BacMap

Definition	Mesorhizobium loti MAFF303099 chromosome, complete genome.
Accession	NC_002678
Length	7,036,071

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The map label for this gene is yeaE [H]

Identifier: 13474445

GI number: 13474445

Start: 4255127

End: 4255972

Strand: Direct

Name: yeaE [H]

Synonym: mlr5327

Alternate gene names: 13474445

Gene position: 4255127-4255972 (Clockwise)

Preceding gene: 13474444

Following gene: 13474447

Centisome position: 60.48

GC content: 64.66

Gene sequence:

>846_bases
ATGCCATCCACCGTCAGAACCACCACGCTGCCCTCTGGCGAAACCGTCCAGGTGCTCGGCCAGGGCACCTGGAAGATGGG
TGAGGATTCGCGTCGCCGTGCCGATGAGGTGAACGCTCTCAAACTCGGCCTCGACCTTGGCCTCACACTGATCGACACCG
CCGAAATGTATGCCAGCGGCGGCGCCGAAGAGGTCGTGGCTGAAGCCATTGCCGGGCGCCGCGCCGAGGTCTTCGTGGTC
TCGAAAGTTCTGCCATCGAACGCGTCGCACGCGGGCGTGCAGCGCGCCTGCGAGAACAGCCTCAAGCGCCTGCGCACCGA
CCGCATCGATCTCTACCTCCTGCATTGGCCGGGCAGCGTGCCTTTGGCCGAGACGGTCGAGGCCTTCGAGGCCGTGAAGA
AGGCCGGCAAGATCCGCCATTGGGGCGTCAGCAATTTCGACACCGAGGACATGGACGATCTGGCCGGCTTGCCCGACGGC
AGCAACGTCCAGACCAACCAGGTGCTTTACAATCTCGTCCGGCGCGGCCCCGAGTTCGATCTGGCGCCCTGGAGCCGCAA
GCGAGGCATTCCACTGATGGCCTATTCGCCGGTCGAGCAGGGCGCGCTGGCGCGCAATACTGGGCTTGATGCCGTCGCCG
CCCGCCACAATGCGACTGCCGCGCAAATCGCGCTGGCTTGGGTGATGCATCAGGACGGCATCATCGCCATTCCAAAGGCC
AGCAGCCAGGAACATGTCCGCCAGAATTTTGCGGCGCTCGACATCAAGCTTACGCCGCAGGACATCACCGACCTCGACCG
TGCGTTCCCGCCACCGACCCGCAAGCGTGGCCTGGAGATGATCTGA

Upstream 100 bases:

>100_bases
CGGTGAAGTGAGACTTTCGCGACGGGGAGATTTGGGCGAGAAACGCCTTTGGATTTCTCGCCTGCCCTGTGATGCGATTC
GGCCTCGAACGGAGCCTGCC

Downstream 100 bases:

>100_bases
CTACTTCCCCGCCAGTCCCTTCAGCCGGTAGAGCGCCTCCAGCGCTTCCCGTGGCGTCATCTCGTCGGGATTGATGTCGC
CGAGGGCGGCGCCGAGCGCG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MPSTVRTTTLPSGETVQVLGQGTWKMGEDSRRRADEVNALKLGLDLGLTLIDTAEMYASGGAEEVVAEAIAGRRAEVFVV
SKVLPSNASHAGVQRACENSLKRLRTDRIDLYLLHWPGSVPLAETVEAFEAVKKAGKIRHWGVSNFDTEDMDDLAGLPDG
SNVQTNQVLYNLVRRGPEFDLAPWSRKRGIPLMAYSPVEQGALARNTGLDAVAARHNATAAQIALAWVMHQDGIIAIPKA
SSQEHVRQNFAALDIKLTPQDITDLDRAFPPPTRKRGLEMI

Sequences:

>Translated_281_residues
MPSTVRTTTLPSGETVQVLGQGTWKMGEDSRRRADEVNALKLGLDLGLTLIDTAEMYASGGAEEVVAEAIAGRRAEVFVV
SKVLPSNASHAGVQRACENSLKRLRTDRIDLYLLHWPGSVPLAETVEAFEAVKKAGKIRHWGVSNFDTEDMDDLAGLPDG
SNVQTNQVLYNLVRRGPEFDLAPWSRKRGIPLMAYSPVEQGALARNTGLDAVAARHNATAAQIALAWVMHQDGIIAIPKA
SSQEHVRQNFAALDIKLTPQDITDLDRAFPPPTRKRGLEMI
>Mature_280_residues
PSTVRTTTLPSGETVQVLGQGTWKMGEDSRRRADEVNALKLGLDLGLTLIDTAEMYASGGAEEVVAEAIAGRRAEVFVVS
KVLPSNASHAGVQRACENSLKRLRTDRIDLYLLHWPGSVPLAETVEAFEAVKKAGKIRHWGVSNFDTEDMDDLAGLPDGS
NVQTNQVLYNLVRRGPEFDLAPWSRKRGIPLMAYSPVEQGALARNTGLDAVAARHNATAAQIALAWVMHQDGIIAIPKAS
SQEHVRQNFAALDIKLTPQDITDLDRAFPPPTRKRGLEMI

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI310109922, Length=287, Percent_Identity=29.9651567944251, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI24497583, Length=307, Percent_Identity=29.6416938110749, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI5453543, Length=307, Percent_Identity=28.9902280130293, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI45446745, Length=307, Percent_Identity=28.9902280130293, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI4503285, Length=307, Percent_Identity=28.9902280130293, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI310109920, Length=307, Percent_Identity=28.9902280130293, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI24497585, Length=307, Percent_Identity=28.9902280130293, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI5174695, Length=295, Percent_Identity=26.7796610169492, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI223468663, Length=295, Percent_Identity=27.1186440677966, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI24497577, Length=302, Percent_Identity=26.8211920529801, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI5174391, Length=302, Percent_Identity=26.8211920529801, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI300116273, Length=279, Percent_Identity=26.8817204301075, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4502049, Length=294, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI291291012, Length=263, Percent_Identity=26.9961977186312, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI27436969, Length=320, Percent_Identity=24.375, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4504825, Length=310, Percent_Identity=24.8387096774194, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI27436966, Length=325, Percent_Identity=24.6153846153846, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI41152114, Length=170, Percent_Identity=28.8235294117647, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI41327764, Length=195, Percent_Identity=29.2307692307692, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788081, Length=268, Percent_Identity=52.2388059701493, Blast_Score=289, Evalue=1e-79,
Organism=Escherichia coli, GI87081735, Length=294, Percent_Identity=29.9319727891156, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786400, Length=252, Percent_Identity=29.7619047619048, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788070, Length=307, Percent_Identity=28.9902280130293, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI87082198, Length=275, Percent_Identity=29.0909090909091, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787674, Length=276, Percent_Identity=24.6376811594203, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI48994888, Length=283, Percent_Identity=28.9752650176678, Blast_Score=68, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17561298, Length=293, Percent_Identity=30.3754266211604, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17564128, Length=304, Percent_Identity=29.2763157894737, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17552492, Length=271, Percent_Identity=29.1512915129151, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17537077, Length=297, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71998625, Length=242, Percent_Identity=26.8595041322314, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17550248, Length=304, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17537075, Length=297, Percent_Identity=26.5993265993266, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17561300, Length=265, Percent_Identity=27.1698113207547, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17566692, Length=303, Percent_Identity=27.0627062706271, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17538386, Length=281, Percent_Identity=24.5551601423488, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324694, Length=292, Percent_Identity=27.0547945205479, Blast_Score=92, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320576, Length=302, Percent_Identity=28.476821192053, Blast_Score=92, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6322556, Length=248, Percent_Identity=25.4032258064516, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320079, Length=276, Percent_Identity=25.7246376811594, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129731, Length=299, Percent_Identity=28.0936454849498, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24644950, Length=305, Percent_Identity=27.8688524590164, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24657054, Length=291, Percent_Identity=26.4604810996564, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI45553081, Length=295, Percent_Identity=27.7966101694915, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24663317, Length=297, Percent_Identity=25.5892255892256, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24662789, Length=299, Percent_Identity=27.0903010033445, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21356425, Length=304, Percent_Identity=23.3552631578947, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281366140, Length=256, Percent_Identity=27.34375, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24662781, Length=286, Percent_Identity=25.1748251748252, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 30640; Mature: 30509

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSTVRTTTLPSGETVQVLGQGTWKMGEDSRRRADEVNALKLGLDLGLTLIDTAEMYASG
CCCCCEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHEEEHHHHCCHHHHHHHHHHCC
GAEEVVAEAIAGRRAEVFVVSKVLPSNASHAGVQRACENSLKRLRTDRIDLYLLHWPGSV
CHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
PLAETVEAFEAVKKAGKIRHWGVSNFDTEDMDDLAGLPDGSNVQTNQVLYNLVRRGPEFD
CHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCC
LAPWSRKRGIPLMAYSPVEQGALARNTGLDAVAARHNATAAQIALAWVMHQDGIIAIPKA
CCCCHHCCCCEEEEECCHHCCCHHHCCCCHHHHHHCCCHHHHHHHHHHCCCCCEEEECCC
SSQEHVRQNFAALDIKLTPQDITDLDRAFPPPTRKRGLEMI
CCHHHHHHCCEEEEEEECCHHHHHHHHCCCCCHHHCCCCCC
>Mature Secondary Structure 
PSTVRTTTLPSGETVQVLGQGTWKMGEDSRRRADEVNALKLGLDLGLTLIDTAEMYASG
CCCCEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHEEEHHHHCCHHHHHHHHHHCC
GAEEVVAEAIAGRRAEVFVVSKVLPSNASHAGVQRACENSLKRLRTDRIDLYLLHWPGSV
CHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
PLAETVEAFEAVKKAGKIRHWGVSNFDTEDMDDLAGLPDGSNVQTNQVLYNLVRRGPEFD
CHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCC
LAPWSRKRGIPLMAYSPVEQGALARNTGLDAVAARHNATAAQIALAWVMHQDGIIAIPKA
CCCCHHCCCCEEEEECCHHCCCHHHCCCCHHHHHHCCCHHHHHHHHHHCCCCCEEEECCC
SSQEHVRQNFAALDIKLTPQDITDLDRAFPPPTRKRGLEMI
CCHHHHHHCCEEEEEEECCHHHHHHHHCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]