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The map label for this gene is metX

Identifier: 13473054

GI number: 13473054

Start: 2853846

End: 2855015

Strand: Direct

Name: metX

Synonym: mlr3538

Alternate gene names: 13473054

Gene position: 2853846-2855015 (Clockwise)

Preceding gene: 13473051

Following gene: 13473055

Centisome position: 40.56

GC content: 64.19

Gene sequence:

>1170_bases
ATGGCCGCTCTGCGCGCAGGAAAGACCAACAACGAGGCCGACCAGCCGTCGAGCCCGGTGTTGCGCTTCGGGGCGGACAA
GCCGCTCAAGCTCGACGCCGGCACGCTTTTGTCGCCGTTCCAGATCGCCTATCAGACCTACGGCACGCTGAACGATGCCC
GCTCCAATGCCATCCTCGTCTGCCATGCGCTGACCGGCGACCAGCATGTCGCCAACACCAATCCGGTGACCGGCAAGCCG
GGATGGTGGGAAGTGCTGATCGGCCCCGGCAGGATCATCGACACCAACCGTTTCTTCGTCATCTGCTCCAACGTCATCGG
CGGTTGTCTGGGCTCCACCGGCCCGGCCTCGACCAACCCCGCCACCGGCAAGCCCTACGGGCTCGACCTGCCGGTCATCA
CCATCCGCGATATGGTGCGCGCGCAGCAGATGCTGATCGATCATTTCGGCATCGAGAAACTGTTCTGCGTGCTCGGCGGC
TCGATGGGCGGAATGCAGGTGCTGGAATGGGCGTCGAGCTACCCCGAGCGCGTCTTTTCGGCACTGCCGATCGCCACCGG
CGCGCGCCATTCCTCGCAGAACATCGCCTTCCACGAGGTCGGCCGGCAGGCTGTCATGGCCGATCCGGACTGGCACGGCG
GCAAATATTTCGAAAACGGCAAACGCCCGGAAAAGGGCCTGGCGGTAGCGCGCATGGCCGCCCACATAACCTATCTGTCG
GAAGCCGCCCTGCACCGGAAATTCGGCCGCAATCTGCAGGATCGCGAGGCGCTGACCTTCGGCTTCGACGCCGACTTCCA
GATCGAAAGCTATCTGCGCCACCAAGGCATGACCTTCGTCGACCGCTTCGACGCCAATTCCTATCTCTACATGACGCGGT
CGATGGACTATTTCGACCTCGCCGCCGATCATGGCGGGCGGCTGGCGGATGCCTTTGCCGGCACCAAAACCCGCTTCTGC
CTGGTGTCCTTCACCTCGGATTGGTTGTTTCCGACCGAAGAGAGCCGCTCGATCGTGCACGCGCTCAACGCCGCCGGCGC
GTCCGTGTCCTTCGTCGAAATCGAGACCGACCGCGGCCACGATGCCTTCCTGCTCGACGAGCCGGAACTGTTCGCCGCCA
TCAACGGCTTCATCGGCTCCGCGGCGCGGGCGAGAGGGCTAAGCGCATGA

Upstream 100 bases:

>100_bases
CTTTGCGAAGGCAATGCCGGTTTTTTATTGTCCGCGGCCGGCCGGACGGACGCATCGACGGCGATTTTTCGCCTGATATG
ATGCAGCAGGTGAGACAAGA

Downstream 100 bases:

>100_bases
CCCCGGAAAGTTGCAGACTTTCGGGATCGGGATCATGCGCCGCGAAGGACACGACATCATGAGCGTCAACGGCAGCCAGC
GCGTCGACCTCGAGGTCGTC

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MAALRAGKTNNEADQPSSPVLRFGADKPLKLDAGTLLSPFQIAYQTYGTLNDARSNAILVCHALTGDQHVANTNPVTGKP
GWWEVLIGPGRIIDTNRFFVICSNVIGGCLGSTGPASTNPATGKPYGLDLPVITIRDMVRAQQMLIDHFGIEKLFCVLGG
SMGGMQVLEWASSYPERVFSALPIATGARHSSQNIAFHEVGRQAVMADPDWHGGKYFENGKRPEKGLAVARMAAHITYLS
EAALHRKFGRNLQDREALTFGFDADFQIESYLRHQGMTFVDRFDANSYLYMTRSMDYFDLAADHGGRLADAFAGTKTRFC
LVSFTSDWLFPTEESRSIVHALNAAGASVSFVEIETDRGHDAFLLDEPELFAAINGFIGSAARARGLSA

Sequences:

>Translated_389_residues
MAALRAGKTNNEADQPSSPVLRFGADKPLKLDAGTLLSPFQIAYQTYGTLNDARSNAILVCHALTGDQHVANTNPVTGKP
GWWEVLIGPGRIIDTNRFFVICSNVIGGCLGSTGPASTNPATGKPYGLDLPVITIRDMVRAQQMLIDHFGIEKLFCVLGG
SMGGMQVLEWASSYPERVFSALPIATGARHSSQNIAFHEVGRQAVMADPDWHGGKYFENGKRPEKGLAVARMAAHITYLS
EAALHRKFGRNLQDREALTFGFDADFQIESYLRHQGMTFVDRFDANSYLYMTRSMDYFDLAADHGGRLADAFAGTKTRFC
LVSFTSDWLFPTEESRSIVHALNAAGASVSFVEIETDRGHDAFLLDEPELFAAINGFIGSAARARGLSA
>Mature_388_residues
AALRAGKTNNEADQPSSPVLRFGADKPLKLDAGTLLSPFQIAYQTYGTLNDARSNAILVCHALTGDQHVANTNPVTGKPG
WWEVLIGPGRIIDTNRFFVICSNVIGGCLGSTGPASTNPATGKPYGLDLPVITIRDMVRAQQMLIDHFGIEKLFCVLGGS
MGGMQVLEWASSYPERVFSALPIATGARHSSQNIAFHEVGRQAVMADPDWHGGKYFENGKRPEKGLAVARMAAHITYLSE
AALHRKFGRNLQDREALTFGFDADFQIESYLRHQGMTFVDRFDANSYLYMTRSMDYFDLAADHGGRLADAFAGTKTRFCL
VSFTSDWLFPTEESRSIVHALNAAGASVSFVEIETDRGHDAFLLDEPELFAAINGFIGSAARARGLSA

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=223, Percent_Identity=41.7040358744395, Blast_Score=185, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_RHILO (Q98G09)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104621.1
- ProteinModelPortal:   Q98G09
- SMR:   Q98G09
- GeneID:   1227282
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr3538
- NMPDR:   fig|266835.1.peg.2725
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- ProtClustDB:   PRK00175
- BRENDA:   2.3.1.31
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 42364; Mature: 42233

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 161-161 ACT_SITE 360-360

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALRAGKTNNEADQPSSPVLRFGADKPLKLDAGTLLSPFQIAYQTYGTLNDARSNAILV
CCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEE
CHALTGDQHVANTNPVTGKPGWWEVLIGPGRIIDTNRFFVICSNVIGGCLGSTGPASTNP
EEEECCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCEEEEECHHHHHHCCCCCCCCCCC
ATGKPYGLDLPVITIRDMVRAQQMLIDHFGIEKLFCVLGGSMGGMQVLEWASSYPERVFS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ALPIATGARHSSQNIAFHEVGRQAVMADPDWHGGKYFENGKRPEKGLAVARMAAHITYLS
HCCCCCCCCCCCCCCHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EAALHRKFGRNLQDREALTFGFDADFQIESYLRHQGMTFVDRFDANSYLYMTRSMDYFDL
HHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHCCCEEEEECCCCCEEEEECCCCHHHH
AADHGGRLADAFAGTKTRFCLVSFTSDWLFPTEESRSIVHALNAAGASVSFVEIETDRGH
HCCCCCCCHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCC
DAFLLDEPELFAAINGFIGSAARARGLSA
CEEEECCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AALRAGKTNNEADQPSSPVLRFGADKPLKLDAGTLLSPFQIAYQTYGTLNDARSNAILV
CCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEE
CHALTGDQHVANTNPVTGKPGWWEVLIGPGRIIDTNRFFVICSNVIGGCLGSTGPASTNP
EEEECCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCEEEEECHHHHHHCCCCCCCCCCC
ATGKPYGLDLPVITIRDMVRAQQMLIDHFGIEKLFCVLGGSMGGMQVLEWASSYPERVFS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ALPIATGARHSSQNIAFHEVGRQAVMADPDWHGGKYFENGKRPEKGLAVARMAAHITYLS
HCCCCCCCCCCCCCCHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EAALHRKFGRNLQDREALTFGFDADFQIESYLRHQGMTFVDRFDANSYLYMTRSMDYFDL
HHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHCCCEEEEECCCCCEEEEECCCCHHHH
AADHGGRLADAFAGTKTRFCLVSFTSDWLFPTEESRSIVHALNAAGASVSFVEIETDRGH
HCCCCCCCHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCC
DAFLLDEPELFAAINGFIGSAARARGLSA
CEEEECCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968