Click here to switch to the map view.

The map label for this gene is tynA [H]

Identifier: 13475222

GI number: 13475222

Start: 5065927

End: 5067891

Strand: Reverse

Name: tynA [H]

Synonym: mll6250

Alternate gene names: 13475222

Gene position: 5067891-5065927 (Counterclockwise)

Preceding gene: 13475223

Following gene: 13475221

Centisome position: 72.03

GC content: 55.88

Gene sequence:

>1965_bases
ATGAATACGAAGATGACTGTGCCGACGAAAGCGGTATGCGGATGTTCGAAACCCGCCGATGCAACGGCGTCAGCGCATCC
GCTTGATCCGCTTTCAAAGGCCGAACTGCTGAGTGTCTTCGAGATCGTTCGTGACGATGCTGCCTTCGGCAAGGATTTTT
ACTTTGAGACTGTGGAACTACTAGAGCCGGCTAAGGGGAGTGTTCGATCCTTTCGGAGAGGCAATCCGATCTCCAGGAAA
GCGCGCGTGAATCTGTTCCGGATCGATCGCGATGGTGTCTGGCGCCTAGTTGTATCGCTCGACGAAAACAAGGTCGAGAA
GTCGGAGTACCTTGCATCGGCAAAGCCGATGATCCAGCTCGAACAGTTCACTGCCATCGAAGATGCAGTCAGGGACGCTC
CCGATTTTATCGCCGCCTGCAGTCGGCGGGGTATCAACGATATGAGCCAGGTCTGCATTGATCCGTGGTCGGCTGGAAAT
TTCGGCGTTCCGGATGAGGAGGGCCGGTATATCGCCCACGTCTTCGCCTGGTTGCGCCTGCGGGAGAACGAAAATTTCTA
TGCGCATCCCATCGGGGGACTGAACGCAATCGTCGATATCAGGACCAACCGTGTTCTGCGTGTCGACGATCACGAGATTA
TTCCAATTCCGATGAAGGAGGCCAACTACGAAGCCGAGTTCATTAAGGAACCGCGTCAGCCTTACAAGCCCCTCAATATC
GCGCAACCCGAGGGTGTTTCATTCAACCTGGACGGCCATCAGCTAAGCTGGGACAAGTGGGCGTTTCGTGTTGGCTTCAA
TGCCAGGGAAGGCTTGACGCTTCACGACATCAGCTACGATGGGCGGCCGGTCGTTTATCGCGCATCGCTTGTCGAGATGG
TCGTCCCCTACGGCACGCCTGATCGTGGCCATTTCCGCAAGAATGTTTTCGACATCGGGGAATACGGCATTGGCAAGCTG
GCGAACTCTTTGAAGCTTGGTTGCGACTGCCTTGGAGCGATCCAGTACCTCGATGCAAATCTTGCAACGATGACCGGCGA
TGTCGTGACGATCGAGAATGCCATCTGCATTCATGAAGAGGATGCCGGTCTTCTCTGGAAGCACTGGGACTTCCGATCCA
ACCACGTTGAATCTCGTCGGGCTCGCAAGTTCGTTGTCTCGTGTATTTGCACAGTGGCAAACTATGAATATGGCATTTTC
TGGTACCTCCACACGGATGGCGCGATCGAATTTGAGCTGAAGGCAACCGGCATCATCAACACGACGGCTTGCCAGCCAGG
AAAGCCTGGGCGCTATGGCAAAGAGGTCTCGCCTGGCGTTCTCGGACATATCCACCAGCATATCTTCTGCGCCCGGCTGG
ACATGAGCGTCGACGGCGATCGCAATAGCGTTGTCGAGCTAAACACCTATGCCGCGCCTGAGGGTCCGGACAATCCACAC
GGCAATGCCTTTTACGAAGAAGAGACCGTGCTGCCTTCCGAACTCCAGGCCTGCCGGCGGGCAAACCTTGAAACTCATCG
GGCATGGAAAATCGCAAGCGCCGACCGGAAGAACCATGTTGGCGAGCCTACTGCTTATAAGCTAGAGGCCACTCATCCCG
TAACGCCATACGTTGCGGCACACTCACCGTCGGGCCGTCGTTCAACCTTTACCAGCAATCATTTGTGGGTGACGGCTTTT
GATCCCGAGGAACGCTATCCAGCTGGTGAATACATGAACCATTCTGACGGCTCCGGCGGTGTCGCGGACTTCGTGAAGAA
TGACAGGCCGTTGGTCGATGAGGATCTTGTCCTCTGGCACACCTTCGGAGTGCATCACCAGGTTCGGCCAGAGGACTTTC
CTGTCCAGCCTTGCATCTTCACCGGCTTCAAGCTGATGCCGAGCGGCTTCTTCGATCAGAACCCTGGCATCGATCTGGTG
GGCGAGACCAACGCTGCCAGCTGCCACGCGAGCGCCGACCGCTAA

Upstream 100 bases:

>100_bases
TGTCTGGTCTTATAAATCTGATACATTGTCAAGGATATGGCTTTGATCGGATAGATCGCGGACGTATTGTCGGCTAGCTA
AAGAGAGGAAACATTTCAAA

Downstream 100 bases:

>100_bases
AGTCGGCTGCGCCAGCGGGGAAGCGAGACCCGCTTCCCCGTGTTCCCGAGGATAATGCCATGAGGAATGCCCAAGGCCTT
CATTTTGGGGCAATGGCTTC

Product: tyramine oxidase

Products: NA

Alternate protein names: Copper amine oxidase; MAOXI [H]

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MNTKMTVPTKAVCGCSKPADATASAHPLDPLSKAELLSVFEIVRDDAAFGKDFYFETVELLEPAKGSVRSFRRGNPISRK
ARVNLFRIDRDGVWRLVVSLDENKVEKSEYLASAKPMIQLEQFTAIEDAVRDAPDFIAACSRRGINDMSQVCIDPWSAGN
FGVPDEEGRYIAHVFAWLRLRENENFYAHPIGGLNAIVDIRTNRVLRVDDHEIIPIPMKEANYEAEFIKEPRQPYKPLNI
AQPEGVSFNLDGHQLSWDKWAFRVGFNAREGLTLHDISYDGRPVVYRASLVEMVVPYGTPDRGHFRKNVFDIGEYGIGKL
ANSLKLGCDCLGAIQYLDANLATMTGDVVTIENAICIHEEDAGLLWKHWDFRSNHVESRRARKFVVSCICTVANYEYGIF
WYLHTDGAIEFELKATGIINTTACQPGKPGRYGKEVSPGVLGHIHQHIFCARLDMSVDGDRNSVVELNTYAAPEGPDNPH
GNAFYEEETVLPSELQACRRANLETHRAWKIASADRKNHVGEPTAYKLEATHPVTPYVAAHSPSGRRSTFTSNHLWVTAF
DPEERYPAGEYMNHSDGSGGVADFVKNDRPLVDEDLVLWHTFGVHHQVRPEDFPVQPCIFTGFKLMPSGFFDQNPGIDLV
GETNAASCHASADR

Sequences:

>Translated_654_residues
MNTKMTVPTKAVCGCSKPADATASAHPLDPLSKAELLSVFEIVRDDAAFGKDFYFETVELLEPAKGSVRSFRRGNPISRK
ARVNLFRIDRDGVWRLVVSLDENKVEKSEYLASAKPMIQLEQFTAIEDAVRDAPDFIAACSRRGINDMSQVCIDPWSAGN
FGVPDEEGRYIAHVFAWLRLRENENFYAHPIGGLNAIVDIRTNRVLRVDDHEIIPIPMKEANYEAEFIKEPRQPYKPLNI
AQPEGVSFNLDGHQLSWDKWAFRVGFNAREGLTLHDISYDGRPVVYRASLVEMVVPYGTPDRGHFRKNVFDIGEYGIGKL
ANSLKLGCDCLGAIQYLDANLATMTGDVVTIENAICIHEEDAGLLWKHWDFRSNHVESRRARKFVVSCICTVANYEYGIF
WYLHTDGAIEFELKATGIINTTACQPGKPGRYGKEVSPGVLGHIHQHIFCARLDMSVDGDRNSVVELNTYAAPEGPDNPH
GNAFYEEETVLPSELQACRRANLETHRAWKIASADRKNHVGEPTAYKLEATHPVTPYVAAHSPSGRRSTFTSNHLWVTAF
DPEERYPAGEYMNHSDGSGGVADFVKNDRPLVDEDLVLWHTFGVHHQVRPEDFPVQPCIFTGFKLMPSGFFDQNPGIDLV
GETNAASCHASADR
>Mature_654_residues
MNTKMTVPTKAVCGCSKPADATASAHPLDPLSKAELLSVFEIVRDDAAFGKDFYFETVELLEPAKGSVRSFRRGNPISRK
ARVNLFRIDRDGVWRLVVSLDENKVEKSEYLASAKPMIQLEQFTAIEDAVRDAPDFIAACSRRGINDMSQVCIDPWSAGN
FGVPDEEGRYIAHVFAWLRLRENENFYAHPIGGLNAIVDIRTNRVLRVDDHEIIPIPMKEANYEAEFIKEPRQPYKPLNI
AQPEGVSFNLDGHQLSWDKWAFRVGFNAREGLTLHDISYDGRPVVYRASLVEMVVPYGTPDRGHFRKNVFDIGEYGIGKL
ANSLKLGCDCLGAIQYLDANLATMTGDVVTIENAICIHEEDAGLLWKHWDFRSNHVESRRARKFVVSCICTVANYEYGIF
WYLHTDGAIEFELKATGIINTTACQPGKPGRYGKEVSPGVLGHIHQHIFCARLDMSVDGDRNSVVELNTYAAPEGPDNPH
GNAFYEEETVLPSELQACRRANLETHRAWKIASADRKNHVGEPTAYKLEATHPVTPYVAAHSPSGRRSTFTSNHLWVTAF
DPEERYPAGEYMNHSDGSGGVADFVKNDRPLVDEDLVLWHTFGVHHQVRPEDFPVQPCIFTGFKLMPSGFFDQNPGIDLV
GETNAASCHASADR

Specific function: The exact function of maoXI is not known [H]

COG id: COG3733

COG function: function code Q; Cu2+-containing amine oxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the copper/topaquinone oxidase family [H]

Homologues:

Organism=Homo sapiens, GI60498984, Length=438, Percent_Identity=27.8538812785388, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI4502119, Length=422, Percent_Identity=28.1990521327014, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI60498982, Length=436, Percent_Identity=27.0642201834862, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI73486661, Length=411, Percent_Identity=25.0608272506083, Blast_Score=118, Evalue=2e-26,
Organism=Escherichia coli, GI1787651, Length=647, Percent_Identity=29.3663060278207, Blast_Score=315, Evalue=4e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000269
- InterPro:   IPR015798
- InterPro:   IPR016182
- InterPro:   IPR015800
- InterPro:   IPR015801
- InterPro:   IPR015802 [H]

Pfam domain/function: PF01179 Cu_amine_oxid; PF02727 Cu_amine_oxidN2; PF02728 Cu_amine_oxidN3 [H]

EC number: =1.4.3.21 [H]

Molecular weight: Translated: 73154; Mature: 73154

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKMTVPTKAVCGCSKPADATASAHPLDPLSKAELLSVFEIVRDDAAFGKDFYFETVEL
CCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LEPAKGSVRSFRRGNPISRKARVNLFRIDRDGVWRLVVSLDENKVEKSEYLASAKPMIQL
HCCCCHHHHHHHCCCCCCCCEEEEEEEECCCCEEEEEEEECCCHHHHHHHHHCCCCCEEH
EQFTAIEDAVRDAPDFIAACSRRGINDMSQVCIDPWSAGNFGVPDEEGRYIAHVFAWLRL
HHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHE
RENENFYAHPIGGLNAIVDIRTNRVLRVDDHEIIPIPMKEANYEAEFIKEPRQPYKPLNI
ECCCCEEECCCCCCEEEEEECCCEEEEECCCEEEECCHHHCCCCHHHHHCCCCCCCCCCC
AQPEGVSFNLDGHQLSWDKWAFRVGFNAREGLTLHDISYDGRPVVYRASLVEMVVPYGTP
CCCCCCEEECCCCEECCCCEEEEECCCCCCCCEEEECCCCCCCEEEHHHHHHHHCCCCCC
DRGHFRKNVFDIGEYGIGKLANSLKLGCDCLGAIQYLDANLATMTGDVVTIENAICIHEE
CCCCHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHCCCHHHCCCCEEEEECEEEEEEC
DAGLLWKHWDFRSNHVESRRARKFVVSCICTVANYEYGIFWYLHTDGAIEFELKATGIIN
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEEECCEEE
TTACQPGKPGRYGKEVSPGVLGHIHQHIFCARLDMSVDGDRNSVVELNTYAAPEGPDNPH
ECCCCCCCCCCCCCCCCCHHHHHHHHHEEEEEECCEECCCCCCEEEEEEEECCCCCCCCC
GNAFYEEETVLPSELQACRRANLETHRAWKIASADRKNHVGEPTAYKLEATHPVTPYVAA
CCCEECCCCCCHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCCEEEEECCCCCCCEEEE
HSPSGRRSTFTSNHLWVTAFDPEERYPAGEYMNHSDGSGGVADFVKNDRPLVDEDLVLWH
CCCCCCCCCEECCEEEEEEECCHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEE
TFGVHHQVRPEDFPVQPCIFTGFKLMPSGFFDQNPGIDLVGETNAASCHASADR
EECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNTKMTVPTKAVCGCSKPADATASAHPLDPLSKAELLSVFEIVRDDAAFGKDFYFETVEL
CCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LEPAKGSVRSFRRGNPISRKARVNLFRIDRDGVWRLVVSLDENKVEKSEYLASAKPMIQL
HCCCCHHHHHHHCCCCCCCCEEEEEEEECCCCEEEEEEEECCCHHHHHHHHHCCCCCEEH
EQFTAIEDAVRDAPDFIAACSRRGINDMSQVCIDPWSAGNFGVPDEEGRYIAHVFAWLRL
HHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHE
RENENFYAHPIGGLNAIVDIRTNRVLRVDDHEIIPIPMKEANYEAEFIKEPRQPYKPLNI
ECCCCEEECCCCCCEEEEEECCCEEEEECCCEEEECCHHHCCCCHHHHHCCCCCCCCCCC
AQPEGVSFNLDGHQLSWDKWAFRVGFNAREGLTLHDISYDGRPVVYRASLVEMVVPYGTP
CCCCCCEEECCCCEECCCCEEEEECCCCCCCCEEEECCCCCCCEEEHHHHHHHHCCCCCC
DRGHFRKNVFDIGEYGIGKLANSLKLGCDCLGAIQYLDANLATMTGDVVTIENAICIHEE
CCCCHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHCCCHHHCCCCEEEEECEEEEEEC
DAGLLWKHWDFRSNHVESRRARKFVVSCICTVANYEYGIFWYLHTDGAIEFELKATGIIN
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEEECCEEE
TTACQPGKPGRYGKEVSPGVLGHIHQHIFCARLDMSVDGDRNSVVELNTYAAPEGPDNPH
ECCCCCCCCCCCCCCCCCHHHHHHHHHEEEEEECCEECCCCCCEEEEEEEECCCCCCCCC
GNAFYEEETVLPSELQACRRANLETHRAWKIASADRKNHVGEPTAYKLEATHPVTPYVAA
CCCEECCCCCCHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCCEEEEECCCCCCCEEEE
HSPSGRRSTFTSNHLWVTAFDPEERYPAGEYMNHSDGSGGVADFVKNDRPLVDEDLVLWH
CCCCCCCCCEECCEEEEEEECCHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEE
TFGVHHQVRPEDFPVQPCIFTGFKLMPSGFFDQNPGIDLVGETNAASCHASADR
EECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8366046 [H]