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The map label for this gene is nreC [H]

Identifier: 13473938

GI number: 13473938

Start: 3727949

End: 3728596

Strand: Reverse

Name: nreC [H]

Synonym: mll4697

Alternate gene names: 13473938

Gene position: 3728596-3727949 (Counterclockwise)

Preceding gene: 13473939

Following gene: 13473937

Centisome position: 52.99

GC content: 55.71

Gene sequence:

>648_bases
ATGGTCGACCCGAGGATCAAGATAGTGATTGCTGACGACCATCCAATTGTCCGCAGCGGAATAAGGGCGGTGTTGGAGCA
GCGGGCGGAGTGGTGGGTTTGCGGCGAAGCTGACAATGGCGAGACAGCGGTGAGACTAGCGCGGGAGCATGCCGCAAAAA
TCGTAATCCTGGACTATAGCTTGCCAGTTCTCAACGGACTGGAAGCAACCCGAATTATCCGGCGGACAATGCCGGAAACC
GAGGTTCTGATCTACACAATGCACGAGGACGAGAGCCTCATTCGCGAAACGCTCAGGGCGGGCGCCCGTGGTTATCTGCT
GAAGATTGAAGACGACAGCGAACTTGTTGCCGCTGTCGCCGCGCTCATTCGGGGCCAAACATATTTTTCACCGCGGGTCA
GCGAATGCGTGCTTCAAGATTTCTTGGATGGCCAAAGCGACGTCACCTCCCGCAATCTGACCAACCGAGAGCGGGAGGTT
GTGCGCTTTGTCTCGGAAGGCGAGTCCAATAAGCGCATCGCAGCCCGACTAGGAGTCAGTGTTAAGACAGTGGATTCTCA
TCGGACCACCGCGATGCGTAAACTCGGTCTTCGCAATGCGGTTGATCTCGTACGCTATGCGATCCGCAACAAACTTACTT
TGCCTTGA

Upstream 100 bases:

>100_bases
CATCCGAAGGCGACCGCTTGACAGAATTGTTAAGGCAAGATGTGCCGGCCCAGCAAGAATGGAACGCAACGCAACCCAAA
CCGATCAAGAAGAGCGCGTC

Downstream 100 bases:

>100_bases
TCCGAAACATTTCCGGGATGAACCGCTCGACGGATCGCCTCTCTCGTCGCGGCGGTCCCAACAGAAGCTGCCGGTAGCGC
ATCCTCTGATGCGAACGACA

Product: two-component system response regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MVDPRIKIVIADDHPIVRSGIRAVLEQRAEWWVCGEADNGETAVRLAREHAAKIVILDYSLPVLNGLEATRIIRRTMPET
EVLIYTMHEDESLIRETLRAGARGYLLKIEDDSELVAAVAALIRGQTYFSPRVSECVLQDFLDGQSDVTSRNLTNREREV
VRFVSEGESNKRIAARLGVSVKTVDSHRTTAMRKLGLRNAVDLVRYAIRNKLTLP

Sequences:

>Translated_215_residues
MVDPRIKIVIADDHPIVRSGIRAVLEQRAEWWVCGEADNGETAVRLAREHAAKIVILDYSLPVLNGLEATRIIRRTMPET
EVLIYTMHEDESLIRETLRAGARGYLLKIEDDSELVAAVAALIRGQTYFSPRVSECVLQDFLDGQSDVTSRNLTNREREV
VRFVSEGESNKRIAARLGVSVKTVDSHRTTAMRKLGLRNAVDLVRYAIRNKLTLP
>Mature_215_residues
MVDPRIKIVIADDHPIVRSGIRAVLEQRAEWWVCGEADNGETAVRLAREHAAKIVILDYSLPVLNGLEATRIIRRTMPET
EVLIYTMHEDESLIRETLRAGARGYLLKIEDDSELVAAVAALIRGQTYFSPRVSECVLQDFLDGQSDVTSRNLTNREREV
VRFVSEGESNKRIAARLGVSVKTVDSHRTTAMRKLGLRNAVDLVRYAIRNKLTLP

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=208, Percent_Identity=33.6538461538462, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=34.5, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788521, Length=196, Percent_Identity=33.1632653061224, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788546, Length=206, Percent_Identity=32.0388349514563, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=28.5, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788712, Length=204, Percent_Identity=28.4313725490196, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=31.1475409836066, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24220; Mature: 24220

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDPRIKIVIADDHPIVRSGIRAVLEQRAEWWVCGEADNGETAVRLAREHAAKIVILDYS
CCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCEEEEEECC
LPVLNGLEATRIIRRTMPETEVLIYTMHEDESLIRETLRAGARGYLLKIEDDSELVAAVA
CCHHCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
ALIRGQTYFSPRVSECVLQDFLDGQSDVTSRNLTNREREVVRFVSEGESNKRIAARLGVS
HHHCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHCCCCCCEEHHHHCCE
VKTVDSHRTTAMRKLGLRNAVDLVRYAIRNKLTLP
EEECCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVDPRIKIVIADDHPIVRSGIRAVLEQRAEWWVCGEADNGETAVRLAREHAAKIVILDYS
CCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCEEEEEECC
LPVLNGLEATRIIRRTMPETEVLIYTMHEDESLIRETLRAGARGYLLKIEDDSELVAAVA
CCHHCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
ALIRGQTYFSPRVSECVLQDFLDGQSDVTSRNLTNREREVVRFVSEGESNKRIAARLGVS
HHHCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHCCCCCCEEHHHHCCE
VKTVDSHRTTAMRKLGLRNAVDLVRYAIRNKLTLP
EEECCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]