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The map label for this gene is degS [H]

Identifier: 13473841

GI number: 13473841

Start: 3631422

End: 3632861

Strand: Reverse

Name: degS [H]

Synonym: mll4568

Alternate gene names: 13473841

Gene position: 3632861-3631422 (Counterclockwise)

Preceding gene: 13473847

Following gene: 13473840

Centisome position: 51.63

GC content: 64.72

Gene sequence:

>1440_bases
ATGTGCCGATATCGCCCAGCTGTTCGATGGAAGGGCGGTCAGGGGATCATGATTCGTATTCTGCAGAATTTGGCGCGGCG
CTGGAGCGAGCTTTCGCTTGCCCTGCAATTCCTCGTTGCGGGAGGCTTTGGCCTTCTGGCCGTCATGCTGGTGGTGGGCG
CCTGGGTGACGTCGCAGATCCGGGACGGCGTCATCCGCAATTCGGCCGCCACGACGGCGCTCTATGTCGACAGCGTGATC
GCGCCGCTGCTGCCAGACCTGCGCAAGAGCGAGACGCTCAGCGAGTCCGTCAAGCAGGCGCTCGACGAGACGCTCGGCCA
GGGCGCGCTCGGCAAGCGCCTGGCCTCGTTCAGGCTCTGGCGCCGCGACGGCACCGTGCTCTATGCCAAGGACCCGACGT
TGATCGGCCGCCGCTTCGAACTGACCGACGATCTGCGGTCCGCCTTCCAGGGCAACGTCACCGCTCAATTCGATACGTTC
GACGAAACCGAAGGCAAGGAGCAGACCGTCGGCGTGCCGTTGCTGGAGATCTATAATCCCGTGCGCGAACCCTGGTCCGG
CGAGGTGGTGGCCGTCACCGAATTCTTCGAGATCGCCACTGATTTCAAAGCCACGCTGGCCTCTGCCCTGCTGTCGAGCT
GGCTGATCGTGGCCGGCACCACCCTGACGGCCTTTCTGCTCCTGTCGAGCATCGTGCTGCGCGCCAGCCGCACCATCGAC
GATCAGCGCGGGGCGCTGCGCCGCCAAGTGTCGGAGCTGCAGGGGCTGGTGACGCAAAACAGCGCCTTGCGGCAGCGTGT
GCAGCGGGCGTCCCGCCGCGCCACCGCACTCAACGAACGATATTTGCGCCGGATCGGCGCCGACCTGCATGATGGACCGG
CACAGCTCGTGGCCCTGGCGGCGCTGCGCATGGACAGCCCGGTATTCTCCGGCGAGGGCCATTGGGGCGAAAACCGCTCG
ACCGAGGTCGCGATGATCCGCAAGACGCTGGAGGATGCGATGCGCGAAATACGCGGTATCTGCACCGGTCTCGTCCTGCC
GCAGATAGAAACGGCTGCGGCAACGGACATATTGCGGCTGGCCGTCGACGAACATGAGCGCCGGACGGGAACGTCGGTGA
CGCTCACACTGCCCAGGCATTTGCCTGAACTTGGCCCTTCCGAGAAGATCAGCATCTATCGTTTCGTGCAGGAAGGGCTG
AACAATGCCTATCGCCACGGGCGGGCCAAGGATCAGGCGGTGCGGGCCGGGATGAAGAATGGCAGGCTTTTTGTCGAAGT
GTCGGATGGCGGGCCGGGTTTCGATCCGGCGCGGGTCGACGGATTGGGGCTCGCCGGCCTCAGGGAGCGGGTCGAAAGCA
TTGGCGGCCAGTTCGAGACCGTGACCGGAGCGCAAGGCACGCGATTGGTGATCAGTCTTTCGGTCGAGGAGCAAGCATGA

Upstream 100 bases:

>100_bases
TGCCGCCGCATGTCCCGCCGACCTTGTTTCCGAAGCGCCTTGAGACGTCAAGCGACCTCCTTTCTAACGAAGGCCTTGGC
AACGGCAAGGCTGAGGCTCA

Downstream 100 bases:

>100_bases
TTGGCACTATCCGCATCGCTATTGTCGACGATCATCCGCTGTTTCGCGAAGGCGTGACGCGCAGCCTGTCGGAGATCGGA
GGTTTCGAGATCGTCGGCGA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MCRYRPAVRWKGGQGIMIRILQNLARRWSELSLALQFLVAGGFGLLAVMLVVGAWVTSQIRDGVIRNSAATTALYVDSVI
APLLPDLRKSETLSESVKQALDETLGQGALGKRLASFRLWRRDGTVLYAKDPTLIGRRFELTDDLRSAFQGNVTAQFDTF
DETEGKEQTVGVPLLEIYNPVREPWSGEVVAVTEFFEIATDFKATLASALLSSWLIVAGTTLTAFLLLSSIVLRASRTID
DQRGALRRQVSELQGLVTQNSALRQRVQRASRRATALNERYLRRIGADLHDGPAQLVALAALRMDSPVFSGEGHWGENRS
TEVAMIRKTLEDAMREIRGICTGLVLPQIETAAATDILRLAVDEHERRTGTSVTLTLPRHLPELGPSEKISIYRFVQEGL
NNAYRHGRAKDQAVRAGMKNGRLFVEVSDGGPGFDPARVDGLGLAGLRERVESIGGQFETVTGAQGTRLVISLSVEEQA

Sequences:

>Translated_479_residues
MCRYRPAVRWKGGQGIMIRILQNLARRWSELSLALQFLVAGGFGLLAVMLVVGAWVTSQIRDGVIRNSAATTALYVDSVI
APLLPDLRKSETLSESVKQALDETLGQGALGKRLASFRLWRRDGTVLYAKDPTLIGRRFELTDDLRSAFQGNVTAQFDTF
DETEGKEQTVGVPLLEIYNPVREPWSGEVVAVTEFFEIATDFKATLASALLSSWLIVAGTTLTAFLLLSSIVLRASRTID
DQRGALRRQVSELQGLVTQNSALRQRVQRASRRATALNERYLRRIGADLHDGPAQLVALAALRMDSPVFSGEGHWGENRS
TEVAMIRKTLEDAMREIRGICTGLVLPQIETAAATDILRLAVDEHERRTGTSVTLTLPRHLPELGPSEKISIYRFVQEGL
NNAYRHGRAKDQAVRAGMKNGRLFVEVSDGGPGFDPARVDGLGLAGLRERVESIGGQFETVTGAQGTRLVISLSVEEQA
>Mature_479_residues
MCRYRPAVRWKGGQGIMIRILQNLARRWSELSLALQFLVAGGFGLLAVMLVVGAWVTSQIRDGVIRNSAATTALYVDSVI
APLLPDLRKSETLSESVKQALDETLGQGALGKRLASFRLWRRDGTVLYAKDPTLIGRRFELTDDLRSAFQGNVTAQFDTF
DETEGKEQTVGVPLLEIYNPVREPWSGEVVAVTEFFEIATDFKATLASALLSSWLIVAGTTLTAFLLLSSIVLRASRTID
DQRGALRRQVSELQGLVTQNSALRQRVQRASRRATALNERYLRRIGADLHDGPAQLVALAALRMDSPVFSGEGHWGENRS
TEVAMIRKTLEDAMREIRGICTGLVLPQIETAAATDILRLAVDEHERRTGTSVTLTLPRHLPELGPSEKISIYRFVQEGL
NNAYRHGRAKDQAVRAGMKNGRLFVEVSDGGPGFDPARVDGLGLAGLRERVESIGGQFETVTGAQGTRLVISLSVEEQA

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=91, Percent_Identity=34.0659340659341, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52592; Mature: 52592

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRYRPAVRWKGGQGIMIRILQNLARRWSELSLALQFLVAGGFGLLAVMLVVGAWVTSQI
CCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RDGVIRNSAATTALYVDSVIAPLLPDLRKSETLSESVKQALDETLGQGALGKRLASFRLW
HHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHE
RRDGTVLYAKDPTLIGRRFELTDDLRSAFQGNVTAQFDTFDETEGKEQTVGVPLLEIYNP
ECCCEEEEECCCCCCCCEECCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHH
VREPWSGEVVAVTEFFEIATDFKATLASALLSSWLIVAGTTLTAFLLLSSIVLRASRTID
HCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DQRGALRRQVSELQGLVTQNSALRQRVQRASRRATALNERYLRRIGADLHDGPAQLVALA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ALRMDSPVFSGEGHWGENRSTEVAMIRKTLEDAMREIRGICTGLVLPQIETAAATDILRL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AVDEHERRTGTSVTLTLPRHLPELGPSEKISIYRFVQEGLNNAYRHGRAKDQAVRAGMKN
HHHHHHHCCCCEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCC
GRLFVEVSDGGPGFDPARVDGLGLAGLRERVESIGGQFETVTGAQGTRLVISLSVEEQA
CEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MCRYRPAVRWKGGQGIMIRILQNLARRWSELSLALQFLVAGGFGLLAVMLVVGAWVTSQI
CCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RDGVIRNSAATTALYVDSVIAPLLPDLRKSETLSESVKQALDETLGQGALGKRLASFRLW
HHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHE
RRDGTVLYAKDPTLIGRRFELTDDLRSAFQGNVTAQFDTFDETEGKEQTVGVPLLEIYNP
ECCCEEEEECCCCCCCCEECCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHH
VREPWSGEVVAVTEFFEIATDFKATLASALLSSWLIVAGTTLTAFLLLSSIVLRASRTID
HCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DQRGALRRQVSELQGLVTQNSALRQRVQRASRRATALNERYLRRIGADLHDGPAQLVALA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ALRMDSPVFSGEGHWGENRSTEVAMIRKTLEDAMREIRGICTGLVLPQIETAAATDILRL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AVDEHERRTGTSVTLTLPRHLPELGPSEKISIYRFVQEGLNNAYRHGRAKDQAVRAGMKN
HHHHHHHCCCCEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCC
GRLFVEVSDGGPGFDPARVDGLGLAGLRERVESIGGQFETVTGAQGTRLVISLSVEEQA
CEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]