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The map label for this gene is ygjG [C]

Identifier: 13473158

GI number: 13473158

Start: 2956775

End: 2958193

Strand: Reverse

Name: ygjG [C]

Synonym: mll3663

Alternate gene names: 13473158

Gene position: 2958193-2956775 (Counterclockwise)

Preceding gene: 13473162

Following gene: 13473156

Centisome position: 42.04

GC content: 63.85

Gene sequence:

>1419_bases
ATGGCTGCGGTGAGAGACCTGAAGGCGACCGAAATGGCAGCGTCCGGCGGTGACGATGCCATTGAACTGGGCAAGCGCCA
TCTCATCCAGCCCTGGCCTTATGCCGGTTCCGTCGGTGCCGAAGCCCGCGCGCTGATTGGCGAAGGCGACGGCATATACA
TCACCGACAACACCGGCAAGCGGCTGATCGACGGGCCTGCCGGCATGTGGTGCGTCAATGTCGGCCACCGCCGCGAGGAA
CTGGCCAGGGTGATGTACGACCAGGCGATGGCGCTGTCCTACAACACGCCCTGGTACACGATGAACGCGCCGTCGGCCGA
ACTTGCCATGCGTATCGCCGGCCATGCGCCTGATGATCTCAGCCATGTCTTCTATACGACCGGCGGCTCTTCGGCCGTGG
AGACGGCGCTGCGCTTCATGCAGTTCTACAACAATGTGCGCGGCCGGCCGGAAAAGAAGCTGATCCTGTCGCGCGGCGGC
GCCTATCATGGCTCAACCTATCTATCGGCCTCGCTCAATGGCCGCCCGCGCGACCGCGACTGGATGGACGGCGCCGACGA
GCTGGTGATCAAACTGTCCTCTCCCGATCCGTTCCGCCGCCCGCAAGGCATGAGCCTTGCCGCCTTCACCGACTTCCTCG
TCGACCAGTTCCGCGACACGGTCGCCCGTGTCGGCGCAGACAAAATCGGCGCTTTCGTCGGCGAGCCGGTGCAAGCATCG
GGAGGCGTCGTGATCCCGCCCGACGGCTATCTCAAGCGCATCCGCGAGATCTGCCGCGTCAACGATATCCTCTACGTCTC
CGACGAGGTGGTGACGGGCTTCGGCCGGCTTGGCCATGTCTTCGCCTCGGGTGACGTGTTCGGCATCGATCCCGACATGA
TCACCTTCGCCAAGGGCGTCACCTCAGGCTATTTCCCGCTCGGCGGCGTCATCATCTCGGAACGGCTGCTGCAGGAGTTG
CGCCGTTCGAACCATCCCGATGCGATGTTCGGCCATGGCTTGACCTATACCAGCCATCCCGTCGGCTGTGCCGTGGCGCT
GAAAAACCTCGACCTGCTGGAAGAGAGCGTGCTTGCCCATACGCAGGCGGTCGCGCCCTATTTCCAGGCGCAGCTGAAGA
CGCTGGAAGAGCTGCCGCTGGTCGGCGAGGTGCGCGGCGCCGGGCTGATGGGCTGCGTCGAATGCGTCGCCGACCGCGAA
AGCAAGAACCCGCTGCAGCTCGACAAGGATGTCGGCAAACGCATCGACGCCCACTGCCATGAGCTCGGCCTGCTGGTACG
GCCACTGATCAACATGTGCGTGATGTCGCCGCCGCTGATCATCACGCGCGAGCAGATCGACGACATGGTCGGCATTTTGC
GCGAAGGCATTTCGCGGACCATGGATGATCTGTGGAAAGAGGGCGTGTGGCGGGGGTAA

Upstream 100 bases:

>100_bases
TGAATGGACATTCAAAATTAGGTGAAGAAAGCCGGCATTTCCGGCCATTGCCGCCGAATTTGAGGTCCAAGAAATAATCG
ACAGAGATGTGGAGACGACA

Downstream 100 bases:

>100_bases
CATCATTCCTTCTCCCCGTTTCACGGGGAGAAGGAAGCTACGACCGCGACCTCAGCGCGTCGTTCAAATTCCACATGTCC
TTCTCCTCCGGCGCCGTCTC

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MAAVRDLKATEMAASGGDDAIELGKRHLIQPWPYAGSVGAEARALIGEGDGIYITDNTGKRLIDGPAGMWCVNVGHRREE
LARVMYDQAMALSYNTPWYTMNAPSAELAMRIAGHAPDDLSHVFYTTGGSSAVETALRFMQFYNNVRGRPEKKLILSRGG
AYHGSTYLSASLNGRPRDRDWMDGADELVIKLSSPDPFRRPQGMSLAAFTDFLVDQFRDTVARVGADKIGAFVGEPVQAS
GGVVIPPDGYLKRIREICRVNDILYVSDEVVTGFGRLGHVFASGDVFGIDPDMITFAKGVTSGYFPLGGVIISERLLQEL
RRSNHPDAMFGHGLTYTSHPVGCAVALKNLDLLEESVLAHTQAVAPYFQAQLKTLEELPLVGEVRGAGLMGCVECVADRE
SKNPLQLDKDVGKRIDAHCHELGLLVRPLINMCVMSPPLIITREQIDDMVGILREGISRTMDDLWKEGVWRG

Sequences:

>Translated_472_residues
MAAVRDLKATEMAASGGDDAIELGKRHLIQPWPYAGSVGAEARALIGEGDGIYITDNTGKRLIDGPAGMWCVNVGHRREE
LARVMYDQAMALSYNTPWYTMNAPSAELAMRIAGHAPDDLSHVFYTTGGSSAVETALRFMQFYNNVRGRPEKKLILSRGG
AYHGSTYLSASLNGRPRDRDWMDGADELVIKLSSPDPFRRPQGMSLAAFTDFLVDQFRDTVARVGADKIGAFVGEPVQAS
GGVVIPPDGYLKRIREICRVNDILYVSDEVVTGFGRLGHVFASGDVFGIDPDMITFAKGVTSGYFPLGGVIISERLLQEL
RRSNHPDAMFGHGLTYTSHPVGCAVALKNLDLLEESVLAHTQAVAPYFQAQLKTLEELPLVGEVRGAGLMGCVECVADRE
SKNPLQLDKDVGKRIDAHCHELGLLVRPLINMCVMSPPLIITREQIDDMVGILREGISRTMDDLWKEGVWRG
>Mature_471_residues
AAVRDLKATEMAASGGDDAIELGKRHLIQPWPYAGSVGAEARALIGEGDGIYITDNTGKRLIDGPAGMWCVNVGHRREEL
ARVMYDQAMALSYNTPWYTMNAPSAELAMRIAGHAPDDLSHVFYTTGGSSAVETALRFMQFYNNVRGRPEKKLILSRGGA
YHGSTYLSASLNGRPRDRDWMDGADELVIKLSSPDPFRRPQGMSLAAFTDFLVDQFRDTVARVGADKIGAFVGEPVQASG
GVVIPPDGYLKRIREICRVNDILYVSDEVVTGFGRLGHVFASGDVFGIDPDMITFAKGVTSGYFPLGGVIISERLLQELR
RSNHPDAMFGHGLTYTSHPVGCAVALKNLDLLEESVLAHTQAVAPYFQAQLKTLEELPLVGEVRGAGLMGCVECVADRES
KNPLQLDKDVGKRIDAHCHELGLLVRPLINMCVMSPPLIITREQIDDMVGILREGISRTMDDLWKEGVWRG

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=481, Percent_Identity=27.8586278586279, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI37574042, Length=440, Percent_Identity=27.0454545454545, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI226442705, Length=437, Percent_Identity=27.0022883295195, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226442709, Length=415, Percent_Identity=26.9879518072289, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI24119277, Length=365, Percent_Identity=27.1232876712329, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI4557809, Length=416, Percent_Identity=25.2403846153846, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI284507298, Length=232, Percent_Identity=29.3103448275862, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI145693181, Length=415, Percent_Identity=26.7469879518072, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1786991, Length=447, Percent_Identity=27.7404921700224, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788044, Length=406, Percent_Identity=28.3251231527094, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789016, Length=407, Percent_Identity=27.5184275184275, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1789759, Length=349, Percent_Identity=28.6532951289398, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787560, Length=416, Percent_Identity=26.4423076923077, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32564660, Length=444, Percent_Identity=29.5045045045045, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25144271, Length=452, Percent_Identity=23.8938053097345, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25144274, Length=283, Percent_Identity=27.208480565371, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71992977, Length=424, Percent_Identity=25, Blast_Score=108, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6324386, Length=424, Percent_Identity=25.2358490566038, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6323470, Length=429, Percent_Identity=24.7086247086247, Blast_Score=116, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6324432, Length=420, Percent_Identity=25.952380952381, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI161085790, Length=445, Percent_Identity=28.9887640449438, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI28574759, Length=445, Percent_Identity=28.9887640449438, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI21357415, Length=424, Percent_Identity=25, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21356575, Length=448, Percent_Identity=26.1160714285714, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 51593; Mature: 51461

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVRDLKATEMAASGGDDAIELGKRHLIQPWPYAGSVGAEARALIGEGDGIYITDNTGK
CCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHEEECCCEEEEECCCCC
RLIDGPAGMWCVNVGHRREELARVMYDQAMALSYNTPWYTMNAPSAELAMRIAGHAPDDL
EEECCCCCEEEECCCHHHHHHHHHHHHHHHEEEECCCEEEECCCHHHHHHHHCCCCCCCC
SHVFYTTGGSSAVETALRFMQFYNNVRGRPEKKLILSRGGAYHGSTYLSASLNGRPRDRD
CEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCCCCEEEEEECCCCCCCCC
WMDGADELVIKLSSPDPFRRPQGMSLAAFTDFLVDQFRDTVARVGADKIGAFVGEPVQAS
CCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCC
GGVVIPPDGYLKRIREICRVNDILYVSDEVVTGFGRLGHVFASGDVFGIDPDMITFAKGV
CCEEECCCHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHEEECCCEEECCCCHHHHHHHC
TSGYFPLGGVIISERLLQELRRSNHPDAMFGHGLTYTSHPVGCAVALKNLDLLEESVLAH
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TQAVAPYFQAQLKTLEELPLVGEVRGAGLMGCVECVADRESKNPLQLDKDVGKRIDAHCH
HHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ELGLLVRPLINMCVMSPPLIITREQIDDMVGILREGISRTMDDLWKEGVWRG
HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AAVRDLKATEMAASGGDDAIELGKRHLIQPWPYAGSVGAEARALIGEGDGIYITDNTGK
CCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHEEECCCEEEEECCCCC
RLIDGPAGMWCVNVGHRREELARVMYDQAMALSYNTPWYTMNAPSAELAMRIAGHAPDDL
EEECCCCCEEEECCCHHHHHHHHHHHHHHHEEEECCCEEEECCCHHHHHHHHCCCCCCCC
SHVFYTTGGSSAVETALRFMQFYNNVRGRPEKKLILSRGGAYHGSTYLSASLNGRPRDRD
CEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCCCCEEEEEECCCCCCCCC
WMDGADELVIKLSSPDPFRRPQGMSLAAFTDFLVDQFRDTVARVGADKIGAFVGEPVQAS
CCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCC
GGVVIPPDGYLKRIREICRVNDILYVSDEVVTGFGRLGHVFASGDVFGIDPDMITFAKGV
CCEEECCCHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHEEECCCEEECCCCHHHHHHHC
TSGYFPLGGVIISERLLQELRRSNHPDAMFGHGLTYTSHPVGCAVALKNLDLLEESVLAH
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TQAVAPYFQAQLKTLEELPLVGEVRGAGLMGCVECVADRESKNPLQLDKDVGKRIDAHCH
HHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ELGLLVRPLINMCVMSPPLIITREQIDDMVGILREGISRTMDDLWKEGVWRG
HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]