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The map label for this gene is intZ [H]

Identifier: 13474553

GI number: 13474553

Start: 4374552

End: 4375733

Strand: Direct

Name: intZ [H]

Synonym: mlr5460

Alternate gene names: 13474553

Gene position: 4374552-4375733 (Clockwise)

Preceding gene: 13474545

Following gene: 13474554

Centisome position: 62.17

GC content: 61.51

Gene sequence:

>1182_bases
ATGACAAGAGCAAAGGACAGGCTGTCGGCGGTGCAGGTTAAGCAATCGCCTGCCGGCAAGTATGCGGATGGCGGCGGGCT
GTGGTTGGTGAAGTCCAGCAAGGATACTGGCAAGTGGGTTCTGCGCGCGGTGGTGCATGGCCGTCGCCGCGAGATGGGTC
TTGGCTCGGTTTCCGATGTCGGACTGGCCGAAGCCCGCAAGTCGGCGGACAAGTGGCGCACGGTCGTTCGGGCTGGCGGC
GATCCTATTAAAGAGCGGGCTCGGCAGAAGCGCGAGGCGGCGCGGAACCTCCATCTTTTGAAGCATGTCGCGGAAGACTG
TTTCGATGCGATCAAGGGCAACCTCAGGGGACAAGGAAAGGCGGGTCGATGGTTCTCGCCGCTCGAACTCCATGTGTTAC
CCAAGCTCGGAAAGGTGCCGGTGGCCGATCTCGACCAAGTGGACATCCGCGACACTCTGAAACCGCTTCGGGATACGAAA
TTCGAGACGATGCGAAAGGCGCTCAATCGCCTTGACATGGTTGTGCGCCACGCCGCCGCGCTTGGCCTCGACGTTGACAC
GCAAGTTGTGGACAAGGCGAAGGCGCTGATTGGAGCGTCACAGCACAAAGCCGTGAACATCCCGGCGATGCCTTGGCATG
AGGTGCCTGGGTTTTATCAAAGCCTGAGCGTGGGATCAGTAACGCATCTAGCCTTGCGGCTGCTGATACTCACGGGAGTC
CGCTCGCGGCCTCTGCGGTTCCTGCGCGTCGATCACATTGCCGGTGACGTGTGGACCATACCTGCCGACATGATGAAGGG
TCGCGAGGGTGCGACTGGCGATTTCAGGGTCCCGCTATCAAAGGAAGCCCTGGCCGTGATCGAGCAGGCCAAGCGTCATG
CTCGTGATGGTTTCCTGTTCCCGTCTCTCAGGCGCGGTGTCGTGAGCGACATGACGCTAAGCCGCTACATGGAACGGCGG
AAGCTGACAGCGCGCCCGCATGGCTTCCGGTCATCGCTGCGGGATTGGCTTGCCGAATGCACTGATGCGCCTCACGAGGT
AGCGGAGACGGTCTTGGGCCACAAAGTCGGCGGTGCGGTCGAGCGCGCGTATCGACGGACCGACTTCATCGACCAGCGGG
CCAAGCTTATGGAGCGGTGGGCAGACCATTGCAAGGTGGTGCAACTGGTGAGCGCGGTCTGA

Upstream 100 bases:

>100_bases
CTGATTTTGTTGCGAAAATTGCAACGCGTGAGCGCCAGGCATTGTCACTCGGGGTCATTCCATCTACACGTAGAGGGTGG
ACCAAAGGGTGGACTTAGAA

Downstream 100 bases:

>100_bases
CTGTCTCGTATCTGGTGTTTTAGGAACTAACCATCTCGCCTTAGGTCAATCCGGGTCACTTGTGAAGCAATGAGGGCCCG
ACCATGAATTTCGACCACCA

Product: CP4-like integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTRAKDRLSAVQVKQSPAGKYADGGGLWLVKSSKDTGKWVLRAVVHGRRREMGLGSVSDVGLAEARKSADKWRTVVRAGG
DPIKERARQKREAARNLHLLKHVAEDCFDAIKGNLRGQGKAGRWFSPLELHVLPKLGKVPVADLDQVDIRDTLKPLRDTK
FETMRKALNRLDMVVRHAAALGLDVDTQVVDKAKALIGASQHKAVNIPAMPWHEVPGFYQSLSVGSVTHLALRLLILTGV
RSRPLRFLRVDHIAGDVWTIPADMMKGREGATGDFRVPLSKEALAVIEQAKRHARDGFLFPSLRRGVVSDMTLSRYMERR
KLTARPHGFRSSLRDWLAECTDAPHEVAETVLGHKVGGAVERAYRRTDFIDQRAKLMERWADHCKVVQLVSAV

Sequences:

>Translated_393_residues
MTRAKDRLSAVQVKQSPAGKYADGGGLWLVKSSKDTGKWVLRAVVHGRRREMGLGSVSDVGLAEARKSADKWRTVVRAGG
DPIKERARQKREAARNLHLLKHVAEDCFDAIKGNLRGQGKAGRWFSPLELHVLPKLGKVPVADLDQVDIRDTLKPLRDTK
FETMRKALNRLDMVVRHAAALGLDVDTQVVDKAKALIGASQHKAVNIPAMPWHEVPGFYQSLSVGSVTHLALRLLILTGV
RSRPLRFLRVDHIAGDVWTIPADMMKGREGATGDFRVPLSKEALAVIEQAKRHARDGFLFPSLRRGVVSDMTLSRYMERR
KLTARPHGFRSSLRDWLAECTDAPHEVAETVLGHKVGGAVERAYRRTDFIDQRAKLMERWADHCKVVQLVSAV
>Mature_392_residues
TRAKDRLSAVQVKQSPAGKYADGGGLWLVKSSKDTGKWVLRAVVHGRRREMGLGSVSDVGLAEARKSADKWRTVVRAGGD
PIKERARQKREAARNLHLLKHVAEDCFDAIKGNLRGQGKAGRWFSPLELHVLPKLGKVPVADLDQVDIRDTLKPLRDTKF
ETMRKALNRLDMVVRHAAALGLDVDTQVVDKAKALIGASQHKAVNIPAMPWHEVPGFYQSLSVGSVTHLALRLLILTGVR
SRPLRFLRVDHIAGDVWTIPADMMKGREGATGDFRVPLSKEALAVIEQAKRHARDGFLFPSLRRGVVSDMTLSRYMERRK
LTARPHGFRSSLRDWLAECTDAPHEVAETVLGHKVGGAVERAYRRTDFIDQRAKLMERWADHCKVVQLVSAV

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=371, Percent_Identity=29.6495956873315, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788974, Length=382, Percent_Identity=27.7486910994764, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788690, Length=392, Percent_Identity=23.7244897959184, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 43813; Mature: 43682

Theoretical pI: Translated: 10.95; Mature: 10.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRAKDRLSAVQVKQSPAGKYADGGGLWLVKSSKDTGKWVLRAVVHGRRREMGLGSVSDV
CCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]