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The map label for this gene is ubiE [C]

Identifier: 13474485

GI number: 13474485

Start: 4297147

End: 4297992

Strand: Direct

Name: ubiE [C]

Synonym: mlr5379

Alternate gene names: 13474485

Gene position: 4297147-4297992 (Clockwise)

Preceding gene: 13474483

Following gene: 13474487

Centisome position: 61.07

GC content: 64.07

Gene sequence:

>846_bases
ATGCCGCAATCCGCGCCGCCGAACACACGGCAAGCAGTGCTCTGGAACGATGTCAGCGGAAAGGCCTGGGTCGAGATGCA
GCCGATCCTCGACGAGATACTGGCGCCGTTCGAGCGGCTGGTGGTCGATGCCGGCTATCCCAGGGAAGGGGGCAATGTCC
TGGACATCGGCTGTGGCGCCGGCGCCACAACCCTGGCGATGGCGCGCCGCGTGGGCAACGACGGAAATTGTGTGGGGCTC
GACATCTCGCAACCGCTTGTCGCCCTGGCGACGGAGCGCACGAAGCTGGGAGAGGTAGCAAACGCAAGTTTTGAAGTGGG
CGATGCCCAGACATATGCGTTCGAATCCGGGCATTTCGACGCTGCAATCTCCCGCTTCGGTGTCATGTTCTTCGATGATC
CCATGGCCGCGTTCACCAACATAAGAAAGGCCGTGAGGCGCCGTGGCAAACTCGCCTTTGTTGCCTGGCGCAGTCCGCTT
GAGAATGATTTCATGACGACCGCCGTGCGAGCGGCTGCGCCTTTCCTGCCGCCTGCACCCGCGCCAGACCCCGATGCGCC
GGGTCAGTTTGCCTTTGCCGACGGCGCCAAGGTGAGGCGGATCCTGGAAGCGAGCGGCTGGGCTTCAATCGAAGTCGAAC
AGGCGGACGTCCCGTGTCGGATCGCCCAACGCGATCTGATGGCGTATGCCACCCGGCTAGGGCCGCTCGGCGCCGCGCTG
CGCGAGGTTGACCGGGCAACGGCCGAAAGAATCACCACGGTGTTGCCGGCTGCGTTCGCGCCTTTCGTTGACGACGGTGA
GGCTCGCTTCAATGCCGCCTGCTGGCTGGTGACGGCACTTGCTTGA

Upstream 100 bases:

>100_bases
ACTTCGGCAATGTCCATATTTCATGCTTGACCTCAAGTCGGCTTGAACTCGTAGAGTGCTCGCGACGATCAGTTAGAGCA
ACATGAAAGCGAGGTCCGTT

Downstream 100 bases:

>100_bases
AACGGTGGCTATCTATCGGAAAAACCGATATCGACTTTCTGACAAATGAATTTGCGAAACCGGAATTTTCCAAGCACCTT
CGGTTTCAGGGACCAAAGCC

Product: aklanonic acid methyl transferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase; UbiE/COQ5 Methyltransferase; S-Adenosyl-L-Methionine-Dependent Methyltransferase; Methyltransferase Protein; Methyltransferase UbiE/COQ5 Family; Ubiquinone/Menaquinone Biosynthesis Methyltransferase UbiE; SAM-Dependent Methyltransferase; Methlytransferase UbiE/COQ5 Family Protein; UbiE/COQ5 Family Methlytransferase; UbiE/COQ5 Family Methyltransferase; Aklanonic Acid Methyl Transferase; MCP Methyltransferase CheR-Type; Methyltransferase Domain-Containing Protein; Demethylmenaquinone Methyltransferase; Methyltransferase Domain Family; Menaquinone Biosynthesis Methyltransferase

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MPQSAPPNTRQAVLWNDVSGKAWVEMQPILDEILAPFERLVVDAGYPREGGNVLDIGCGAGATTLAMARRVGNDGNCVGL
DISQPLVALATERTKLGEVANASFEVGDAQTYAFESGHFDAAISRFGVMFFDDPMAAFTNIRKAVRRRGKLAFVAWRSPL
ENDFMTTAVRAAAPFLPPAPAPDPDAPGQFAFADGAKVRRILEASGWASIEVEQADVPCRIAQRDLMAYATRLGPLGAAL
REVDRATAERITTVLPAAFAPFVDDGEARFNAACWLVTALA

Sequences:

>Translated_281_residues
MPQSAPPNTRQAVLWNDVSGKAWVEMQPILDEILAPFERLVVDAGYPREGGNVLDIGCGAGATTLAMARRVGNDGNCVGL
DISQPLVALATERTKLGEVANASFEVGDAQTYAFESGHFDAAISRFGVMFFDDPMAAFTNIRKAVRRRGKLAFVAWRSPL
ENDFMTTAVRAAAPFLPPAPAPDPDAPGQFAFADGAKVRRILEASGWASIEVEQADVPCRIAQRDLMAYATRLGPLGAAL
REVDRATAERITTVLPAAFAPFVDDGEARFNAACWLVTALA
>Mature_280_residues
PQSAPPNTRQAVLWNDVSGKAWVEMQPILDEILAPFERLVVDAGYPREGGNVLDIGCGAGATTLAMARRVGNDGNCVGLD
ISQPLVALATERTKLGEVANASFEVGDAQTYAFESGHFDAAISRFGVMFFDDPMAAFTNIRKAVRRRGKLAFVAWRSPLE
NDFMTTAVRAAAPFLPPAPAPDPDAPGQFAFADGAKVRRILEASGWASIEVEQADVPCRIAQRDLMAYATRLGPLGAALR
EVDRATAERITTVLPAAFAPFVDDGEARFNAACWLVTALA

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30096; Mature: 29965

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQSAPPNTRQAVLWNDVSGKAWVEMQPILDEILAPFERLVVDAGYPREGGNVLDIGCGA
CCCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCC
GATTLAMARRVGNDGNCVGLDISQPLVALATERTKLGEVANASFEVGDAQTYAFESGHFD
CHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCHH
AAISRFGVMFFDDPMAAFTNIRKAVRRRGKLAFVAWRSPLENDFMTTAVRAAAPFLPPAP
HHHHHCCEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCC
APDPDAPGQFAFADGAKVRRILEASGWASIEVEQADVPCRIAQRDLMAYATRLGPLGAAL
CCCCCCCCCEEECCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHH
REVDRATAERITTVLPAAFAPFVDDGEARFNAACWLVTALA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHEEEECC
>Mature Secondary Structure 
PQSAPPNTRQAVLWNDVSGKAWVEMQPILDEILAPFERLVVDAGYPREGGNVLDIGCGA
CCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCC
GATTLAMARRVGNDGNCVGLDISQPLVALATERTKLGEVANASFEVGDAQTYAFESGHFD
CHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCHH
AAISRFGVMFFDDPMAAFTNIRKAVRRRGKLAFVAWRSPLENDFMTTAVRAAAPFLPPAP
HHHHHCCEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCC
APDPDAPGQFAFADGAKVRRILEASGWASIEVEQADVPCRIAQRDLMAYATRLGPLGAAL
CCCCCCCCCEEECCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHH
REVDRATAERITTVLPAAFAPFVDDGEARFNAACWLVTALA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA