCCCGGCTCCGTGAAGATCGTCTACGATGCGCAGGGCAATTGGGCGCAGAATC
TGCCGGGCTCGCCTTCCGTGATAAGTGTCTGGGGCTACCTGCTGGGCGCCGACCACAGTCCGCTGCCGGGCGTTCAGAAG
GAAATAGAAGACAGTACCGTGATCGATCTCGTCGCGCCGACCCTCATGGCCAGCGGGGCGTCCAAGCTGCAGATGTACTA
TATTGGTCCAAAAGAACGACCGATCTTCAGGACGGTACCATATACGAACCAGGCGCAGACCTTCGACCGGCTCTATCCAG
GCCACAACAAGGCGGAGTTCTGGGAGTTCTTCTTTCCGGGAATCTATGGTTCATGGCAGCAATGGGCCAAGAACCCAGCC
TCACGTCCGGTCCCTGACGACATAACCCAGACCGCGCCTTACACCGATGCGATCACGGGAAAGCTGATCGTCAGCTTTTT
CCACCCGCTGTGGACGCTTGATCGCACCGGTATCGCCGGCACGGCGGGGGCAGACATCACGCTCGATCAGCTCGCGGAAG
TCGTCGAAAGGGTGAAGATCGCTCAAACCGGATTCGGCTTCCTCACGATGTCGACTGGCAATGTGGTGGCGATCAATCCG
TCTGGCCAGGCGATCATCGGCCTGACTTCGTCGAGCGATGCCGGCACGCAGGGCGTCACCGGCTTGGAAAGGTCTCTGCG
GGGAAGTACCCAGCCGGCTATCGCGTCGCTGCCTCTCGACCAGAACAATGACGGTGTCATCCAGCACATCATGCTCGACA
ACAAGGGCGAACACGTTCCCTACATCGTTGTCCTCAAGAGATTGAAGCCGACCAATCTATGGAGTTCGGGACCGGTCAAG
TCCGAAACGATGTCGGTCGGGATCGTCGTTCCCGAACGGGAGATCTATGCATCCCTGTTCGCCGCGCAGGAGAGCATTTC
GCGCGCAACCAATCGCATCCTGCTGTTTCAGATCGCGGCGATCACTGTTTCGCTTCTGATTGTCTTTGCGGCCGTGCTCG
GAATTTCGAAGCGGATCACGGCCGGCCTCAGGGCGCTTGCCAGTGCCGCCCAGAAGCTCCAGTCCAAAGATTATTCAGTG
CGCGTGAGCATTCCAACCCGCGACGAGGTTGGAGCGGCAGGGATTGCCTTCAACCGGATGGCTGAGGAGATCAGCTTTCA
CACTGAAAACCTCGAGCAACTCGTCGACGAACGAACCAAGGAGCTCGGGGACGCCAATCAGGAGATTTCCGCACTCAACG
AAAAGTTGCGGGACGAGAACGTCCGCCTCGGTGCCGAACTCGCGGTTGCCAGACACATCCAGATGATGGTCCTGCCGAAA
CCAATCGAACTCGAAGCGATTCCGGGGCTGGAGATCGCAGCGTATATGCGGCCGGCAGACGAGGTCGGCGGGGACTACTA
CGACGTTCTGCAGAACGGTTCACGGGTCAAGGTCGGCATTGGCGACGTGACCGGTCATGGTCTCGAAAGCGGCGTGCTGA
TGCTGATGGTCCAATCCGTCGCACGCGCGCTGCAGGAGACCAACGAAGCGGATCCGCACCAGTTTCTGGATCGGTTGAAC
AGAGCGATCTACAAGAACATTGAGCGGACGAACACCGACAAGCATCTCTCGCTGGCCTTCCTTGACTTCGAGGATGGACG
GGTAACGCTATCCGGCCAACATGAGGACGTTCTTGTCGTCCGTGCGGGCGGGGAAGTCGAACGTATCGACACGCTTGATC
TGGGTCTGCCGGTTGGTCTGGAGAGTGACATCTCGCCGTTCATTGACACGTATGACATCAAGTTCGGGACCGGCGACGTG
ATCGTGCTGCACACCGACGGTGTGACCGAGGCGGAAGACCAGGACAGAAGGCTGTTCGGGTTCGAGCGCCTTTGCCAGAG
CGCACGAAAACGTCACGGCGAGAGCGCCGAGGAAATCAAAACCGGGATCGTCGAGGATCTGATGGCCCATATCGGAATCC
AGAAGATCCACGACGACATCACCCTCGTGATCATAAGGCACACATAG

Upstream 100 bases:

>100_bases
CACGGTTCCGGCAGGGCTTCCAGGACCACATTTTCGCTGCACTCCACCCCAAGGGCTACGCGGGTTGGCCGATCTGGGTC
GCATCGGGGCAACGGCCACA

Downstream 100 bases:

>100_bases
ACATGACCACGCTGTTCGGCACATCTGAGCTCGCTATCGGGACGATGGAAGGTGTCAGTCGTGTGCGGCTGTTCGACGGA
CCACTCGACTTGAGTTGGCG

Product: hypothetical protein

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 788; Mature: 788

Protein sequence:

>788_residues
MKADNEPTPRFGLHSFRAKFVLVVGGAVLFDLLLSGGLALWNVQKLSRDATSEVGEGLTTANQEYIRSYAESTALSVDLL
LDRVHGDVKALAGVLQAQIDDPSRQQQIGATLSHQAPGSVKIVYDAQGNWAQNLPGSPSVISVWGYLLGADHSPLPGVQK
EIEDSTVIDLVAPTLMASGASKLQMYYIGPKERPIFRTVPYTNQAQTFDRLYPGHNKAEFWEFFFPGIYGSWQQWAKNPA
SRPVPDDITQTAPYTDAITGKLIVSFFHPLWTLDRTGIAGTAGADITLDQLAEVVERVKIAQTGFGFLTMSTGNVVAINP
SGQAIIGLTSSSDAGTQGVTGLERSLRGSTQPAIASLPLDQNNDGVIQHIMLDNKGEHVPYIVVLKRLKPTNLWSSGPVK
SETMSVGIVVPEREIYASLFAAQESISRATNRILLFQIAAITVSLLIVFAAVLGISKRITAGLRALASAAQKLQSKDYSV
RVSIPTRDEVGAAGIAFNRMAEEISFHTENLEQLVDERTKELGDANQEISALNEKLRDENVRLGAELAVARHIQMMVLPK
PIELEAIPGLEIAAYMRPADEVGGDYYDVLQNGSRVKVGIGDVTGHGLESGVLMLMVQSVARALQETNEADPHQFLDRLN
RAIYKNIERTNTDKHLSLAFLDFEDGRVTLSGQHEDVLVVRAGGEVERIDTLDLGLPVGLESDISPFIDTYDIKFGTGDV
IVLHTDGVTEAEDQDRRLFGFERLCQSARKRHGESAEEIKTGIVEDLMAHIGIQKIHDDITLVIIRHT

Sequences:

>Translated_788_residues
MKADNEPTPRFGLHSFRAKFVLVVGGAVLFDLLLSGGLALWNVQKLSRDATSEVGEGLTTANQEYIRSYAESTALSVDLL
LDRVHGDVKALAGVLQAQIDDPSRQQQIGATLSHQAPGSVKIVYDAQGNWAQNLPGSPSVISVWGYLLGADHSPLPGVQK
EIEDSTVIDLVAPTLMASGASKLQMYYIGPKERPIFRTVPYTNQAQTFDRLYPGHNKAEFWEFFFPGIYGSWQQWAKNPA
SRPVPDDITQTAPYTDAITGKLIVSFFHPLWTLDRTGIAGTAGADITLDQLAEVVERVKIAQTGFGFLTMSTGNVVAINP
SGQAIIGLTSSSDAGTQGVTGLERSLRGSTQPAIASLPLDQNNDGVIQHIMLDNKGEHVPYIVVLKRLKPTNLWSSGPVK
SETMSVGIVVPEREIYASLFAAQESISRATNRILLFQIAAITVSLLIVFAAVLGISKRITAGLRALASAAQKLQSKDYSV
RVSIPTRDEVGAAGIAFNRMAEEISFHTENLEQLVDERTKELGDANQEISALNEKLRDENVRLGAELAVARHIQMMVLPK
PIELEAIPGLEIAAYMRPADEVGGDYYDVLQNGSRVKVGIGDVTGHGLESGVLMLMVQSVARALQETNEADPHQFLDRLN
RAIYKNIERTNTDKHLSLAFLDFEDGRVTLSGQHEDVLVVRAGGEVERIDTLDLGLPVGLESDISPFIDTYDIKFGTGDV
IVLHTDGVTEAEDQDRRLFGFERLCQSARKRHGESAEEIKTGIVEDLMAHIGIQKIHDDITLVIIRHT
>Mature_788_residues
MKADNEPTPRFGLHSFRAKFVLVVGGAVLFDLLLSGGLALWNVQKLSRDATSEVGEGLTTANQEYIRSYAESTALSVDLL
LDRVHGDVKALAGVLQAQIDDPSRQQQIGATLSHQAPGSVKIVYDAQGNWAQNLPGSPSVISVWGYLLGADHSPLPGVQK
EIEDSTVIDLVAPTLMASGASKLQMYYIGPKERPIFRTVPYTNQAQTFDRLYPGHNKAEFWEFFFPGIYGSWQQWAKNPA
SRPVPDDITQTAPYTDAITGKLIVSFFHPLWTLDRTGIAGTAGADITLDQLAEVVERVKIAQTGFGFLTMSTGNVVAINP
SGQAIIGLTSSSDAGTQGVTGLERSLRGSTQPAIASLPLDQNNDGVIQHIMLDNKGEHVPYIVVLKRLKPTNLWSSGPVK
SETMSVGIVVPEREIYASLFAAQESISRATNRILLFQIAAITVSLLIVFAAVLGISKRITAGLRALASAAQKLQSKDYSV
RVSIPTRDEVGAAGIAFNRMAEEISFHTENLEQLVDERTKELGDANQEISALNEKLRDENVRLGAELAVARHIQMMVLPK
PIELEAIPGLEIAAYMRPADEVGGDYYDVLQNGSRVKVGIGDVTGHGLESGVLMLMVQSVARALQETNEADPHQFLDRLN
RAIYKNIERTNTDKHLSLAFLDFEDGRVTLSGQHEDVLVVRAGGEVERIDTLDLGLPVGLESDISPFIDTYDIKFGTGDV
IVLHTDGVTEAEDQDRRLFGFERLCQSARKRHGESAEEIKTGIVEDLMAHIGIQKIHDDITLVIIRHT

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 85924; Mature: 85924

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKADNEPTPRFGLHSFRAKFVLVVGGAVLFDLLLSGGLALWNVQKLSRDATSEVGEGLTT
CCCCCCCCCCCCHHHHHHEEEEEECHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCC
ANQEYIRSYAESTALSVDLLLDRVHGDVKALAGVLQAQIDDPSRQQQIGATLSHQAPGSV
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHCCHHCCCCCCCE
KIVYDAQGNWAQNLPGSPSVISVWGYLLGADHSPLPGVQKEIEDSTVIDLVAPTLMASGA
EEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCC
SKLQMYYIGPKERPIFRTVPYTNQAQTFDRLYPGHNKAEFWEFFFPGIYGSWQQWAKNPA
CEEEEEEECCCCCCEEEECCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHCCCC
SRPVPDDITQTAPYTDAITGKLIVSFFHPLWTLDRTGIAGTAGADITLDQLAEVVERVKI
CCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AQTGFGFLTMSTGNVVAINPSGQAIIGLTSSSDAGTQGVTGLERSLRGSTQPAIASLPLD
HHCCCCEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEECCCC
QNNDGVIQHIMLDNKGEHVPYIVVLKRLKPTNLWSSGPVKSETMSVGIVVPEREIYASLF
CCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHH
AAQESISRATNRILLFQIAAITVSLLIVFAAVLGISKRITAGLRALASAAQKLQSKDYSV
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RVSIPTRDEVGAAGIAFNRMAEEISFHTENLEQLVDERTKELGDANQEISALNEKLRDEN
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
VRLGAELAVARHIQMMVLPKPIELEAIPGLEIAAYMRPADEVGGDYYDVLQNGSRVKVGI
CCCCHHHHHHHHEEEEECCCCCCEECCCCCEEHHHCCCHHHHCCHHHHHHCCCCEEEEEE
GDVTGHGLESGVLMLMVQSVARALQETNEADPHQFLDRLNRAIYKNIERTNTDKHLSLAF
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
LDFEDGRVTLSGQHEDVLVVRAGGEVERIDTLDLGLPVGLESDISPFIDTYDIKFGTGDV
EEECCCEEEECCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCE
IVLHTDGVTEAEDQDRRLFGFERLCQSARKRHGESAEEIKTGIVEDLMAHIGIQKIHDDI
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHCCCCE
TLVIIRHT
EEEEEECC
>Mature Secondary Structure
MKADNEPTPRFGLHSFRAKFVLVVGGAVLFDLLLSGGLALWNVQKLSRDATSEVGEGLTT
CCCCCCCCCCCCHHHHHHEEEEEECHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCC
ANQEYIRSYAESTALSVDLLLDRVHGDVKALAGVLQAQIDDPSRQQQIGATLSHQAPGSV
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHCCHHCCCCCCCE
KIVYDAQGNWAQNLPGSPSVISVWGYLLGADHSPLPGVQKEIEDSTVIDLVAPTLMASGA
EEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCC
SKLQMYYIGPKERPIFRTVPYTNQAQTFDRLYPGHNKAEFWEFFFPGIYGSWQQWAKNPA
CEEEEEEECCCCCCEEEECCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHCCCC
SRPVPDDITQTAPYTDAITGKLIVSFFHPLWTLDRTGIAGTAGADITLDQLAEVVERVKI
CCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AQTGFGFLTMSTGNVVAINPSGQAIIGLTSSSDAGTQGVTGLERSLRGSTQPAIASLPLD
HHCCCCEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEECCCC
QNNDGVIQHIMLDNKGEHVPYIVVLKRLKPTNLWSSGPVKSETMSVGIVVPEREIYASLF
CCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHH
AAQESISRATNRILLFQIAAITVSLLIVFAAVLGISKRITAGLRALASAAQKLQSKDYSV
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RVSIPTRDEVGAAGIAFNRMAEEISFHTENLEQLVDERTKELGDANQEISALNEKLRDEN
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
VRLGAELAVARHIQMMVLPKPIELEAIPGLEIAAYMRPADEVGGDYYDVLQNGSRVKVGI
CCCCHHHHHHHHEEEEECCCCCCEECCCCCEEHHHCCCHHHHCCHHHHHHCCCCEEEEEE
GDVTGHGLESGVLMLMVQSVARALQETNEADPHQFLDRLNRAIYKNIERTNTDKHLSLAF
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
LDFEDGRVTLSGQHEDVLVVRAGGEVERIDTLDLGLPVGLESDISPFIDTYDIKFGTGDV
EEECCCEEEECCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCE
IVLHTDGVTEAEDQDRRLFGFERLCQSARKRHGESAEEIKTGIVEDLMAHIGIQKIHDDI
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHCCCCE
TLVIIRHT
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]