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The map label for this gene is iorB [H]

Identifier: 13473287

GI number: 13473287

Start: 3075273

End: 3077546

Strand: Reverse

Name: iorB [H]

Synonym: mll3836

Alternate gene names: 13473287

Gene position: 3077546-3075273 (Counterclockwise)

Preceding gene: 13473288

Following gene: 13473286

Centisome position: 43.74

GC content: 64.69

Gene sequence:

>2274_bases
ATGGCCAGTGTCGGAAAGATCGCCCGCCGCACGTTTCTGATCGGCGCGGCCGCTGTCGCGGGCGGCGTTGCCGTCGGCTA
CTACTATTATCGCAAACCGTTTGCGAACCCGCTCGAGGCCGATCTCGGCAAGGGCGAGGCGACCTTCAACCCCTATGTGA
AGATCGGCGCCGACAACACCATCACCATCGTCGCGCCGCGCGCCGAGATGGGACAAGGCATCTCGACGACGCTCGCCGTC
ATGGTCGCCGAAGAACTCGATGTCGGTCTCGATCAGGTCAAAGTCGAGCACGGCCCGGCCTCCTACGCCTATTACAACGC
GGCGATCCTCGAGGAGGGCGGTCCGTTCGCCTTCTTCGACGAGGGCATGACGGCGCAAGCGGTGCGCTCAGGTCTCGGTG
TGGTCGGCAAGTTCCTTGCTGTCCAGGCCACCGGCGGTTCGGCTTCAGCGCGTGATGGTTTCGACAAGATGCGCCAGGCG
GGCGCCGCAGCCCGGCATCTGCTGATCGCGGCCGCGGCGCAGAAACTCGGCGTTGCCGCCGCCGATCTGGAAACAGCCAA
CGGTTCGATCCTGCACAAGGCATCGGGCAAGTCGCTGACCTATGGCGCGGTTGCCGCGGCTGCCGCCACCATGGCGCCGT
CGGCCGAAGTCAGGCTCAAGGACAGAGTCGACTGGAAGCTGCTAGGAAAGCCGCAGAAGCGCATCGACATGCTGGCCAAG
GTCACCGGAGCGCCGATCTTCGGCATCGATGTCAGGCTGCCGGATATGCTCTACGGCACGGTGAAGATGAGCCCGCGCTT
CTGGGCCAAGCCAGTCAAGGCGGATCTCGCCAAAGCCGAGAAAATGCCCGGCGTGATCAAGATCGTGCCGCTCGAGACGA
ATTACGGCCATGGCTTCGGCATCATCGCGCAAAATACCTGGGCGGCCTTCAAGGCGGCCGACGCCATCGACGCCCAGTGG
GCGGAGCCCGAATATCCGCTCGGCAGCGCCGCCATATCAGACGTGCTGAAACAGGCGCTCGGCGCCAAGGGTTCGGCAAT
GCGCGACAATGGCGATGTCGATACCGCCTTCGCCGACGCGCCGCGCGAACGGATGGTCGAGGCGGACTATGCCGTGCCCT
ATCTGGCGCATGCGACCATGGAGCCGATGAATGCGACGGCGCGGTTCAAGGATGGCGCCTTGGACATCTGGTGCGGCAAC
CAGGCGCCGACCCTGCTGCGCCAGCTTTGCGCCAATGCGGTCGGCATCGGGCAGGACAAGGTCACTGTCCACACCACCTT
CATGGGCGGCGGTTTCGGCCGCCGTACCGAGATGGACTTCTCGCTTTGCGCCGCGTTGATGGCGAAGGAGACAGGCGGGC
GCCCAATCAAGGTGACCTGGACGCGCGAAGAGGACATGCGCCACGACGCCTACCGGCCGGCCGCGGTCGGCAAGTTTCAG
GCGCGGCTTGGCGACGACGGCATGCCGGTCGCCGTCGACATGAAGATCGCCTCGCCGTCGGTGATCGCCAGCACCTTGCG
CCGGCTGTTTCCCTCGATACCGCCGGTCGGTCCCGACAAGTCCATTGTCGATGGGGCCTATGACCAGCCCTACACCATTG
CGAACTATCGGGTGAGCGGCGTCGCGGCGCCCGTCTCGATTCCCGTCGGCTTCTGGCGCTCGGTCGGCAGTTCTATCAAC
GGCTTCTTCCATGAAGGGTTCATGGACGAGATTGCCACCGCCGGCAAAATCGATCCGATCGAGATGCGCAAGAGATTGAT
GGCCGCCTATCCCTCGGCGGTGAAGGTGGTGGAGAAAGTCGCGGCGATGGCGAAATGGGGCGAGGCGCTGCCTGCCGACA
AGGCCAAGGGCATGGCCTTCACGCTGTCTTTCGGAAGCTGGGTCGGCGAGATCGTCCAGGTGGCGGACACGCCGGCCGGC
ATCCGCATCGAGAAGGTATGGATCGCCGCCGATGTCGGCACCGCGCTCGATCCGGGCATCATCGAGGCGCAGCTGATCTC
CGCCGCCATCTATGGCCTGTCGGCGGCAATGGGACAGCAGATCACCTTCGCCGACGGCATGGTCGAACAGTCGAACTTCC
ACGATTTCGACGCCATGCGGATCTTCCAGTGCCCGGTCTTCGAAGTCGCCATCCTGGAGAATTTCCACAAGATGGGTGGC
GTCGGCGAGGTTGGCACACCGCCGGCGGCGCCGGCGCTGGCTAATGCCATCTTCGCGCTTACCGGCAAGCGCATCCGCAC
ACTGCCGCTGTCGACAACGGTGGCCTTCGCATGA

Upstream 100 bases:

>100_bases
ACAACGCCACGGGCGGCAACCTCTGCCGCTGCGGCACCTATCCGAAGATCCGCTCGGCCATCAGGAAGGCTGCAGCGCTC
AAGACGGCGGGGCTTTGACA

Downstream 100 bases:

>100_bases
AAAAGCTTCTCATCATGCTGACGCCTGCTGCCATCTTGTTTTCGGCGGCGCCTTTCGCAACCGCTCAGGAGAGCCAGACA
TCATCGAGCCCGACGGTAGA

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 757; Mature: 756

Protein sequence:

>757_residues
MASVGKIARRTFLIGAAAVAGGVAVGYYYYRKPFANPLEADLGKGEATFNPYVKIGADNTITIVAPRAEMGQGISTTLAV
MVAEELDVGLDQVKVEHGPASYAYYNAAILEEGGPFAFFDEGMTAQAVRSGLGVVGKFLAVQATGGSASARDGFDKMRQA
GAAARHLLIAAAAQKLGVAAADLETANGSILHKASGKSLTYGAVAAAAATMAPSAEVRLKDRVDWKLLGKPQKRIDMLAK
VTGAPIFGIDVRLPDMLYGTVKMSPRFWAKPVKADLAKAEKMPGVIKIVPLETNYGHGFGIIAQNTWAAFKAADAIDAQW
AEPEYPLGSAAISDVLKQALGAKGSAMRDNGDVDTAFADAPRERMVEADYAVPYLAHATMEPMNATARFKDGALDIWCGN
QAPTLLRQLCANAVGIGQDKVTVHTTFMGGGFGRRTEMDFSLCAALMAKETGGRPIKVTWTREEDMRHDAYRPAAVGKFQ
ARLGDDGMPVAVDMKIASPSVIASTLRRLFPSIPPVGPDKSIVDGAYDQPYTIANYRVSGVAAPVSIPVGFWRSVGSSIN
GFFHEGFMDEIATAGKIDPIEMRKRLMAAYPSAVKVVEKVAAMAKWGEALPADKAKGMAFTLSFGSWVGEIVQVADTPAG
IRIEKVWIAADVGTALDPGIIEAQLISAAIYGLSAAMGQQITFADGMVEQSNFHDFDAMRIFQCPVFEVAILENFHKMGG
VGEVGTPPAAPALANAIFALTGKRIRTLPLSTTVAFA

Sequences:

>Translated_757_residues
MASVGKIARRTFLIGAAAVAGGVAVGYYYYRKPFANPLEADLGKGEATFNPYVKIGADNTITIVAPRAEMGQGISTTLAV
MVAEELDVGLDQVKVEHGPASYAYYNAAILEEGGPFAFFDEGMTAQAVRSGLGVVGKFLAVQATGGSASARDGFDKMRQA
GAAARHLLIAAAAQKLGVAAADLETANGSILHKASGKSLTYGAVAAAAATMAPSAEVRLKDRVDWKLLGKPQKRIDMLAK
VTGAPIFGIDVRLPDMLYGTVKMSPRFWAKPVKADLAKAEKMPGVIKIVPLETNYGHGFGIIAQNTWAAFKAADAIDAQW
AEPEYPLGSAAISDVLKQALGAKGSAMRDNGDVDTAFADAPRERMVEADYAVPYLAHATMEPMNATARFKDGALDIWCGN
QAPTLLRQLCANAVGIGQDKVTVHTTFMGGGFGRRTEMDFSLCAALMAKETGGRPIKVTWTREEDMRHDAYRPAAVGKFQ
ARLGDDGMPVAVDMKIASPSVIASTLRRLFPSIPPVGPDKSIVDGAYDQPYTIANYRVSGVAAPVSIPVGFWRSVGSSIN
GFFHEGFMDEIATAGKIDPIEMRKRLMAAYPSAVKVVEKVAAMAKWGEALPADKAKGMAFTLSFGSWVGEIVQVADTPAG
IRIEKVWIAADVGTALDPGIIEAQLISAAIYGLSAAMGQQITFADGMVEQSNFHDFDAMRIFQCPVFEVAILENFHKMGG
VGEVGTPPAAPALANAIFALTGKRIRTLPLSTTVAFA
>Mature_756_residues
ASVGKIARRTFLIGAAAVAGGVAVGYYYYRKPFANPLEADLGKGEATFNPYVKIGADNTITIVAPRAEMGQGISTTLAVM
VAEELDVGLDQVKVEHGPASYAYYNAAILEEGGPFAFFDEGMTAQAVRSGLGVVGKFLAVQATGGSASARDGFDKMRQAG
AAARHLLIAAAAQKLGVAAADLETANGSILHKASGKSLTYGAVAAAAATMAPSAEVRLKDRVDWKLLGKPQKRIDMLAKV
TGAPIFGIDVRLPDMLYGTVKMSPRFWAKPVKADLAKAEKMPGVIKIVPLETNYGHGFGIIAQNTWAAFKAADAIDAQWA
EPEYPLGSAAISDVLKQALGAKGSAMRDNGDVDTAFADAPRERMVEADYAVPYLAHATMEPMNATARFKDGALDIWCGNQ
APTLLRQLCANAVGIGQDKVTVHTTFMGGGFGRRTEMDFSLCAALMAKETGGRPIKVTWTREEDMRHDAYRPAAVGKFQA
RLGDDGMPVAVDMKIASPSVIASTLRRLFPSIPPVGPDKSIVDGAYDQPYTIANYRVSGVAAPVSIPVGFWRSVGSSING
FFHEGFMDEIATAGKIDPIEMRKRLMAAYPSAVKVVEKVAAMAKWGEALPADKAKGMAFTLSFGSWVGEIVQVADTPAGI
RIEKVWIAADVGTALDPGIIEAQLISAAIYGLSAAMGQQITFADGMVEQSNFHDFDAMRIFQCPVFEVAILENFHKMGGV
GEVGTPPAAPALANAIFALTGKRIRTLPLSTTVAFA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789230, Length=402, Percent_Identity=26.1194029850746, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 80101; Mature: 79970

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVGKIARRTFLIGAAAVAGGVAVGYYYYRKPFANPLEADLGKGEATFNPYVKIGADNT
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEECCCCE
ITIVAPRAEMGQGISTTLAVMVAEELDVGLDQVKVEHGPASYAYYNAAILEEGGPFAFFD
EEEEECHHHHCCCHHHHHHHHHHHHHCCCHHHEEEECCCCCEEEEEEEEEECCCCEEEEC
EGMTAQAVRSGLGVVGKFLAVQATGGSASARDGFDKMRQAGAAARHLLIAAAAQKLGVAA
CCCCHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
ADLETANGSILHKASGKSLTYGAVAAAAATMAPSAEVRLKDRVDWKLLGKPQKRIDMLAK
ECCCCCCCCEEEECCCCCEEHHHHHHHHHHCCCCCCEEEECCCCEEECCCCHHHHHHHHH
VTGAPIFGIDVRLPDMLYGTVKMSPRFWAKPVKADLAKAEKMPGVIKIVPLETNYGHGFG
HCCCCEEEEEEECCCCEEEEEEECCHHHCCCHHHHHHHHHCCCCEEEEEEEECCCCCCEE
IIAQNTWAAFKAADAIDAQWAEPEYPLGSAAISDVLKQALGAKGSAMRDNGDVDTAFADA
EEECCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCC
PRERMVEADYAVPYLAHATMEPMNATARFKDGALDIWCGNQAPTLLRQLCANAVGIGQDK
CHHHHHHHCCCCHHHHHHHCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCC
VTVHTTFMGGGFGRRTEMDFSLCAALMAKETGGRPIKVTWTREEDMRHDAYRPAAVGKFQ
EEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCHHHHHH
ARLGDDGMPVAVDMKIASPSVIASTLRRLFPSIPPVGPDKSIVDGAYDQPYTIANYRVSG
HHCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEC
VAAPVSIPVGFWRSVGSSINGFFHEGFMDEIATAGKIDPIEMRKRLMAAYPSAVKVVEKV
EECCEECCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHH
AAMAKWGEALPADKAKGMAFTLSFGSWVGEIVQVADTPAGIRIEKVWIAADVGTALDPGI
HHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCH
IEAQLISAAIYGLSAAMGQQITFADGMVEQSNFHDFDAMRIFQCPVFEVAILENFHKMGG
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCC
VGEVGTPPAAPALANAIFALTGKRIRTLPLSTTVAFA
CCCCCCCCCCHHHHHHHHHHCCCEEEEEECCEEEECC
>Mature Secondary Structure 
ASVGKIARRTFLIGAAAVAGGVAVGYYYYRKPFANPLEADLGKGEATFNPYVKIGADNT
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEECCCCE
ITIVAPRAEMGQGISTTLAVMVAEELDVGLDQVKVEHGPASYAYYNAAILEEGGPFAFFD
EEEEECHHHHCCCHHHHHHHHHHHHHCCCHHHEEEECCCCCEEEEEEEEEECCCCEEEEC
EGMTAQAVRSGLGVVGKFLAVQATGGSASARDGFDKMRQAGAAARHLLIAAAAQKLGVAA
CCCCHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
ADLETANGSILHKASGKSLTYGAVAAAAATMAPSAEVRLKDRVDWKLLGKPQKRIDMLAK
ECCCCCCCCEEEECCCCCEEHHHHHHHHHHCCCCCCEEEECCCCEEECCCCHHHHHHHHH
VTGAPIFGIDVRLPDMLYGTVKMSPRFWAKPVKADLAKAEKMPGVIKIVPLETNYGHGFG
HCCCCEEEEEEECCCCEEEEEEECCHHHCCCHHHHHHHHHCCCCEEEEEEEECCCCCCEE
IIAQNTWAAFKAADAIDAQWAEPEYPLGSAAISDVLKQALGAKGSAMRDNGDVDTAFADA
EEECCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCC
PRERMVEADYAVPYLAHATMEPMNATARFKDGALDIWCGNQAPTLLRQLCANAVGIGQDK
CHHHHHHHCCCCHHHHHHHCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCC
VTVHTTFMGGGFGRRTEMDFSLCAALMAKETGGRPIKVTWTREEDMRHDAYRPAAVGKFQ
EEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCHHHHHH
ARLGDDGMPVAVDMKIASPSVIASTLRRLFPSIPPVGPDKSIVDGAYDQPYTIANYRVSG
HHCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEC
VAAPVSIPVGFWRSVGSSINGFFHEGFMDEIATAGKIDPIEMRKRLMAAYPSAVKVVEKV
EECCEECCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHH
AAMAKWGEALPADKAKGMAFTLSFGSWVGEIVQVADTPAGIRIEKVWIAADVGTALDPGI
HHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCH
IEAQLISAAIYGLSAAMGQQITFADGMVEQSNFHDFDAMRIFQCPVFEVAILENFHKMGG
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCC
VGEVGTPPAAPALANAIFALTGKRIRTLPLSTTVAFA
CCCCCCCCCCHHHHHHHHHHCCCEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]