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The map label for this gene is qorA [H]

Identifier: 13473234

GI number: 13473234

Start: 3031306

End: 3032286

Strand: Reverse

Name: qorA [H]

Synonym: mll3767

Alternate gene names: 13473234

Gene position: 3032286-3031306 (Counterclockwise)

Preceding gene: 13473238

Following gene: 13473233

Centisome position: 43.1

GC content: 65.95

Gene sequence:

>981_bases
ATGACGGCAATCGCTATCTCGGTACCGGGTGGCCCACGGGTGCTGAAACCGGAAACGCGCGATGTGCCGCAGCCCGGCCC
AGGTGAGATCCTGATCAAGGTGCATGCCGCCGGCGTCAACCGGCCCGACGTGCAGCAGCGCAAGGGCGCCTATCCGCCGC
CGCCCGGCGCATCGGACCTGCCGGGCCTCGAAGTGTCGGGCGAAGTGGCTGCCCTTGGCGACGAGATATCGCGCTGGCGC
ATCGGCGACCGGGTGTGCGCGCTGACTCCCGGCGGCGGCTATGCCGAATATGTCAAGGTTCACTCCGGCAGCGTGCTGCC
GCTGCCCGCCGGTTTCACCCACACCGAAGCAGCGGCGGTGCCGGAAAACTATTTCACCGTCTGGCACAATGTGTTCGAAC
GCGGCGCCCTGAAGAAAGGCGAGACGCTGCTGGTGCATGGCGGCTCGTCCGGCATCGGCACGACGGCGATCCAGCTGGCT
TCGGCCTTCGGCGCCTATGTCATCACCACCGCCGGGTCCAAGGAGAAATGCGACGCCTGCCTGAAGCTCGGCGCCGACCG
GGCGATCAATTACCGCGAGGAAGATTTCGTCACGGCGGTCAAGGAGGCGACGGATGGCAAGGGCGCCACTGTCATCCTCG
ACATGGTCGGCGGCGACTATGTCCAGCGCAACTACGAGGCGGCAGCCGTCGAGGGCCGCATTGTCCAGATCGCCGTGCAG
GCTGGTGCTGTCGCCAGCGCCGATTTTTCGAAGATCATGGTCAAGCGGCTGACCCACACCGGTTCGACGCTCAGGCCGCG
CACTGTCGAGTTCAAGGCGGCGATCGCAGCGGCGCTGGAGGCACAGGTGTGGCCGCTGCTCGGCACACGCAAGGTCGCAC
CTGTCATGGACATGATCTACCCGCTTACCGATGCCTGGCGTGCGCATGAGCGGATGGAGGAGGGCGAGCATATTGGCAAG
ATCGTGCTCGACGTCGGCTAG

Upstream 100 bases:

>100_bases
AGCATACATAGGGCAAGGGCGTCGATGCAAACAGCCGGTAAGAATGCGGCGAGGAAAGACGGGAAACTTCATGGCGAGCG
GACAAAAAATTCCGGCGAGG

Downstream 100 bases:

>100_bases
GACGGCGATATTCAGGTGAGCCCGGCCTGCGAATGGCGGCTTCCTGCGCTTCCGGTGCTCACGTACCCTAGTACGCTCCG
CTCCGGTTCTCGGAAACCAC

Product: NADPH quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTAIAISVPGGPRVLKPETRDVPQPGPGEILIKVHAAGVNRPDVQQRKGAYPPPPGASDLPGLEVSGEVAALGDEISRWR
IGDRVCALTPGGGYAEYVKVHSGSVLPLPAGFTHTEAAAVPENYFTVWHNVFERGALKKGETLLVHGGSSGIGTTAIQLA
SAFGAYVITTAGSKEKCDACLKLGADRAINYREEDFVTAVKEATDGKGATVILDMVGGDYVQRNYEAAAVEGRIVQIAVQ
AGAVASADFSKIMVKRLTHTGSTLRPRTVEFKAAIAAALEAQVWPLLGTRKVAPVMDMIYPLTDAWRAHERMEEGEHIGK
IVLDVG

Sequences:

>Translated_326_residues
MTAIAISVPGGPRVLKPETRDVPQPGPGEILIKVHAAGVNRPDVQQRKGAYPPPPGASDLPGLEVSGEVAALGDEISRWR
IGDRVCALTPGGGYAEYVKVHSGSVLPLPAGFTHTEAAAVPENYFTVWHNVFERGALKKGETLLVHGGSSGIGTTAIQLA
SAFGAYVITTAGSKEKCDACLKLGADRAINYREEDFVTAVKEATDGKGATVILDMVGGDYVQRNYEAAAVEGRIVQIAVQ
AGAVASADFSKIMVKRLTHTGSTLRPRTVEFKAAIAAALEAQVWPLLGTRKVAPVMDMIYPLTDAWRAHERMEEGEHIGK
IVLDVG
>Mature_325_residues
TAIAISVPGGPRVLKPETRDVPQPGPGEILIKVHAAGVNRPDVQQRKGAYPPPPGASDLPGLEVSGEVAALGDEISRWRI
GDRVCALTPGGGYAEYVKVHSGSVLPLPAGFTHTEAAAVPENYFTVWHNVFERGALKKGETLLVHGGSSGIGTTAIQLAS
AFGAYVITTAGSKEKCDACLKLGADRAINYREEDFVTAVKEATDGKGATVILDMVGGDYVQRNYEAAAVEGRIVQIAVQA
GAVASADFSKIMVKRLTHTGSTLRPRTVEFKAAIAAALEAQVWPLLGTRKVAPVMDMIYPLTDAWRAHERMEEGEHIGKI
VLDVG

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=42.4242424242424, Blast_Score=260, Evalue=1e-69,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=42.4242424242424, Blast_Score=260, Evalue=1e-69,
Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=33.434650455927, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=33.434650455927, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI194239676, Length=329, Percent_Identity=31.306990881459, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI24308257, Length=344, Percent_Identity=28.7790697674419, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI18379349, Length=330, Percent_Identity=26.6666666666667, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI41872631, Length=314, Percent_Identity=30.8917197452229, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI28557745, Length=328, Percent_Identity=30.1829268292683, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI47519420, Length=342, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI197927207, Length=198, Percent_Identity=29.7979797979798, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1790485, Length=314, Percent_Identity=33.4394904458599, Blast_Score=138, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17507255, Length=316, Percent_Identity=26.8987341772152, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI212642053, Length=306, Percent_Identity=28.4313725490196, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71987554, Length=356, Percent_Identity=24.438202247191, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536829, Length=200, Percent_Identity=26.5, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=328, Percent_Identity=28.9634146341463, Blast_Score=109, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6323961, Length=340, Percent_Identity=26.4705882352941, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=340, Percent_Identity=27.6470588235294, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=340, Percent_Identity=26.4705882352941, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI221330659, Length=297, Percent_Identity=29.6296296296296, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19920632, Length=297, Percent_Identity=29.6296296296296, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24581345, Length=297, Percent_Identity=27.9461279461279, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34485; Mature: 34354

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIAISVPGGPRVLKPETRDVPQPGPGEILIKVHAAGVNRPDVQQRKGAYPPPPGASDL
CEEEEEECCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCCCCCCC
PGLEVSGEVAALGDEISRWRIGDRVCALTPGGGYAEYVKVHSGSVLPLPAGFTHTEAAAV
CCCCCCCCHHHHHHHHHHEECCCEEEEECCCCCCEEEEEEECCCEEECCCCCCCCHHHHC
PENYFTVWHNVFERGALKKGETLLVHGGSSGIGTTAIQLASAFGAYVITTAGSKEKCDAC
CHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHH
LKLGADRAINYREEDFVTAVKEATDGKGATVILDMVGGDYVQRNYEAAAVEGRIVQIAVQ
HHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHCCCCEEEECCEEEEEEEE
AGAVASADFSKIMVKRLTHTGSTLRPRTVEFKAAIAAALEAQVWPLLGTRKVAPVMDMIY
CCCCCCCHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
PLTDAWRAHERMEEGEHIGKIVLDVG
HHHHHHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure 
TAIAISVPGGPRVLKPETRDVPQPGPGEILIKVHAAGVNRPDVQQRKGAYPPPPGASDL
EEEEEECCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCCCCCCC
PGLEVSGEVAALGDEISRWRIGDRVCALTPGGGYAEYVKVHSGSVLPLPAGFTHTEAAAV
CCCCCCCCHHHHHHHHHHEECCCEEEEECCCCCCEEEEEEECCCEEECCCCCCCCHHHHC
PENYFTVWHNVFERGALKKGETLLVHGGSSGIGTTAIQLASAFGAYVITTAGSKEKCDAC
CHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHH
LKLGADRAINYREEDFVTAVKEATDGKGATVILDMVGGDYVQRNYEAAAVEGRIVQIAVQ
HHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHCCCCEEEECCEEEEEEEE
AGAVASADFSKIMVKRLTHTGSTLRPRTVEFKAAIAAALEAQVWPLLGTRKVAPVMDMIY
CCCCCCCHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
PLTDAWRAHERMEEGEHIGKIVLDVG
HHHHHHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]