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The map label for this gene is glpR [H]

Identifier: 13474478

GI number: 13474478

Start: 4291205

End: 4291981

Strand: Direct

Name: glpR [H]

Synonym: mlr5371

Alternate gene names: 13474478

Gene position: 4291205-4291981 (Clockwise)

Preceding gene: 13474475

Following gene: 13474481

Centisome position: 60.99

GC content: 65.89

Gene sequence:

>777_bases
ATGGTCCATTCCAAACGCCACGGCGAGATCCTGCGGCTGCTGCAGGAAGAAGGAACCGTCACCATCGCCAGCCTGGCCGA
TCGGCTGGGTGTTTCGCTGGAAACCGTGCGCCGCGACGTCAAGCCACTCAGCAGCGACGGCTCGGTCCTGAAGATGCATG
GCGCCATCGGCCTGCCGTCCATGGTCGGCGAGGCGCCGTTCGAAAGGCGCATGCGCGAGAATGCCGATGCCAAGCGCATC
ATTGCCCGCATGGTCGCCGCCACCATCCGCGACGGGGAATCGGTCATGCTGGACACCGGCACCACGACCTCGTTCCTGGC
CCGGGAACTGCTCGGCCACCGGCGGCTGACGGTCGTTACCAATTCGTCCGATATCGCCCGCACGCTGGCCACCATCAACG
GCAACAAGGTCTATATGGCCGGCGGCGAATTGCGCAGCGATTCAGGTGCCGCGTTCGGCACTTCGGCCATCGAGTTCGTC
AGCCGCTTCTCGGTCAGCCATGCCATCATATCCACTGGCGCCGTCGATGCGGTGACGGGGGTCATGGACTATGATCTGGA
AGAGGCCGAATTCGCCCGCATGGTGCTGTCGCGTGGCCAGCGCTCGCTCGTCATCACCGACCACACCAAGTTCGGCCGCC
AGGGCCTGGTCCAGGTCTGCGGCTTCGACGGCTTTTCCGAACTCGCCACCGACCGTTCGCCGCCGCACGACATAGCCGCG
GCGCTGGCGCAGGCCGGCGCGCGGCTCAGCATCGCCGGCGGCGAAGCCGGATTTTAG

Upstream 100 bases:

>100_bases
GACTTTTTTTGGGTGTTTTGCCCGAAAGCACGGGACGATATCTTTAAAAGTGCTTGAATTACCTTAAAACCGGTCAAAAG
GCGAAGTCCGGGAAACCCTA

Downstream 100 bases:

>100_bases
CCGAACATCAGCGATTGGTTGACCCACACCCGCCTGAAGCGCGAAGTGCCTGGACGGGTTCAGGCGACGCGCTTCAGGCC
GGCAAGGCGCGAAAACTCAT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MVHSKRHGEILRLLQEEGTVTIASLADRLGVSLETVRRDVKPLSSDGSVLKMHGAIGLPSMVGEAPFERRMRENADAKRI
IARMVAATIRDGESVMLDTGTTTSFLARELLGHRRLTVVTNSSDIARTLATINGNKVYMAGGELRSDSGAAFGTSAIEFV
SRFSVSHAIISTGAVDAVTGVMDYDLEEAEFARMVLSRGQRSLVITDHTKFGRQGLVQVCGFDGFSELATDRSPPHDIAA
ALAQAGARLSIAGGEAGF

Sequences:

>Translated_258_residues
MVHSKRHGEILRLLQEEGTVTIASLADRLGVSLETVRRDVKPLSSDGSVLKMHGAIGLPSMVGEAPFERRMRENADAKRI
IARMVAATIRDGESVMLDTGTTTSFLARELLGHRRLTVVTNSSDIARTLATINGNKVYMAGGELRSDSGAAFGTSAIEFV
SRFSVSHAIISTGAVDAVTGVMDYDLEEAEFARMVLSRGQRSLVITDHTKFGRQGLVQVCGFDGFSELATDRSPPHDIAA
ALAQAGARLSIAGGEAGF
>Mature_258_residues
MVHSKRHGEILRLLQEEGTVTIASLADRLGVSLETVRRDVKPLSSDGSVLKMHGAIGLPSMVGEAPFERRMRENADAKRI
IARMVAATIRDGESVMLDTGTTTSFLARELLGHRRLTVVTNSSDIARTLATINGNKVYMAGGELRSDSGAAFGTSAIEFV
SRFSVSHAIISTGAVDAVTGVMDYDLEEAEFARMVLSRGQRSLVITDHTKFGRQGLVQVCGFDGFSELATDRSPPHDIAA
ALAQAGARLSIAGGEAGF

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=30.1587301587302, Blast_Score=153, Evalue=9e-39,
Organism=Escherichia coli, GI87082344, Length=232, Percent_Identity=34.4827586206897, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1789519, Length=255, Percent_Identity=27.843137254902, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1789059, Length=250, Percent_Identity=26.4, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=28.82096069869, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI226510968, Length=256, Percent_Identity=27.734375, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788069, Length=236, Percent_Identity=27.5423728813559, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=27.3913043478261, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790753, Length=247, Percent_Identity=25.5060728744939, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790635, Length=251, Percent_Identity=24.7011952191235, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787063, Length=234, Percent_Identity=24.3589743589744, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27504; Mature: 27504

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2 ; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHSKRHGEILRLLQEEGTVTIASLADRLGVSLETVRRDVKPLSSDGSVLKMHGAIGLPS
CCCCCHHHHHHHHHHHCCCEEHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCCCCCHH
MVGEAPFERRMRENADAKRIIARMVAATIRDGESVMLDTGTTTSFLARELLGHRRLTVVT
HHCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCEEEEEE
NSSDIARTLATINGNKVYMAGGELRSDSGAAFGTSAIEFVSRFSVSHAIISTGAVDAVTG
CCHHHHHHHHHCCCCEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VMDYDLEEAEFARMVLSRGQRSLVITDHTKFGRQGLVQVCGFDGFSELATDRSPPHDIAA
HHHCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHH
ALAQAGARLSIAGGEAGF
HHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MVHSKRHGEILRLLQEEGTVTIASLADRLGVSLETVRRDVKPLSSDGSVLKMHGAIGLPS
CCCCCHHHHHHHHHHHCCCEEHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCCCCCHH
MVGEAPFERRMRENADAKRIIARMVAATIRDGESVMLDTGTTTSFLARELLGHRRLTVVT
HHCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCEEEEEE
NSSDIARTLATINGNKVYMAGGELRSDSGAAFGTSAIEFVSRFSVSHAIISTGAVDAVTG
CCHHHHHHHHHCCCCEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VMDYDLEEAEFARMVLSRGQRSLVITDHTKFGRQGLVQVCGFDGFSELATDRSPPHDIAA
HHHCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHH
ALAQAGARLSIAGGEAGF
HHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]