Click here to switch to the map view.

The map label for this gene is srlA [H]

Identifier: 13473118

GI number: 13473118

Start: 2914644

End: 2915336

Strand: Reverse

Name: srlA [H]

Synonym: mll3614

Alternate gene names: 13473118

Gene position: 2915336-2914644 (Counterclockwise)

Preceding gene: 13473119

Following gene: 13473117

Centisome position: 41.43

GC content: 61.18

Gene sequence:

>693_bases
ATGGTCTCGGATGCTGCATTGCATGGCAAGCTCGCCGTCGAGCATGCTTCCGACCATCTCGTTGTCCTGGCGCAAGCAGA
CAGCGGACCCATAACCGTCGATCAGTTCAAGGAAAAGCTGAAGGAAGTCCAGCAGGAAGAGCAGCTCGGCTGGCTGACCG
CCATCGGCAAGTACTTCATCGGCATCTTCCAGAAGGGCGGCGAAGTGTTCGCCGGCTTCGTCACCGGCATCATTCCGACG
CTGGTGGTGCTGATGACCGCCTTCTACGCCGTCACCGAACTGGTCGGCGAGGAGCGCGTGCATGGCCTGGCGCGCGGCGC
CGGCAGGATTGCCTTGACCCGCTATACGCTGCTGCCGCTGCTGGCGGTGTTCTTCCTCACCAATCCGATGGCCTACACGT
TCGGATCGTTTCTGGAAGAAAAGCACAAGCCGGCCTTCTATGACGCGGCCGTGTCCTACGTGCATCCGCCGCTCGGCCTG
TTCCCGCACATCAATCCCGGCGAATATTTCGTCTGGGGCGGCATTCTCGTGGCTCTGCTCGAGCTCGAGAAAAAGGGCGT
TGTCGTCGCCGGTTACCACGTCAAAGTGGCGATCTGGTACGCCATTGTCGGCCTCGTCGTCATCCTGCTCAAGGGCATGC
TGACCGAGCGCATCACCACCATCATGGCACGCCGCCAGGGCGTCGAGCTGTAA

Upstream 100 bases:

>100_bases
GGATAACCGGCGGGCGGCATAAGGAGGAGAAATGTCTGTATTTTCGTTGTTGGCGCAGCATGCCGACATGGCCGTGCACA
ATCTGCATGTCGCAGGTGCC

Downstream 100 bases:

>100_bases
GGGCGGGGAGGACATCATGGACAGGACATTCAAAGCCGTAAAGATCTCCCGGGGCAACACAGGCTGGGGCGGCCCGCTCG
TCATCGAGCCGACCGCGCAG

Product: phosphotransferase system enzyme II, C2 component (permease)

Products: D-sorbitol 6-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gut; PTS system glucitol/sorbitol-specific EIIC component [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MVSDAALHGKLAVEHASDHLVVLAQADSGPITVDQFKEKLKEVQQEEQLGWLTAIGKYFIGIFQKGGEVFAGFVTGIIPT
LVVLMTAFYAVTELVGEERVHGLARGAGRIALTRYTLLPLLAVFFLTNPMAYTFGSFLEEKHKPAFYDAAVSYVHPPLGL
FPHINPGEYFVWGGILVALLELEKKGVVVAGYHVKVAIWYAIVGLVVILLKGMLTERITTIMARRQGVEL

Sequences:

>Translated_230_residues
MVSDAALHGKLAVEHASDHLVVLAQADSGPITVDQFKEKLKEVQQEEQLGWLTAIGKYFIGIFQKGGEVFAGFVTGIIPT
LVVLMTAFYAVTELVGEERVHGLARGAGRIALTRYTLLPLLAVFFLTNPMAYTFGSFLEEKHKPAFYDAAVSYVHPPLGL
FPHINPGEYFVWGGILVALLELEKKGVVVAGYHVKVAIWYAIVGLVVILLKGMLTERITTIMARRQGVEL
>Mature_230_residues
MVSDAALHGKLAVEHASDHLVVLAQADSGPITVDQFKEKLKEVQQEEQLGWLTAIGKYFIGIFQKGGEVFAGFVTGIIPT
LVVLMTAFYAVTELVGEERVHGLARGAGRIALTRYTLLPLLAVFFLTNPMAYTFGSFLEEKHKPAFYDAAVSYVHPPLGL
FPHINPGEYFVWGGILVALLELEKKGVVVAGYHVKVAIWYAIVGLVVILLKGMLTERITTIMARRQGVEL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3730

COG function: function code G; Phosphotransferase system sorbitol-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994904, Length=174, Percent_Identity=40.8045977011494, Blast_Score=136, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004699 [H]

Pfam domain/function: PF03608 EII-GUT [H]

EC number: NA

Molecular weight: Translated: 25223; Mature: 25223

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS51107 PTS_EIIC_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSDAALHGKLAVEHASDHLVVLAQADSGPITVDQFKEKLKEVQQEEQLGWLTAIGKYFI
CCCCHHHCCCEEEEECCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIFQKGGEVFAGFVTGIIPTLVVLMTAFYAVTELVGEERVHGLARGAGRIALTRYTLLPL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LAVFFLTNPMAYTFGSFLEEKHKPAFYDAAVSYVHPPLGLFPHINPGEYFVWGGILVALL
HHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ELEKKGVVVAGYHVKVAIWYAIVGLVVILLKGMLTERITTIMARRQGVEL
HHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVSDAALHGKLAVEHASDHLVVLAQADSGPITVDQFKEKLKEVQQEEQLGWLTAIGKYFI
CCCCHHHCCCEEEEECCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIFQKGGEVFAGFVTGIIPTLVVLMTAFYAVTELVGEERVHGLARGAGRIALTRYTLLPL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LAVFFLTNPMAYTFGSFLEEKHKPAFYDAAVSYVHPPLGLFPHINPGEYFVWGGILVALL
HHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ELEKKGVVVAGYHVKVAIWYAIVGLVVILLKGMLTERITTIMARRQGVEL
HHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; sorbitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + sorbitol [Periplasm] = D-sorbitol 6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9435786 [H]