Click here to switch to the map view.

The map label for this gene is cat [H]

Identifier: 13473942

GI number: 13473942

Start: 3733124

End: 3733699

Strand: Reverse

Name: cat [H]

Synonym: mll4701

Alternate gene names: 13473942

Gene position: 3733699-3733124 (Counterclockwise)

Preceding gene: 13473943

Following gene: 13473941

Centisome position: 53.07

GC content: 57.12

Gene sequence:

>576_bases
ATGTCAAGATTATCGCTGTGGCTGCGGGCTAGCAGGCTCCTCCCGCCGAAAAACCCGCTGCCTCCATTTGTTACGTTGGG
TCGGTACTCGCACGGCGTTCATAAAGGGTCTTTCCTGTTCCTCTCTGAGGAAGCCCCTGTGAAGATTGGCGCTTTCTGCG
CCATCGCGGCGGAAGTTCTGTTCATTTGTCACGCCGACCATCCGACGGAGACAGCGTCGAACTTTGGATTGCAGGACCAG
ATCCTGAAAACCAAAAAGACGATTGAATACCTGCGGACCAAAGGGCCGATTGTCTTGGGAAACGATGTCTGGGTGGGAGC
AAGGGCGACCATCCTATCGGGAGTCACTATTGGTGATGGCGCCGTGGTTGCGGCATGCAGTGTGGTTACCAAGGACGTAC
CGCCCTATGCGATAGTGGCCGGCAACCCGGCAAAGCTAATTAGATACCGCTTTCCCGCCGACACTATCGCGGCCCTGCGG
GAGATCCGCTGGTGGGACTGGCCCATCGAACGCATCAAACAGGAGAAGTCAGCCTTCGAGTTGCCCGCGGAGGAATTCGT
TCGCCGCTTCAGCTGA

Upstream 100 bases:

>100_bases
GAGGTAGCCTAGCGTCGACGGGACCGCGCCCCGGCGATCGGTTTCGAGTTGCTCTATGCATTGACCCGTTTCAGAAGGGT
CGCGCTTTAAGGACGTTCAC

Downstream 100 bases:

>100_bases
CGACTGAGCCTTATGGCTGCGCTTTTCTAGATCGCATAGGTCGGAGTGCCGGCATTCCTGGCGATGATAAAGACCAAGAT
TCCGAAACAGGCGGCGATGG

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MSRLSLWLRASRLLPPKNPLPPFVTLGRYSHGVHKGSFLFLSEEAPVKIGAFCAIAAEVLFICHADHPTETASNFGLQDQ
ILKTKKTIEYLRTKGPIVLGNDVWVGARATILSGVTIGDGAVVAACSVVTKDVPPYAIVAGNPAKLIRYRFPADTIAALR
EIRWWDWPIERIKQEKSAFELPAEEFVRRFS

Sequences:

>Translated_191_residues
MSRLSLWLRASRLLPPKNPLPPFVTLGRYSHGVHKGSFLFLSEEAPVKIGAFCAIAAEVLFICHADHPTETASNFGLQDQ
ILKTKKTIEYLRTKGPIVLGNDVWVGARATILSGVTIGDGAVVAACSVVTKDVPPYAIVAGNPAKLIRYRFPADTIAALR
EIRWWDWPIERIKQEKSAFELPAEEFVRRFS
>Mature_190_residues
SRLSLWLRASRLLPPKNPLPPFVTLGRYSHGVHKGSFLFLSEEAPVKIGAFCAIAAEVLFICHADHPTETASNFGLQDQI
LKTKKTIEYLRTKGPIVLGNDVWVGARATILSGVTIGDGAVVAACSVVTKDVPPYAIVAGNPAKLIRYRFPADTIAALRE
IRWWDWPIERIKQEKSAFELPAEEFVRRFS

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786664, Length=127, Percent_Identity=37.007874015748, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1786537, Length=53, Percent_Identity=52.8301886792453, Blast_Score=67, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322243, Length=133, Percent_Identity=29.3233082706767, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 21184; Mature: 21053

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00101 HEXAPEP_TRANSFERASES ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLSLWLRASRLLPPKNPLPPFVTLGRYSHGVHKGSFLFLSEEAPVKIGAFCAIAAEVL
CCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCEEHHHHHHHHHHHH
FICHADHPTETASNFGLQDQILKTKKTIEYLRTKGPIVLGNDVWVGARATILSGVTIGDG
HEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCEEECCCEEECCHHHHHCCCEECCC
AVVAACSVVTKDVPPYAIVAGNPAKLIRYRFPADTIAALREIRWWDWPIERIKQEKSAFE
HHHHHHHHHHCCCCCEEEEECCHHHEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHC
LPAEEFVRRFS
CCHHHHHHHCC
>Mature Secondary Structure 
SRLSLWLRASRLLPPKNPLPPFVTLGRYSHGVHKGSFLFLSEEAPVKIGAFCAIAAEVL
CCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCEEHHHHHHHHHHHH
FICHADHPTETASNFGLQDQILKTKKTIEYLRTKGPIVLGNDVWVGARATILSGVTIGDG
HEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCEEECCCEEECCHHHHHCCCEECCC
AVVAACSVVTKDVPPYAIVAGNPAKLIRYRFPADTIAALREIRWWDWPIERIKQEKSAFE
HHHHHHHHHHCCCCCEEEEECCHHHEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHC
LPAEEFVRRFS
CCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2013403; 11743193; 11743194 [H]