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The map label for this gene is iorA [H]

Identifier: 13473288

GI number: 13473288

Start: 3077549

End: 3078010

Strand: Reverse

Name: iorA [H]

Synonym: mll3837

Alternate gene names: 13473288

Gene position: 3078010-3077549 (Counterclockwise)

Preceding gene: 13473290

Following gene: 13473287

Centisome position: 43.75

GC content: 66.45

Gene sequence:

>462_bases
ATGCGCCTTACCGTCGACGGGCAATCATTCGACATCGACGCCGATCCGGACATGCCGCTGCTGTGGGCGCTGCGCGATCT
CATAGGCAAGACCGGACCGAAGTTCGGCTGCGGCATTGCCGCCTGCGGCGCCTGCACCGTGCATGTCGATGGTCAACCGG
TGCGCTCCTGCTCGCTTCCGGTCGGCCAAGTCAGCGGCGCTGTCTCCACCATCGAAGGCATCGGCACAGCGGACAGGCTG
CATCCTGTGCAGCAGGCATGGCTGGAGGAACAGGTCGCGCAATGCGGCTATTGCCAGGCCGGCCAGATCATGAGCGCGGT
GGCGCTGCTGGACGAGGTCGCCGACCCGAGCGACGCCGACATCGACAACGCCACGGGCGGCAACCTCTGCCGCTGCGGCA
CCTATCCGAAGATCCGCTCGGCCATCAGGAAGGCTGCAGCGCTCAAGACGGCGGGGCTTTGA

Upstream 100 bases:

>100_bases
TCAATTGACAAAATGACGTAATTTGTCAATCTGTTTGAAGACGAAGCGACCCAAGGGGCTCTTCGCCCTCGGGCAGTGGA
CGACAACAAAGGGTATCCCC

Downstream 100 bases:

>100_bases
CAATGGCCAGTGTCGGAAAGATCGCCCGCCGCACGTTTCTGATCGGCGCGGCCGCTGTCGCGGGCGGCGTTGCCGTCGGC
TACTACTATTATCGCAAACC

Product: aldehyde dehydrogenase subunit III

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MRLTVDGQSFDIDADPDMPLLWALRDLIGKTGPKFGCGIAACGACTVHVDGQPVRSCSLPVGQVSGAVSTIEGIGTADRL
HPVQQAWLEEQVAQCGYCQAGQIMSAVALLDEVADPSDADIDNATGGNLCRCGTYPKIRSAIRKAAALKTAGL

Sequences:

>Translated_153_residues
MRLTVDGQSFDIDADPDMPLLWALRDLIGKTGPKFGCGIAACGACTVHVDGQPVRSCSLPVGQVSGAVSTIEGIGTADRL
HPVQQAWLEEQVAQCGYCQAGQIMSAVALLDEVADPSDADIDNATGGNLCRCGTYPKIRSAIRKAAALKTAGL
>Mature_153_residues
MRLTVDGQSFDIDADPDMPLLWALRDLIGKTGPKFGCGIAACGACTVHVDGQPVRSCSLPVGQVSGAVSTIEGIGTADRL
HPVQQAWLEEQVAQCGYCQAGQIMSAVALLDEVADPSDADIDNATGGNLCRCGTYPKIRSAIRKAAALKTAGL

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=146, Percent_Identity=39.7260273972603, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI71773480, Length=109, Percent_Identity=38.5321100917431, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=38.8888888888889, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1789232, Length=145, Percent_Identity=36.551724137931, Blast_Score=85, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17540638, Length=152, Percent_Identity=40.1315789473684, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=141, Percent_Identity=35.4609929078014, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32566215, Length=141, Percent_Identity=36.1702127659575, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17737937, Length=140, Percent_Identity=41.4285714285714, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24647201, Length=158, Percent_Identity=30.379746835443, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24647193, Length=161, Percent_Identity=31.055900621118, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=29.6296296296296, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647199, Length=138, Percent_Identity=31.1594202898551, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 15886; Mature: 15886

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTVDGQSFDIDADPDMPLLWALRDLIGKTGPKFGCGIAACGACTVHVDGQPVRSCSLP
CEEECCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEECCEEEEEECCCCCCCCCCC
VGQVSGAVSTIEGIGTADRLHPVQQAWLEEQVAQCGYCQAGQIMSAVALLDEVADPSDAD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCC
IDNATGGNLCRCGTYPKIRSAIRKAAALKTAGL
CCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLTVDGQSFDIDADPDMPLLWALRDLIGKTGPKFGCGIAACGACTVHVDGQPVRSCSLP
CEEECCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEECCEEEEEECCCCCCCCCCC
VGQVSGAVSTIEGIGTADRLHPVQQAWLEEQVAQCGYCQAGQIMSAVALLDEVADPSDAD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCC
IDNATGGNLCRCGTYPKIRSAIRKAAALKTAGL
CCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]