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The map label for this gene is corA [H]

Identifier: 13474698

GI number: 13474698

Start: 4534907

End: 4535914

Strand: Direct

Name: corA [H]

Synonym: mlr5644

Alternate gene names: 13474698

Gene position: 4534907-4535914 (Clockwise)

Preceding gene: 13474697

Following gene: 13474700

Centisome position: 64.45

GC content: 61.51

Gene sequence:

>1008_bases
ATGGAATATGTCCGAGAGTTCAAGCCCGCGGCGCCGACATCAGGCATTATCGCCTCCAGTGTCTACACGGCCGGGCGGCG
TATCGCCGACATTCCGATCGAGGAAGCCGGCGAATGGGCCAAGAAATCGGGACATGTCGTCTGGATCGGGCTGCTCGAAC
CGGATCGCGAGCTTCTGTTGCGCGTCCAGGCGCAGTTCCATCTGCATGAACTGGCGATCGAGGATGCCGAGCATCCGCAC
CAGCGGCCGAAGATCGAGCAATATGGCGATGCGCTGTTCATCGTCGCCCGCACCGCGCAATTGATCGAAGGACGGGTGAC
TTTCGGCGAGACGCATCTGTTCGTCGGCTCGGGCTATATCGTCAGCGTCAGGCATGGCCCGTCGACCTCCTACGCCGCCG
TGCGCCAGCACTGGGAAAGCTGTCCGCATTCGCTGGCCAAGGGCGAGGATTTCGTCCTCTACGCCATTCTCGATTTCATC
GTCGACAACTACATGCCAGTGCTCGAGCAGATCGAGGACGAGGTCGAGGTGATCGAGGACAGGGTGCTTTTGAAGCCGAT
GACCGGTCCTGATATCGAGCGGCTCTACATGCTGCGCCGCGATCTGCTGCGCCTGCGCAATGCGGCACTTCCGCTGGTGG
AAGTCTGCCGCCGCCTGACCAGCGCCGACCTGCCGCAGATCCATTCGGCCATGCACCCGTTGTTTCGCGATGTGACCGAC
CACATCCGCACCGTCCAGGAGAAGATCGACAGTCTGCGCGAGGTGCTGGCCTTCGCCTTCGAGGCGAGCCTGCTGGTCGG
TCAGAGCCAGGAAACGGCGATTTCCAAGAAACTCGCCTCCTGGGCGGCCATACTGGCCGTGCCGACGGCGTTCGCCGGCA
TCTACGGCATGAACTTCACCGACATGCCGGAACTGAAGATGGAATATGGCTACCCGATCGTTCTGGCCACCATCGCGACG
ATCTGCGCGTTTCTCTACTGGCGGTTCCGCAAGAATGGGTGGCTGTGA

Upstream 100 bases:

>100_bases
ATGAACGTTCATCCTCTCGAACGCTAGATCATATTGCGCTAAACTATCCCGGCGTTAAGCTTCTCAGGCCTTGATAGGGG
CCTGCTTTCAGGAGGCTGCG

Downstream 100 bases:

>100_bases
GGGTAGGCAGTAGGCAGTAGGCAGTAGGCAGTATTGTCCTACTGCTGATCCCCACTGCCTATTTCCTATCTATCGATTCC
GCCGCCGCTCCGCCGCCGGC

Product: metal-transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MEYVREFKPAAPTSGIIASSVYTAGRRIADIPIEEAGEWAKKSGHVVWIGLLEPDRELLLRVQAQFHLHELAIEDAEHPH
QRPKIEQYGDALFIVARTAQLIEGRVTFGETHLFVGSGYIVSVRHGPSTSYAAVRQHWESCPHSLAKGEDFVLYAILDFI
VDNYMPVLEQIEDEVEVIEDRVLLKPMTGPDIERLYMLRRDLLRLRNAALPLVEVCRRLTSADLPQIHSAMHPLFRDVTD
HIRTVQEKIDSLREVLAFAFEASLLVGQSQETAISKKLASWAAILAVPTAFAGIYGMNFTDMPELKMEYGYPIVLATIAT
ICAFLYWRFRKNGWL

Sequences:

>Translated_335_residues
MEYVREFKPAAPTSGIIASSVYTAGRRIADIPIEEAGEWAKKSGHVVWIGLLEPDRELLLRVQAQFHLHELAIEDAEHPH
QRPKIEQYGDALFIVARTAQLIEGRVTFGETHLFVGSGYIVSVRHGPSTSYAAVRQHWESCPHSLAKGEDFVLYAILDFI
VDNYMPVLEQIEDEVEVIEDRVLLKPMTGPDIERLYMLRRDLLRLRNAALPLVEVCRRLTSADLPQIHSAMHPLFRDVTD
HIRTVQEKIDSLREVLAFAFEASLLVGQSQETAISKKLASWAAILAVPTAFAGIYGMNFTDMPELKMEYGYPIVLATIAT
ICAFLYWRFRKNGWL
>Mature_335_residues
MEYVREFKPAAPTSGIIASSVYTAGRRIADIPIEEAGEWAKKSGHVVWIGLLEPDRELLLRVQAQFHLHELAIEDAEHPH
QRPKIEQYGDALFIVARTAQLIEGRVTFGETHLFVGSGYIVSVRHGPSTSYAAVRQHWESCPHSLAKGEDFVLYAILDFI
VDNYMPVLEQIEDEVEVIEDRVLLKPMTGPDIERLYMLRRDLLRLRNAALPLVEVCRRLTSADLPQIHSAMHPLFRDVTD
HIRTVQEKIDSLREVLAFAFEASLLVGQSQETAISKKLASWAAILAVPTAFAGIYGMNFTDMPELKMEYGYPIVLATIAT
ICAFLYWRFRKNGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=336, Percent_Identity=24.1071428571429, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 37956; Mature: 37956

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYVREFKPAAPTSGIIASSVYTAGRRIADIPIEEAGEWAKKSGHVVWIGLLEPDRELLL
CCCHHHCCCCCCCCCHHHHHHHHHCCEEECCCHHHHHHHHHHCCCEEEEEECCCCHHHHH
RVQAQFHLHELAIEDAEHPHQRPKIEQYGDALFIVARTAQLIEGRVTFGETHLFVGSGYI
HHHHHHHHHHHHHHCCCCCCCCCCHHHHCCEEEEHHHHHHHHHCCEEECCEEEEEECCEE
VSVRHGPSTSYAAVRQHWESCPHSLAKGEDFVLYAILDFIVDNYMPVLEQIEDEVEVIED
EEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVLLKPMTGPDIERLYMLRRDLLRLRNAALPLVEVCRRLTSADLPQIHSAMHPLFRDVTD
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
HIRTVQEKIDSLREVLAFAFEASLLVGQSQETAISKKLASWAAILAVPTAFAGIYGMNFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DMPELKMEYGYPIVLATIATICAFLYWRFRKNGWL
CCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEYVREFKPAAPTSGIIASSVYTAGRRIADIPIEEAGEWAKKSGHVVWIGLLEPDRELLL
CCCHHHCCCCCCCCCHHHHHHHHHCCEEECCCHHHHHHHHHHCCCEEEEEECCCCHHHHH
RVQAQFHLHELAIEDAEHPHQRPKIEQYGDALFIVARTAQLIEGRVTFGETHLFVGSGYI
HHHHHHHHHHHHHHCCCCCCCCCCHHHHCCEEEEHHHHHHHHHCCEEECCEEEEEECCEE
VSVRHGPSTSYAAVRQHWESCPHSLAKGEDFVLYAILDFIVDNYMPVLEQIEDEVEVIED
EEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVLLKPMTGPDIERLYMLRRDLLRLRNAALPLVEVCRRLTSADLPQIHSAMHPLFRDVTD
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
HIRTVQEKIDSLREVLAFAFEASLLVGQSQETAISKKLASWAAILAVPTAFAGIYGMNFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DMPELKMEYGYPIVLATIATICAFLYWRFRKNGWL
CCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]