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The map label for this gene is yafC [H]

Identifier: 13473471

GI number: 13473471

Start: 3262954

End: 3263859

Strand: Reverse

Name: yafC [H]

Synonym: mll4082

Alternate gene names: 13473471

Gene position: 3263859-3262954 (Counterclockwise)

Preceding gene: 13473475

Following gene: 13473467

Centisome position: 46.39

GC content: 67.99

Gene sequence:

>906_bases
ATGGCCAGACCCGACATCAACCGCTCCGGCGAGATCGAAGTCTTCGTGCGCGTTGTCGAGGCGGGCAGCTTCTCGGCGGC
TGCGCGCACGTTGCGCATGACGCCATCGGCCGTCAGCAAACTGATCGCGCGTCTGGAGGCTCGGCTCGGCGCGCGGCTGG
TTAGCCGTTCGACACGCAAGCTGCAGCTGACGCCGGAGGGAACGGCGTTCTACGACAGCGGATTGCGTATCCTGGCCGAC
ATGGCAGCGGCCGAGCGCGAGGCGGCGGCGGGTGCCGCACCACGCGGGAGGCTGCGCGTCAACACCTACGTGCCCTTCGG
CGTGCACCGGCTGATCCCGCTCTTGCCGCGCTTCCTTGAGCGCTATTCCGAGATATCCGTCGATCTGGTGCTGACCGACA
GCGTCATCGACCTGATGGCCGAACGTGCCGATGTCGCCATCCGCGCCGGGCCGCTCGGCGAATCGCGGCTGGTGGCGCGC
AAGCTCGGACAGAGCCTGGTGGTGGTGGTTGCGGCCCCGTCCTATCTCGAAGCGCACGGCAAGCCTCTGACGCCGGCCGA
CCTCGATGGGCATAATCTCATGGGCTTCGGCTTCGTCAGGCATATCGATGGCTGGCCGTTTGTCGACGCTGAAGGCCGCG
CGGTCATGGTCCCGATCACCGGCAACACGCTGGTCAGCGACGGCGAGGCGATGCGGCTGATGACGCTGGCCGGAGCCGGC
ATCTCCCGGCTGGCGCGCTGGCATGTCGCGGCCGATATCGCTGCCGGGCGGCTGGTAGCACTGCTGGAGGATTTCAATCC
GGGCGACGAGGAGGCGACCCACGCCGTCTATGTCGGCCAGGGCCGGCATCTGCCGGCGCGGGTGCGGGCCTTTCTCGATT
TTCTGGCCGAGACCGTGCGGCTCTGA

Upstream 100 bases:

>100_bases
AGCGCCTTGTCCAAACCGCGCTCCGGCCCGAAAGATCGTGTCGCCATGCACTGTGAACCAGACTTGTGTTGGGCACATTT
TCTGTGAAATAGATTCACAA

Downstream 100 bases:

>100_bases
GGAAACGCAGGTTTTCAAGGTCCGTTCGACAACCCGACAGGGGCGGGATATGGAATCCCCGTCCGCTCATCATCACGGGA
TCGCAACGATGCCGTCCCGA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MARPDINRSGEIEVFVRVVEAGSFSAAARTLRMTPSAVSKLIARLEARLGARLVSRSTRKLQLTPEGTAFYDSGLRILAD
MAAAEREAAAGAAPRGRLRVNTYVPFGVHRLIPLLPRFLERYSEISVDLVLTDSVIDLMAERADVAIRAGPLGESRLVAR
KLGQSLVVVVAAPSYLEAHGKPLTPADLDGHNLMGFGFVRHIDGWPFVDAEGRAVMVPITGNTLVSDGEAMRLMTLAGAG
ISRLARWHVAADIAAGRLVALLEDFNPGDEEATHAVYVGQGRHLPARVRAFLDFLAETVRL

Sequences:

>Translated_301_residues
MARPDINRSGEIEVFVRVVEAGSFSAAARTLRMTPSAVSKLIARLEARLGARLVSRSTRKLQLTPEGTAFYDSGLRILAD
MAAAEREAAAGAAPRGRLRVNTYVPFGVHRLIPLLPRFLERYSEISVDLVLTDSVIDLMAERADVAIRAGPLGESRLVAR
KLGQSLVVVVAAPSYLEAHGKPLTPADLDGHNLMGFGFVRHIDGWPFVDAEGRAVMVPITGNTLVSDGEAMRLMTLAGAG
ISRLARWHVAADIAAGRLVALLEDFNPGDEEATHAVYVGQGRHLPARVRAFLDFLAETVRL
>Mature_300_residues
ARPDINRSGEIEVFVRVVEAGSFSAAARTLRMTPSAVSKLIARLEARLGARLVSRSTRKLQLTPEGTAFYDSGLRILADM
AAAEREAAAGAAPRGRLRVNTYVPFGVHRLIPLLPRFLERYSEISVDLVLTDSVIDLMAERADVAIRAGPLGESRLVARK
LGQSLVVVVAAPSYLEAHGKPLTPADLDGHNLMGFGFVRHIDGWPFVDAEGRAVMVPITGNTLVSDGEAMRLMTLAGAGI
SRLARWHVAADIAAGRLVALLEDFNPGDEEATHAVYVGQGRHLPARVRAFLDFLAETVRL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=39.6610169491525, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=33.1058020477816, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=31.1864406779661, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787128, Length=293, Percent_Identity=29.3515358361775, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=30.9278350515464, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=28.125, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1787589, Length=303, Percent_Identity=27.0627062706271, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789173, Length=254, Percent_Identity=30.3149606299213, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788706, Length=295, Percent_Identity=25.0847457627119, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790262, Length=237, Percent_Identity=27.8481012658228, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787806, Length=244, Percent_Identity=27.4590163934426, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI157672245, Length=178, Percent_Identity=32.0224719101124, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32491; Mature: 32360

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPDINRSGEIEVFVRVVEAGSFSAAARTLRMTPSAVSKLIARLEARLGARLVSRSTRK
CCCCCCCCCCCEEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCE
LQLTPEGTAFYDSGLRILADMAAAEREAAAGAAPRGRLRVNTYVPFGVHRLIPLLPRFLE
EEECCCCCEEHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
RYSEISVDLVLTDSVIDLMAERADVAIRAGPLGESRLVARKLGQSLVVVVAAPSYLEAHG
HHHHCEEEEEEHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCCEEEEEEECCHHHHHCC
KPLTPADLDGHNLMGFGFVRHIDGWPFVDAEGRAVMVPITGNTLVSDGEAMRLMTLAGAG
CCCCCCCCCCCCEEHHHHHHHCCCCCEECCCCCEEEEEECCCEEECCCCCEEEEEHHCCC
ISRLARWHVAADIAAGRLVALLEDFNPGDEEATHAVYVGQGRHLPARVRAFLDFLAETVR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure 
ARPDINRSGEIEVFVRVVEAGSFSAAARTLRMTPSAVSKLIARLEARLGARLVSRSTRK
CCCCCCCCCCEEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCE
LQLTPEGTAFYDSGLRILADMAAAEREAAAGAAPRGRLRVNTYVPFGVHRLIPLLPRFLE
EEECCCCCEEHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
RYSEISVDLVLTDSVIDLMAERADVAIRAGPLGESRLVARKLGQSLVVVVAAPSYLEAHG
HHHHCEEEEEEHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCCEEEEEEECCHHHHHCC
KPLTPADLDGHNLMGFGFVRHIDGWPFVDAEGRAVMVPITGNTLVSDGEAMRLMTLAGAG
CCCCCCCCCCCCEEHHHHHHHCCCCCEECCCCCEEEEEECCCEEECCCCCEEEEEHHCCC
ISRLARWHVAADIAAGRLVALLEDFNPGDEEATHAVYVGQGRHLPARVRAFLDFLAETVR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]