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The map label for this gene is 13475505

Identifier: 13475505

GI number: 13475505

Start: 5401288

End: 5402778

Strand: Reverse

Name: 13475505

Synonym: mll6593

Alternate gene names: NA

Gene position: 5402778-5401288 (Counterclockwise)

Preceding gene: 13475507

Following gene: 13475503

Centisome position: 76.79

GC content: 61.1

Gene sequence:

>1491_bases
ATGGGGCCGGTCGAGGCGATCGAGACCCATATCTCACGAATTTTCTTGATCGGTGGACGTGCCTTTAAGATGAAACGGGC
GGTCAAGCTGCCCTATGTCGATTTCTCGACGCCAGCACTAAGGCTGGCCGCTTGCGAAAAAGAGGTGGAACTCAACGCCA
GGACCGCACCCGGCCTCTATCTGGGCGTGCGGCGCATTACCCGCGAAGCCGACGGCAAACTCGTTTTCGATGGCGCTGGC
CAAATGGTCGATGCGGTGATCGAGATGGTCCGGTTTGATCAGTCGAGGCTCCTCGATCGGATGGCGACCGCAGGAGAACT
GACGCCATCGCTGATGACGGCCGTCGCACGCATGATCGTGGGATATCACCGTGCCGCGCCGAAGATCCACAACGGCACCG
GCTCGTTCAATTTGATGGGCGTGCTCGACATCAACGAGGCCGGCTTTGGCACCAGTCACGTTTTTACAAAACGGGAGATC
GAGACGTTTGCCGGGGCTTTCCGCACCGCACTCGCGCGCCATTCCGGATTGCTGGATCGCCGGGAGGCCGCGGGCAAAAT
CCGCCAGTGTCATGGCGATCTGCACCTGCGCAACATCTGCCTTTTCGATGGCGAGCCTCGCCTCTTCGATTGCATCGAAT
TCAATGACCAGATCGCCAGCATCGATGTTCTGTACGACCTTGCCTTCTTGCTGATGGACCTTTGGCATCGCGGTTTCCCA
GAGCTCGCCAATCTCGTGATGAACCGCTACCTCGACGAGGCCGATGACGAGGATGGCTTTGTCCTGCTGCCTTTTTTCAT
CGCGGTGCGGGCAGCCGTGCGCGCGCATGTCACCGCGACCCAGGTCGAGGAAGGCAGCGCCGATTCCGGGAAATTGGCTG
CCGAGGCCCGATCCTATTTCGAACTGGCCCGAACATTTCTGCAGCAAACGCCGCCGAGGCTCGTTGCCATCGGCGGCCTC
AGTGGTTCAGGCAAGACGACCATTGCCGAGGCGCTCGCCGCCCATGTCGGTGCGCCGCCCGGTGCGCGCATAGTCGAAAG
CGACCGCATCCGCAAAGCGATGCACGGCGTGCCCGCCGAGACCAGGCTGCCGGACAACGCCTATCGTCCTGATGTGTCCG
ATCGCGTCTACAACGAAATGACATGGCGCGCCGGCCTGATTCTCTCCGAGGGCGGCTCGGTTGTAGCTGATGCGGTTTTC
GACAGACCGGCCGATCGTGAGCGAATCGAGAAGGCGGCGCGAGACCGGGGTATTCCATTCTTCGGTTTCTGGCTGGAGGC
GGATCCACTCGTCCTTTGGCAACGGGTCAGCGAACGCAAGGGCGGTCCTTCGGATGCAACGGTCGATATCCTTTCGCGTC
AATTGCAGCGAAAAGCCGGCCAGGCCAGCTGGCGCAGGACCGATTCCGATCGAAAACCCGTCGACATCGCCGCGGAACTG
AGGAGATGTTGGCAGCGCGATGCTTCCGAAACCCTGCGCACGGCCTCCTGA

Upstream 100 bases:

>100_bases
CAGTCTCCGCACGACGCAGGCATCGAAGAGGCCGGACATGGTCGTTGACGAGCAGCAATCCGCTATCGCGCTCCTGCTTG
ATCCTGCCTCCTATGGTGCG

Downstream 100 bases:

>100_bases
CTGTTGCGGATGATCGACCTCAACCGAGTTCGAGCTTGGCCTCGACAAGCCCTGGCTCGTTCGGAAGATGCATCAAGGAG
AAGCCGAATTCACGGCACAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MGPVEAIETHISRIFLIGGRAFKMKRAVKLPYVDFSTPALRLAACEKEVELNARTAPGLYLGVRRITREADGKLVFDGAG
QMVDAVIEMVRFDQSRLLDRMATAGELTPSLMTAVARMIVGYHRAAPKIHNGTGSFNLMGVLDINEAGFGTSHVFTKREI
ETFAGAFRTALARHSGLLDRREAAGKIRQCHGDLHLRNICLFDGEPRLFDCIEFNDQIASIDVLYDLAFLLMDLWHRGFP
ELANLVMNRYLDEADDEDGFVLLPFFIAVRAAVRAHVTATQVEEGSADSGKLAAEARSYFELARTFLQQTPPRLVAIGGL
SGSGKTTIAEALAAHVGAPPGARIVESDRIRKAMHGVPAETRLPDNAYRPDVSDRVYNEMTWRAGLILSEGGSVVADAVF
DRPADRERIEKAARDRGIPFFGFWLEADPLVLWQRVSERKGGPSDATVDILSRQLQRKAGQASWRRTDSDRKPVDIAAEL
RRCWQRDASETLRTAS

Sequences:

>Translated_496_residues
MGPVEAIETHISRIFLIGGRAFKMKRAVKLPYVDFSTPALRLAACEKEVELNARTAPGLYLGVRRITREADGKLVFDGAG
QMVDAVIEMVRFDQSRLLDRMATAGELTPSLMTAVARMIVGYHRAAPKIHNGTGSFNLMGVLDINEAGFGTSHVFTKREI
ETFAGAFRTALARHSGLLDRREAAGKIRQCHGDLHLRNICLFDGEPRLFDCIEFNDQIASIDVLYDLAFLLMDLWHRGFP
ELANLVMNRYLDEADDEDGFVLLPFFIAVRAAVRAHVTATQVEEGSADSGKLAAEARSYFELARTFLQQTPPRLVAIGGL
SGSGKTTIAEALAAHVGAPPGARIVESDRIRKAMHGVPAETRLPDNAYRPDVSDRVYNEMTWRAGLILSEGGSVVADAVF
DRPADRERIEKAARDRGIPFFGFWLEADPLVLWQRVSERKGGPSDATVDILSRQLQRKAGQASWRRTDSDRKPVDIAAEL
RRCWQRDASETLRTAS
>Mature_495_residues
GPVEAIETHISRIFLIGGRAFKMKRAVKLPYVDFSTPALRLAACEKEVELNARTAPGLYLGVRRITREADGKLVFDGAGQ
MVDAVIEMVRFDQSRLLDRMATAGELTPSLMTAVARMIVGYHRAAPKIHNGTGSFNLMGVLDINEAGFGTSHVFTKREIE
TFAGAFRTALARHSGLLDRREAAGKIRQCHGDLHLRNICLFDGEPRLFDCIEFNDQIASIDVLYDLAFLLMDLWHRGFPE
LANLVMNRYLDEADDEDGFVLLPFFIAVRAAVRAHVTATQVEEGSADSGKLAAEARSYFELARTFLQQTPPRLVAIGGLS
GSGKTTIAEALAAHVGAPPGARIVESDRIRKAMHGVPAETRLPDNAYRPDVSDRVYNEMTWRAGLILSEGGSVVADAVFD
RPADRERIEKAARDRGIPFFGFWLEADPLVLWQRVSERKGGPSDATVDILSRQLQRKAGQASWRRTDSDRKPVDIAAELR
RCWQRDASETLRTAS

Specific function: Some isolated peptides of this protein are able to bind to human U937 monocytoblastic and A549 epithelial cell lines [H]

COG id: COG2187

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR010488 [H]

Pfam domain/function: PF06414 Zeta_toxin [H]

EC number: NA

Molecular weight: Translated: 54905; Mature: 54774

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPVEAIETHISRIFLIGGRAFKMKRAVKLPYVDFSTPALRLAACEKEVELNARTAPGLY
CCHHHHHHHHHHHEEEECCCHHHHHHHEECCEECCCCCHHHHHHHHHHHHCCCCCCCHHH
LGVRRITREADGKLVFDGAGQMVDAVIEMVRFDQSRLLDRMATAGELTPSLMTAVARMIV
HHHHHHHHHCCCCEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
GYHRAAPKIHNGTGSFNLMGVLDINEAGFGTSHVFTKREIETFAGAFRTALARHSGLLDR
HHHHCCCCEECCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
REAAGKIRQCHGDLHLRNICLFDGEPRLFDCIEFNDQIASIDVLYDLAFLLMDLWHRGFP
HHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCH
ELANLVMNRYLDEADDEDGFVLLPFFIAVRAAVRAHVTATQVEEGSADSGKLAAEARSYF
HHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ELARTFLQQTPPRLVAIGGLSGSGKTTIAEALAAHVGAPPGARIVESDRIRKAMHGVPAE
HHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCC
TRLPDNAYRPDVSDRVYNEMTWRAGLILSEGGSVVADAVFDRPADRERIEKAARDRGIPF
CCCCCCCCCCCHHHHHHHHHHHHHCEEEECCCCEEHHHHHCCCCCHHHHHHHHHHCCCCE
FGFWLEADPLVLWQRVSERKGGPSDATVDILSRQLQRKAGQASWRRTDSDRKPVDIAAEL
EEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHH
RRCWQRDASETLRTAS
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GPVEAIETHISRIFLIGGRAFKMKRAVKLPYVDFSTPALRLAACEKEVELNARTAPGLY
CHHHHHHHHHHHEEEECCCHHHHHHHEECCEECCCCCHHHHHHHHHHHHCCCCCCCHHH
LGVRRITREADGKLVFDGAGQMVDAVIEMVRFDQSRLLDRMATAGELTPSLMTAVARMIV
HHHHHHHHHCCCCEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
GYHRAAPKIHNGTGSFNLMGVLDINEAGFGTSHVFTKREIETFAGAFRTALARHSGLLDR
HHHHCCCCEECCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
REAAGKIRQCHGDLHLRNICLFDGEPRLFDCIEFNDQIASIDVLYDLAFLLMDLWHRGFP
HHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCH
ELANLVMNRYLDEADDEDGFVLLPFFIAVRAAVRAHVTATQVEEGSADSGKLAAEARSYF
HHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ELARTFLQQTPPRLVAIGGLSGSGKTTIAEALAAHVGAPPGARIVESDRIRKAMHGVPAE
HHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCC
TRLPDNAYRPDVSDRVYNEMTWRAGLILSEGGSVVADAVFDRPADRERIEKAARDRGIPF
CCCCCCCCCCCHHHHHHHHHHHHHCEEEECCCCEEHHHHHCCCCCHHHHHHHHHHCCCCE
FGFWLEADPLVLWQRVSERKGGPSDATVDILSRQLQRKAGQASWRRTDSDRKPVDIAAEL
EEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHH
RRCWQRDASETLRTAS
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]