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The map label for this gene is glpR [H]

Identifier: 13472954

GI number: 13472954

Start: 2741295

End: 2742077

Strand: Reverse

Name: glpR [H]

Synonym: mll3414

Alternate gene names: 13472954

Gene position: 2742077-2741295 (Counterclockwise)

Preceding gene: 13472956

Following gene: 13472951

Centisome position: 38.97

GC content: 65.13

Gene sequence:

>783_bases
ATGGAGCAGAGCCGGCTGTCGAAGAAGGAGCGGCATGAGCTCATCTTGTCGGAAGTGCGCCGCTCGGCCTCGATTCGTGT
TTCCAGGCTCGCTTTGCGCCTGGGTGTCGCCGGCGAAACGATCCGGCGCGACCTTGTCGAGCTTGGCGATGCGGGGTTGC
TCAACCGAACCTATGGCGGCGCGACGATCTCGCTGGTGACATCCGAGCCGGTGATCGCCGAGCGCAGCCAGACCATGATC
GAGGAGCGGGCGCGGATCGGGCGCGGTGCGGCCGGGCTGGTCGAGAAAGGCCACATCGTGATGATCGACGGCGGCTCGAC
GACCTATGAGGTGGCGCGCGGTCTCTCGCAGTTGAAGCGGGAGCTGACGATCATCACCAACTCCATCGGCGTGGCCTCGG
TGGCCGGGGCCAATCCGAGCTTTCGGGTCATCCTTTGCCCCGGCACCTATGACAGCCGAGAAGCCAGCGTGGTCGGTGAA
GATACGGTGGAATTCGTCAGGCGCTACAATGCCGACATTGCCATCATCGGCGCGTCGAGCCTGTCCGCGGACGGGCCCAG
CGACACGATCTCGGGGGCGGCGGCGGTCAAGCGGGCGATGATCTCCCGTGCGCTGTCAACAGCGCTTGTGGTGACCAACG
ACAAGTTCGGCCGCAACAGCCTCGAACGCATCTGCACGCTCGGCGCGCTTTCCGACATCGTCACCGATCGTGAACCGCAA
CCGGCGCTGCGCGCGGTCATCGAAGCAGCCGGAACGGAACTTCACGTCTGCAGTGGCGACTGA

Upstream 100 bases:

>100_bases
TTCAACCGTTCGAATCGGGGCAGCCCAGCCGGGTCTTGCGAGACTCCTTCCCCACCGGCGTCGGCATGGATAATACTGTC
GGCTTTGCGGAGGACAGATC

Downstream 100 bases:

>100_bases
ACGGGCCGTCCGACTGTCTATGCGCGGCCGTCCATCGTCGCTCGCAACCAGGCCGTGATGGTATCGAAGTCGATCGGTTT
CGTCGTGTCGACGTCGAAGA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MEQSRLSKKERHELILSEVRRSASIRVSRLALRLGVAGETIRRDLVELGDAGLLNRTYGGATISLVTSEPVIAERSQTMI
EERARIGRGAAGLVEKGHIVMIDGGSTTYEVARGLSQLKRELTIITNSIGVASVAGANPSFRVILCPGTYDSREASVVGE
DTVEFVRRYNADIAIIGASSLSADGPSDTISGAAAVKRAMISRALSTALVVTNDKFGRNSLERICTLGALSDIVTDREPQ
PALRAVIEAAGTELHVCSGD

Sequences:

>Translated_260_residues
MEQSRLSKKERHELILSEVRRSASIRVSRLALRLGVAGETIRRDLVELGDAGLLNRTYGGATISLVTSEPVIAERSQTMI
EERARIGRGAAGLVEKGHIVMIDGGSTTYEVARGLSQLKRELTIITNSIGVASVAGANPSFRVILCPGTYDSREASVVGE
DTVEFVRRYNADIAIIGASSLSADGPSDTISGAAAVKRAMISRALSTALVVTNDKFGRNSLERICTLGALSDIVTDREPQ
PALRAVIEAAGTELHVCSGD
>Mature_260_residues
MEQSRLSKKERHELILSEVRRSASIRVSRLALRLGVAGETIRRDLVELGDAGLLNRTYGGATISLVTSEPVIAERSQTMI
EERARIGRGAAGLVEKGHIVMIDGGSTTYEVARGLSQLKRELTIITNSIGVASVAGANPSFRVILCPGTYDSREASVVGE
DTVEFVRRYNADIAIIGASSLSADGPSDTISGAAAVKRAMISRALSTALVVTNDKFGRNSLERICTLGALSDIVTDREPQ
PALRAVIEAAGTELHVCSGD

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=253, Percent_Identity=30.0395256916996, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1788069, Length=237, Percent_Identity=31.2236286919831, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1789059, Length=250, Percent_Identity=26.8, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082344, Length=255, Percent_Identity=27.0588235294118, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI226510968, Length=241, Percent_Identity=30.7053941908714, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789519, Length=237, Percent_Identity=28.6919831223629, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=25.2136752136752, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787063, Length=236, Percent_Identity=25.8474576271186, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787540, Length=250, Percent_Identity=27.2, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790635, Length=258, Percent_Identity=24.031007751938, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27618; Mature: 27618

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQSRLSKKERHELILSEVRRSASIRVSRLALRLGVAGETIRRDLVELGDAGLLNRTYGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC
ATISLVTSEPVIAERSQTMIEERARIGRGAAGLVEKGHIVMIDGGSTTYEVARGLSQLKR
EEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
ELTIITNSIGVASVAGANPSFRVILCPGTYDSREASVVGEDTVEFVRRYNADIAIIGASS
HHHHHCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCC
LSADGPSDTISGAAAVKRAMISRALSTALVVTNDKFGRNSLERICTLGALSDIVTDREPQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCC
PALRAVIEAAGTELHVCSGD
HHHHHHHHHCCCEEEEECCC
>Mature Secondary Structure
MEQSRLSKKERHELILSEVRRSASIRVSRLALRLGVAGETIRRDLVELGDAGLLNRTYGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC
ATISLVTSEPVIAERSQTMIEERARIGRGAAGLVEKGHIVMIDGGSTTYEVARGLSQLKR
EEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
ELTIITNSIGVASVAGANPSFRVILCPGTYDSREASVVGEDTVEFVRRYNADIAIIGASS
HHHHHCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCC
LSADGPSDTISGAAAVKRAMISRALSTALVVTNDKFGRNSLERICTLGALSDIVTDREPQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCC
PALRAVIEAAGTELHVCSGD
HHHHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]