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The map label for this gene is tbpA [H]

Identifier: 13473311

GI number: 13473311

Start: 3102965

End: 3103963

Strand: Reverse

Name: tbpA [H]

Synonym: mll3867

Alternate gene names: 13473311

Gene position: 3103963-3102965 (Counterclockwise)

Preceding gene: 13473312

Following gene: 13473310

Centisome position: 44.12

GC content: 63.06

Gene sequence:

>999_bases
ATGCGCACGCTTTTATACGCTCTTGTCTCGACGATGGTCGTGGCGCTGTCCGGGCCGGCCTTGGCCAAGGACAAGCTCAC
CGTCTACACCTATGAAAGCTTCACCGCCGACTGGGGTCCAGGCCCCGTGGTGAAGAAGGAATTCGAGGCCGAATGCGGCT
GCGACGTCGAGTTCGTCTCGGTCGCCGATGGCGTGGCCCTGCTCAACCGCGTCAAGCTCGAAGGGGCGTCGACCAAGGCC
GATATCGTGCTCGGCCTCGACACCAATCTCACCGCCGATGCCAAGGCTAGCGGGTTGTTTGCCCCGCATGGCGCGGTCTC
CGATGTCAACGTGCCGGGCGGCTGGAGCGACGACACTTTTGTTCCCTTCGACTACGGCTACTTCGCCGTCGTCTACGACA
CCGAAAAGCTGAAGACGCCGCCGAAGAGCCTGAAGGAACTGGTCGAAGGCAGTGCCGACGACAAGATCGTCATCCAGGAT
CCACGCACCTCGACGCCGGGCCTCGGCCTGCTGTTGTGGGTGAAGTCGGTCTACGGCGACAAGGCGCCGGAAGCCTGGGC
CAAGCTCAAGACGAAGGTGCTGACCGTGACGCCGGGCTGGAGCGAGGCCTATGGCCTGTTCACCAAGGGCGAGGCGCCGA
TGGTGCTGTCCTACACGACCTCGCCGGCCTACCACATGGTCGCCGAGAACACGCAGCGCTACCAGGCGGCTTCGTTCGAG
GAGGGCGAGTATCTGCAGATCGAGGTCGCGGGCATCACCACCACGGGGGCGAAGAATCCGCTGGCGGCGAAATTCATGGC
CTTCATGACCGGCCCAAAATTCCAGGATGCGATCCCCGAGACCAACTGGATGTTCCCGGCCGGCAAGACCGACAAGCCGC
TCAACCCGGCCTTCGACAAACTGGTCAAGCCGGCCAAGACCTTGCTGTTCAGCCCCGAAGAGGTCGCCGCCAACCGCAAG
GCTTGGGTGGATGAATGGCTGGCGGTGATGAGCAAATAG

Upstream 100 bases:

>100_bases
AACCCGCTGAACCTGATCCGGTTTGTACCGGCGGAGGGATTAGACGTTTCGGACAGTCCGGCGCCTCAATTCCTTTTCAA
TTCGAACGAAGGAGGCGCCG

Downstream 100 bases:

>100_bases
TTTGGCCGTATGATCGAAAGATGAGTGCTCTACGGCGCCCCCCTCTGTCCTGCCGGACATCTCCCCCACAAGGGGGGAGA
TCGAATGCTATCGGTGATTT

Product: thiamine transporter substrate binding subunit

Products: ADP; phosphate; thiamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MRTLLYALVSTMVVALSGPALAKDKLTVYTYESFTADWGPGPVVKKEFEAECGCDVEFVSVADGVALLNRVKLEGASTKA
DIVLGLDTNLTADAKASGLFAPHGAVSDVNVPGGWSDDTFVPFDYGYFAVVYDTEKLKTPPKSLKELVEGSADDKIVIQD
PRTSTPGLGLLLWVKSVYGDKAPEAWAKLKTKVLTVTPGWSEAYGLFTKGEAPMVLSYTTSPAYHMVAENTQRYQAASFE
EGEYLQIEVAGITTTGAKNPLAAKFMAFMTGPKFQDAIPETNWMFPAGKTDKPLNPAFDKLVKPAKTLLFSPEEVAANRK
AWVDEWLAVMSK

Sequences:

>Translated_332_residues
MRTLLYALVSTMVVALSGPALAKDKLTVYTYESFTADWGPGPVVKKEFEAECGCDVEFVSVADGVALLNRVKLEGASTKA
DIVLGLDTNLTADAKASGLFAPHGAVSDVNVPGGWSDDTFVPFDYGYFAVVYDTEKLKTPPKSLKELVEGSADDKIVIQD
PRTSTPGLGLLLWVKSVYGDKAPEAWAKLKTKVLTVTPGWSEAYGLFTKGEAPMVLSYTTSPAYHMVAENTQRYQAASFE
EGEYLQIEVAGITTTGAKNPLAAKFMAFMTGPKFQDAIPETNWMFPAGKTDKPLNPAFDKLVKPAKTLLFSPEEVAANRK
AWVDEWLAVMSK
>Mature_332_residues
MRTLLYALVSTMVVALSGPALAKDKLTVYTYESFTADWGPGPVVKKEFEAECGCDVEFVSVADGVALLNRVKLEGASTKA
DIVLGLDTNLTADAKASGLFAPHGAVSDVNVPGGWSDDTFVPFDYGYFAVVYDTEKLKTPPKSLKELVEGSADDKIVIQD
PRTSTPGLGLLLWVKSVYGDKAPEAWAKLKTKVLTVTPGWSEAYGLFTKGEAPMVLSYTTSPAYHMVAENTQRYQAASFE
EGEYLQIEVAGITTTGAKNPLAAKFMAFMTGPKFQDAIPETNWMFPAGKTDKPLNPAFDKLVKPAKTLLFSPEEVAANRK
AWVDEWLAVMSK

Specific function: Part of the ABC transporter complex thiBPQ involved in thiamine import [H]

COG id: COG4143

COG function: function code H; ABC-type thiamine transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

Organism=Escherichia coli, GI1786255, Length=317, Percent_Identity=60.2523659305994, Blast_Score=404, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059
- InterPro:   IPR005948
- InterPro:   IPR005967 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 35975; Mature: 35975

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLLYALVSTMVVALSGPALAKDKLTVYTYESFTADWGPGPVVKKEFEAECGCDVEFVS
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCCCCEEEEE
VADGVALLNRVKLEGASTKADIVLGLDTNLTADAKASGLFAPHGAVSDVNVPGGWSDDTF
HHHHHHHHHHHEECCCCCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCE
VPFDYGYFAVVYDTEKLKTPPKSLKELVEGSADDKIVIQDPRTSTPGLGLLLWVKSVYGD
EEECCCEEEEEEECHHHCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCC
KAPEAWAKLKTKVLTVTPGWSEAYGLFTKGEAPMVLSYTTSPAYHMVAENTQRYQAASFE
CCHHHHHHHEEEEEEECCCCHHHCCEEECCCCCEEEEECCCCCEEEHHCCCHHHHHCCCC
EGEYLQIEVAGITTTGAKNPLAAKFMAFMTGPKFQDAIPETNWMFPAGKTDKPLNPAFDK
CCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCHHHCCCCCCEECCCCCCCCCCCHHHHH
LVKPAKTLLFSPEEVAANRKAWVDEWLAVMSK
HHHHHHHHEECCHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRTLLYALVSTMVVALSGPALAKDKLTVYTYESFTADWGPGPVVKKEFEAECGCDVEFVS
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCCCCEEEEE
VADGVALLNRVKLEGASTKADIVLGLDTNLTADAKASGLFAPHGAVSDVNVPGGWSDDTF
HHHHHHHHHHHEECCCCCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCE
VPFDYGYFAVVYDTEKLKTPPKSLKELVEGSADDKIVIQDPRTSTPGLGLLLWVKSVYGD
EEECCCEEEEEEECHHHCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCC
KAPEAWAKLKTKVLTVTPGWSEAYGLFTKGEAPMVLSYTTSPAYHMVAENTQRYQAASFE
CCHHHHHHHEEEEEEECCCCHHHCCEEECCCCCEEEEECCCCCEEEHHCCCHHHHHCCCC
EGEYLQIEVAGITTTGAKNPLAAKFMAFMTGPKFQDAIPETNWMFPAGKTDKPLNPAFDK
CCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCHHHCCCCCCEECCCCCCCCCCCHHHHH
LVKPAKTLLFSPEEVAANRKAWVDEWLAVMSK
HHHHHHHHEECCHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; thiamine [Periplasm]; H2O [C]

Specific reaction: ATP + thiamine [Periplasm] + H2O = ADP + phosphate + thiamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA