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The map label for this gene is ruvA

Identifier: 13473339

GI number: 13473339

Start: 3133447

End: 3134067

Strand: Reverse

Name: ruvA

Synonym: mll3898

Alternate gene names: 13473339

Gene position: 3134067-3133447 (Counterclockwise)

Preceding gene: 13473340

Following gene: 13473338

Centisome position: 44.54

GC content: 65.54

Gene sequence:

>621_bases
ATGATCGGCAAGCTCAAGGGCACGCTCGACGAGATCGACGAGGATCATTGCCTCGTCGACATTCATGGCGTCGGCTATGT
CGCCTATTGTTCGGCGCGCACACTTGCCGCGCTGCCTTCGCCCGGCGAGGCGGTGGTGCTGTTCATCGAGACCTATGTGC
GCGAGGATATGCTGCGCCTCTATGGTTTCCAGTCGGCCCTGGAGCGCGAATGGTTTCGGTTGCTGCTGAACAATGTGCCG
GGTGTCGGCGCCAAGGTGGCGCTGGCCATCCTGTCGACGCTGGCGCCGGCCGACCTCGCCAATGCGATCGCGCTGCGCGA
CATCGCCATGGTCAGCCGAGCCCCAGGCGTCGGCAAGAAGGTGGCTGAGCGCATCGTCACCGAATTGAAGAACAAGGCGC
CGGCCTATGCGGGCGCCGCCTCCGGCACCATCGGCCTGAAGCAGGAGCTCGGTGAAGGAGTGGCGCCCGCGCCGATCACC
GATGCGGTTTCGGCACTGGTCAATCTCGGCTATTCGCGCGACACCGCCGCCAATGCGGTGGCCGCGGCACTGAAGACGGC
GGGCGAGGACGCGGATGCCTCGAAGCTGATCCGCTTCGGGCTGAAGGAACTGGCGCGGTGA

Upstream 100 bases:

>100_bases
GACACGCGACGCCACGCGTTATCGCAGTTACTTTCCCGACCTCGAGATCATCTCTCCGGATATGCACCCATGAGGGCCCA
TCTTCCATGAAAGATCAGGC

Downstream 100 bases:

>100_bases
GGGCTCGCTTGTCCCTGCTCGTGCCATATGCCAGGAAGACAGCATGAGCCTGTCGCCCCGTCTCATTGCGCCGGAAAAAC
GCGGCGAGGATGCCGATCAG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MIGKLKGTLDEIDEDHCLVDIHGVGYVAYCSARTLAALPSPGEAVVLFIETYVREDMLRLYGFQSALEREWFRLLLNNVP
GVGAKVALAILSTLAPADLANAIALRDIAMVSRAPGVGKKVAERIVTELKNKAPAYAGAASGTIGLKQELGEGVAPAPIT
DAVSALVNLGYSRDTAANAVAAALKTAGEDADASKLIRFGLKELAR

Sequences:

>Translated_206_residues
MIGKLKGTLDEIDEDHCLVDIHGVGYVAYCSARTLAALPSPGEAVVLFIETYVREDMLRLYGFQSALEREWFRLLLNNVP
GVGAKVALAILSTLAPADLANAIALRDIAMVSRAPGVGKKVAERIVTELKNKAPAYAGAASGTIGLKQELGEGVAPAPIT
DAVSALVNLGYSRDTAANAVAAALKTAGEDADASKLIRFGLKELAR
>Mature_206_residues
MIGKLKGTLDEIDEDHCLVDIHGVGYVAYCSARTLAALPSPGEAVVLFIETYVREDMLRLYGFQSALEREWFRLLLNNVP
GVGAKVALAILSTLAPADLANAIALRDIAMVSRAPGVGKKVAERIVTELKNKAPAYAGAASGTIGLKQELGEGVAPAPIT
DAVSALVNLGYSRDTAANAVAAALKTAGEDADASKLIRFGLKELAR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=207, Percent_Identity=34.7826086956522, Blast_Score=110, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_RHILO (Q98F75)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104906.1
- ProteinModelPortal:   Q98F75
- SMR:   Q98F75
- GeneID:   1227567
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll3898
- NMPDR:   fig|266835.1.peg.3010
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- ProtClustDB:   PRK00116
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21588; Mature: 21588

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKLKGTLDEIDEDHCLVDIHGVGYVAYCSARTLAALPSPGEAVVLFIETYVREDMLRL
CCCCCCCCHHHCCCCCEEEEECCCCEEEHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHH
YGFQSALEREWFRLLLNNVPGVGAKVALAILSTLAPADLANAIALRDIAMVSRAPGVGKK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHH
VAERIVTELKNKAPAYAGAASGTIGLKQELGEGVAPAPITDAVSALVNLGYSRDTAANAV
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
AAALKTAGEDADASKLIRFGLKELAR
HHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGKLKGTLDEIDEDHCLVDIHGVGYVAYCSARTLAALPSPGEAVVLFIETYVREDMLRL
CCCCCCCCHHHCCCCCEEEEECCCCEEEHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHH
YGFQSALEREWFRLLLNNVPGVGAKVALAILSTLAPADLANAIALRDIAMVSRAPGVGKK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHH
VAERIVTELKNKAPAYAGAASGTIGLKQELGEGVAPAPITDAVSALVNLGYSRDTAANAV
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
AAALKTAGEDADASKLIRFGLKELAR
HHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968