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The map label for this gene is aroB

Identifier: 13473082

GI number: 13473082

Start: 2878204

End: 2879340

Strand: Reverse

Name: aroB

Synonym: mll3571

Alternate gene names: 13473082

Gene position: 2879340-2878204 (Counterclockwise)

Preceding gene: 13473083

Following gene: 13473081

Centisome position: 40.92

GC content: 66.4

Gene sequence:

>1137_bases
GTGAGCGCGGACCAGCCAGTCACCGTCGAAGTCGGCCTTGGCGACCGGGCCTACGACATATTGATCGGCTCCGGCCTTTT
GTCGCGCGCCGGCGAAGAGATTTCGCGCCGGCTGCCGGGTACGCGCGCGGCTGTCGTCACCGACGAGAATGTCGCTGCCG
CGCATCTCGATACGTTGAAGGCAGGGCTCGAGAAGGGTGGCATCCAGCCCACCGTCATCACGATGCCGCCCGGCGAGAAG
ACCAAGAGCTTTGCCCATCTCGAAGAGGTGGTCGATGGGATTCTGGCCGCAAGGCTGGAGCGTGGCGACGTCGTCATCGC
GCTGGGCGGCGGCGTCATCGGCGATCTCACCGGTTTTTCCGCGGGCATCGTGCGGCGCGGCATGAATTTCGTACAGGTCC
CGACCTCGCTGCTGGCGCAGGTCGATTCCTCGGTGGGCGGCAAGACCGGCATCAACAGCCCGCGCGGCAAGAACCTTGTC
GGCGTCTTCCTGCAGCCGAAACTGGTGCTGGCCGACACGGAAGTGCTCGACACGCTGCCGATCCGCGAATTCCGCGCCGG
CTATGCCGAACTCGCCAAGTACGGGCTGATCGACCGGCCGGAACTTTTCGCTTGGCTGGAGGCGAACTGGCAGAAGGTGT
TCGCCGGCGGGCCGGAGCGAGCGCAGGCGATTGCCGAAGCCTGCCGCGCCAAGGCCGATGTCGTCGCGCGCGACGAGTTC
GAGACCGGCGACCGGGCGCTCCTCAATCTCGGCCACACATTCGGCCATGCGCTCGAAGCCGCCACGCAGTATGACGGCGC
CCGCCTCGTCCATGGCGAGGGGGTCGCCATCGGCATGGCGCTGGCGCATCGCTTCTCCTCGCGGCTCAATCTGGCCAGCC
CCGACGACGCGGCACGCGTCGAGACGCATCTGCGCGCCGTTGGCCTGCCGTGGCGGATGGCCGATATTCCAGGTGAATTG
CCCGATGCCGAGGCGCTGCTTGCCTTCATCACCCAGGACAAGAAGGTTTCGCGCGGCGCGCTGACCTTCATCCTGACGCG
CGGCATCGGCCAGGCTTTCATCGCCAAGGACGTTCCGGCTTCGGAAGTGCTGTCGTTCCTGAGGGAAAACCATCCAACCA
GCCGGAAAGCCGGCTGA

Upstream 100 bases:

>100_bases
CCCGCGACGACCGCAAGGAAGTCATCGCTGCCGAGGTGCTGAATGCGCTGTGCCGGCATTTCGGCATCGATGAAATTGCA
GCGACGGGCGAGATCGAATC

Downstream 100 bases:

>100_bases
AATGGACAACGGCTGGGTCGTCGTCGCCGTTCTTGCCATCCTCATCCTGCTGGTCATTGCCGTGCGCACGCGTCTTCTCG
CCATGTTCGGCTACGAGCTG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MSADQPVTVEVGLGDRAYDILIGSGLLSRAGEEISRRLPGTRAAVVTDENVAAAHLDTLKAGLEKGGIQPTVITMPPGEK
TKSFAHLEEVVDGILAARLERGDVVIALGGGVIGDLTGFSAGIVRRGMNFVQVPTSLLAQVDSSVGGKTGINSPRGKNLV
GVFLQPKLVLADTEVLDTLPIREFRAGYAELAKYGLIDRPELFAWLEANWQKVFAGGPERAQAIAEACRAKADVVARDEF
ETGDRALLNLGHTFGHALEAATQYDGARLVHGEGVAIGMALAHRFSSRLNLASPDDAARVETHLRAVGLPWRMADIPGEL
PDAEALLAFITQDKKVSRGALTFILTRGIGQAFIAKDVPASEVLSFLRENHPTSRKAG

Sequences:

>Translated_378_residues
MSADQPVTVEVGLGDRAYDILIGSGLLSRAGEEISRRLPGTRAAVVTDENVAAAHLDTLKAGLEKGGIQPTVITMPPGEK
TKSFAHLEEVVDGILAARLERGDVVIALGGGVIGDLTGFSAGIVRRGMNFVQVPTSLLAQVDSSVGGKTGINSPRGKNLV
GVFLQPKLVLADTEVLDTLPIREFRAGYAELAKYGLIDRPELFAWLEANWQKVFAGGPERAQAIAEACRAKADVVARDEF
ETGDRALLNLGHTFGHALEAATQYDGARLVHGEGVAIGMALAHRFSSRLNLASPDDAARVETHLRAVGLPWRMADIPGEL
PDAEALLAFITQDKKVSRGALTFILTRGIGQAFIAKDVPASEVLSFLRENHPTSRKAG
>Mature_377_residues
SADQPVTVEVGLGDRAYDILIGSGLLSRAGEEISRRLPGTRAAVVTDENVAAAHLDTLKAGLEKGGIQPTVITMPPGEKT
KSFAHLEEVVDGILAARLERGDVVIALGGGVIGDLTGFSAGIVRRGMNFVQVPTSLLAQVDSSVGGKTGINSPRGKNLVG
VFLQPKLVLADTEVLDTLPIREFRAGYAELAKYGLIDRPELFAWLEANWQKVFAGGPERAQAIAEACRAKADVVARDEFE
TGDRALLNLGHTFGHALEAATQYDGARLVHGEGVAIGMALAHRFSSRLNLASPDDAARVETHLRAVGLPWRMADIPGELP
DAEALLAFITQDKKVSRGALTFILTRGIGQAFIAKDVPASEVLSFLRENHPTSRKAG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=358, Percent_Identity=44.1340782122905, Blast_Score=258, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6320332, Length=373, Percent_Identity=33.5120643431635, Blast_Score=179, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_RHILO (Q98FY1)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104649.1
- ProteinModelPortal:   Q98FY1
- SMR:   Q98FY1
- GeneID:   1227310
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll3571
- NMPDR:   fig|266835.1.peg.2753
- HOGENOM:   HBG632303
- OMA:   EHAIATS
- ProtClustDB:   PRK00002
- BRENDA:   4.2.3.4
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 40134; Mature: 40003

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADQPVTVEVGLGDRAYDILIGSGLLSRAGEEISRRLPGTRAAVVTDENVAAAHLDTLK
CCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
AGLEKGGIQPTVITMPPGEKTKSFAHLEEVVDGILAARLERGDVVIALGGGVIGDLTGFS
HHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
AGIVRRGMNFVQVPTSLLAQVDSSVGGKTGINSPRGKNLVGVFLQPKLVLADTEVLDTLP
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCEEEEECHHHHHHCC
IREFRAGYAELAKYGLIDRPELFAWLEANWQKVFAGGPERAQAIAEACRAKADVVARDEF
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHEECCCHHHHHHHHHHHHHHHCEEECCCC
ETGDRALLNLGHTFGHALEAATQYDGARLVHGEGVAIGMALAHRFSSRLNLASPDDAARV
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHH
ETHLRAVGLPWRMADIPGELPDAEALLAFITQDKKVSRGALTFILTRGIGQAFIAKDVPA
HHHHHHHCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCCH
SEVLSFLRENHPTSRKAG
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SADQPVTVEVGLGDRAYDILIGSGLLSRAGEEISRRLPGTRAAVVTDENVAAAHLDTLK
CCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
AGLEKGGIQPTVITMPPGEKTKSFAHLEEVVDGILAARLERGDVVIALGGGVIGDLTGFS
HHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
AGIVRRGMNFVQVPTSLLAQVDSSVGGKTGINSPRGKNLVGVFLQPKLVLADTEVLDTLP
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCEEEEECHHHHHHCC
IREFRAGYAELAKYGLIDRPELFAWLEANWQKVFAGGPERAQAIAEACRAKADVVARDEF
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHEECCCHHHHHHHHHHHHHHHCEEECCCC
ETGDRALLNLGHTFGHALEAATQYDGARLVHGEGVAIGMALAHRFSSRLNLASPDDAARV
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHH
ETHLRAVGLPWRMADIPGELPDAEALLAFITQDKKVSRGALTFILTRGIGQAFIAKDVPA
HHHHHHHCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCCH
SEVLSFLRENHPTSRKAG
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968