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The map label for this gene is rbsR [H]

Identifier: 13474146

GI number: 13474146

Start: 3936345

End: 3937370

Strand: Reverse

Name: rbsR [H]

Synonym: mll4964

Alternate gene names: 13474146

Gene position: 3937370-3936345 (Counterclockwise)

Preceding gene: 13474148

Following gene: 13474145

Centisome position: 55.96

GC content: 67.15

Gene sequence:

>1026_bases
ATGACCGATATCGCCCGGGCCGCCGGCTGCTCACAGGCGACGGTTTCCTTCGTGCTCAACAATTCGCCAGGGATCAAGCT
GTCGCAGCAGACCCGGGAGCGGGTGATCGAGGCCGCACGGGCGCTGGGCTACAGCGCGCCCGCCTTCTCGGCGCTGCGCA
AGCCGGTTGCCGCCTTCGACGGGCTGGACGGGGTGATCGGCTTTGCCGTCGACCAGCTGGCGACCAGCCCGGAAGCGGTG
GTGGCGATCGAAGGCGCGCGCCAGGCCTCGTGGAATGCCGGCAACGTTCTCCTGGTGGCGCAGACCATGGGCGACGCCGT
GATGGAGCCACGCGCCATCCAGGCGCTGACAAGACGGGGCATTTCGGCGCTGATCTACATGACCATCTTCACCCGCGAAA
TCACCGCGCCCGACTATCTCTACAGCCTCGACATCCCGGTGATCCTGCTCAATTGCTACACGGCCGACTATGCCTTCCCC
GCCGTGGTGCCGTCCGAGATCGCCGGCGGCCAGAGCTCGACAAGGCACCTGATCAGCCACGGCCACCGCCGCATCGCCAC
CATCACCGGCGAGCCGTGGATGCAGGCCGCACAGGACCGGCTGAAAGGCTATCGCCGCGCGCTCGCCACCGCCGATATCC
CCTTCGACCCGGACCTGGTGGTCGAGGGCGACTGGTCGGCCAGTGCCGGCTATGCCGCGACGGTGAAGCTGCTTGCGCTC
AAAGACCGCCCGACCGCCATCTTCTGCCAGAACGACCGCACCGCGATCGGCTGCTACGAGGCGCTGAAGGAAGCCGGCCT
GCACATTCCGCAAGACATTTCCGTGGTCGGCTACGACGACGAGGAAATCGCCCGACATTTGTTCCCGCCGCTGACCACCT
CCATCCTGCCGCACATGGCGATGGGCCAATGGGCGATCGAACAGCTCGAAGCGCCGACGGCGCCCGGACAGGGGCGCTAT
CCCATCACCAAGCTGGAGTGCCCGCTGGTGGAGCGGGAGAGTGTGAGGGGGGTGGTGGGAGGCTGA

Upstream 100 bases:

>100_bases
TGGGATTGGGGACACGACTGCCATGAGCGAGACGACGGATCCGACCATCGAGACGGCAAGGCGCCGCAAGGCGCCGGCCA
AGCCCAAGGGGCGGGTCACC

Downstream 100 bases:

>100_bases
GGCAAGGCGGCCGGGCCATGCCGTTGCGCGGTGCGGCCGGCATTCTTTCGACAGCCGACCAAGGTCATCGCATTCCGGTC
TGTCGCCGGCCAGTTTGCGG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTDIARAAGCSQATVSFVLNNSPGIKLSQQTRERVIEAARALGYSAPAFSALRKPVAAFDGLDGVIGFAVDQLATSPEAV
VAIEGARQASWNAGNVLLVAQTMGDAVMEPRAIQALTRRGISALIYMTIFTREITAPDYLYSLDIPVILLNCYTADYAFP
AVVPSEIAGGQSSTRHLISHGHRRIATITGEPWMQAAQDRLKGYRRALATADIPFDPDLVVEGDWSASAGYAATVKLLAL
KDRPTAIFCQNDRTAIGCYEALKEAGLHIPQDISVVGYDDEEIARHLFPPLTTSILPHMAMGQWAIEQLEAPTAPGQGRY
PITKLECPLVERESVRGVVGG

Sequences:

>Translated_341_residues
MTDIARAAGCSQATVSFVLNNSPGIKLSQQTRERVIEAARALGYSAPAFSALRKPVAAFDGLDGVIGFAVDQLATSPEAV
VAIEGARQASWNAGNVLLVAQTMGDAVMEPRAIQALTRRGISALIYMTIFTREITAPDYLYSLDIPVILLNCYTADYAFP
AVVPSEIAGGQSSTRHLISHGHRRIATITGEPWMQAAQDRLKGYRRALATADIPFDPDLVVEGDWSASAGYAATVKLLAL
KDRPTAIFCQNDRTAIGCYEALKEAGLHIPQDISVVGYDDEEIARHLFPPLTTSILPHMAMGQWAIEQLEAPTAPGQGRY
PITKLECPLVERESVRGVVGG
>Mature_340_residues
TDIARAAGCSQATVSFVLNNSPGIKLSQQTRERVIEAARALGYSAPAFSALRKPVAAFDGLDGVIGFAVDQLATSPEAVV
AIEGARQASWNAGNVLLVAQTMGDAVMEPRAIQALTRRGISALIYMTIFTREITAPDYLYSLDIPVILLNCYTADYAFPA
VVPSEIAGGQSSTRHLISHGHRRIATITGEPWMQAAQDRLKGYRRALATADIPFDPDLVVEGDWSASAGYAATVKLLALK
DRPTAIFCQNDRTAIGCYEALKEAGLHIPQDISVVGYDDEEIARHLFPPLTTSILPHMAMGQWAIEQLEAPTAPGQGRYP
ITKLECPLVERESVRGVVGG

Specific function: Transcriptional repressor for the ribose rbsDACBK operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=309, Percent_Identity=31.3915857605178, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1787948, Length=344, Percent_Identity=28.4883720930233, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789202, Length=305, Percent_Identity=33.1147540983607, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790369, Length=346, Percent_Identity=28.3236994219653, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1788474, Length=307, Percent_Identity=31.2703583061889, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786540, Length=335, Percent_Identity=30.1492537313433, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789068, Length=335, Percent_Identity=28.955223880597, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787580, Length=311, Percent_Identity=27.6527331189711, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787906, Length=287, Percent_Identity=26.8292682926829, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789456, Length=129, Percent_Identity=34.8837209302326, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI48994940, Length=319, Percent_Identity=24.7648902821317, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36649; Mature: 36518

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIARAAGCSQATVSFVLNNSPGIKLSQQTRERVIEAARALGYSAPAFSALRKPVAAFD
CCCHHHHCCCCCCEEEEEEECCCCCEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GLDGVIGFAVDQLATSPEAVVAIEGARQASWNAGNVLLVAQTMGDAVMEPRAIQALTRRG
CCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCCHHHHCCHHHHHHHHCC
ISALIYMTIFTREITAPDYLYSLDIPVILLNCYTADYAFPAVVPSEIAGGQSSTRHLISH
HHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEHHCCCCCCCCCCHHHCCCCCHHHHHHHC
GHRRIATITGEPWMQAAQDRLKGYRRALATADIPFDPDLVVEGDWSASAGYAATVKLLAL
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEEEEEE
KDRPTAIFCQNDRTAIGCYEALKEAGLHIPQDISVVGYDDEEIARHLFPPLTTSILPHMA
ECCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHCCHHHHHHHHHHH
MGQWAIEQLEAPTAPGQGRYPITKLECPLVERESVRGVVGG
HHHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
TDIARAAGCSQATVSFVLNNSPGIKLSQQTRERVIEAARALGYSAPAFSALRKPVAAFD
CCHHHHCCCCCCEEEEEEECCCCCEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GLDGVIGFAVDQLATSPEAVVAIEGARQASWNAGNVLLVAQTMGDAVMEPRAIQALTRRG
CCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCCHHHHCCHHHHHHHHCC
ISALIYMTIFTREITAPDYLYSLDIPVILLNCYTADYAFPAVVPSEIAGGQSSTRHLISH
HHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEHHCCCCCCCCCCHHHCCCCCHHHHHHHC
GHRRIATITGEPWMQAAQDRLKGYRRALATADIPFDPDLVVEGDWSASAGYAATVKLLAL
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEEEEEE
KDRPTAIFCQNDRTAIGCYEALKEAGLHIPQDISVVGYDDEEIARHLFPPLTTSILPHMA
ECCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHCCHHHHHHHHHHH
MGQWAIEQLEAPTAPGQGRYPITKLECPLVERESVRGVVGG
HHHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]