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The map label for this gene is murQ [H]

Identifier: 13473998

GI number: 13473998

Start: 3792125

End: 3793084

Strand: Direct

Name: murQ [H]

Synonym: mlr4770

Alternate gene names: 13473998

Gene position: 3792125-3793084 (Clockwise)

Preceding gene: 13473991

Following gene: 13473999

Centisome position: 53.9

GC content: 66.98

Gene sequence:

>960_bases
ATGGCTGAAACGCGCACCGAAGCGCTTCACAGGAATGCCGAGGGGCTGGATATCCAGGCTCCGGAAGCCATCCTTGTTTC
GCTGGCCGATGCGCAGATCGAAGCCGCCAAGGCCGTCCGCAACGCCATCCCCGCCATCGCTCGGGCAGCCGAGATCATCG
CCAGCCGGTTGAACGGCGGCGGCAAGCTCGCCTATGCCGCGGCCGGCAGTTCCGGCCTGATGGCTTTGGCCGACGCCCTG
GAGCTTCCCGGCACGTTCGGCATCCAGCGCGACCGCATCGCCATCCTGATCGCCGGCGGCGACGAGGCCTTCAAGGCGCT
GGCCGGGGGTCCTGAGGATGATACGGAGGAGGCCACGGCGGCCGTCGCCAAGGCCGGCATCGGCGCCGGCGATTGCCTGA
TCGCCCTTTCAGCCAGCGGCACCACGCCCTATGCGGTGCGCGCCATCGAGGACGCCCGGCGCCGTGGCGCTGCGACGATC
GGCATTGCCAACAACAAGGACTCGGCTCTGCTGCGCCAGGCCGAAACCGCCATCCTCTTGGAAACGCCGCCGGAAGTGAT
CGCCGGCTCGACGCGCATGGGCGCCGGCACCGCCCAGAAGATCGCGCTCAACATGTTGTCGACACTGACCGCCGTCCATC
TCGGCCATGTCCATGACGGTTATATGGTCAATCTCATGGCCGACAACATCAAGCTGCGCGACCGCGCCGCGCGCATCGTC
GCCGCCATCAGCGGGCGCGACAGGGACGAAGCCGCCCGGCTGCTCGAAAAGAGCGGCGGCGCGGTCAAGACCGCCATTCT
GCTCGCCGCCGGCGCCGACAGCGCCGATGCGGCGGAGAAACTGCTGGAAGGAACCGGCCAGAAGCTGCGACCGGCGCTTT
CCGCGATCGAGGGGAGCAAGGGGTCAAAAGCCTCTGTTCTCATCAAAACCGAACCTGAAAAAGGTCAACAGGGAGACTGA

Upstream 100 bases:

>100_bases
GCACATTTCGTCGGCTCAGCGATTTCCTGTCCGCGATTTCGTTAATGCATGTGGACAAGTGGTATTTTTTTGGTATTGTT
CTGGTATTGGAGGAACACGG

Downstream 100 bases:

>100_bases
GCATGACAACGAAATTACTGACGGCACTGCTTCTGGGCACAAGCATTCTCGGCTCGGCCGGGTTGGCTCACGCCGAGGAC
GTAACGCTCAACATCGAAAG

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MAETRTEALHRNAEGLDIQAPEAILVSLADAQIEAAKAVRNAIPAIARAAEIIASRLNGGGKLAYAAAGSSGLMALADAL
ELPGTFGIQRDRIAILIAGGDEAFKALAGGPEDDTEEATAAVAKAGIGAGDCLIALSASGTTPYAVRAIEDARRRGAATI
GIANNKDSALLRQAETAILLETPPEVIAGSTRMGAGTAQKIALNMLSTLTAVHLGHVHDGYMVNLMADNIKLRDRAARIV
AAISGRDRDEAARLLEKSGGAVKTAILLAAGADSADAAEKLLEGTGQKLRPALSAIEGSKGSKASVLIKTEPEKGQQGD

Sequences:

>Translated_319_residues
MAETRTEALHRNAEGLDIQAPEAILVSLADAQIEAAKAVRNAIPAIARAAEIIASRLNGGGKLAYAAAGSSGLMALADAL
ELPGTFGIQRDRIAILIAGGDEAFKALAGGPEDDTEEATAAVAKAGIGAGDCLIALSASGTTPYAVRAIEDARRRGAATI
GIANNKDSALLRQAETAILLETPPEVIAGSTRMGAGTAQKIALNMLSTLTAVHLGHVHDGYMVNLMADNIKLRDRAARIV
AAISGRDRDEAARLLEKSGGAVKTAILLAAGADSADAAEKLLEGTGQKLRPALSAIEGSKGSKASVLIKTEPEKGQQGD
>Mature_318_residues
AETRTEALHRNAEGLDIQAPEAILVSLADAQIEAAKAVRNAIPAIARAAEIIASRLNGGGKLAYAAAGSSGLMALADALE
LPGTFGIQRDRIAILIAGGDEAFKALAGGPEDDTEEATAAVAKAGIGAGDCLIALSASGTTPYAVRAIEDARRRGAATIG
IANNKDSALLRQAETAILLETPPEVIAGSTRMGAGTAQKIALNMLSTLTAVHLGHVHDGYMVNLMADNIKLRDRAARIVA
AISGRDRDEAARLLEKSGGAVKTAILLAAGADSADAAEKLLEGTGQKLRPALSAIEGSKGSKASVLIKTEPEKGQQGD

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=256, Percent_Identity=37.890625, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32493; Mature: 32362

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETRTEALHRNAEGLDIQAPEAILVSLADAQIEAAKAVRNAIPAIARAAEIIASRLNGG
CCCCHHHHHHCCCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKLAYAAAGSSGLMALADALELPGTFGIQRDRIAILIAGGDEAFKALAGGPEDDTEEATA
CEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCHHHHHH
AVAKAGIGAGDCLIALSASGTTPYAVRAIEDARRRGAATIGIANNKDSALLRQAETAILL
HHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCEEEE
ETPPEVIAGSTRMGAGTAQKIALNMLSTLTAVHLGHVHDGYMVNLMADNIKLRDRAARIV
ECCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEHHHHHHHHH
AAISGRDRDEAARLLEKSGGAVKTAILLAAGADSADAAEKLLEGTGQKLRPALSAIEGSK
HHHCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCC
GSKASVLIKTEPEKGQQGD
CCCEEEEEEECCCCCCCCC
>Mature Secondary Structure 
AETRTEALHRNAEGLDIQAPEAILVSLADAQIEAAKAVRNAIPAIARAAEIIASRLNGG
CCCHHHHHHCCCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKLAYAAAGSSGLMALADALELPGTFGIQRDRIAILIAGGDEAFKALAGGPEDDTEEATA
CEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCHHHHHH
AVAKAGIGAGDCLIALSASGTTPYAVRAIEDARRRGAATIGIANNKDSALLRQAETAILL
HHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCEEEE
ETPPEVIAGSTRMGAGTAQKIALNMLSTLTAVHLGHVHDGYMVNLMADNIKLRDRAARIV
ECCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEHHHHHHHHH
AAISGRDRDEAARLLEKSGGAVKTAILLAAGADSADAAEKLLEGTGQKLRPALSAIEGSK
HHHCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCC
GSKASVLIKTEPEKGQQGD
CCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA