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The map label for this gene is intZ [H]

Identifier: 13473443

GI number: 13473443

Start: 3230719

End: 3231915

Strand: Reverse

Name: intZ [H]

Synonym: mll4043

Alternate gene names: 13473443

Gene position: 3231915-3230719 (Counterclockwise)

Preceding gene: 13473447

Following gene: 13473442

Centisome position: 45.93

GC content: 61.4

Gene sequence:

>1197_bases
ATGACGGCAAAGGCGAAAATCACGACAGACAAGGCGCTGGCGGTGCTTGCCGGTCCGGGCGAAATCTATTCTGACAGCAT
CAAAGGCACCGGGCTTTATCTGTTTGTCACCAAGACAGGCACCCGGCGGTGGGTTTTCATTTACAGCCGCCACGGTAAGC
GCCGCGAACTGGCGCTCGGGGTAGTCGATGGCCCCAAGGGTATTTCCTTGAAAGACGCTCGCAACCAAGCCCGTGCGTAT
CAGGCAACGCTCGCGCAAGGTGGTGATCCCTGGGACGACGCGCGCCGCGAAAAGGAACAGCAAATCAAGGCGCAGACGTT
CGGCGAATTCGCGGATACGTTTATTGCGGAACAGGCCAAGGGCTTCCGAAACGCGAAGCACATTGCGCAGTGGAAAATGA
CGATGAAGGTGTACGCGAAGCGCCTTCAACGCCTCCCCCTCGACGGGATCGAAACGGCCGACGTGCTGGCCGTGCTGCAA
CCTGTCTGGACGGCGAAACCCGAAACTGCGAAGCGGACACAGGGCCGTATTGAACGCATTCTTGACGCGGCAAAGGCGCA
AGGTTTGCGCAAGGGGGAGAACCCGGCTCGATGGCGCGGCCACCTCGATAAGCTACTCTCTCGGCAGAGTAAGCTATCGC
GCGGGCATCACGCCGCGCTTCCTTATGCGAGTGTTCCCGCCTTCGTAGCCAAATTGCGCAAGTCTGACGCGGTGTCCTCG
CTGGCACTGGAATTCCTCATCCTGACAGCCGCTCGCACCGGGGAAGTGATCTTGGCCCGCTGGAACGAAATCGACGCGAT
TAACGCCGTGTGGACGGTTCCCGCCGCGCGGATGAAAGCCGGACGCGAGCATCGTGTCCCGCTGTCAGCACGCGCGCTGG
AAATCCTAAACGCCGTAGTTCCTGTCCGCACTGCGCCTGACGGCTTCATCTTCCCAGGGGCCAAAGAGGGCAAGGGGCTC
TCCCAAATGGCGCTGGCTATGATGCTGCGGCAATGCGGGGAAGATGACGTGACGGTGCACGGCTTTCGGTCGGCGTTTCG
GGATTGGGCGGCGGAGGAAACCGACGCTCCTCGCGAAGTCGCCGAAGCGGCGCTGGCCCACGCGGTAGGCGACGCGACAG
AGCGTGCATATCGTCGTGGCGACGCGTTGGCGAAGCGACGTGTGTTGATGGATGCTTGGTCAGCGTTCTGCACCTGA

Upstream 100 bases:

>100_bases
AAGCGTTTTTTCAAGAAACATGTCCGCTGGCGTTCGGTCGTGTTTGCCTCTTTCCGCCAGTTTGGTTTATGGTTGCCTTT
ATGTTTCTAGGAGGCGGGCC

Downstream 100 bases:

>100_bases
CAAGTCTTGTCAGCGCTGACAGGACTTGCCAGCACTGACAAATCACAGCGAAGCAACAGATGGTGTGTCTCGTACAATAG
ACAGTTGTTCCAGTCGAAGT

Product: phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTAKAKITTDKALAVLAGPGEIYSDSIKGTGLYLFVTKTGTRRWVFIYSRHGKRRELALGVVDGPKGISLKDARNQARAY
QATLAQGGDPWDDARREKEQQIKAQTFGEFADTFIAEQAKGFRNAKHIAQWKMTMKVYAKRLQRLPLDGIETADVLAVLQ
PVWTAKPETAKRTQGRIERILDAAKAQGLRKGENPARWRGHLDKLLSRQSKLSRGHHAALPYASVPAFVAKLRKSDAVSS
LALEFLILTAARTGEVILARWNEIDAINAVWTVPAARMKAGREHRVPLSARALEILNAVVPVRTAPDGFIFPGAKEGKGL
SQMALAMMLRQCGEDDVTVHGFRSAFRDWAAEETDAPREVAEAALAHAVGDATERAYRRGDALAKRRVLMDAWSAFCT

Sequences:

>Translated_398_residues
MTAKAKITTDKALAVLAGPGEIYSDSIKGTGLYLFVTKTGTRRWVFIYSRHGKRRELALGVVDGPKGISLKDARNQARAY
QATLAQGGDPWDDARREKEQQIKAQTFGEFADTFIAEQAKGFRNAKHIAQWKMTMKVYAKRLQRLPLDGIETADVLAVLQ
PVWTAKPETAKRTQGRIERILDAAKAQGLRKGENPARWRGHLDKLLSRQSKLSRGHHAALPYASVPAFVAKLRKSDAVSS
LALEFLILTAARTGEVILARWNEIDAINAVWTVPAARMKAGREHRVPLSARALEILNAVVPVRTAPDGFIFPGAKEGKGL
SQMALAMMLRQCGEDDVTVHGFRSAFRDWAAEETDAPREVAEAALAHAVGDATERAYRRGDALAKRRVLMDAWSAFCT
>Mature_397_residues
TAKAKITTDKALAVLAGPGEIYSDSIKGTGLYLFVTKTGTRRWVFIYSRHGKRRELALGVVDGPKGISLKDARNQARAYQ
ATLAQGGDPWDDARREKEQQIKAQTFGEFADTFIAEQAKGFRNAKHIAQWKMTMKVYAKRLQRLPLDGIETADVLAVLQP
VWTAKPETAKRTQGRIERILDAAKAQGLRKGENPARWRGHLDKLLSRQSKLSRGHHAALPYASVPAFVAKLRKSDAVSSL
ALEFLILTAARTGEVILARWNEIDAINAVWTVPAARMKAGREHRVPLSARALEILNAVVPVRTAPDGFIFPGAKEGKGLS
QMALAMMLRQCGEDDVTVHGFRSAFRDWAAEETDAPREVAEAALAHAVGDATERAYRRGDALAKRRVLMDAWSAFCT

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=377, Percent_Identity=32.3607427055703, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788974, Length=408, Percent_Identity=27.6960784313726, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788690, Length=395, Percent_Identity=26.3291139240506, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 43877; Mature: 43746

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKAKITTDKALAVLAGPGEIYSDSIKGTGLYLFVTKTGTRRWVFIYSRHGKRRELALG
CCCCCEECCCCEEEEEECCCHHHCCCCCCCEEEEEEEECCCEEEEEEEECCCCCEEEEEE
VVDGPKGISLKDARNQARAYQATLAQGGDPWDDARREKEQQIKAQTFGEFADTFIAEQAK
EECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFRNAKHIAQWKMTMKVYAKRLQRLPLDGIETADVLAVLQPVWTAKPETAKRTQGRIERI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LDAAKAQGLRKGENPARWRGHLDKLLSRQSKLSRGHHAALPYASVPAFVAKLRKSDAVSS
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LALEFLILTAARTGEVILARWNEIDAINAVWTVPAARMKAGREHRVPLSARALEILNAVV
HHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHH
PVRTAPDGFIFPGAKEGKGLSQMALAMMLRQCGEDDVTVHGFRSAFRDWAAEETDAPREV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCHHHH
AEAALAHAVGDATERAYRRGDALAKRRVLMDAWSAFCT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAKAKITTDKALAVLAGPGEIYSDSIKGTGLYLFVTKTGTRRWVFIYSRHGKRRELALG
CCCCEECCCCEEEEEECCCHHHCCCCCCCEEEEEEEECCCEEEEEEEECCCCCEEEEEE
VVDGPKGISLKDARNQARAYQATLAQGGDPWDDARREKEQQIKAQTFGEFADTFIAEQAK
EECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFRNAKHIAQWKMTMKVYAKRLQRLPLDGIETADVLAVLQPVWTAKPETAKRTQGRIERI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LDAAKAQGLRKGENPARWRGHLDKLLSRQSKLSRGHHAALPYASVPAFVAKLRKSDAVSS
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LALEFLILTAARTGEVILARWNEIDAINAVWTVPAARMKAGREHRVPLSARALEILNAVV
HHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHH
PVRTAPDGFIFPGAKEGKGLSQMALAMMLRQCGEDDVTVHGFRSAFRDWAAEETDAPREV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCHHHH
AEAALAHAVGDATERAYRRGDALAKRRVLMDAWSAFCT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]