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The map label for this gene is fixC [H]

Identifier: 13474880

GI number: 13474880

Start: 4732602

End: 4733909

Strand: Reverse

Name: fixC [H]

Synonym: mll5860

Alternate gene names: 13474880

Gene position: 4733909-4732602 (Counterclockwise)

Preceding gene: 13474881

Following gene: 13474879

Centisome position: 67.28

GC content: 60.32

Gene sequence:

>1308_bases
ATGATCGAGGAAGAATTCGACGCCATCGTCGTCGGGGCCGGTATGTCCGGAAACGCGGCCGCCTACACCATGGCAAGCCA
GGGCCTGACGGTGCTGCAGTTGGAGCGCGGCGAGTATCCGGGCTCCAAGAATGTCCAGGGCGCCATCATGTACGCCGACA
TGTTGGAGCAAATCATTCCGGATTTCCGGGATGATGCGCCTCTCGAGCGGCATCTGGTCGAGCAGCGATTCTGGGTGATG
GACGACACCTCCCACACCGGGATGCAGTATCGATCGGACGATTTCAACGAGGCGAAGCCCAATCGCTACACGATCATCCG
CGCCCAATTCGACAAGTGGTTTTCGCGCAAGGTGCGCCAGGCCGGCGCGACGGTGCTGTGCGAGACGACGGTGACCGAAC
TTATCCGCAATGCCAGCGGCAAGGTGATCGGCGTGCGCACCGACCGGGCTGGCGGGCCGATCTACGCGGACGTCGTCGTG
CTCGCAGAAGGTGTCAACGGACTGCTCGGTACACGGGCCGGCCTGCGCAAGATGCCGAAGCCAGAAAGCGTGGCGCTCGC
TGTCAAGGAAATGCATTTCCTACCCGATGAGGTCATTGAGCAGCGGTTCGGCCTCCAGGGCGACGAAGGCTGCGTGATCG
AAGCGGCGGGCACGATTTCCCGCAGCATGGCCGGACTGGCCTTCCTCTACACCAACAAGGAGTCGATCTCTCTCGGCATC
GGCTGCCTCGTCTCCGATTTCGCCCAGACAATGGAGAGCCCTTACGTCCTCCTCGACAACTTCAAAAACCATCCTTCGAT
CCGGCCGCTGATCGCGGGCTCGGAAGTCAAGGAGTATTCCGCGCATCTCATTCCCGAAGGTGGCTACAAGGCAATTCCGC
AGCTCTTCGGCGACGGTTGGGTGGCGGTCGGTGATGCCGCCCAACTGAACAACGCTATTCACCGCGAGGGTTCGAACCTT
GCCATGACTTCCGGTCGCATCGCGGGCGAGGCAATCATTGAGATCAAGGGCCGCAACCAGCCGATGATCAGGAGGAACCT
CGCCCTCTACAAGACCATGCTGGACAAGTCCTTCGTAGTCAAAGACCTGATGAAATATAAGGACATGCCGGCCCTGATAC
ACACCAATTCCCGCAATTTCTTCATGACTTACCCGCAGTTGATGTCGCAGGCCGCGCAGAACTTCATGCGGGTCGACGGA
ACCCCGAAAATCGAGAAGGAAAAGGCGACCACTGCTGCCTTCATCAAGGCGCGTTCGCGCTGGGGGCTGATCAGCGATGT
GGTCCGCCTGGCACTCGCCTGGCGCTGA

Upstream 100 bases:

>100_bases
TCACCGACGCAATCCGTTTCCTGCCGGCATTGACGGAAGCTTTCACCCGGCGGCTGTCGCCGCACAGCCACGACAAGCTT
GCGAGCTAAGGGAGAGGGCC

Downstream 100 bases:

>100_bases
AGGAGAAACAGGATGACGATGGCCGTGACGAAGTTACGTGTCGAGGAGAAGCTTTATCAGAACCGCTATCTGGTCGATCC
GGGCCGCCCGCATATCAAAG

Product: nitrogen fixation protein,fixC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MIEEEFDAIVVGAGMSGNAAAYTMASQGLTVLQLERGEYPGSKNVQGAIMYADMLEQIIPDFRDDAPLERHLVEQRFWVM
DDTSHTGMQYRSDDFNEAKPNRYTIIRAQFDKWFSRKVRQAGATVLCETTVTELIRNASGKVIGVRTDRAGGPIYADVVV
LAEGVNGLLGTRAGLRKMPKPESVALAVKEMHFLPDEVIEQRFGLQGDEGCVIEAAGTISRSMAGLAFLYTNKESISLGI
GCLVSDFAQTMESPYVLLDNFKNHPSIRPLIAGSEVKEYSAHLIPEGGYKAIPQLFGDGWVAVGDAAQLNNAIHREGSNL
AMTSGRIAGEAIIEIKGRNQPMIRRNLALYKTMLDKSFVVKDLMKYKDMPALIHTNSRNFFMTYPQLMSQAAQNFMRVDG
TPKIEKEKATTAAFIKARSRWGLISDVVRLALAWR

Sequences:

>Translated_435_residues
MIEEEFDAIVVGAGMSGNAAAYTMASQGLTVLQLERGEYPGSKNVQGAIMYADMLEQIIPDFRDDAPLERHLVEQRFWVM
DDTSHTGMQYRSDDFNEAKPNRYTIIRAQFDKWFSRKVRQAGATVLCETTVTELIRNASGKVIGVRTDRAGGPIYADVVV
LAEGVNGLLGTRAGLRKMPKPESVALAVKEMHFLPDEVIEQRFGLQGDEGCVIEAAGTISRSMAGLAFLYTNKESISLGI
GCLVSDFAQTMESPYVLLDNFKNHPSIRPLIAGSEVKEYSAHLIPEGGYKAIPQLFGDGWVAVGDAAQLNNAIHREGSNL
AMTSGRIAGEAIIEIKGRNQPMIRRNLALYKTMLDKSFVVKDLMKYKDMPALIHTNSRNFFMTYPQLMSQAAQNFMRVDG
TPKIEKEKATTAAFIKARSRWGLISDVVRLALAWR
>Mature_435_residues
MIEEEFDAIVVGAGMSGNAAAYTMASQGLTVLQLERGEYPGSKNVQGAIMYADMLEQIIPDFRDDAPLERHLVEQRFWVM
DDTSHTGMQYRSDDFNEAKPNRYTIIRAQFDKWFSRKVRQAGATVLCETTVTELIRNASGKVIGVRTDRAGGPIYADVVV
LAEGVNGLLGTRAGLRKMPKPESVALAVKEMHFLPDEVIEQRFGLQGDEGCVIEAAGTISRSMAGLAFLYTNKESISLGI
GCLVSDFAQTMESPYVLLDNFKNHPSIRPLIAGSEVKEYSAHLIPEGGYKAIPQLFGDGWVAVGDAAQLNNAIHREGSNL
AMTSGRIAGEAIIEIKGRNQPMIRRNLALYKTMLDKSFVVKDLMKYKDMPALIHTNSRNFFMTYPQLMSQAAQNFMRVDG
TPKIEKEKATTAAFIKARSRWGLISDVVRLALAWR

Specific function: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from fixA/fixB and reduces a quinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=402, Percent_Identity=24.6268656716418, Blast_Score=107, Evalue=3e-23,
Organism=Escherichia coli, GI1786227, Length=411, Percent_Identity=37.2262773722628, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI1787991, Length=406, Percent_Identity=39.1625615763547, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI87082155, Length=434, Percent_Identity=34.1013824884793, Blast_Score=226, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI25144720, Length=397, Percent_Identity=22.9219143576826, Blast_Score=99, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6324932, Length=414, Percent_Identity=25.3623188405797, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24652256, Length=423, Percent_Identity=24.5862884160757, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002218 [H]

Pfam domain/function: PF01134 GIDA [H]

EC number: 1.5.5.-

Molecular weight: Translated: 48142; Mature: 48142

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEEEFDAIVVGAGMSGNAAAYTMASQGLTVLQLERGEYPGSKNVQGAIMYADMLEQIIP
CCCCCCCEEEEECCCCCCCEEEEEHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCC
DFRDDAPLERHLVEQRFWVMDDTSHTGMQYRSDDFNEAKPNRYTIIRAQFDKWFSRKVRQ
CCCCCCCHHHHHHHHHHEEEECCCCCCCEECCCCCCCCCCCEEEEEEEHHHHHHHHHHHH
AGATVLCETTVTELIRNASGKVIGVRTDRAGGPIYADVVVLAEGVNGLLGTRAGLRKMPK
CCCEEEEHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHCCHHHHCCCC
PESVALAVKEMHFLPDEVIEQRFGLQGDEGCVIEAAGTISRSMAGLAFLYTNKESISLGI
CHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCHHHHHHCCEEEEEECCCCEEHHH
GCLVSDFAQTMESPYVLLDNFKNHPSIRPLIAGSEVKEYSAHLIPEGGYKAIPQLFGDGW
HHHHHHHHHHHCCCEEEEECCCCCCCCCEEECCCHHHHHHHHCCCCCCHHHHHHHHCCCC
VAVGDAAQLNNAIHREGSNLAMTSGRIAGEAIIEIKGRNQPMIRRNLALYKTMLDKSFVV
EEECCHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
KDLMKYKDMPALIHTNSRNFFMTYPQLMSQAAQNFMRVDGTPKIEKEKATTAAFIKARSR
HHHHHHCCCCEEEEECCCCEEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
WGLISDVVRLALAWR
CCHHHHHHHHHHCCC
>Mature Secondary Structure
MIEEEFDAIVVGAGMSGNAAAYTMASQGLTVLQLERGEYPGSKNVQGAIMYADMLEQIIP
CCCCCCCEEEEECCCCCCCEEEEEHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCC
DFRDDAPLERHLVEQRFWVMDDTSHTGMQYRSDDFNEAKPNRYTIIRAQFDKWFSRKVRQ
CCCCCCCHHHHHHHHHHEEEECCCCCCCEECCCCCCCCCCCEEEEEEEHHHHHHHHHHHH
AGATVLCETTVTELIRNASGKVIGVRTDRAGGPIYADVVVLAEGVNGLLGTRAGLRKMPK
CCCEEEEHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHCCHHHHCCCC
PESVALAVKEMHFLPDEVIEQRFGLQGDEGCVIEAAGTISRSMAGLAFLYTNKESISLGI
CHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCHHHHHHCCEEEEEECCCCEEHHH
GCLVSDFAQTMESPYVLLDNFKNHPSIRPLIAGSEVKEYSAHLIPEGGYKAIPQLFGDGW
HHHHHHHHHHHCCCEEEEECCCCCCCCCEEECCCHHHHHHHHCCCCCCHHHHHHHHCCCC
VAVGDAAQLNNAIHREGSNLAMTSGRIAGEAIIEIKGRNQPMIRRNLALYKTMLDKSFVV
EEECCHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
KDLMKYKDMPALIHTNSRNFFMTYPQLMSQAAQNFMRVDGTPKIEKEKATTAAFIKARSR
HHHHHHCCCCEEEEECCCCEEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
WGLISDVVRLALAWR
CCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]