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The map label for this gene is cbbT [H]

Identifier: 13473220

GI number: 13473220

Start: 3016369

End: 3018420

Strand: Direct

Name: cbbT [H]

Synonym: mlr3749

Alternate gene names: 13473220

Gene position: 3016369-3018420 (Clockwise)

Preceding gene: 13473215

Following gene: 13473221

Centisome position: 42.87

GC content: 65.25

Gene sequence:

>2052_bases
GTGTCGCGCACCTTTTCAAGGGCGCTCCCAAGCCCCCAAACCCCCACCTTTGGAGGAACCATGACGTCGCGTGAACAACA
TGATCGGATGGCCAATGCGATCCGCTTTCTCTCCATGGATGCCGTCGAGAAGGCCCAGTCCGGCCATCCCGGCCTGCCCA
TGGGCTGCGCCGACATTGCAACGGTGCTGTTCACCCGCTTCCTGAAATACGATCCCAAAGCCCCGCACTGGCCCGACCGC
GACCGCTTCATCCTGTCGGCTGGCCATGGCTCGATGCTGCTCTATTCGCTGCTGCATCTGACCGGCTACGAAGACATGAC
CATCGACCAGATCAAGCACTTCCGCCAGCTCGGCTCCAAGACCGCCGGCCATCCCGAATACGGCCACGCCACCGGCATCG
AGACGACGACCGGCCCGCTCGGCCAGGGCCTCGCCAATTCGGTTGGCTTCGCGCTCGGCGAGCGCATCATGAACGCCGCT
TTCGGCAACGACCTCGTCAGCCACTACACCTATGTGCTGGCCGGCGACGGCTGCCTGATGGAGGGCGTTTCCCAGGAAGC
CATTGCGCTGGCCGGGCATCTCAAGCTCAACAAGCTGATCGTCTTCTGGGACAACAACAACATCTCGATCGACGGCCCGG
TCTCGCTGGCCGACAACACCGACCAGGTTGCCCGTTTCCAGGCCTCCGGCTGGAACGCCAGCCATATCGACGGCACCGAT
CCGGAAGCCATCGCCTACGCCATCGAAGCCGCCCGCCATTCCGACAAGCCGACGATGATCGCCTGCAAGACGACCATCGG
CTTCGGCGCGCCGACCAAGGCCGGCACCAACAAGGCACACGGTTCGCCGCTCGGCGCCGACGAGATCGCCGGTGCGCGCA
AGTTCTTCAACTGGGAGTCGCCGCCCTTCGAGATTCCGGCCGACATCCTCGATGCCTGGCGCACCGCCGGCAAGGCCGGA
GCCAAGCCGCGCGCCGACTGGGAAGGCCGTCTCGCCAAGGCCGAGCCGAAGCTGAAGGCCGAGTTCGAGCGCCGGCTCGC
CGGCAAGCTGCCGTCCAATTTCGACGCCGTCATCGCCGACTACAAGAAGAAGCTCTCGGCCGACAAGCCGAAGGTCGCCA
CCCGCAAATCGTCGGAAATGGCGCTTGAGGTCATCAACGGCGCCGTTCCGGAAACTATCGGCGGCTCCGCCGACCTGACC
GGCTCCAACAACACCAAGACCAGCCAGACCAAGAACATCACGCCGGACGATTACGGCCAGCGCTATGTCCACTACGGCAT
CCGCGAGCACGGCATGGCGGCGGCCATCAACGGCCTGACGCTGCATGGCGGCCTCATCGCCTATGGCGGCACCTTCATGT
GCTTCTCCGACTATGCTCGCCCGTCGATGCGGCTTTCCTCGCTGATGGGCATCCGCTCGATCTTCGTCATGACCCATGAT
TCCATCGGTCTGGGCGAGGACGGCCCGACCCACCAGCCGGTCGAGCATCTGGCAGCGCTGCGCGCCATTCCCAACCACAA
TGTCTTCCGCCCGGCCGACGCCGTGGAAACCGCGGAATGCTGGCAGATCGCGCTCGAATCCGAAAAGACGCCGTCGACGC
TGGCGCTGACCCGCCAGAACCTGCCGACGGTGCGCATCGAGCACTCGGCCAAGAACCTGAGCAGCCAGGGCGCTTACGAA
CTGGCCGCGGCCAGCGGCGAGGCGGCAGTGACGATCTTCGCCACCGGCTCCGAGGTCGAGATCGCACTCGGCGCCCGCGA
CCTGCTCGAGAAGCATGGCCACCCGACCCGCGTCGTGTCGGTGCCTTGCTTCGAGCTGTTCGACAAGCAGAGCGACGACT
ACCGCAAGAAGACGATCGGCAACGCGCCTATCAAGATGGCGATCGAGGCCGGCATCCGCCAGGGTTGGGACCATCTCATC
GGCTCGGACGGCATCTTCGTCGGCATGACCGGCTTCGGCGCCTCGGGCACGATCGAGCAGCTCTACCCGCATTTCGGCAT
CACCGCCGAGGCGGCGGCCAAGGCGGCGGAAGCCCGCCTGCACGCCAAGTAA

Upstream 100 bases:

>100_bases
CGCGACTGTCCCCCGCTAACGCTAATGTAGGGCCGCCGCCAGCATCACAAGACCGGCAAATCTGCGCCCGATTTGTTGAC
TAAAAGCCCGCGCCTGCTAT

Downstream 100 bases:

>100_bases
GGCTCAGCATGCCGCCCAAAACTGTGTCGCGGTTTGGGATAATGGCATGCACAAAACAGAAATGCCCCCGGCGAAACCGC
GCAAAGCGATTTCGCCGGAC

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 683; Mature: 682

Protein sequence:

>683_residues
MSRTFSRALPSPQTPTFGGTMTSREQHDRMANAIRFLSMDAVEKAQSGHPGLPMGCADIATVLFTRFLKYDPKAPHWPDR
DRFILSAGHGSMLLYSLLHLTGYEDMTIDQIKHFRQLGSKTAGHPEYGHATGIETTTGPLGQGLANSVGFALGERIMNAA
FGNDLVSHYTYVLAGDGCLMEGVSQEAIALAGHLKLNKLIVFWDNNNISIDGPVSLADNTDQVARFQASGWNASHIDGTD
PEAIAYAIEAARHSDKPTMIACKTTIGFGAPTKAGTNKAHGSPLGADEIAGARKFFNWESPPFEIPADILDAWRTAGKAG
AKPRADWEGRLAKAEPKLKAEFERRLAGKLPSNFDAVIADYKKKLSADKPKVATRKSSEMALEVINGAVPETIGGSADLT
GSNNTKTSQTKNITPDDYGQRYVHYGIREHGMAAAINGLTLHGGLIAYGGTFMCFSDYARPSMRLSSLMGIRSIFVMTHD
SIGLGEDGPTHQPVEHLAALRAIPNHNVFRPADAVETAECWQIALESEKTPSTLALTRQNLPTVRIEHSAKNLSSQGAYE
LAAASGEAAVTIFATGSEVEIALGARDLLEKHGHPTRVVSVPCFELFDKQSDDYRKKTIGNAPIKMAIEAGIRQGWDHLI
GSDGIFVGMTGFGASGTIEQLYPHFGITAEAAAKAAEARLHAK

Sequences:

>Translated_683_residues
MSRTFSRALPSPQTPTFGGTMTSREQHDRMANAIRFLSMDAVEKAQSGHPGLPMGCADIATVLFTRFLKYDPKAPHWPDR
DRFILSAGHGSMLLYSLLHLTGYEDMTIDQIKHFRQLGSKTAGHPEYGHATGIETTTGPLGQGLANSVGFALGERIMNAA
FGNDLVSHYTYVLAGDGCLMEGVSQEAIALAGHLKLNKLIVFWDNNNISIDGPVSLADNTDQVARFQASGWNASHIDGTD
PEAIAYAIEAARHSDKPTMIACKTTIGFGAPTKAGTNKAHGSPLGADEIAGARKFFNWESPPFEIPADILDAWRTAGKAG
AKPRADWEGRLAKAEPKLKAEFERRLAGKLPSNFDAVIADYKKKLSADKPKVATRKSSEMALEVINGAVPETIGGSADLT
GSNNTKTSQTKNITPDDYGQRYVHYGIREHGMAAAINGLTLHGGLIAYGGTFMCFSDYARPSMRLSSLMGIRSIFVMTHD
SIGLGEDGPTHQPVEHLAALRAIPNHNVFRPADAVETAECWQIALESEKTPSTLALTRQNLPTVRIEHSAKNLSSQGAYE
LAAASGEAAVTIFATGSEVEIALGARDLLEKHGHPTRVVSVPCFELFDKQSDDYRKKTIGNAPIKMAIEAGIRQGWDHLI
GSDGIFVGMTGFGASGTIEQLYPHFGITAEAAAKAAEARLHAK
>Mature_682_residues
SRTFSRALPSPQTPTFGGTMTSREQHDRMANAIRFLSMDAVEKAQSGHPGLPMGCADIATVLFTRFLKYDPKAPHWPDRD
RFILSAGHGSMLLYSLLHLTGYEDMTIDQIKHFRQLGSKTAGHPEYGHATGIETTTGPLGQGLANSVGFALGERIMNAAF
GNDLVSHYTYVLAGDGCLMEGVSQEAIALAGHLKLNKLIVFWDNNNISIDGPVSLADNTDQVARFQASGWNASHIDGTDP
EAIAYAIEAARHSDKPTMIACKTTIGFGAPTKAGTNKAHGSPLGADEIAGARKFFNWESPPFEIPADILDAWRTAGKAGA
KPRADWEGRLAKAEPKLKAEFERRLAGKLPSNFDAVIADYKKKLSADKPKVATRKSSEMALEVINGAVPETIGGSADLTG
SNNTKTSQTKNITPDDYGQRYVHYGIREHGMAAAINGLTLHGGLIAYGGTFMCFSDYARPSMRLSSLMGIRSIFVMTHDS
IGLGEDGPTHQPVEHLAALRAIPNHNVFRPADAVETAECWQIALESEKTPSTLALTRQNLPTVRIEHSAKNLSSQGAYEL
AAASGEAAVTIFATGSEVEIALGARDLLEKHGHPTRVVSVPCFELFDKQSDDYRKKTIGNAPIKMAIEAGIRQGWDHLIG
SDGIFVGMTGFGASGTIEQLYPHFGITAEAAAKAAEARLHAK

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=653, Percent_Identity=26.7993874425727, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI4507521, Length=653, Percent_Identity=26.7993874425727, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI133778974, Length=661, Percent_Identity=25.8698940998487, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI225637459, Length=673, Percent_Identity=22.5854383358098, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI225637461, Length=645, Percent_Identity=22.1705426356589, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI225637463, Length=644, Percent_Identity=22.6708074534161, Blast_Score=119, Evalue=9e-27,
Organism=Escherichia coli, GI48994911, Length=668, Percent_Identity=50.2994011976048, Blast_Score=641, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=664, Percent_Identity=49.8493975903614, Blast_Score=629, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=579, Percent_Identity=27.2884283246978, Blast_Score=166, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6325331, Length=679, Percent_Identity=43.1516936671576, Blast_Score=502, Evalue=1e-143,
Organism=Saccharomyces cerevisiae, GI6319593, Length=673, Percent_Identity=41.6047548291233, Blast_Score=491, Evalue=1e-139,
Organism=Drosophila melanogaster, GI45551847, Length=580, Percent_Identity=28.1034482758621, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI45550715, Length=580, Percent_Identity=28.1034482758621, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24645119, Length=548, Percent_Identity=27.7372262773723, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24666278, Length=574, Percent_Identity=25.0871080139373, Blast_Score=159, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 73434; Mature: 73303

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTFSRALPSPQTPTFGGTMTSREQHDRMANAIRFLSMDAVEKAQSGHPGLPMGCADIA
CCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
TVLFTRFLKYDPKAPHWPDRDRFILSAGHGSMLLYSLLHLTGYEDMTIDQIKHFRQLGSK
HHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
TAGHPEYGHATGIETTTGPLGQGLANSVGFALGERIMNAAFGNDLVSHYTYVLAGDGCLM
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHH
EGVSQEAIALAGHLKLNKLIVFWDNNNISIDGPVSLADNTDQVARFQASGWNASHIDGTD
HCCCHHHHHHHCCEEEEEEEEEECCCEEEECCCEEECCCCHHHHEEECCCCCCCCCCCCC
PEAIAYAIEAARHSDKPTMIACKTTIGFGAPTKAGTNKAHGSPLGADEIAGARKFFNWES
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
PPFEIPADILDAWRTAGKAGAKPRADWEGRLAKAEPKLKAEFERRLAGKLPSNFDAVIAD
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
YKKKLSADKPKVATRKSSEMALEVINGAVPETIGGSADLTGSNNTKTSQTKNITPDDYGQ
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
RYVHYGIREHGMAAAINGLTLHGGLIAYGGTFMCFSDYARPSMRLSSLMGIRSIFVMTHD
HHHHHCHHHCCCCCEECCEEEECCEEECCCEEEEEHHCCCHHHHHHHHHHHHHEEEEECC
SIGLGEDGPTHQPVEHLAALRAIPNHNVFRPADAVETAECWQIALESEKTPSTLALTRQN
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCC
LPTVRIEHSAKNLSSQGAYELAAASGEAAVTIFATGSEVEIALGARDLLEKHGHPTRVVS
CCEEEEECCHHCCCCCCCEEEEECCCCEEEEEEECCCEEEEEECHHHHHHHCCCCCEEEE
VPCFELFDKQSDDYRKKTIGNAPIKMAIEAGIRQGWDHLIGSDGIFVGMTGFGASGTIEQ
CCHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
LYPHFGITAEAAAKAAEARLHAK
HCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRTFSRALPSPQTPTFGGTMTSREQHDRMANAIRFLSMDAVEKAQSGHPGLPMGCADIA
CCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
TVLFTRFLKYDPKAPHWPDRDRFILSAGHGSMLLYSLLHLTGYEDMTIDQIKHFRQLGSK
HHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
TAGHPEYGHATGIETTTGPLGQGLANSVGFALGERIMNAAFGNDLVSHYTYVLAGDGCLM
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHH
EGVSQEAIALAGHLKLNKLIVFWDNNNISIDGPVSLADNTDQVARFQASGWNASHIDGTD
HCCCHHHHHHHCCEEEEEEEEEECCCEEEECCCEEECCCCHHHHEEECCCCCCCCCCCCC
PEAIAYAIEAARHSDKPTMIACKTTIGFGAPTKAGTNKAHGSPLGADEIAGARKFFNWES
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
PPFEIPADILDAWRTAGKAGAKPRADWEGRLAKAEPKLKAEFERRLAGKLPSNFDAVIAD
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
YKKKLSADKPKVATRKSSEMALEVINGAVPETIGGSADLTGSNNTKTSQTKNITPDDYGQ
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
RYVHYGIREHGMAAAINGLTLHGGLIAYGGTFMCFSDYARPSMRLSSLMGIRSIFVMTHD
HHHHHCHHHCCCCCEECCEEEECCEEECCCEEEEEHHCCCHHHHHHHHHHHHHEEEEECC
SIGLGEDGPTHQPVEHLAALRAIPNHNVFRPADAVETAECWQIALESEKTPSTLALTRQN
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCC
LPTVRIEHSAKNLSSQGAYELAAASGEAAVTIFATGSEVEIALGARDLLEKHGHPTRVVS
CCEEEEECCHHCCCCCCCEEEEECCCCEEEEEEECCCEEEEEECHHHHHHHCCCCCEEEE
VPCFELFDKQSDDYRKKTIGNAPIKMAIEAGIRQGWDHLIGSDGIFVGMTGFGASGTIEQ
CCHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
LYPHFGITAEAAAKAAEARLHAK
HCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]