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The map label for this gene is potH [H]

Identifier: 13475074

GI number: 13475074

Start: 4914291

End: 4916069

Strand: Direct

Name: potH [H]

Synonym: mlr6080

Alternate gene names: 13475074

Gene position: 4914291-4916069 (Clockwise)

Preceding gene: 13475073

Following gene: 13475075

Centisome position: 69.84

GC content: 58.8

Gene sequence:

>1779_bases
ATGCAAATGCTTCAGAAATTCGGCCGAATGCCCATTGCACTCACCGTGCCGGCACTCGCCATCCTGCTCGTCGTTTTCGG
TGTACCGATCGTTCAGCTCTTCCTGACTAGCCTCAATGCGCCGGACCTTTCGATGGTCAACTATCGTGCATTTTTCGGTC
GGTCGGCGAATGTCCGCGTGCTCTACCAGACGATCGAGATCAGCTTGGTGGCCACAGCGATTTGCCTCATCATCGGCTAT
CCCGCGGCCTATCTGATCGTGACTGCCTCCAAGCGTTTGCGCATGACGCTCATCGTGCTCGTCGTTATCCCCTATCTCAC
CAGCGGATTGGCGCGCACGTATGCCTGGATCATAATTCTTGGCGATGGCGGCCTGATCAACAATCTTTTGCTCGAACTCG
GTCTGATCTCGAGCCCGCTGCCGCTCATCTACAACCGTATGGCCGTCTATATCGCCATGGTGCACATTATGCTGCCTATG
ATGATCCTGCCTCTGGTCAGCGTCATGATGGGTATTGACAGGTCCCTGATGGCCGCAGCGCGCAGCATGGGCGCGGGGCC
GTTCACTGCGTTCTGGCGCGTGTTCTTTCCGCTCAGCTTGCCGGGCGTGCGCAGTGGCTCCCTGTTGGTCTTTGTGATCT
GCCTCGGCTTTTACATTACGCCGGCCGCCGTCGGCGGCTTGCGAGATGCCATGCTGTCAACCTTCATCGCGTCGCAGGTC
TCGACCGGCTTTGATATGGCACCCATTGCAGCCTCGTCCTTCATTCTCCTGGCGATCGCCGTGGCCGTGCTCTCCTTGCT
TGGGCTCGATCTTTCGGGTACCCAGGGGCGCGCGGTACAAGCAGTGCGGAAGTCTCGGCCAAGCCGGCGGCCCTCATTCG
GCACAATCAAAAGCTATCTCCGCGAACTTCCCGTTTCGTCACGTGCGAAGCGATGGACGGTCCAGCTCTATCAAGCCCGG
GGCGACAGCCAATGGTCGAAAATCGTTGGACCGGTGTTCGTCGTTGTGGTCATGTTCTACCTGCTGTTTCCCGAAGCCGT
CGTGATCATCATGTCGTTCAGCGCCGGGTCGGTTCTGGAATTTCCACCCTCGGGCCTTTCGCTGCGGTGGTACCGTTCCT
TCTTCGACGATCCCTCCTGGTATGGAGCTGCCTGGACCAGCATTCAGATCGGCGTTGCAGTCGCCGTCCTCTCGACCGTC
GTCGGCACGCTCGCGGCCTACGGCATCAGCCGCGCCCGCCCGCAACTGCGCAGCTCTCTGACAATGGCGATCCTGACGCC
GATTACCATTCCGGTTATCGTTGTGGGCGTAGCGACCTACTTCGGGCTGGCCAATCTCGGACTGATAGGCTCGAAGACAG
GTATCGTCCTGGCACACAGCATCGGCGCCATAGGCTATGTCGTCGTGATAGTGTCAGCGACACTGGCAAATTTTGACCGT
ACGCTAGAGCAGGCAGCAATGAGCATGCGGGCTGGGCCGCTGCAAACCTTCATGAGGGTGACCTTGCCCTTGATACGGCC
GGGCATCATCGGCGGCGCGGTGTTCGCCTTTATTCACTCCTTTGACGAGGTCGTCGTCACCTCATTTGTCGGCGGATTCT
CAATGTACACCCTGCCGCTGAAGATGTGGGAAAATATACGGAACCAGATCGACCCGACGGTCGCCGCAGTGGCGTCGCTA
TTGACCCTTCTCCCTGTGATCTGGTTGGTAGCCCTATACGTCACGTGGTGGCGATCTAGGCGAACGAGTCACCGCGTGCT
TCCAGAGGCCCAAGTTTGA

Upstream 100 bases:

>100_bases
TCGGGGCAGCAGATCTTCCAACCCGGCGACACAGTGCGGCTTGATTGGCTGCGGTCCGACGTTCGCTTCGTAGCGGCGTG
AATCCCCGGGAGATGGGCGA

Downstream 100 bases:

>100_bases
GGTCATGCGGAGAGGATCCGGCCAACCTTGTGACGTGATAGGGCTCAAGGCTTTCTGCATTGTTCGCGCCGCACCATGAA
CTGAGGTCGGCTGACCAAAC

Product: ABC transporter, permease

Products: ADP; phosphate; putrescine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MQMLQKFGRMPIALTVPALAILLVVFGVPIVQLFLTSLNAPDLSMVNYRAFFGRSANVRVLYQTIEISLVATAICLIIGY
PAAYLIVTASKRLRMTLIVLVVIPYLTSGLARTYAWIIILGDGGLINNLLLELGLISSPLPLIYNRMAVYIAMVHIMLPM
MILPLVSVMMGIDRSLMAAARSMGAGPFTAFWRVFFPLSLPGVRSGSLLVFVICLGFYITPAAVGGLRDAMLSTFIASQV
STGFDMAPIAASSFILLAIAVAVLSLLGLDLSGTQGRAVQAVRKSRPSRRPSFGTIKSYLRELPVSSRAKRWTVQLYQAR
GDSQWSKIVGPVFVVVVMFYLLFPEAVVIIMSFSAGSVLEFPPSGLSLRWYRSFFDDPSWYGAAWTSIQIGVAVAVLSTV
VGTLAAYGISRARPQLRSSLTMAILTPITIPVIVVGVATYFGLANLGLIGSKTGIVLAHSIGAIGYVVVIVSATLANFDR
TLEQAAMSMRAGPLQTFMRVTLPLIRPGIIGGAVFAFIHSFDEVVVTSFVGGFSMYTLPLKMWENIRNQIDPTVAAVASL
LTLLPVIWLVALYVTWWRSRRTSHRVLPEAQV

Sequences:

>Translated_592_residues
MQMLQKFGRMPIALTVPALAILLVVFGVPIVQLFLTSLNAPDLSMVNYRAFFGRSANVRVLYQTIEISLVATAICLIIGY
PAAYLIVTASKRLRMTLIVLVVIPYLTSGLARTYAWIIILGDGGLINNLLLELGLISSPLPLIYNRMAVYIAMVHIMLPM
MILPLVSVMMGIDRSLMAAARSMGAGPFTAFWRVFFPLSLPGVRSGSLLVFVICLGFYITPAAVGGLRDAMLSTFIASQV
STGFDMAPIAASSFILLAIAVAVLSLLGLDLSGTQGRAVQAVRKSRPSRRPSFGTIKSYLRELPVSSRAKRWTVQLYQAR
GDSQWSKIVGPVFVVVVMFYLLFPEAVVIIMSFSAGSVLEFPPSGLSLRWYRSFFDDPSWYGAAWTSIQIGVAVAVLSTV
VGTLAAYGISRARPQLRSSLTMAILTPITIPVIVVGVATYFGLANLGLIGSKTGIVLAHSIGAIGYVVVIVSATLANFDR
TLEQAAMSMRAGPLQTFMRVTLPLIRPGIIGGAVFAFIHSFDEVVVTSFVGGFSMYTLPLKMWENIRNQIDPTVAAVASL
LTLLPVIWLVALYVTWWRSRRTSHRVLPEAQV
>Mature_592_residues
MQMLQKFGRMPIALTVPALAILLVVFGVPIVQLFLTSLNAPDLSMVNYRAFFGRSANVRVLYQTIEISLVATAICLIIGY
PAAYLIVTASKRLRMTLIVLVVIPYLTSGLARTYAWIIILGDGGLINNLLLELGLISSPLPLIYNRMAVYIAMVHIMLPM
MILPLVSVMMGIDRSLMAAARSMGAGPFTAFWRVFFPLSLPGVRSGSLLVFVICLGFYITPAAVGGLRDAMLSTFIASQV
STGFDMAPIAASSFILLAIAVAVLSLLGLDLSGTQGRAVQAVRKSRPSRRPSFGTIKSYLRELPVSSRAKRWTVQLYQAR
GDSQWSKIVGPVFVVVVMFYLLFPEAVVIIMSFSAGSVLEFPPSGLSLRWYRSFFDDPSWYGAAWTSIQIGVAVAVLSTV
VGTLAAYGISRARPQLRSSLTMAILTPITIPVIVVGVATYFGLANLGLIGSKTGIVLAHSIGAIGYVVVIVSATLANFDR
TLEQAAMSMRAGPLQTFMRVTLPLIRPGIIGGAVFAFIHSFDEVVVTSFVGGFSMYTLPLKMWENIRNQIDPTVAAVASL
LTLLPVIWLVALYVTWWRSRRTSHRVLPEAQV

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787080, Length=195, Percent_Identity=35.8974358974359, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI1787369, Length=250, Percent_Identity=31.2, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1787081, Length=263, Percent_Identity=28.8973384030418, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1787368, Length=208, Percent_Identity=28.3653846153846, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1787713, Length=199, Percent_Identity=29.1457286432161, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1787714, Length=253, Percent_Identity=30.4347826086957, Blast_Score=76, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 64271; Mature: 64271

Theoretical pI: Translated: 10.76; Mature: 10.76

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMLQKFGRMPIALTVPALAILLVVFGVPIVQLFLTSLNAPDLSMVNYRAFFGRSANVRV
CCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEE
LYQTIEISLVATAICLIIGYPAAYLIVTASKRLRMTLIVLVVIPYLTSGLARTYAWIIIL
EHHHHHHHHHHHHHHHHHCCCHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
GDGGLINNLLLELGLISSPLPLIYNRMAVYIAMVHIMLPMMILPLVSVMMGIDRSLMAAA
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RSMGAGPFTAFWRVFFPLSLPGVRSGSLLVFVICLGFYITPAAVGGLRDAMLSTFIASQV
HHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STGFDMAPIAASSFILLAIAVAVLSLLGLDLSGTQGRAVQAVRKSRPSRRPSFGTIKSYL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHH
RELPVSSRAKRWTVQLYQARGDSQWSKIVGPVFVVVVMFYLLFPEAVVIIMSFSAGSVLE
HHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEE
FPPSGLSLRWYRSFFDDPSWYGAAWTSIQIGVAVAVLSTVVGTLAAYGISRARPQLRSSL
CCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
TMAILTPITIPVIVVGVATYFGLANLGLIGSKTGIVLAHSIGAIGYVVVIVSATLANFDR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
TLEQAAMSMRAGPLQTFMRVTLPLIRPGIIGGAVFAFIHSFDEVVVTSFVGGFSMYTLPL
HHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KMWENIRNQIDPTVAAVASLLTLLPVIWLVALYVTWWRSRRTSHRVLPEAQV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQMLQKFGRMPIALTVPALAILLVVFGVPIVQLFLTSLNAPDLSMVNYRAFFGRSANVRV
CCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEE
LYQTIEISLVATAICLIIGYPAAYLIVTASKRLRMTLIVLVVIPYLTSGLARTYAWIIIL
EHHHHHHHHHHHHHHHHHCCCHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
GDGGLINNLLLELGLISSPLPLIYNRMAVYIAMVHIMLPMMILPLVSVMMGIDRSLMAAA
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RSMGAGPFTAFWRVFFPLSLPGVRSGSLLVFVICLGFYITPAAVGGLRDAMLSTFIASQV
HHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STGFDMAPIAASSFILLAIAVAVLSLLGLDLSGTQGRAVQAVRKSRPSRRPSFGTIKSYL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHH
RELPVSSRAKRWTVQLYQARGDSQWSKIVGPVFVVVVMFYLLFPEAVVIIMSFSAGSVLE
HHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEE
FPPSGLSLRWYRSFFDDPSWYGAAWTSIQIGVAVAVLSTVVGTLAAYGISRARPQLRSSL
CCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
TMAILTPITIPVIVVGVATYFGLANLGLIGSKTGIVLAHSIGAIGYVVVIVSATLANFDR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
TLEQAAMSMRAGPLQTFMRVTLPLIRPGIIGGAVFAFIHSFDEVVVTSFVGGFSMYTLPL
HHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KMWENIRNQIDPTVAAVASLLTLLPVIWLVALYVTWWRSRRTSHRVLPEAQV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; putrescine [Periplasm]; H2O [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8416922; 8905232; 9278503 [H]