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The map label for this gene is argJ

Identifier: 13472991

GI number: 13472991

Start: 2789348

End: 2790589

Strand: Reverse

Name: argJ

Synonym: mll3461

Alternate gene names: 13472991

Gene position: 2790589-2789348 (Counterclockwise)

Preceding gene: 13472993

Following gene: 13472990

Centisome position: 39.66

GC content: 66.02

Gene sequence:

>1242_bases
ATGTCCACGACGATTTCGCCGCTCGCGCCGAAGAAGTACCCCAAAATGCCTGTCATTGAAGGGGTGCGCATCGCCACCGC
CGAAGCGGGGATAAAGTACAAGAACCGTACCGACCTGCTGGCCATGGTGTTCGATGCCGGCACTGCGGTCGCCGGCGTGT
TCACCAAGTCGAAATGCCCCTCGGCGCCCGTCGATTTCTGCCGCCAGAACCTTGCCGCCGGCAAGGCCCGGGTGCTGGTC
GTCAATTCCGGCAATGCCAACGCCTTCACCGGCAAGAAGGGCCGCGAATCCACCGCGCTGACCGGCGAGGCGGCGGCAAA
GGCTGCCGGCTGCACGGCAGGTGAGGTGTTCCTGGCCTCGACCGGCGTCATCGGCGAGCCGCTCGACACGACCAAGTTCA
GCCATCTGCTTGCCGGACTGGTCAGTGATGGCAAGCCCGACCTGTGGACCGAGGCGGCGAAGGCCATCATGACCACGGAC
ACCTATCCGAAAGTGGCGACGCAGACCGTCAAGCTTGGTGACACCGATGTCACCATCAATGGCATCTCCAAGGGCGCCGG
CATGATCGCCCCCGACATGGCGACGATGCTGTCCTTCATCGCCACCGACGCGCCGATCGCGGCCCCCGTGCTGCAGGACC
TGCTGTCGCGCGGCACGGCCAAGACCTTCAACGCGGTGACCGTCGACAGCGACACCTCGACCAGCGACACACTGCTGATC
TTCGCCACCGGCAAGGCCGCCAAGCGCGGTGCGCCTGAAATCACCGACCCGAAAGACGCACGGCTCGGTCAGTTCCGCCG
GGCGCTCGGCAAGGTGCTGAAGTCGCTGGCGCTGCAGGTGGTGCGCGACGGCGAGGGCGCCCGCAAGCAGGTCGAAGTCA
CCGTCACCGGCGCGAAATCGGCCCGCTCGGCCAAGCGCATCGCGCTGTCGATCGCCAATTCGCCGCTGGTCAAGACAGCG
GTCGCCGGCGAGGACGCCAATTGGGGCCGTGTCGTCATGGCCGTCGGCAAGGCCGGCGAGCCCGCCGACCGCGACCGGCT
GTCGATCTGGTTCGGCGATATCAGGCTGGCGCATGAGGGCGAGCGCGACCCCGGCTATTCCGAGGAAGCGACGTCGACTT
ACATGAAGCGCGACGATATCCGCATCCGTGCCGACATCGGCATCGGCCGCGGCAAGGCGACGGTGTGGACCTGCGACCTC
ACCAAGGAATATGTCGCCATCAACGGCGATTATCGGAGCTGA

Upstream 100 bases:

>100_bases
GGTCCGCCGCCCCGGCAGGCGCGGCGAAAACGCCCTTGCGCCGGCGCGCCGTATCGGGCAAACCGGCCTTCCCCTTGCGA
TTTTCCCGCCCGAGGTCCCC

Downstream 100 bases:

>100_bases
CGGTTTTGGCTTCCAGGCATCCGGCAAGCATGCTCGCGATCGTGCGCCGCTACGAGGCGGCCGGCTTTCGCGCCTGGCCG
GCGGCCGCCGTCCACTATGA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSTTISPLAPKKYPKMPVIEGVRIATAEAGIKYKNRTDLLAMVFDAGTAVAGVFTKSKCPSAPVDFCRQNLAAGKARVLV
VNSGNANAFTGKKGRESTALTGEAAAKAAGCTAGEVFLASTGVIGEPLDTTKFSHLLAGLVSDGKPDLWTEAAKAIMTTD
TYPKVATQTVKLGDTDVTINGISKGAGMIAPDMATMLSFIATDAPIAAPVLQDLLSRGTAKTFNAVTVDSDTSTSDTLLI
FATGKAAKRGAPEITDPKDARLGQFRRALGKVLKSLALQVVRDGEGARKQVEVTVTGAKSARSAKRIALSIANSPLVKTA
VAGEDANWGRVVMAVGKAGEPADRDRLSIWFGDIRLAHEGERDPGYSEEATSTYMKRDDIRIRADIGIGRGKATVWTCDL
TKEYVAINGDYRS

Sequences:

>Translated_413_residues
MSTTISPLAPKKYPKMPVIEGVRIATAEAGIKYKNRTDLLAMVFDAGTAVAGVFTKSKCPSAPVDFCRQNLAAGKARVLV
VNSGNANAFTGKKGRESTALTGEAAAKAAGCTAGEVFLASTGVIGEPLDTTKFSHLLAGLVSDGKPDLWTEAAKAIMTTD
TYPKVATQTVKLGDTDVTINGISKGAGMIAPDMATMLSFIATDAPIAAPVLQDLLSRGTAKTFNAVTVDSDTSTSDTLLI
FATGKAAKRGAPEITDPKDARLGQFRRALGKVLKSLALQVVRDGEGARKQVEVTVTGAKSARSAKRIALSIANSPLVKTA
VAGEDANWGRVVMAVGKAGEPADRDRLSIWFGDIRLAHEGERDPGYSEEATSTYMKRDDIRIRADIGIGRGKATVWTCDL
TKEYVAINGDYRS
>Mature_412_residues
STTISPLAPKKYPKMPVIEGVRIATAEAGIKYKNRTDLLAMVFDAGTAVAGVFTKSKCPSAPVDFCRQNLAAGKARVLVV
NSGNANAFTGKKGRESTALTGEAAAKAAGCTAGEVFLASTGVIGEPLDTTKFSHLLAGLVSDGKPDLWTEAAKAIMTTDT
YPKVATQTVKLGDTDVTINGISKGAGMIAPDMATMLSFIATDAPIAAPVLQDLLSRGTAKTFNAVTVDSDTSTSDTLLIF
ATGKAAKRGAPEITDPKDARLGQFRRALGKVLKSLALQVVRDGEGARKQVEVTVTGAKSARSAKRIALSIANSPLVKTAV
AGEDANWGRVVMAVGKAGEPADRDRLSIWFGDIRLAHEGERDPGYSEEATSTYMKRDDIRIRADIGIGRGKATVWTCDLT
KEYVAINGDYRS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=425, Percent_Identity=36.2352941176471, Blast_Score=233, Evalue=5e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_RHILO (Q98G72)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104558.1
- ProteinModelPortal:   Q98G72
- SMR:   Q98G72
- MEROPS:   T05.001
- GeneID:   1227219
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll3461
- NMPDR:   fig|266835.1.peg.2662
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- ProtClustDB:   PRK05388
- BRENDA:   2.3.1.1
- BRENDA:   2.3.1.35
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 43402; Mature: 43271

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTISPLAPKKYPKMPVIEGVRIATAEAGIKYKNRTDLLAMVFDAGTAVAGVFTKSKCP
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCEEEEEECCCCHHEEEEECCCCC
SAPVDFCRQNLAAGKARVLVVNSGNANAFTGKKGRESTALTGEAAAKAAGCTAGEVFLAS
CCCHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCCCEECCHHHHHHCCCCCCEEEEEE
TGVIGEPLDTTKFSHLLAGLVSDGKPDLWTEAAKAIMTTDTYPKVATQTVKLGDTDVTIN
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHEECCCCCCHHHEEEEECCCEEEEE
GISKGAGMIAPDMATMLSFIATDAPIAAPVLQDLLSRGTAKTFNAVTVDSDTSTSDTLLI
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEE
FATGKAAKRGAPEITDPKDARLGQFRRALGKVLKSLALQVVRDGEGARKQVEVTVTGAKS
EECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
ARSAKRIALSIANSPLVKTAVAGEDANWGRVVMAVGKAGEPADRDRLSIWFGDIRLAHEG
HHHHHEEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEECC
ERDPGYSEEATSTYMKRDDIRIRADIGIGRGKATVWTCDLTKEYVAINGDYRS
CCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECCCEEEEECCCCCC
>Mature Secondary Structure 
STTISPLAPKKYPKMPVIEGVRIATAEAGIKYKNRTDLLAMVFDAGTAVAGVFTKSKCP
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCEEEEEECCCCHHEEEEECCCCC
SAPVDFCRQNLAAGKARVLVVNSGNANAFTGKKGRESTALTGEAAAKAAGCTAGEVFLAS
CCCHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCCCEECCHHHHHHCCCCCCEEEEEE
TGVIGEPLDTTKFSHLLAGLVSDGKPDLWTEAAKAIMTTDTYPKVATQTVKLGDTDVTIN
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHEECCCCCCHHHEEEEECCCEEEEE
GISKGAGMIAPDMATMLSFIATDAPIAAPVLQDLLSRGTAKTFNAVTVDSDTSTSDTLLI
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEE
FATGKAAKRGAPEITDPKDARLGQFRRALGKVLKSLALQVVRDGEGARKQVEVTVTGAKS
EECCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
ARSAKRIALSIANSPLVKTAVAGEDANWGRVVMAVGKAGEPADRDRLSIWFGDIRLAHEG
HHHHHEEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEECC
ERDPGYSEEATSTYMKRDDIRIRADIGIGRGKATVWTCDLTKEYVAINGDYRS
CCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968