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The map label for this gene is queC1

Identifier: 13474826

GI number: 13474826

Start: 4675394

End: 4676092

Strand: Reverse

Name: queC1

Synonym: mll5798

Alternate gene names: 13474826

Gene position: 4676092-4675394 (Counterclockwise)

Preceding gene: 13474827

Following gene: 13474825

Centisome position: 66.46

GC content: 60.23

Gene sequence:

>699_bases
ATGAATGCCCTCGTCATCTGCTCCGGCGGATTGGACTCTGTTTCGCTCGCTCACAAGGTGGCGACCGAGCAGAAACTCAT
TGGCCTGCTTTCGTTCGATTACGGCCAGAGGCACAAAAAGGAACTCGGCTTTGCCGCTATCTGCGCCAAGCGGCTGGCTG
TTCCGCACCAGATCGTCGATATCCGCGATGTTGGCCGGAACCTGAGCGGCTCGGCGCTGACTGATAATGTGGACGTGCCC
GACGGGCACTATGCCGAAGACTCCATGAGGATCACGGTGGTGCCGAATAGGAACGCCATCATGCTGGCCATCGCCTTCGG
GGTTGCCGCCGCGAAGAAGGCCGATGCGGTGGCCACTGCCGTCCACGGCGGAGATCATTTCATCTATCCCGATTGCCGGC
CCGCTTTTATCGACGCCTTTCAGACGATGCAGAACCATGCCCTCGCAGGCTACGCCGATATCCGCCTGTACGCTCCGTAT
GTGAATATGTCGAAGGCCGACATCGTCAGCGAGGGGGCAAAGTACGCCACACCGTTCGAGGCGACGTGGTCCTGCTACAA
GGGCGGTGCACGTCATTGCGGTCGCTGCGGGACATGCGTCGAACGGCGCGAAGCATTCGATCTGGCCGGCATCACCGACC
CGACAGATTATGAGGACGCAGACTTCTGGCTCCACGCTATCCAGACAAGGAGCGCGTGA

Upstream 100 bases:

>100_bases
ATCGCGTCCACCCCATTCACAAAACCGGCTCCGTGGAGTAGTGGGAACGCAGAGAAATCTCCGGTCGCAGCCTTACCCGG
TCAAAACAAGGATTCAAACC

Downstream 100 bases:

>100_bases
TGTTCCGCATTACCAAAGAGTTCCACTTCTCGGCCTCGCATCAGCTCACCTCCTTGCCACCAGATCATCAGTGCGCACGT
CTGCACGGCCACAACTACAT

Product: succinoglycan biosynthesis regulator (exsB)

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase 1; PreQ(0) synthase 1; Queuosine biosynthesis protein queC 1

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNALVICSGGLDSVSLAHKVATEQKLIGLLSFDYGQRHKKELGFAAICAKRLAVPHQIVDIRDVGRNLSGSALTDNVDVP
DGHYAEDSMRITVVPNRNAIMLAIAFGVAAAKKADAVATAVHGGDHFIYPDCRPAFIDAFQTMQNHALAGYADIRLYAPY
VNMSKADIVSEGAKYATPFEATWSCYKGGARHCGRCGTCVERREAFDLAGITDPTDYEDADFWLHAIQTRSA

Sequences:

>Translated_232_residues
MNALVICSGGLDSVSLAHKVATEQKLIGLLSFDYGQRHKKELGFAAICAKRLAVPHQIVDIRDVGRNLSGSALTDNVDVP
DGHYAEDSMRITVVPNRNAIMLAIAFGVAAAKKADAVATAVHGGDHFIYPDCRPAFIDAFQTMQNHALAGYADIRLYAPY
VNMSKADIVSEGAKYATPFEATWSCYKGGARHCGRCGTCVERREAFDLAGITDPTDYEDADFWLHAIQTRSA
>Mature_232_residues
MNALVICSGGLDSVSLAHKVATEQKLIGLLSFDYGQRHKKELGFAAICAKRLAVPHQIVDIRDVGRNLSGSALTDNVDVP
DGHYAEDSMRITVVPNRNAIMLAIAFGVAAAKKADAVATAVHGGDHFIYPDCRPAFIDAFQTMQNHALAGYADIRLYAPY
VNMSKADIVSEGAKYATPFEATWSCYKGGARHCGRCGTCVERREAFDLAGITDPTDYEDADFWLHAIQTRSA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=220, Percent_Identity=32.7272727272727, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC1_RHILO (Q98AZ0)

Other databases:

- EMBL:   AL672115
- EMBL:   BA000012
- RefSeq:   NP_106396.1
- ProteinModelPortal:   Q98AZ0
- SMR:   Q98AZ0
- GeneID:   1229055
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll5798
- NMPDR:   fig|266835.1.peg.4499
- HOGENOM:   HBG553284
- OMA:   FRICHFR
- ProtClustDB:   CLSK864390
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25125; Mature: 25125

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALVICSGGLDSVSLAHKVATEQKLIGLLSFDYGQRHKKELGFAAICAKRLAVPHQIVD
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCHHEEE
IRDVGRNLSGSALTDNVDVPDGHYAEDSMRITVVPNRNAIMLAIAFGVAAAKKADAVATA
HHHHCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCEEEEEEEHHHHHHHHHHHHEEE
VHGGDHFIYPDCRPAFIDAFQTMQNHALAGYADIRLYAPYVNMSKADIVSEGAKYATPFE
EECCCEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHCCCCCCCCHH
ATWSCYKGGARHCGRCGTCVERREAFDLAGITDPTDYEDADFWLHAIQTRSA
HHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNALVICSGGLDSVSLAHKVATEQKLIGLLSFDYGQRHKKELGFAAICAKRLAVPHQIVD
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCHHEEE
IRDVGRNLSGSALTDNVDVPDGHYAEDSMRITVVPNRNAIMLAIAFGVAAAKKADAVATA
HHHHCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCEEEEEEEHHHHHHHHHHHHEEE
VHGGDHFIYPDCRPAFIDAFQTMQNHALAGYADIRLYAPYVNMSKADIVSEGAKYATPFE
EECCCEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHCCCCCCCCHH
ATWSCYKGGARHCGRCGTCVERREAFDLAGITDPTDYEDADFWLHAIQTRSA
HHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12003951; 11214968