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The map label for this gene is xylR [H]

Identifier: 13473196

GI number: 13473196

Start: 2993136

End: 2994386

Strand: Direct

Name: xylR [H]

Synonym: mlr3714

Alternate gene names: 13473196

Gene position: 2993136-2994386 (Clockwise)

Preceding gene: 13473191

Following gene: 13473204

Centisome position: 42.54

GC content: 67.71

Gene sequence:

>1251_bases
ATGTCGGTCGGAATCCGCCACGACGATCTGCGCCGGCGCAACCGCGCCATGGTGATTGCCGCCGTGCGCCGGGCCGGTCG
GCCCTCGCGCACCGAGATCGCCGCGACCACCGGCCTCAGCCACTCGACCATATCGGCGATTTCCTCCGACCTGATCGGCG
AAGGCATACTGGCCGAGGGAAAGCCGAGCGAGGCCGGCGCGCTGAAACGCGGCAGGCCGCAGGTCGGTCTCGGCCTTAAC
CCGGAGGCCGCGGCAGTGATGACCGTGGTGCTGTCGCTGAACTTCCTCTCCGTCGCCGTCATCGATTATGCCGGCCAGGT
GATATCGGAAGAACAGCGCCGGCTGGATACGCTGACCATGTCGCGCGAGGCGCTGATCGGCGAGTGCGTGGCCATCGTAA
GGCGGCGTCTCGAGGATCCCGACATCGACGTGCGCAGCGTCGCCCGCATCGCGCTGGCGATCCAGGGCATCACCGACACC
GAGGCCCGGGCGATGCTGTGGTCGCCGATCACGCCGCAGACCGATATCGCCTTCGCCGACATACTCGAAGCCGAGTTCGG
CATCCCCGCAACCATGGAAAACGACTGCAACATGATGGCCGTGGCGCTGCGCTGGCGCGATCCCGAGCGCTACCGCGACG
ACTTCATCGCCATCCTTTTGTCGCACGGCATCGGCATGGGGCTGGTGCTGAAGGGCGAGCTGTTCACCGGCACCCATTCC
TCGGGCGGCGAGTTCGGCCACATGATCCATCGGCCGGGCGGCGCGCTCTGCCGCTGCGGGCGGCGCGGCTGCGTCGAGGC
CTATGCCGGCAATTATGCCATCTGGCGCAACGCCAGGCAGCTCAGCGAGGACACCGAGCCGGTGGCCGATGTCAGCGACG
CGCAGATGCGGGCGCTGGCCGCGACGGCGCGCGAACGCGACGGACCCGAGCGCGAAGCCTACCGCAAGGCCGGCGAGGCA
TTGGGCTACGGCCTCGGCAGCCTGTTTGCGCTGATCGATCCAGCACCCGTTGCCATGGTCGGCGTCAGCGCCGCCGCCTT
CGACCTGATCGAGCCGGCATTGCGCGAGGCGATCGCCCAGACCGCCGGTGGCCAGCACTCGGAATCGATCTCCTTCGACA
CCGAACCGAACGAACTGCCGCTGATCCGCGAAGGTTGCGCCATGCGCGCGCTGACCTTTGTCGACCAGGAGATTTTCGCG
CCGGGCGTGCAAACGAAAGCAGGCCTTGCCGCGAAGAAAAACGTCGCCTGA

Upstream 100 bases:

>100_bases
AATGACAGGACGGGCCGCTTCTGCCAGTATTTGATCGTGTCGCCGGCAGCGTTCGAGGGAGGACCGGAAGAACCGCGGCG
ACGGGGAGGATGTGAGAAAC

Downstream 100 bases:

>100_bases
TTCAGGTCGTGCTCAATCCTCGCGGATCGCGTAGCCCGCCCCACGAATGGTTCTGATAACATCCGGCATGCGGCCATTGT
TGACCGCCTTGCGCAGGCGG

Product: xyl repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MSVGIRHDDLRRRNRAMVIAAVRRAGRPSRTEIAATTGLSHSTISAISSDLIGEGILAEGKPSEAGALKRGRPQVGLGLN
PEAAAVMTVVLSLNFLSVAVIDYAGQVISEEQRRLDTLTMSREALIGECVAIVRRRLEDPDIDVRSVARIALAIQGITDT
EARAMLWSPITPQTDIAFADILEAEFGIPATMENDCNMMAVALRWRDPERYRDDFIAILLSHGIGMGLVLKGELFTGTHS
SGGEFGHMIHRPGGALCRCGRRGCVEAYAGNYAIWRNARQLSEDTEPVADVSDAQMRALAATARERDGPEREAYRKAGEA
LGYGLGSLFALIDPAPVAMVGVSAAAFDLIEPALREAIAQTAGGQHSESISFDTEPNELPLIREGCAMRALTFVDQEIFA
PGVQTKAGLAAKKNVA

Sequences:

>Translated_416_residues
MSVGIRHDDLRRRNRAMVIAAVRRAGRPSRTEIAATTGLSHSTISAISSDLIGEGILAEGKPSEAGALKRGRPQVGLGLN
PEAAAVMTVVLSLNFLSVAVIDYAGQVISEEQRRLDTLTMSREALIGECVAIVRRRLEDPDIDVRSVARIALAIQGITDT
EARAMLWSPITPQTDIAFADILEAEFGIPATMENDCNMMAVALRWRDPERYRDDFIAILLSHGIGMGLVLKGELFTGTHS
SGGEFGHMIHRPGGALCRCGRRGCVEAYAGNYAIWRNARQLSEDTEPVADVSDAQMRALAATARERDGPEREAYRKAGEA
LGYGLGSLFALIDPAPVAMVGVSAAAFDLIEPALREAIAQTAGGQHSESISFDTEPNELPLIREGCAMRALTFVDQEIFA
PGVQTKAGLAAKKNVA
>Mature_415_residues
SVGIRHDDLRRRNRAMVIAAVRRAGRPSRTEIAATTGLSHSTISAISSDLIGEGILAEGKPSEAGALKRGRPQVGLGLNP
EAAAVMTVVLSLNFLSVAVIDYAGQVISEEQRRLDTLTMSREALIGECVAIVRRRLEDPDIDVRSVARIALAIQGITDTE
ARAMLWSPITPQTDIAFADILEAEFGIPATMENDCNMMAVALRWRDPERYRDDFIAILLSHGIGMGLVLKGELFTGTHSS
GGEFGHMIHRPGGALCRCGRRGCVEAYAGNYAIWRNARQLSEDTEPVADVSDAQMRALAATARERDGPEREAYRKAGEAL
GYGLGSLFALIDPAPVAMVGVSAAAFDLIEPALREAIAQTAGGQHSESISFDTEPNELPLIREGCAMRALTFVDQEIFAP
GVQTKAGLAAKKNVA

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI4885285, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI298566325, Length=182, Percent_Identity=29.1208791208791, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI190014632, Length=202, Percent_Identity=29.2079207920792, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1787878, Length=372, Percent_Identity=23.3870967741935, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1786891, Length=361, Percent_Identity=22.7146814404432, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082127, Length=355, Percent_Identity=24.2253521126761, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44618; Mature: 44486

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVGIRHDDLRRRNRAMVIAAVRRAGRPSRTEIAATTGLSHSTISAISSDLIGEGILAEG
CCCCCCCHHHHHHCHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCC
KPSEAGALKRGRPQVGLGLNPEAAAVMTVVLSLNFLSVAVIDYAGQVISEEQRRLDTLTM
CCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SREALIGECVAIVRRRLEDPDIDVRSVARIALAIQGITDTEARAMLWSPITPQTDIAFAD
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCCHHHHH
ILEAEFGIPATMENDCNMMAVALRWRDPERYRDDFIAILLSHGIGMGLVLKGELFTGTHS
HHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCC
SGGEFGHMIHRPGGALCRCGRRGCVEAYAGNYAIWRNARQLSEDTEPVADVSDAQMRALA
CCCCCCHHHCCCCHHHHHCCCCCCHHHHCCCCHHHHCHHHHHCCCCCCCCCCHHHHHHHH
ATARERDGPEREAYRKAGEALGYGLGSLFALIDPAPVAMVGVSAAAFDLIEPALREAIAQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TAGGQHSESISFDTEPNELPLIREGCAMRALTFVDQEIFAPGVQTKAGLAAKKNVA
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCC
>Mature Secondary Structure 
SVGIRHDDLRRRNRAMVIAAVRRAGRPSRTEIAATTGLSHSTISAISSDLIGEGILAEG
CCCCCCHHHHHHCHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCC
KPSEAGALKRGRPQVGLGLNPEAAAVMTVVLSLNFLSVAVIDYAGQVISEEQRRLDTLTM
CCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SREALIGECVAIVRRRLEDPDIDVRSVARIALAIQGITDTEARAMLWSPITPQTDIAFAD
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCCHHHHH
ILEAEFGIPATMENDCNMMAVALRWRDPERYRDDFIAILLSHGIGMGLVLKGELFTGTHS
HHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCC
SGGEFGHMIHRPGGALCRCGRRGCVEAYAGNYAIWRNARQLSEDTEPVADVSDAQMRALA
CCCCCCHHHCCCCHHHHHCCCCCCHHHHCCCCHHHHCHHHHHCCCCCCCCCCHHHHHHHH
ATARERDGPEREAYRKAGEALGYGLGSLFALIDPAPVAMVGVSAAAFDLIEPALREAIAQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TAGGQHSESISFDTEPNELPLIREGCAMRALTFVDQEIFAPGVQTKAGLAAKKNVA
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]