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The map label for this gene is srlE [H]

Identifier: 13473117

GI number: 13473117

Start: 2913623

End: 2914627

Strand: Reverse

Name: srlE [H]

Synonym: mll3613

Alternate gene names: 13473117

Gene position: 2914627-2913623 (Counterclockwise)

Preceding gene: 13473118

Following gene: 13473116

Centisome position: 41.42

GC content: 65.97

Gene sequence:

>1005_bases
ATGGACAGGACATTCAAAGCCGTAAAGATCTCCCGGGGCAACACAGGCTGGGGCGGCCCGCTCGTCATCGAGCCGACCGC
GCAGCGCGACAAGGTCGTCTCCGTCACCGGCGGCGGCATCCATCCCGTCGCCCAACTCATCGCCGACATGACCGGCGCCA
CGGCCGTCGACGGCTTCAAGGCGCCGCCAATCGAAGGTGAGATGGCGGTGGTCGTCGTCGATTGCGGCGGCACCGCACGT
TGCGGCGTCTATCCGCGCAAGCGCATCCCGACCGTCAATCTGACGCCGGTCGGCCAGGCTGGGCCGCTCGCCCAGTTCAT
CACGGAGGACATCTACGTTTCGGGCGTGAAGCCGGCCAACGTCACTATGGCGGACGGGTCCGAGGCGGTCACCACTGCGG
GGGGAGCAGCATCGATGAGTTCAGGCAATAACACTGCTGCCGCGGCGCCACAGCCGCTGCCGAGCGAAGGCGGGCTGATC
GGCCTGATCAGCTCGATCGGCCGCGTCATGGGCCGGGTGGTCGGCATCTTCTTCAATGCCGGCCGCCGCACGATCGACCA
GGTGGTGCGCAACGTGCTGCCGTTCATGGCCTTCGTGACCATGCTCATCGGCCTGATCCTCTACACCGGCATCGGCGACG
TGCTCGCCCAGCCGATGGGGCCGCTGGCCAACAATATTGTCGGCCTGCTGATCATCTCGGCCATTTGCGGCCTGCCATTC
CTGTCGCCCATCCTCGGGCCAGGCGCCGTCATCGCGCAGGTCATCGGCGTCGCCATCATCGGCCCGCAGATCGCCAACGG
CACGATTTCGCCGGCAATGGCGCTGCCGGCGCTGTTTGCCTACAATACCCAGGTGGGTTGCGACTTCGTCCCCGTCGGCC
TGGCGCTCGGTGAAGCCAAGCCGAAGACGATCGAAATCGGTGTGCCGGCGGTGCTCATCAGCCGCCAGATCATGGGTCCG
GTCTCGGTGCTGATCGCCTGGGTCGTCAGCCTGATCGTGTTTTAA

Upstream 100 bases:

>100_bases
GGCCTCGTCGTCATCCTGCTCAAGGGCATGCTGACCGAGCGCATCACCACCATCATGGCACGCCGCCAGGGCGTCGAGCT
GTAAGGGCGGGGAGGACATC

Downstream 100 bases:

>100_bases
AAACAGTAAGGAAATGAGGTTCGCCACATGTCGGTTCTGCTGAGAACAAGGGTCACTTCCATCGGACCCGAAGTGGCGGA
TCTTGCCGAAGGGGGCGTGG

Product: phosphotransferase system enzyme II, BC component

Products: NA

Alternate protein names: EII-Gut; PTS system glucitol/sorbitol-specific EIIB component [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MDRTFKAVKISRGNTGWGGPLVIEPTAQRDKVVSVTGGGIHPVAQLIADMTGATAVDGFKAPPIEGEMAVVVVDCGGTAR
CGVYPRKRIPTVNLTPVGQAGPLAQFITEDIYVSGVKPANVTMADGSEAVTTAGGAASMSSGNNTAAAAPQPLPSEGGLI
GLISSIGRVMGRVVGIFFNAGRRTIDQVVRNVLPFMAFVTMLIGLILYTGIGDVLAQPMGPLANNIVGLLIISAICGLPF
LSPILGPGAVIAQVIGVAIIGPQIANGTISPAMALPALFAYNTQVGCDFVPVGLALGEAKPKTIEIGVPAVLISRQIMGP
VSVLIAWVVSLIVF

Sequences:

>Translated_334_residues
MDRTFKAVKISRGNTGWGGPLVIEPTAQRDKVVSVTGGGIHPVAQLIADMTGATAVDGFKAPPIEGEMAVVVVDCGGTAR
CGVYPRKRIPTVNLTPVGQAGPLAQFITEDIYVSGVKPANVTMADGSEAVTTAGGAASMSSGNNTAAAAPQPLPSEGGLI
GLISSIGRVMGRVVGIFFNAGRRTIDQVVRNVLPFMAFVTMLIGLILYTGIGDVLAQPMGPLANNIVGLLIISAICGLPF
LSPILGPGAVIAQVIGVAIIGPQIANGTISPAMALPALFAYNTQVGCDFVPVGLALGEAKPKTIEIGVPAVLISRQIMGP
VSVLIAWVVSLIVF
>Mature_334_residues
MDRTFKAVKISRGNTGWGGPLVIEPTAQRDKVVSVTGGGIHPVAQLIADMTGATAVDGFKAPPIEGEMAVVVVDCGGTAR
CGVYPRKRIPTVNLTPVGQAGPLAQFITEDIYVSGVKPANVTMADGSEAVTTAGGAASMSSGNNTAAAAPQPLPSEGGLI
GLISSIGRVMGRVVGIFFNAGRRTIDQVVRNVLPFMAFVTMLIGLILYTGIGDVLAQPMGPLANNIVGLLIISAICGLPF
LSPILGPGAVIAQVIGVAIIGPQIANGTISPAMALPALFAYNTQVGCDFVPVGLALGEAKPKTIEIGVPAVLISRQIMGP
VSVLIAWVVSLIVF

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3732

COG function: function code G; Phosphotransferase system sorbitol-specific component IIBC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994905, Length=328, Percent_Identity=47.5609756097561, Blast_Score=301, Evalue=5e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011638
- InterPro:   IPR011618
- InterPro:   IPR004702 [H]

Pfam domain/function: PF07663 EIIBC-GUT_C; PF03612 EIIBC-GUT_N [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 34027; Mature: 34027

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS51102 PTS_EIIB_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRTFKAVKISRGNTGWGGPLVIEPTAQRDKVVSVTGGGIHPVAQLIADMTGATAVDGFK
CCCCEEEEEEECCCCCCCCCEEECCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCC
APPIEGEMAVVVVDCGGTARCGVYPRKRIPTVNLTPVGQAGPLAQFITEDIYVSGVKPAN
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHEECCCCCCE
VTMADGSEAVTTAGGAASMSSGNNTAAAAPQPLPSEGGLIGLISSIGRVMGRVVGIFFNA
EEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GRRTIDQVVRNVLPFMAFVTMLIGLILYTGIGDVLAQPMGPLANNIVGLLIISAICGLPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHCCHH
LSPILGPGAVIAQVIGVAIIGPQIANGTISPAMALPALFAYNTQVGCDFVPVGLALGEAK
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEHHHEECCCC
PKTIEIGVPAVLISRQIMGPVSVLIAWVVSLIVF
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDRTFKAVKISRGNTGWGGPLVIEPTAQRDKVVSVTGGGIHPVAQLIADMTGATAVDGFK
CCCCEEEEEEECCCCCCCCCEEECCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCC
APPIEGEMAVVVVDCGGTARCGVYPRKRIPTVNLTPVGQAGPLAQFITEDIYVSGVKPAN
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHEECCCCCCE
VTMADGSEAVTTAGGAASMSSGNNTAAAAPQPLPSEGGLIGLISSIGRVMGRVVGIFFNA
EEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GRRTIDQVVRNVLPFMAFVTMLIGLILYTGIGDVLAQPMGPLANNIVGLLIISAICGLPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHCCHH
LSPILGPGAVIAQVIGVAIIGPQIANGTISPAMALPALFAYNTQVGCDFVPVGLALGEAK
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEHHHEECCCC
PKTIEIGVPAVLISRQIMGPVSVLIAWVVSLIVF
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9435786 [H]