Click here to switch to the map view.

The map label for this gene is cyaA [H]

Identifier: 13472848

GI number: 13472848

Start: 2621251

End: 2622666

Strand: Reverse

Name: cyaA [H]

Synonym: mll3269

Alternate gene names: 13472848

Gene position: 2622666-2621251 (Counterclockwise)

Preceding gene: 13472852

Following gene: 13472839

Centisome position: 37.27

GC content: 60.59

Gene sequence:

>1416_bases
ATGAACGAAGCTCAGGATCTGTTCTCGCTTCTGCGGCAATCGACCGATGTCGATTCACAGGCAATCGACGCGATCAAGCG
AACCATCGCGGAGGGCGAAGACCGCGAACTTTGCCGCATCAATGCGCCGGCCTTCGCCAGCAAGCATGGCCTCGACGAGG
AACGCACCATAAGCGCCTTTCTCCATGCGGCGCGGGTGGGCATCTTCGACATTTCCTGGAATGTTCTGTGCCCCGGCTGC
GGCGGCGTGCTTGACACCAACGCCACGCTGAAAACCCTGCAGAAGGACGAATACACCTGCGCGCTGTGCGCCGAGGGCTA
TTCGCCGACCCTCGACGAGATGGTCGAGGTGACATTCACCGTCAGTCCCCGCATGCGCAGAATTGCCGCCCACAATCCAC
ATGAACTGCCGTTGATGGAATATTTCCGCCAGATCTATTGGGCGTCCGGCGTCGATCTGCCGGATGAGGATTTCGTGAAA
AAGATGGAAGCGTTCTCGCTGGCGGATATCGAGCTTGCGCCCGGTGAAAAGGCGGTTCTGCCCATACAGCTTCCGTCCGA
ATTCATCATCGTCTTTGAGCCGGTCACCCATTCAGCGCAGTTCATCGACGTGAAGGGCGAACCAACAAAGGAGCGCCGAA
GCCTGTCTTTGGTCTTCGACCGCGACCATGTCCAGAACCAGACGCTGGAGATGCAACCCGGCCCGTTGCGCATTTCGCTG
GAAAACAGGACCGACACCCGCGTGCTTCCGGCAGTCTTCATCGCCGGCCAGGCATTGCATGATATCCTGGGCAAACGCCG
GCCCTTCCTCACCGCCAAGCGCCTGCTCACCAACCAGACGTTCCGCGATCTCTATCGCACGGATACGCTCGACATCAACC
AGCGCCTGAAGATCACCAGCCTGACCTTCCTGTTTACCGACCTGCGCGGATCGACCGCGCTTTACGAGCGGGTGGGCGAC
CTTTCGGCCTTCGACCTCGTACGCGCGCATTTCCAGGTTCTGCACGAGATCGTCGCGGCGGAGGCAGGCGCGGTGGTGAA
GACGATCGGTGATGCGGTGATGGCGACCTTCGCGACGCCTGATCGCGCGATTGCTGCCGCCCTCAGGATGCGCGATGCCA
TGCGTGCGCTCAACGACAAGAGCGGGCGCGAGGATCTGCTGCTCAAGATCGGAGTCCATGCCGGCCCCTGCATCGCCGTG
TCGATGAACGAGCGACAGGACTATTTCGGCCAGACGGTCAACATTGCTTCGCGGGTCCAGAACCTTGCAAACGCACAGGC
GATCTTCGCCACTCGTGCGGTGGTCGACGATAATCTCACCGCCGATCTGTTGCACAGGAACGCGCTGACGCCCGTGCCCC
ATGAGGTTTCGCTGCGCGGCATTGAGCGCGAGATAGCAGTCTACACGATCCCCTGA

Upstream 100 bases:

>100_bases
GAATGGCCGTACGGTCCGTTTCGAAGTAAAATGCAGCACCCGGACCAAGAAGCGGTCCGGTCAACACGCCTCGGGAGGCG
CATTTTCCGGAGCCTGCAGG

Downstream 100 bases:

>100_bases
AGACTTGGCCCTTGAAGTTTTGGGTCGTCTCAGCCCCTCACACGCGCCTGCAGATAAAGTAACGATCGGCGGGCACCGAA
GGCGGCGTCGGGAGGCGTTG

Product: hypothetical protein

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MNEAQDLFSLLRQSTDVDSQAIDAIKRTIAEGEDRELCRINAPAFASKHGLDEERTISAFLHAARVGIFDISWNVLCPGC
GGVLDTNATLKTLQKDEYTCALCAEGYSPTLDEMVEVTFTVSPRMRRIAAHNPHELPLMEYFRQIYWASGVDLPDEDFVK
KMEAFSLADIELAPGEKAVLPIQLPSEFIIVFEPVTHSAQFIDVKGEPTKERRSLSLVFDRDHVQNQTLEMQPGPLRISL
ENRTDTRVLPAVFIAGQALHDILGKRRPFLTAKRLLTNQTFRDLYRTDTLDINQRLKITSLTFLFTDLRGSTALYERVGD
LSAFDLVRAHFQVLHEIVAAEAGAVVKTIGDAVMATFATPDRAIAAALRMRDAMRALNDKSGREDLLLKIGVHAGPCIAV
SMNERQDYFGQTVNIASRVQNLANAQAIFATRAVVDDNLTADLLHRNALTPVPHEVSLRGIEREIAVYTIP

Sequences:

>Translated_471_residues
MNEAQDLFSLLRQSTDVDSQAIDAIKRTIAEGEDRELCRINAPAFASKHGLDEERTISAFLHAARVGIFDISWNVLCPGC
GGVLDTNATLKTLQKDEYTCALCAEGYSPTLDEMVEVTFTVSPRMRRIAAHNPHELPLMEYFRQIYWASGVDLPDEDFVK
KMEAFSLADIELAPGEKAVLPIQLPSEFIIVFEPVTHSAQFIDVKGEPTKERRSLSLVFDRDHVQNQTLEMQPGPLRISL
ENRTDTRVLPAVFIAGQALHDILGKRRPFLTAKRLLTNQTFRDLYRTDTLDINQRLKITSLTFLFTDLRGSTALYERVGD
LSAFDLVRAHFQVLHEIVAAEAGAVVKTIGDAVMATFATPDRAIAAALRMRDAMRALNDKSGREDLLLKIGVHAGPCIAV
SMNERQDYFGQTVNIASRVQNLANAQAIFATRAVVDDNLTADLLHRNALTPVPHEVSLRGIEREIAVYTIP
>Mature_471_residues
MNEAQDLFSLLRQSTDVDSQAIDAIKRTIAEGEDRELCRINAPAFASKHGLDEERTISAFLHAARVGIFDISWNVLCPGC
GGVLDTNATLKTLQKDEYTCALCAEGYSPTLDEMVEVTFTVSPRMRRIAAHNPHELPLMEYFRQIYWASGVDLPDEDFVK
KMEAFSLADIELAPGEKAVLPIQLPSEFIIVFEPVTHSAQFIDVKGEPTKERRSLSLVFDRDHVQNQTLEMQPGPLRISL
ENRTDTRVLPAVFIAGQALHDILGKRRPFLTAKRLLTNQTFRDLYRTDTLDINQRLKITSLTFLFTDLRGSTALYERVGD
LSAFDLVRAHFQVLHEIVAAEAGAVVKTIGDAVMATFATPDRAIAAALRMRDAMRALNDKSGREDLLLKIGVHAGPCIAV
SMNERQDYFGQTVNIASRVQNLANAQAIFATRAVVDDNLTADLLHRNALTPVPHEVSLRGIEREIAVYTIP

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 52441; Mature: 52441

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEAQDLFSLLRQSTDVDSQAIDAIKRTIAEGEDRELCRINAPAFASKHGLDEERTISAF
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHCCCCHHHHHHHH
LHAARVGIFDISWNVLCPGCGGVLDTNATLKTLQKDEYTCALCAEGYSPTLDEMVEVTFT
HHHHHHEEEEEECCEECCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHEEEEEE
VSPRMRRIAAHNPHELPLMEYFRQIYWASGVDLPDEDFVKKMEAFSLADIELAPGEKAVL
ECHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCEEEEEECCCCCEEE
PIQLPSEFIIVFEPVTHSAQFIDVKGEPTKERRSLSLVFDRDHVQNQTLEMQPGPLRISL
EEECCCCEEEEEECCCCCEEEEEECCCCCHHHCCEEEEEECCCCCCCEEEECCCCEEEEE
ENRTDTRVLPAVFIAGQALHDILGKRRPFLTAKRLLTNQTFRDLYRTDTLDINQRLKITS
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
LTFLFTDLRGSTALYERVGDLSAFDLVRAHFQVLHEIVAAEAGAVVKTIGDAVMATFATP
EEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
DRAIAAALRMRDAMRALNDKSGREDLLLKIGVHAGPCIAVSMNERQDYFGQTVNIASRVQ
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCHHHCCHHHHHHHHHH
NLANAQAIFATRAVVDDNLTADLLHRNALTPVPHEVSLRGIEREIAVYTIP
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MNEAQDLFSLLRQSTDVDSQAIDAIKRTIAEGEDRELCRINAPAFASKHGLDEERTISAF
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHCCCCHHHHHHHH
LHAARVGIFDISWNVLCPGCGGVLDTNATLKTLQKDEYTCALCAEGYSPTLDEMVEVTFT
HHHHHHEEEEEECCEECCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHEEEEEE
VSPRMRRIAAHNPHELPLMEYFRQIYWASGVDLPDEDFVKKMEAFSLADIELAPGEKAVL
ECHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCEEEEEECCCCCEEE
PIQLPSEFIIVFEPVTHSAQFIDVKGEPTKERRSLSLVFDRDHVQNQTLEMQPGPLRISL
EEECCCCEEEEEECCCCCEEEEEECCCCCHHHCCEEEEEECCCCCCCEEEECCCCEEEEE
ENRTDTRVLPAVFIAGQALHDILGKRRPFLTAKRLLTNQTFRDLYRTDTLDINQRLKITS
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
LTFLFTDLRGSTALYERVGDLSAFDLVRAHFQVLHEIVAAEAGAVVKTIGDAVMATFATP
EEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
DRAIAAALRMRDAMRALNDKSGREDLLLKIGVHAGPCIAVSMNERQDYFGQTVNIASRVQ
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCHHHCCHHHHHHHHHH
NLANAQAIFATRAVVDDNLTADLLHRNALTPVPHEVSLRGIEREIAVYTIP
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]