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The map label for this gene is cobT [H]

Identifier: 13473074

GI number: 13473074

Start: 2870157

End: 2872055

Strand: Reverse

Name: cobT [H]

Synonym: mll3561

Alternate gene names: 13473074

Gene position: 2872055-2870157 (Counterclockwise)

Preceding gene: 13473075

Following gene: 13473073

Centisome position: 40.82

GC content: 66.25

Gene sequence:

>1899_bases
ATGGCGGGTCCGGGCGACAACACGCGCAACAAGTCGAAGACGGGGTCTGAAGCCGACAGCTTCAAGCGCGCCGTCACCGT
CTGCATGCGCGCCATTGCCGGCGACAAGGACATGGAGGTCGGCTTCGCCAAGGACAGGCCGGCGCTTGCCGGCAGCCGCG
CCCGACTGCCCGAACTGCCGAAGAAGGCCTCCAAGACCGATATTGCGATCACCCGCGGCCTCGGCGATTCCATGGCGCTC
AAGCGCGCCTGCCATGATGCCCGCATCCACAGCAAGCTGGCGCCGGAAGGCAAGGCGGCGCGCGCCATCTATGACGCGGT
CGAGCAGGCCCGCGTCGAGGCGATCGGCAGCCGCGCCATGCAAGGCGTCGCCGACAATATCGGCTCGATGCTGGAGGACA
AATACGCCAAGGCCAATCTTGTCGACGTCAAGGACAAGGCCGACGCGCCGATCGAGGAAGCGCTGGCGCTCATGGTGCGC
GAGAAGCTGACCGGCCGGGCGGTCCCGAAAAGCGGCGAGCGGCTGGTCGAGCTCTGGCGTCCCTGGGTCGAGGAAAAGGC
CAAGGCCGACCTCGACGGCCTGTCCGCGAAGCTCGACGATCAGCAGGCCTTCGCCCGCGTCGTGCGCGAGATGCTCGCCT
CCATGGAGATGGCCGAGGAACTCGGCGACGACCAGGAGACGGAAGATTCCGAGGACAATGACGACAACCAGCCGCAAGGC
GATGAACAGAGCGAGGAGGGCGGGGAAGAGGATTCCGGCTCCGAGCAGTCGCAGTCCGAGGATGCCGAGGCTTCGGCCGA
TGACGAGCAGTCGTCCGAGACGGAGGCGTCCGACGCCACCGCCGACGATCTGTCCGACGACGACGATGCCGACGCCGAAA
CGCCCGGCGAGGCGCGCCGCAACGACAACCCCTTCACCAATCTTCCGAAGGAAATCGACTACAAGGTCTTCACATCAGCT
TTCGACGAGACGGTCGGCGCCGAGGAACTCTGCGAAGAGGAAGAACTCGACCGGCTGCGTGCCTTCCTCGACAAGCAACT
GGCCAATCTGTCCGGTGTCGTCGGGCGGCTGGCCAACCGGCTGCAGCGCCGGCTGATGGCGCAGCAGAACCGGTCCTGGG
ATTTCGACCTGGAAGAGGGCTACCTCGACCCGGCGCGGCTGGTGCGCGTCGTCATCGACCCGATGCAGCCGCTGTCCTTC
AAGCAGGAACGCGACACCAAATTCCGCGACACGGTGGTGACGCTGGTGCTCGACAATTCGGGCTCGATGCGCGGCCGGCC
GATCACGGTCGCCGCCACCTGTGCCGACATTCTGGCGCGCACGCTGGAACGCTGCGGCGTCTCGGTCGAGATCCTCGGCT
TCACCACGCGGGCGTGGAAAGGCGGGCAAGCGCGCGAGAAGTGGCTGAAGGACGGCAAGCCGCCGAACCCCGGCCGCCTC
AACGATCTGCGCCACATCATCTATAAGTCGGCCGACCATCCGTGGCGGCGGGCACGGCGCAATCTCGGCCTGATGATGCG
TGAAGGCCTGCTCAAGGAAAACATCGACGGCGAGGCGCTGCTGTGGGCGCACAACCGGCTGATTGCCCGGCCCGAACAGC
GCAAGATCCTGATGATGATCTCGGACGGCGCGCCGGTCGACGATTCGACGCTTTCGGTGAACCCCGGCAATTATCTCGAA
CGCCATTTGCGCGCCGTCATCGAGCTGATCGAGACGCGCTCGCCGGTGGAATTGCTGGCCATCGGCATCGGCCATGACGT
CACGCGCTATTATCGCCGCGCCGTCACCATCGTCGATGCCGAGGAACTGGCCGGCGCCATGACCGAGCAACTGGCCTCGC
TGTTTGCCGAGGAAAGCGCACGCGACACGCGGCGCGGCGGCATGCGGCGCGCCGGATGA

Upstream 100 bases:

>100_bases
CAGTGGGAAGGGCGGTTACTTTACAATCTCGGTGGAAGAGATTGTTGGCCTCCTCCGCTCTCAGCTTGGCCAACAGCCTG
TGGCGAAATAGAGATAGATA

Downstream 100 bases:

>100_bases
TCTTTTCACGCGGCGGGTTTCGGCAAACGCTCTTCGCCGCCATCGCCCTGTTCGCCGGCGTGGCGTCCGCGCCAGCCAGT
TCGGCCGGGTCGGCTGCGGT

Product: cobT protein

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobT [H]

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MAGPGDNTRNKSKTGSEADSFKRAVTVCMRAIAGDKDMEVGFAKDRPALAGSRARLPELPKKASKTDIAITRGLGDSMAL
KRACHDARIHSKLAPEGKAARAIYDAVEQARVEAIGSRAMQGVADNIGSMLEDKYAKANLVDVKDKADAPIEEALALMVR
EKLTGRAVPKSGERLVELWRPWVEEKAKADLDGLSAKLDDQQAFARVVREMLASMEMAEELGDDQETEDSEDNDDNQPQG
DEQSEEGGEEDSGSEQSQSEDAEASADDEQSSETEASDATADDLSDDDDADAETPGEARRNDNPFTNLPKEIDYKVFTSA
FDETVGAEELCEEEELDRLRAFLDKQLANLSGVVGRLANRLQRRLMAQQNRSWDFDLEEGYLDPARLVRVVIDPMQPLSF
KQERDTKFRDTVVTLVLDNSGSMRGRPITVAATCADILARTLERCGVSVEILGFTTRAWKGGQAREKWLKDGKPPNPGRL
NDLRHIIYKSADHPWRRARRNLGLMMREGLLKENIDGEALLWAHNRLIARPEQRKILMMISDGAPVDDSTLSVNPGNYLE
RHLRAVIELIETRSPVELLAIGIGHDVTRYYRRAVTIVDAEELAGAMTEQLASLFAEESARDTRRGGMRRAG

Sequences:

>Translated_632_residues
MAGPGDNTRNKSKTGSEADSFKRAVTVCMRAIAGDKDMEVGFAKDRPALAGSRARLPELPKKASKTDIAITRGLGDSMAL
KRACHDARIHSKLAPEGKAARAIYDAVEQARVEAIGSRAMQGVADNIGSMLEDKYAKANLVDVKDKADAPIEEALALMVR
EKLTGRAVPKSGERLVELWRPWVEEKAKADLDGLSAKLDDQQAFARVVREMLASMEMAEELGDDQETEDSEDNDDNQPQG
DEQSEEGGEEDSGSEQSQSEDAEASADDEQSSETEASDATADDLSDDDDADAETPGEARRNDNPFTNLPKEIDYKVFTSA
FDETVGAEELCEEEELDRLRAFLDKQLANLSGVVGRLANRLQRRLMAQQNRSWDFDLEEGYLDPARLVRVVIDPMQPLSF
KQERDTKFRDTVVTLVLDNSGSMRGRPITVAATCADILARTLERCGVSVEILGFTTRAWKGGQAREKWLKDGKPPNPGRL
NDLRHIIYKSADHPWRRARRNLGLMMREGLLKENIDGEALLWAHNRLIARPEQRKILMMISDGAPVDDSTLSVNPGNYLE
RHLRAVIELIETRSPVELLAIGIGHDVTRYYRRAVTIVDAEELAGAMTEQLASLFAEESARDTRRGGMRRAG
>Mature_631_residues
AGPGDNTRNKSKTGSEADSFKRAVTVCMRAIAGDKDMEVGFAKDRPALAGSRARLPELPKKASKTDIAITRGLGDSMALK
RACHDARIHSKLAPEGKAARAIYDAVEQARVEAIGSRAMQGVADNIGSMLEDKYAKANLVDVKDKADAPIEEALALMVRE
KLTGRAVPKSGERLVELWRPWVEEKAKADLDGLSAKLDDQQAFARVVREMLASMEMAEELGDDQETEDSEDNDDNQPQGD
EQSEEGGEEDSGSEQSQSEDAEASADDEQSSETEASDATADDLSDDDDADAETPGEARRNDNPFTNLPKEIDYKVFTSAF
DETVGAEELCEEEELDRLRAFLDKQLANLSGVVGRLANRLQRRLMAQQNRSWDFDLEEGYLDPARLVRVVIDPMQPLSFK
QERDTKFRDTVVTLVLDNSGSMRGRPITVAATCADILARTLERCGVSVEILGFTTRAWKGGQAREKWLKDGKPPNPGRLN
DLRHIIYKSADHPWRRARRNLGLMMREGLLKENIDGEALLWAHNRLIARPEQRKILMMISDGAPVDDSTLSVNPGNYLER
HLRAVIELIETRSPVELLAIGIGHDVTRYYRRAVTIVDAEELAGAMTEQLASLFAEESARDTRRGGMRRAG

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG4547

COG function: function code H; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006538
- InterPro:   IPR002035 [H]

Pfam domain/function: PF06213 CobT [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 69922; Mature: 69791

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGPGDNTRNKSKTGSEADSFKRAVTVCMRAIAGDKDMEVGFAKDRPALAGSRARLPELP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KKASKTDIAITRGLGDSMALKRACHDARIHSKLAPEGKAARAIYDAVEQARVEAIGSRAM
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QGVADNIGSMLEDKYAKANLVDVKDKADAPIEEALALMVREKLTGRAVPKSGERLVELWR
HHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
PWVEEKAKADLDGLSAKLDDQQAFARVVREMLASMEMAEELGDDQETEDSEDNDDNQPQG
HHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DEQSEEGGEEDSGSEQSQSEDAEASADDEQSSETEASDATADDLSDDDDADAETPGEARR
CCCHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
NDNPFTNLPKEIDYKVFTSAFDETVGAEELCEEEELDRLRAFLDKQLANLSGVVGRLANR
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQRRLMAQQNRSWDFDLEEGYLDPARLVRVVIDPMQPLSFKQERDTKFRDTVVTLVLDNS
HHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHCCCCCCCCCHHHCCHHHHEEEEEEECCC
GSMRGRPITVAATCADILARTLERCGVSVEILGFTTRAWKGGQAREKWLKDGKPPNPGRL
CCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCCCHHHHHHHHCCCCCCCCHH
NDLRHIIYKSADHPWRRARRNLGLMMREGLLKENIDGEALLWAHNRLIARPEQRKILMMI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHCCCCCCEEEEEE
SDGAPVDDSTLSVNPGNYLERHLRAVIELIETRSPVELLAIGIGHDVTRYYRRAVTIVDA
ECCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCHHHEEECCCHHHHHHHHHHHHEECH
EELAGAMTEQLASLFAEESARDTRRGGMRRAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AGPGDNTRNKSKTGSEADSFKRAVTVCMRAIAGDKDMEVGFAKDRPALAGSRARLPELP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KKASKTDIAITRGLGDSMALKRACHDARIHSKLAPEGKAARAIYDAVEQARVEAIGSRAM
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QGVADNIGSMLEDKYAKANLVDVKDKADAPIEEALALMVREKLTGRAVPKSGERLVELWR
HHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
PWVEEKAKADLDGLSAKLDDQQAFARVVREMLASMEMAEELGDDQETEDSEDNDDNQPQG
HHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DEQSEEGGEEDSGSEQSQSEDAEASADDEQSSETEASDATADDLSDDDDADAETPGEARR
CCCHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
NDNPFTNLPKEIDYKVFTSAFDETVGAEELCEEEELDRLRAFLDKQLANLSGVVGRLANR
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQRRLMAQQNRSWDFDLEEGYLDPARLVRVVIDPMQPLSFKQERDTKFRDTVVTLVLDNS
HHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHCCCCCCCCCHHHCCHHHHEEEEEEECCC
GSMRGRPITVAATCADILARTLERCGVSVEILGFTTRAWKGGQAREKWLKDGKPPNPGRL
CCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCCCHHHHHHHHCCCCCCCCHH
NDLRHIIYKSADHPWRRARRNLGLMMREGLLKENIDGEALLWAHNRLIARPEQRKILMMI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHCCCCCCEEEEEE
SDGAPVDDSTLSVNPGNYLERHLRAVIELIETRSPVELLAIGIGHDVTRYYRRAVTIVDA
ECCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCHHHEEECCCHHHHHHHHHHHHEECH
EELAGAMTEQLASLFAEESARDTRRGGMRRAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]