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The map label for this gene is flhA [C]

Identifier: 13475310

GI number: 13475310

Start: 5166041

End: 5168086

Strand: Direct

Name: flhA [C]

Synonym: mlr6348

Alternate gene names: 13475310

Gene position: 5166041-5168086 (Clockwise)

Preceding gene: 13475309

Following gene: 13475311

Centisome position: 73.42

GC content: 56.35

Gene sequence:

>2046_bases
ATGGCCAACGTCCTGCGTAAGTTCATCAACCGTTCGCCGGCCAACCCGGACCTGATGGTCGCGTTGATGCTGCTTCTGGC
TATCGCTATGATGGTCATGCCTATCCCGATCGTGGTGGTCGACGCGCTGATAGGATTCAATATGGGACTGGCCATCCTGC
TGATGATGGTTGCCCTGTATGTCAGTACTCCACTTGATCTTTCCTCTTTGCCCGGCATCATTTTGCTTTCCACGGTGTTC
CGCCTGGCGCTCACCGTCGCAACGACGCGCCTGATCCTGGCCGAGGGGGAGGCAGGCGCCATCATCCATACGTTCGGCGA
TTTCGTGATCTCGGGCAATATCGTGGTCGGTTTCGTCATATTTCTGGTCGTCACCATGGTACAATTCATGGTCCTCGCGA
AGGGCGCCGAACGCGTGGCCGAAGTGGCGGCGCGCTTCACGCTCGACGCTCTGCCGGGTAAGCAAATGGCGGTCGACGCA
GAGCTACGCAACGGCCACATCGATGCCAACGAATCTCGCAGGCGACGCGCCGCATTGGAGAAGGAAAGCCAACTTTACGG
CGCGATGGATGGCGCGATGAAGTTTGTGAAGGGCGATTCCATCGCCGGACTGGTGGTTATCTTCATCAACATGCTGGGTG
GGATATCGATCGGCCTGCTCTCGAAGGGCATGTCCTTCGGCGATGTGCTGCATCACTATACTCTGCTAACGATAGGCGAT
GCATTGATATCGCAGATTCCGGCCCTGCTGCTATCAATTACAGCGGCGACCGTCGTCACTCGTGTCACGGGGGCGGCGAG
GGTCAACCTTGGTACCGAAATAGTGAATCAGATCACTGCCAGCAAGCGACCAGTGCGGGTCGCAGCTTGCGTCCTGGTTT
TGATGGGGTTCGTTCCTGGCTTCCCCCTGCCCGTCTTTTTGGTGTTGGCCGCAATCTTCGCCGCGATAAGCTTTGTGAAG
GGCGATGTTGTCGATACCACAAGTGCAGGGGACACTCAAAAACAAACCGCGCCCGCGCAGGAATGTCCGATCGCTTTCTT
CCTTGCGCCAGACCTGATGCATGCGATTGAACAAGTCGAATTGCAGCAGGAGATTGCACGCGTTTCGCAACTACTTTCAG
CCGATCTTGGCATTGTCGTTCCCCCCATCCCTGTCACTGTCGACCAGCAGTTGCTGGAGTCTCAGTTTCGAATAGATATC
GAGGGGGTGCCAGTTGAACAGGGTGTGTTTGATCCGAGCCAGCTGATGCTCAAAGACGATGTGGCGAACATCGAATCGAG
CGGTATCCCGTATCGGCGTGATCCAAAAACGGACAGACTCGTGGCCGACCAAAGCCATGCACCGGCTCTCAAGAGTGCCG
GCATCACACATTACGGTCCTGGCGAATTCCTCGCCTTGCGCCTCCATACAGCGTTGACCCGTTTCGCACCCCGATTGATC
GGTATTCAAGAGACCCGACAATTGATAGGCCGAATGGAGAAGGACTATTCTGATCTGGTCAAGGAGGTGCTGCGCACGAC
GCCAATACCTCGGATTGCGGATGTGCTGCGCCGGCTCCTGGATGAAGGAATCCCGATCCGCCACACCCGCCTTCTCTTAG
AAGGATTGGCGGAATGGAGCGAACGTGAGCCAAACGTTGCCCTGCTCACGGAATATATTCGTTCTGGTTTGAAGCGTCAG
ATCTGTCACCGCTATGCCAACACAGAGGGCATCGTGCCCGCCTTGGTCGTCGAACGCCAGAGTGAGGATGTGATGCGCAA
TGCAGTTCGAGATTCGGCTGCAGGACCCCACCTCGTACTAGAGGACCGGCAAAGCGAAGCGCTGCTGTCACAGGTACGTC
AGATCCTTTCGAACACAGCACCGGGTCAGACCCGCCCTGTCGTTTTAACCTCAACGGACATCCGACGCTTCGTCCGCGGC
TTTTTCACCAGAAACGGGATCGATGTTGCCGTGCTGTCTTATCAAGATATCGCCTCCGACTTTACAGTTAAACCCGCCGG
GTCCGTCAAATTCCCGCATGGATTGATCAGTGGGCTGTCAGAGTAA

Upstream 100 bases:

>100_bases
TCGCGGGCTGCCCAATGAGGGACTTGGCCCTCGGACTTCGAATGCTACGCTTCACTGCGTAGCAGCAGAATAATTCTCAA
GCGATCGTAAAGGGTCCTAG

Downstream 100 bases:

>100_bases
ACCCAATCCGTTTGCCATCGAATGAACGTGATAGCACTCTATGATAATTGGAAACCAAGCATGAATTCACACCAGAATAC
AGACGGCCGAGCATTTAGGA

Product: type III secretion inner membrane protein, HrcV

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 681; Mature: 680

Protein sequence:

>681_residues
MANVLRKFINRSPANPDLMVALMLLLAIAMMVMPIPIVVVDALIGFNMGLAILLMMVALYVSTPLDLSSLPGIILLSTVF
RLALTVATTRLILAEGEAGAIIHTFGDFVISGNIVVGFVIFLVVTMVQFMVLAKGAERVAEVAARFTLDALPGKQMAVDA
ELRNGHIDANESRRRRAALEKESQLYGAMDGAMKFVKGDSIAGLVVIFINMLGGISIGLLSKGMSFGDVLHHYTLLTIGD
ALISQIPALLLSITAATVVTRVTGAARVNLGTEIVNQITASKRPVRVAACVLVLMGFVPGFPLPVFLVLAAIFAAISFVK
GDVVDTTSAGDTQKQTAPAQECPIAFFLAPDLMHAIEQVELQQEIARVSQLLSADLGIVVPPIPVTVDQQLLESQFRIDI
EGVPVEQGVFDPSQLMLKDDVANIESSGIPYRRDPKTDRLVADQSHAPALKSAGITHYGPGEFLALRLHTALTRFAPRLI
GIQETRQLIGRMEKDYSDLVKEVLRTTPIPRIADVLRRLLDEGIPIRHTRLLLEGLAEWSEREPNVALLTEYIRSGLKRQ
ICHRYANTEGIVPALVVERQSEDVMRNAVRDSAAGPHLVLEDRQSEALLSQVRQILSNTAPGQTRPVVLTSTDIRRFVRG
FFTRNGIDVAVLSYQDIASDFTVKPAGSVKFPHGLISGLSE

Sequences:

>Translated_681_residues
MANVLRKFINRSPANPDLMVALMLLLAIAMMVMPIPIVVVDALIGFNMGLAILLMMVALYVSTPLDLSSLPGIILLSTVF
RLALTVATTRLILAEGEAGAIIHTFGDFVISGNIVVGFVIFLVVTMVQFMVLAKGAERVAEVAARFTLDALPGKQMAVDA
ELRNGHIDANESRRRRAALEKESQLYGAMDGAMKFVKGDSIAGLVVIFINMLGGISIGLLSKGMSFGDVLHHYTLLTIGD
ALISQIPALLLSITAATVVTRVTGAARVNLGTEIVNQITASKRPVRVAACVLVLMGFVPGFPLPVFLVLAAIFAAISFVK
GDVVDTTSAGDTQKQTAPAQECPIAFFLAPDLMHAIEQVELQQEIARVSQLLSADLGIVVPPIPVTVDQQLLESQFRIDI
EGVPVEQGVFDPSQLMLKDDVANIESSGIPYRRDPKTDRLVADQSHAPALKSAGITHYGPGEFLALRLHTALTRFAPRLI
GIQETRQLIGRMEKDYSDLVKEVLRTTPIPRIADVLRRLLDEGIPIRHTRLLLEGLAEWSEREPNVALLTEYIRSGLKRQ
ICHRYANTEGIVPALVVERQSEDVMRNAVRDSAAGPHLVLEDRQSEALLSQVRQILSNTAPGQTRPVVLTSTDIRRFVRG
FFTRNGIDVAVLSYQDIASDFTVKPAGSVKFPHGLISGLSE
>Mature_680_residues
ANVLRKFINRSPANPDLMVALMLLLAIAMMVMPIPIVVVDALIGFNMGLAILLMMVALYVSTPLDLSSLPGIILLSTVFR
LALTVATTRLILAEGEAGAIIHTFGDFVISGNIVVGFVIFLVVTMVQFMVLAKGAERVAEVAARFTLDALPGKQMAVDAE
LRNGHIDANESRRRRAALEKESQLYGAMDGAMKFVKGDSIAGLVVIFINMLGGISIGLLSKGMSFGDVLHHYTLLTIGDA
LISQIPALLLSITAATVVTRVTGAARVNLGTEIVNQITASKRPVRVAACVLVLMGFVPGFPLPVFLVLAAIFAAISFVKG
DVVDTTSAGDTQKQTAPAQECPIAFFLAPDLMHAIEQVELQQEIARVSQLLSADLGIVVPPIPVTVDQQLLESQFRIDIE
GVPVEQGVFDPSQLMLKDDVANIESSGIPYRRDPKTDRLVADQSHAPALKSAGITHYGPGEFLALRLHTALTRFAPRLIG
IQETRQLIGRMEKDYSDLVKEVLRTTPIPRIADVLRRLLDEGIPIRHTRLLLEGLAEWSEREPNVALLTEYIRSGLKRQI
CHRYANTEGIVPALVVERQSEDVMRNAVRDSAAGPHLVLEDRQSEALLSQVRQILSNTAPGQTRPVVLTSTDIRRFVRGF
FTRNGIDVAVLSYQDIASDFTVKPAGSVKFPHGLISGLSE

Specific function: Could be involved in the secretion of an unknown factor [H]

COG id: COG4789

COG function: function code U; Type III secretory pathway, component EscV

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=687, Percent_Identity=31.4410480349345, Blast_Score=316, Evalue=4e-87,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001712
- InterPro:   IPR006302 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 73880; Mature: 73748

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVLRKFINRSPANPDLMVALMLLLAIAMMVMPIPIVVVDALIGFNMGLAILLMMVALY
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VSTPLDLSSLPGIILLSTVFRLALTVATTRLILAEGEAGAIIHTFGDFVISGNIVVGFVI
HCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCHHEECCHHHHHHH
FLVVTMVQFMVLAKGAERVAEVAARFTLDALPGKQMAVDAELRNGHIDANESRRRRAALE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCCCCHHHHHHHHHH
KESQLYGAMDGAMKFVKGDSIAGLVVIFINMLGGISIGLLSKGMSFGDVLHHYTLLTIGD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHH
ALISQIPALLLSITAATVVTRVTGAARVNLGTEIVNQITASKRPVRVAACVLVLMGFVPG
HHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
FPLPVFLVLAAIFAAISFVKGDVVDTTSAGDTQKQTAPAQECPIAFFLAPDLMHAIEQVE
CCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHCCCHHHCCEEEEECHHHHHHHHHHH
LQQEIARVSQLLSADLGIVVPPIPVTVDQQLLESQFRIDIEGVPVEQGVFDPSQLMLKDD
HHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCEEECCCCHHCCCCCHHHHHHHHH
VANIESSGIPYRRDPKTDRLVADQSHAPALKSAGITHYGPGEFLALRLHTALTRFAPRLI
HHHHHCCCCCCCCCCCCCCEECCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GIQETRQLIGRMEKDYSDLVKEVLRTTPIPRIADVLRRLLDEGIPIRHTRLLLEGLAEWS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EREPNVALLTEYIRSGLKRQICHRYANTEGIVPALVVERQSEDVMRNAVRDSAAGPHLVL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCEEE
EDRQSEALLSQVRQILSNTAPGQTRPVVLTSTDIRRFVRGFFTRNGIDVAVLSYQDIASD
ECCHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEEHHHHHCC
FTVKPAGSVKFPHGLISGLSE
CEECCCCCCCCCHHHHCCCCC
>Mature Secondary Structure 
ANVLRKFINRSPANPDLMVALMLLLAIAMMVMPIPIVVVDALIGFNMGLAILLMMVALY
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
VSTPLDLSSLPGIILLSTVFRLALTVATTRLILAEGEAGAIIHTFGDFVISGNIVVGFVI
HCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCHHEECCHHHHHHH
FLVVTMVQFMVLAKGAERVAEVAARFTLDALPGKQMAVDAELRNGHIDANESRRRRAALE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCCCCHHHHHHHHHH
KESQLYGAMDGAMKFVKGDSIAGLVVIFINMLGGISIGLLSKGMSFGDVLHHYTLLTIGD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHH
ALISQIPALLLSITAATVVTRVTGAARVNLGTEIVNQITASKRPVRVAACVLVLMGFVPG
HHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
FPLPVFLVLAAIFAAISFVKGDVVDTTSAGDTQKQTAPAQECPIAFFLAPDLMHAIEQVE
CCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHCCCHHHCCEEEEECHHHHHHHHHHH
LQQEIARVSQLLSADLGIVVPPIPVTVDQQLLESQFRIDIEGVPVEQGVFDPSQLMLKDD
HHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCEEECCCCHHCCCCCHHHHHHHHH
VANIESSGIPYRRDPKTDRLVADQSHAPALKSAGITHYGPGEFLALRLHTALTRFAPRLI
HHHHHCCCCCCCCCCCCCCEECCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GIQETRQLIGRMEKDYSDLVKEVLRTTPIPRIADVLRRLLDEGIPIRHTRLLLEGLAEWS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EREPNVALLTEYIRSGLKRQICHRYANTEGIVPALVVERQSEDVMRNAVRDSAAGPHLVL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCEEE
EDRQSEALLSQVRQILSNTAPGQTRPVVLTSTDIRRFVRGFFTRNGIDVAVLSYQDIASD
ECCHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCEEEEEHHHHHCC
FTVKPAGSVKFPHGLISGLSE
CEECCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]