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The map label for this gene is mprF [H]

Identifier: 13473834

GI number: 13473834

Start: 3624681

End: 3625718

Strand: Reverse

Name: mprF [H]

Synonym: mll4560

Alternate gene names: 13473834

Gene position: 3625718-3624681 (Counterclockwise)

Preceding gene: 13473837

Following gene: 13473833

Centisome position: 51.53

GC content: 62.14

Gene sequence:

>1038_bases
ATGCCCTCCTTGCGGATCTATTTCGACAAAATCCTCGAGCGTGCCTCGCCCAAGGTCGAGCGCCAGGCGCTAACGCATGT
CGAACGCCTGGCAATGGTTCGCCGCCATGGCGACTTCTCGCTCGCCTATTCGACTGCCGTACAGCAGAAGCTTTCCTATT
TTGGCGACGCCGACGGCTACATCGCCTTCGGCACCAAGATGAAGCATCATTTCGCGCTTGGCGACCCGGTGGCGGCACCG
GCCCGGCGGCCCGACTTTATCAAGCGCTTCGTCGAGACCGCCGGCGACCCTTGGTTCGTGCAGATCAGCGAGGAGACCGC
GCGCGTGCTGGCCGGGCTCGGCTACAAGGTCAACCGGCTGGGCATCGACACAAGCCTCGTCCTGTCCGAGCATGACTTTT
CCGGCAAGCGCAACGAGACCGTGCGCTATTCCGAACGCTGGCTCTTGAAGAAGGGCTTTTCTTTCGAGGAAGACAAGCGG
ACGGTATTCCTCGACGAAATCGCCCGGCTGTCCGAGAACTGGCGCGGCGACCGCATCGTCAAGCGCTGGGAGATGGGCTT
TCTCAACCGCCCGTTCTACGATCAGCTCGGCACCGACATGCGCCGCTTCGTCCTGCATGGTCCCGATGGCGAGCTGATCG
CGCTGCTCGATTTCGATCCGCTGTTTCGCGACGGCAAGGTCATCGGCTACACCACCGCCTTCAAGCGCAAGCACATCGAT
GCCTCGCCGCATGCCGAGATCGGCCTGACCAAATTCGCCGTCGACCGGTTTCGCGAAGAGGGCATCTCGGTGGTCACGCT
GGGCCTGTCGCCGCTCGTCGACGTCACCCCCAGCGGATTTGCCGAGAGCGATTTCTGGCGCAACACTTTTCAGCGCGCCT
ACGCTTCGCCATGGGTCAACCGCCGCAGGTTCAACCTGCAGGGCCAGGCGGCATTCAAGCGCCGCTTCCATGGCAAGGAA
GAGCCGGTGTACATTGCTTTCCGCAAGGGAACCTATGTCGAGATGCTGGGCCTGCTGCGGCTGGTGAAAGCGATCTAG

Upstream 100 bases:

>100_bases
CCGCGGCGATTTCGGCTTCCCGTGAAAAATCAAGGCGCCATGGCGCGTCCGGCGTGCCGAACGGCATGTCGCGCCACAGA
CGGCACGCGGAATCTCGACC

Downstream 100 bases:

>100_bases
GAGGCCCCGGCGCGGTCCTGGTCAAGCCTTTCATTCGTCATCCTTCTCGCCGCGTCGCTCCGCTCCTTGCCTCGCGCTGG
GATGACGGACGCCGGGTTGC

Product: hypothetical protein

Products: NA

Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MPSLRIYFDKILERASPKVERQALTHVERLAMVRRHGDFSLAYSTAVQQKLSYFGDADGYIAFGTKMKHHFALGDPVAAP
ARRPDFIKRFVETAGDPWFVQISEETARVLAGLGYKVNRLGIDTSLVLSEHDFSGKRNETVRYSERWLLKKGFSFEEDKR
TVFLDEIARLSENWRGDRIVKRWEMGFLNRPFYDQLGTDMRRFVLHGPDGELIALLDFDPLFRDGKVIGYTTAFKRKHID
ASPHAEIGLTKFAVDRFREEGISVVTLGLSPLVDVTPSGFAESDFWRNTFQRAYASPWVNRRRFNLQGQAAFKRRFHGKE
EPVYIAFRKGTYVEMLGLLRLVKAI

Sequences:

>Translated_345_residues
MPSLRIYFDKILERASPKVERQALTHVERLAMVRRHGDFSLAYSTAVQQKLSYFGDADGYIAFGTKMKHHFALGDPVAAP
ARRPDFIKRFVETAGDPWFVQISEETARVLAGLGYKVNRLGIDTSLVLSEHDFSGKRNETVRYSERWLLKKGFSFEEDKR
TVFLDEIARLSENWRGDRIVKRWEMGFLNRPFYDQLGTDMRRFVLHGPDGELIALLDFDPLFRDGKVIGYTTAFKRKHID
ASPHAEIGLTKFAVDRFREEGISVVTLGLSPLVDVTPSGFAESDFWRNTFQRAYASPWVNRRRFNLQGQAAFKRRFHGKE
EPVYIAFRKGTYVEMLGLLRLVKAI
>Mature_344_residues
PSLRIYFDKILERASPKVERQALTHVERLAMVRRHGDFSLAYSTAVQQKLSYFGDADGYIAFGTKMKHHFALGDPVAAPA
RRPDFIKRFVETAGDPWFVQISEETARVLAGLGYKVNRLGIDTSLVLSEHDFSGKRNETVRYSERWLLKKGFSFEEDKRT
VFLDEIARLSENWRGDRIVKRWEMGFLNRPFYDQLGTDMRRFVLHGPDGELIALLDFDPLFRDGKVIGYTTAFKRKHIDA
SPHAEIGLTKFAVDRFREEGISVVTLGLSPLVDVTPSGFAESDFWRNTFQRAYASPWVNRRRFNLQGQAAFKRRFHGKEE
PVYIAFRKGTYVEMLGLLRLVKAI

Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contribu

COG id: COG2898

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LPG synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR022791 [H]

Pfam domain/function: PF03706 UPF0104 [H]

EC number: =2.3.2.3 [H]

Molecular weight: Translated: 39797; Mature: 39666

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLRIYFDKILERASPKVERQALTHVERLAMVRRHGDFSLAYSTAVQQKLSYFGDADGY
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCE
IAFGTKMKHHFALGDPVAAPARRPDFIKRFVETAGDPWFVQISEETARVLAGLGYKVNRL
EEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCEEEEE
GIDTSLVLSEHDFSGKRNETVRYSERWLLKKGFSFEEDKRTVFLDEIARLSENWRGDRIV
CCCEEEEEECCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCHHH
KRWEMGFLNRPFYDQLGTDMRRFVLHGPDGELIALLDFDPLFRDGKVIGYTTAFKRKHID
HHHHHCCCCCCHHHHHCHHHHHHEEECCCCCEEEEEECCCCCCCCEEEEEEHHHHHHCCC
ASPHAEIGLTKFAVDRFREEGISVVTLGLSPLVDVTPSGFAESDFWRNTFQRAYASPWVN
CCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCC
RRRFNLQGQAAFKRRFHGKEEPVYIAFRKGTYVEMLGLLRLVKAI
CEEECCCCHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHC
>Mature Secondary Structure 
PSLRIYFDKILERASPKVERQALTHVERLAMVRRHGDFSLAYSTAVQQKLSYFGDADGY
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCE
IAFGTKMKHHFALGDPVAAPARRPDFIKRFVETAGDPWFVQISEETARVLAGLGYKVNRL
EEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCEEEEE
GIDTSLVLSEHDFSGKRNETVRYSERWLLKKGFSFEEDKRTVFLDEIARLSENWRGDRIV
CCCEEEEEECCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCHHH
KRWEMGFLNRPFYDQLGTDMRRFVLHGPDGELIALLDFDPLFRDGKVIGYTTAFKRKHID
HHHHHCCCCCCHHHHHCHHHHHHEEECCCCCEEEEEECCCCCCCCEEEEEEHHHHHHCCC
ASPHAEIGLTKFAVDRFREEGISVVTLGLSPLVDVTPSGFAESDFWRNTFQRAYASPWVN
CCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCC
RRRFNLQGQAAFKRRFHGKEEPVYIAFRKGTYVEMLGLLRLVKAI
CEEECCCCHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]