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The map label for this gene is obgE

Identifier: 13473421

GI number: 13473421

Start: 3208541

End: 3209572

Strand: Reverse

Name: obgE

Synonym: mll4013

Alternate gene names: 13473421

Gene position: 3209572-3208541 (Counterclockwise)

Preceding gene: 13473423

Following gene: 13473420

Centisome position: 45.62

GC content: 65.41

Gene sequence:

>1032_bases
ATGAAATTTCTCGATCAAGCCAAGGTCTATGTCCGCTCCGGTGACGGGGGCGCCGGTTCGGTGTCGTTCCGGCGCGAGAA
ATTCATCGAGTTCGGCGGGCCGGATGGCGGCGATGGCGGGCGCGGCGGCGATGTCTGGCTGGAAGCGGTCGACGGGTTGA
ACACGCTGATCGACTACCGCTACCAGCAGCATTTCAAGGCCAAGACCGGCGTCCATGGCATGGGCCGCAACATGACCGGT
GCCAAGGGTGCCGACGTCACGCTGAAAGTGCCGGCCGGAACCCAGGTGTTCGAGGAAGACAATGAGACGCTGATCTGCGA
CCTCACCGTGGTCGGCCAGCGCTTCCTCCTCGCCAAGGGCGGCAATGGCGGCTTCGGCAACCAGCATTTCAAGACCTCGA
CCAACCAGGCGCCGCGCCGCGCCAATCCCGGTCTTCCCGGTGAAGAGCTCAACATCTGGCTGCGGTTGAAGCTGATCGCC
GATGCCGGGCTGGTCGGGCTGCCCAATGCCGGCAAGTCGACTTTCCTGGCGGCGGTCACCGCGGCCAAGCCGAAGATCGC
CGATTATCCGTTCACGACGCTGCATCCCGGCCTCGGCGTCGCGCGCATCGATGCGCGCGAATTCGTCATCGCCGACATTC
CGGGCCTCATCGAAGGCGCGCATGAGGGCGTCGGCATCGGCGACCGCTTCCTTGGCCATGTCGAGCGCACGCGCGTGCTG
CTGCATCTGGTCTCGGCGCAGGAGGAAAATCCGGGCAAGGCCTACAAGACCGTGCGCGCCGAGCTCGATGCCTATGGTAA
TGGATTGATCGAGAAGGTCGAGATACTGGCCCTTTCGCAAGTCGACACGCTCGATGCCGATGCACGCAGGAAGAAGGTGG
CCTCGCTGAAGCGCGCCGCCGGCCGCGCGCCGATGCTGCTGTCCGCCGTCACCGGCGAAGGTGTGGAGGCCGTTCTGCGG
GCGCTGATGACGGTGATTGCCGAGGCGCGCGCGGAGGCCGCGCCCGTGGTCGAGACGCGCTGGGAAAAGTAA

Upstream 100 bases:

>100_bases
ATTGTCACAAAACGGCCTCGCCCTTGACCGCGCCTTGGTTTAGAGCAAGGCCCAAGGTTTAGAGCAATGCCGCAAGGCCA
ATAAAAGAAACTGCAATCCC

Downstream 100 bases:

>100_bases
GACCATGCAGTCGCTGAAAAAATACCGGCGCATCACCGTCAAGATCGGCTCGGCGCTGCTCGTCGACCGCGCGAGCGGCT
TGAAGCGCGACTGGCTGGAC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKFLDQAKVYVRSGDGGAGSVSFRREKFIEFGGPDGGDGGRGGDVWLEAVDGLNTLIDYRYQQHFKAKTGVHGMGRNMTG
AKGADVTLKVPAGTQVFEEDNETLICDLTVVGQRFLLAKGGNGGFGNQHFKTSTNQAPRRANPGLPGEELNIWLRLKLIA
DAGLVGLPNAGKSTFLAAVTAAKPKIADYPFTTLHPGLGVARIDAREFVIADIPGLIEGAHEGVGIGDRFLGHVERTRVL
LHLVSAQEENPGKAYKTVRAELDAYGNGLIEKVEILALSQVDTLDADARRKKVASLKRAAGRAPMLLSAVTGEGVEAVLR
ALMTVIAEARAEAAPVVETRWEK

Sequences:

>Translated_343_residues
MKFLDQAKVYVRSGDGGAGSVSFRREKFIEFGGPDGGDGGRGGDVWLEAVDGLNTLIDYRYQQHFKAKTGVHGMGRNMTG
AKGADVTLKVPAGTQVFEEDNETLICDLTVVGQRFLLAKGGNGGFGNQHFKTSTNQAPRRANPGLPGEELNIWLRLKLIA
DAGLVGLPNAGKSTFLAAVTAAKPKIADYPFTTLHPGLGVARIDAREFVIADIPGLIEGAHEGVGIGDRFLGHVERTRVL
LHLVSAQEENPGKAYKTVRAELDAYGNGLIEKVEILALSQVDTLDADARRKKVASLKRAAGRAPMLLSAVTGEGVEAVLR
ALMTVIAEARAEAAPVVETRWEK
>Mature_343_residues
MKFLDQAKVYVRSGDGGAGSVSFRREKFIEFGGPDGGDGGRGGDVWLEAVDGLNTLIDYRYQQHFKAKTGVHGMGRNMTG
AKGADVTLKVPAGTQVFEEDNETLICDLTVVGQRFLLAKGGNGGFGNQHFKTSTNQAPRRANPGLPGEELNIWLRLKLIA
DAGLVGLPNAGKSTFLAAVTAAKPKIADYPFTTLHPGLGVARIDAREFVIADIPGLIEGAHEGVGIGDRFLGHVERTRVL
LHLVSAQEENPGKAYKTVRAELDAYGNGLIEKVEILALSQVDTLDADARRKKVASLKRAAGRAPMLLSAVTGEGVEAVLR
ALMTVIAEARAEAAPVVETRWEK

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=335, Percent_Identity=39.7014925373134, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI111955139, Length=356, Percent_Identity=35.3932584269663, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI111955063, Length=190, Percent_Identity=36.3157894736842, Blast_Score=105, Evalue=8e-23,
Organism=Escherichia coli, GI1789574, Length=344, Percent_Identity=50, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI1787454, Length=130, Percent_Identity=33.8461538461538, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=322, Percent_Identity=37.5776397515528, Blast_Score=147, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17552324, Length=320, Percent_Identity=29.0625, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321962, Length=167, Percent_Identity=38.9221556886228, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24585318, Length=292, Percent_Identity=36.986301369863, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI20129375, Length=325, Percent_Identity=35.6923076923077, Blast_Score=138, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_RHILO (Q98EZ3)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104988.1
- HSSP:   P44681
- ProteinModelPortal:   Q98EZ3
- SMR:   Q98EZ3
- GeneID:   1227649
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll4013
- NMPDR:   fig|266835.1.peg.3092
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- ProtClustDB:   PRK12299
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 36607; Mature: 36607

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDQAKVYVRSGDGGAGSVSFRREKFIEFGGPDGGDGGRGGDVWLEAVDGLNTLIDYR
CCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YQQHFKAKTGVHGMGRNMTGAKGADVTLKVPAGTQVFEEDNETLICDLTVVGQRFLLAKG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCEEEEEEEEECCEEEEEEC
GNGGFGNQHFKTSTNQAPRRANPGLPGEELNIWLRLKLIADAGLVGLPNAGKSTFLAAVT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCEEECCCCCCCCEEEEEE
AAKPKIADYPFTTLHPGLGVARIDAREFVIADIPGLIEGAHEGVGIGDRFLGHVERTRVL
CCCCCCCCCCCHHCCCCCCEEEECCCEEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHH
LHLVSAQEENPGKAYKTVRAELDAYGNGLIEKVEILALSQVDTLDADARRKKVASLKRAA
HHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHC
GRAPMLLSAVTGEGVEAVLRALMTVIAEARAEAAPVVETRWEK
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCC
>Mature Secondary Structure
MKFLDQAKVYVRSGDGGAGSVSFRREKFIEFGGPDGGDGGRGGDVWLEAVDGLNTLIDYR
CCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YQQHFKAKTGVHGMGRNMTGAKGADVTLKVPAGTQVFEEDNETLICDLTVVGQRFLLAKG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCEEEEEEEEECCEEEEEEC
GNGGFGNQHFKTSTNQAPRRANPGLPGEELNIWLRLKLIADAGLVGLPNAGKSTFLAAVT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCEEECCCCCCCCEEEEEE
AAKPKIADYPFTTLHPGLGVARIDAREFVIADIPGLIEGAHEGVGIGDRFLGHVERTRVL
CCCCCCCCCCCHHCCCCCCEEEECCCEEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHH
LHLVSAQEENPGKAYKTVRAELDAYGNGLIEKVEILALSQVDTLDADARRKKVASLKRAA
HHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHC
GRAPMLLSAVTGEGVEAVLRALMTVIAEARAEAAPVVETRWEK
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968