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The map label for this gene is 13474726

Identifier: 13474726

GI number: 13474726

Start: 4565948

End: 4566850

Strand: Reverse

Name: 13474726

Synonym: mll5679

Alternate gene names: NA

Gene position: 4566850-4565948 (Counterclockwise)

Preceding gene: 13474728

Following gene: 13474724

Centisome position: 64.91

GC content: 65.78

Gene sequence:

>903_bases
ATGCCCCTGCAGATCGTCCACCACCCCGACTACGACGCCGGCTTTGCCACCAACCATCGCTTCCCGATGAGCAAATACCC
GCTGCTGATGGAGGCGTTGCGCGCACGCGGCCTGGCCAGTCCTGACGCGCTCAACACTACGGAGCCGGCACCGGCATCAT
GGCTGAAGCTTGCCCATGCGGCCGACTATGTCGATCAGGTCATCAGTTGTTCGGTGCCTGAAAAAATCGAACGCGAGATC
GGCTTTCCGGTCGGCCCGCGCGTTTCGCTGCGTGCGCAGCTTGCCACCGGCGGCACGATACTGGCGGCGCGGCTCGCCTT
GCGCCATGGTATCGCCTGCAACACCGCCGGCGGCAGCCATCATGCGCGGCGCGCGCAAGGCGCCGGCTTCTGCACCTTCA
ACGACGTTGCCGTCGCCTCGCTGGTGCTGCTCGACGAGGGTGCCGCGCAAAACATCCTGGTCGTCGATCTCGACGTGCAT
CAGGGCGACGGTACCGCGGACATTCTAAGCGACGAGCCAGGTGTGTTCACCTTCTCCATGCATGGCGAGCGCAACTATCC
CGTGCGCAAGATCGCCTCCGATCTCGACATCGCGCTTCCCGACGGCACGGGCGATGCCGCCTATCTCCGGAGGCTGGCCA
CGATCCTGCCGGAACTGTCGGCCCGGGCGCGCTGGGACATCGTCTTCTACAATGCCGGCGTCGACGTCCATGCCGAGGAC
CGGCTTGGCAGGCTGGCGCTTTCCAATGGCGGTCTGCGCGCCCGCGACGAAATGGTCATCGGCCATTTTCGTGCGCTGGG
CATTCCAGTCTGCGGCGTCATCGGCGGCGGCTACTCCACGGACGTACCGGCGCTTGCGTCGCGCCACGCCATCCTGTTCG
AGGTCGCCTCGACCTACGCCTAG

Upstream 100 bases:

>100_bases
GTACAGCCGATGTGCCCCATTTTCCGGCCACCGTGCAATCATTCTTCCCGCGATGGCCAACCGAAATCCCGGTCTGGCGC
GAAGCCGCCGGATCCCGTTC

Downstream 100 bases:

>100_bases
ATTGCTCTAAAAGTCACTTCCGATAGTTGGCGATCCTGAGCAGGATGAAAGCCGGCACGACGATCGCGGCACCTAGCAGA
ATGTAGCCGAGGAATCGGTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MPLQIVHHPDYDAGFATNHRFPMSKYPLLMEALRARGLASPDALNTTEPAPASWLKLAHAADYVDQVISCSVPEKIEREI
GFPVGPRVSLRAQLATGGTILAARLALRHGIACNTAGGSHHARRAQGAGFCTFNDVAVASLVLLDEGAAQNILVVDLDVH
QGDGTADILSDEPGVFTFSMHGERNYPVRKIASDLDIALPDGTGDAAYLRRLATILPELSARARWDIVFYNAGVDVHAED
RLGRLALSNGGLRARDEMVIGHFRALGIPVCGVIGGGYSTDVPALASRHAILFEVASTYA

Sequences:

>Translated_300_residues
MPLQIVHHPDYDAGFATNHRFPMSKYPLLMEALRARGLASPDALNTTEPAPASWLKLAHAADYVDQVISCSVPEKIEREI
GFPVGPRVSLRAQLATGGTILAARLALRHGIACNTAGGSHHARRAQGAGFCTFNDVAVASLVLLDEGAAQNILVVDLDVH
QGDGTADILSDEPGVFTFSMHGERNYPVRKIASDLDIALPDGTGDAAYLRRLATILPELSARARWDIVFYNAGVDVHAED
RLGRLALSNGGLRARDEMVIGHFRALGIPVCGVIGGGYSTDVPALASRHAILFEVASTYA
>Mature_299_residues
PLQIVHHPDYDAGFATNHRFPMSKYPLLMEALRARGLASPDALNTTEPAPASWLKLAHAADYVDQVISCSVPEKIEREIG
FPVGPRVSLRAQLATGGTILAARLALRHGIACNTAGGSHHARRAQGAGFCTFNDVAVASLVLLDEGAAQNILVVDLDVHQ
GDGTADILSDEPGVFTFSMHGERNYPVRKIASDLDIALPDGTGDAAYLRRLATILPELSARARWDIVFYNAGVDVHAEDR
LGRLALSNGGLRARDEMVIGHFRALGIPVCGVIGGGYSTDVPALASRHAILFEVASTYA

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=289, Percent_Identity=30.1038062283737, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI209862883, Length=272, Percent_Identity=30.5147058823529, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI13128860, Length=284, Percent_Identity=27.8169014084507, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI13128862, Length=244, Percent_Identity=26.6393442622951, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI293336691, Length=173, Percent_Identity=30.635838150289, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20070354, Length=284, Percent_Identity=29.5774647887324, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI17158039, Length=165, Percent_Identity=32.1212121212121, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI30795202, Length=165, Percent_Identity=32.1212121212121, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI30795204, Length=165, Percent_Identity=32.1212121212121, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI8923769, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI13128864, Length=265, Percent_Identity=29.811320754717, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI153085395, Length=169, Percent_Identity=31.3609467455621, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI226529806, Length=162, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=312, Percent_Identity=33.0128205128205, Blast_Score=144, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17508561, Length=260, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17534739, Length=255, Percent_Identity=27.0588235294118, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561978, Length=263, Percent_Identity=28.5171102661597, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17537347, Length=256, Percent_Identity=31.25, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI193209491, Length=164, Percent_Identity=33.5365853658537, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17540332, Length=189, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193206283, Length=189, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540334, Length=189, Percent_Identity=29.6296296296296, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321244, Length=288, Percent_Identity=28.8194444444444, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323999, Length=291, Percent_Identity=28.1786941580756, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24649807, Length=191, Percent_Identity=38.7434554973822, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24644244, Length=200, Percent_Identity=29, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24657891, Length=201, Percent_Identity=31.3432835820896, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24642144, Length=219, Percent_Identity=28.310502283105, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24642146, Length=219, Percent_Identity=28.310502283105, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24642142, Length=219, Percent_Identity=28.310502283105, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281360899, Length=219, Percent_Identity=28.310502283105, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 32007; Mature: 31876

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLQIVHHPDYDAGFATNHRFPMSKYPLLMEALRARGLASPDALNTTEPAPASWLKLAHA
CCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
ADYVDQVISCSVPEKIEREIGFPVGPRVSLRAQLATGGTILAARLALRHGIACNTAGGSH
HHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEECCCCCC
HARRAQGAGFCTFNDVAVASLVLLDEGAAQNILVVDLDVHQGDGTADILSDEPGVFTFSM
HHHHHCCCCEEEECHHHHHEEEEECCCCCCCEEEEEEEEECCCCCEEECCCCCCEEEEEE
HGERNYPVRKIASDLDIALPDGTGDAAYLRRLATILPELSARARWDIVFYNAGVDVHAED
CCCCCCCHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEECCC
RLGRLALSNGGLRARDEMVIGHFRALGIPVCGVIGGGYSTDVPALASRHAILFEVASTYA
CCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHCCCCEEEEHHHCC
>Mature Secondary Structure 
PLQIVHHPDYDAGFATNHRFPMSKYPLLMEALRARGLASPDALNTTEPAPASWLKLAHA
CEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
ADYVDQVISCSVPEKIEREIGFPVGPRVSLRAQLATGGTILAARLALRHGIACNTAGGSH
HHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEECCCCCC
HARRAQGAGFCTFNDVAVASLVLLDEGAAQNILVVDLDVHQGDGTADILSDEPGVFTFSM
HHHHHCCCCEEEECHHHHHEEEEECCCCCCCEEEEEEEEECCCCCEEECCCCCCEEEEEE
HGERNYPVRKIASDLDIALPDGTGDAAYLRRLATILPELSARARWDIVFYNAGVDVHAED
CCCCCCCHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEECCC
RLGRLALSNGGLRARDEMVIGHFRALGIPVCGVIGGGYSTDVPALASRHAILFEVASTYA
CCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHCCCCEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]