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The map label for this gene is exoN [H]

Identifier: 13474400

GI number: 13474400

Start: 4205937

End: 4206833

Strand: Direct

Name: exoN [H]

Synonym: mlr5275

Alternate gene names: 13474400

Gene position: 4205937-4206833 (Clockwise)

Preceding gene: 13474399

Following gene: 13474401

Centisome position: 59.78

GC content: 62.65

Gene sequence:

>897_bases
ATGAAGAAAATCAGGAAGGCCGTGATACCGGTGGCGGGGCTTGGAACACGGTTCCTGCCGGCGACCAAGTCGATGCCGAA
GGAAATGCTCCCGGTGGTCGACAGGCCCGTCGTGCAATATGCGGTGGACGAGGCCTTCGAAGCCGGCATCGAGCACATCG
TGTTCGTGACCGGCCGCAACAAGGCGGTCATCGAGGACTATTTCGACCTGCATCCGGAATTGATCGGAACCTTGGAGCAG
ACCGGCAAGAAGACCCAGCTGGAGGCGCTCGAAAGCATGCTGCCGGTGGCCGGCGCCACCTCCTTCATCCGCCAGCAATC
CCCGCAGGGCCTCGGCCACGCCGTCTGGTGCGCCCGCGAGGTCATCGGCAACGAACCCTTCGCTTTGCTTTTGCCAGACA
TGGTCTCCTTCGGCGGGCGCGGCTGTCTGGCCGAAACCGTCGACCTCTATGAGCGCACCGGCGGCAACGTCATCGCCGTC
GAGCGTTGTGATCCGAGCGAGACCAACAAATACGGCATTGTCGGCCGCGGCGCCGACATTGGCGGCGGTTTCGAGGTCAC
GGCCATGGTCGAAAAGCCGGCCCCGGCCAACGCGCCGTCAAATTTCTACATCAACGGCCGCTACATCCTGCAGCCTGAGA
TCTTCGCGCTGCTGGGCAACCAGCAGCGTGGCGCCGGCAACGAGATCCAGCTGACGGACGCCATGGTTCGCCTGTCGAAG
GACCAGCCGTTCTTTGCCCAGCCTTTCCTGGGCCGCATGTTCGACTGCGGATCCAAGGAAGGCTTCATCCAGGCCAACAT
CGCCTTCGCGCTGGCGCGCAACGACATGAAGGGCCCGGTTTTCGAGATGCTTCAGGAGTTCGTCCGGTCGCATGAACGTC
AGGAAGAAGCCGCATAA

Upstream 100 bases:

>100_bases
AGTTTGCCGTGGGGGCGGGGAGGTGAAGATGCAGGCACATGGAGGGGTTTTTCGTGGCCTGTGAATGGACTGAAGTCGAT
CTCCTCAGAAGGAATTTGCG

Downstream 100 bases:

>100_bases
TGTCCATCTTTCGGGAGTATTGCCGGATGGCTGGCGGCGAGGGGCCGACAGGCCCCCGTCGTCTGGCATGAAGCTTGCGT
TGCTTCTTGGCAATGCTCCC

Product: UTP-glucose-1-phosphate uridylyltransferase exoN

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MKKIRKAVIPVAGLGTRFLPATKSMPKEMLPVVDRPVVQYAVDEAFEAGIEHIVFVTGRNKAVIEDYFDLHPELIGTLEQ
TGKKTQLEALESMLPVAGATSFIRQQSPQGLGHAVWCAREVIGNEPFALLLPDMVSFGGRGCLAETVDLYERTGGNVIAV
ERCDPSETNKYGIVGRGADIGGGFEVTAMVEKPAPANAPSNFYINGRYILQPEIFALLGNQQRGAGNEIQLTDAMVRLSK
DQPFFAQPFLGRMFDCGSKEGFIQANIAFALARNDMKGPVFEMLQEFVRSHERQEEAA

Sequences:

>Translated_298_residues
MKKIRKAVIPVAGLGTRFLPATKSMPKEMLPVVDRPVVQYAVDEAFEAGIEHIVFVTGRNKAVIEDYFDLHPELIGTLEQ
TGKKTQLEALESMLPVAGATSFIRQQSPQGLGHAVWCAREVIGNEPFALLLPDMVSFGGRGCLAETVDLYERTGGNVIAV
ERCDPSETNKYGIVGRGADIGGGFEVTAMVEKPAPANAPSNFYINGRYILQPEIFALLGNQQRGAGNEIQLTDAMVRLSK
DQPFFAQPFLGRMFDCGSKEGFIQANIAFALARNDMKGPVFEMLQEFVRSHERQEEAA
>Mature_298_residues
MKKIRKAVIPVAGLGTRFLPATKSMPKEMLPVVDRPVVQYAVDEAFEAGIEHIVFVTGRNKAVIEDYFDLHPELIGTLEQ
TGKKTQLEALESMLPVAGATSFIRQQSPQGLGHAVWCAREVIGNEPFALLLPDMVSFGGRGCLAETVDLYERTGGNVIAV
ERCDPSETNKYGIVGRGADIGGGFEVTAMVEKPAPANAPSNFYINGRYILQPEIFALLGNQQRGAGNEIQLTDAMVRLSK
DQPFFAQPFLGRMFDCGSKEGFIQANIAFALARNDMKGPVFEMLQEFVRSHERQEEAA

Specific function: May Play A Role In Stationary Phase Survival. [C]

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=282, Percent_Identity=42.9078014184397, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1788355, Length=285, Percent_Identity=39.2982456140351, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1788351, Length=267, Percent_Identity=25.8426966292135, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790224, Length=265, Percent_Identity=25.6603773584906, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32639; Mature: 32639

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIRKAVIPVAGLGTRFLPATKSMPKEMLPVVDRPVVQYAVDEAFEAGIEHIVFVTGRN
CCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCC
KAVIEDYFDLHPELIGTLEQTGKKTQLEALESMLPVAGATSFIRQQSPQGLGHAVWCARE
CCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHH
VIGNEPFALLLPDMVSFGGRGCLAETVDLYERTGGNVIAVERCDPSETNKYGIVGRGADI
HHCCCCCEEECCHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCC
GGGFEVTAMVEKPAPANAPSNFYINGRYILQPEIFALLGNQQRGAGNEIQLTDAMVRLSK
CCCEEEEEEEECCCCCCCCCCEEECCEEEECCHHHHHCCCCCCCCCCEEEHHHHHHHHCC
DQPFFAQPFLGRMFDCGSKEGFIQANIAFALARNDMKGPVFEMLQEFVRSHERQEEAA
CCCCCCCHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKIRKAVIPVAGLGTRFLPATKSMPKEMLPVVDRPVVQYAVDEAFEAGIEHIVFVTGRN
CCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCC
KAVIEDYFDLHPELIGTLEQTGKKTQLEALESMLPVAGATSFIRQQSPQGLGHAVWCARE
CCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHH
VIGNEPFALLLPDMVSFGGRGCLAETVDLYERTGGNVIAVERCDPSETNKYGIVGRGADI
HHCCCCCEEECCHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCC
GGGFEVTAMVEKPAPANAPSNFYINGRYILQPEIFALLGNQQRGAGNEIQLTDAMVRLSK
CCCEEEEEEEECCCCCCCCCCEEECCEEEECCHHHHHCCCCCCCCCCEEEHHHHHHHHCC
DQPFFAQPFLGRMFDCGSKEGFIQANIAFALARNDMKGPVFEMLQEFVRSHERQEEAA
CCCCCCCHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8226645; 8226646; 8246891; 11481431 [H]